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Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low Virulence with Cytosolic Immune Signaling and Improved TB Protection.
Matthias I Gröschel
,
Fadel Sayes
,
Sung Jae Shin
,
Wafa Frigui
,
Alexandre Pawlik
,
et al.
Article dans une revue
pasteur-01503927v1
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Mycobacterial virulence: impact on immunogenicity and vaccine research
Vera Kroesen
,
Jan Madacki
,
Wafa Frigui
,
Fadel Sayes
,
Roland Brosch
Article dans une revue
pasteur-02615238v1
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Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation
Daria Bottai
,
Mariagrazia Di Luca
,
Laleh Majlessi
,
Wafa Frigui
,
Roxane Simeone
,
et al.
Article dans une revue
pasteur-02615214v1
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Phthiocerol Dimycocerosates From Mycobacterium tuberculosis Increase the Membrane Activity of Bacterial Effectors and Host Receptors
Jacques Augenstreich
,
Evert Haanappel
,
Fadel Sayes
,
Roxane Simeone
,
Valerie Guillet
,
et al.
Article dans une revue
pasteur-02873531v1
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Cytosolic Access of Mycobacterium tuberculosis: Critical Impact of Phagosomal Acidification Control and Demonstration of Occurrence In Vivo
Roxane Simeone
,
Fadel Sayes
,
Okryul Song
,
Matthias I Gröschel
,
Priscille Brodin
,
et al.
Article dans une revue
pasteur-02615223v1
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Breaching the phagosome, the case of the tuberculosis agent
Roxane Simeone
,
Fadel Sayes
,
Emeline Lawarée
,
Roland Brosch
Article dans une revue
pasteur-03413281v1
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Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 type VII secretion: encoded PE-PPE proteins predicts vaccine potential.
Fadel Sayes
,
Lin Sun
,
Mariagrazia Di Luca
,
Roxane Simeone
,
Nathalie Degaiffier
,
et al.
Article dans une revue
pasteur-01104794v1
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Basophil activation through TLR2 and TLR4 signaling pathways
Manal Alkan
,
Fadel Sayes
,
Abdulraouf Ramadan
,
François Machavoine
,
Michel Dy
,
et al.
Article dans une revue
hal-02355737v1
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ESX secretion systems: mycobacterial evolution to counter host immunity
Matthias I Gröschel
,
Fadel Sayes
,
Roxane Simeone
,
Laleh Majlessi
,
Roland Brosch
Article dans une revue
hal-02640982v1
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RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection
Louis S Ates
,
Fadel Sayes
,
Wafa Frigui
,
Roy Ummels
,
Merel P M Damen
,
et al.
Article dans une revue
pasteur-02046090v1
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Unexpected Genomic and Phenotypic Diversity of Mycobacterium africanum Lineage 5 Affects Drug Resistance, Protein Secretion, and Immunogenicity
Louis S. Ates
,
Anzaan Dippenaar
,
Fadel Sayes
,
Alexandre Pawlik
,
Christiane Bouchier
,
et al.
Article dans une revue
hal-01884644v1
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ESX-1 and phthiocerol dimycocerosates of Mycobacterium tuberculosis act in concert to cause phagosomal rupture and host cell apoptosis
Jacques Augenstreich
,
Ainhoa Arbues
,
Roxane Simeone
,
Evert Haanappel
,
Alice Wegener
,
et al.
Article dans une revue
hal-02326055v1
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Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors
Fadel Sayes
,
Catherine Blanc
,
Louis S Ates
,
Nathalie Deboosere
,
Mickael Orgeur
,
et al.
Article dans une revue
pasteur-02046037v1
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The Mycobacterium tuberculosis PhoPR virulence system regulates expression of the universal second messenger c-di-AMP and impacts vaccine safety and efficacy
Irene Pérez
,
Elena Campos-Pardos
,
Caridad Díaz
,
Santiago Uranga
,
Fadel Sayes
,
et al.
Article dans une revue
pasteur-03648358v1
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Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis
Philip Supply
,
Michael Marceau
,
Sophie Mangenot
,
David Roche
,
Carine Rouanet
,
et al.
Article dans une revue
pasteur-02615220v1
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CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection
Fadel Sayes
,
Alexandre Pawlik
,
Wafa Frigui
,
Matthias I Gröschel
,
Samuel Crommelynck
,
et al.
Article dans une revue
pasteur-02615226v1
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Live attenuated TB vaccines representing the three modern Mycobacterium tuberculosis lineages reveal that the Euro–American genetic background confers optimal vaccine potential
Irene Pérez
,
Santiago Uranga
,
Fadel Sayes
,
Wafa Frigui
,
Sofia Samper
,
et al.
Article dans une revue
pasteur-02615240v1
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TbD1 deletion as a driver of the evolutionary success of modern epidemic Mycobacterium tuberculosis lineages
Daria Bottai
,
Wafa Frigui
,
Fadel Sayes
,
Mariagrazia Di Luca
,
Dalila Spadoni
,
et al.
Article dans une revue
pasteur-02473990v1
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Colonization with Helicobacter is concomitant with modified gut microbiota and drastic failure of the immune control of Mycobacterium tuberculosis
Laleh Majlessi
,
Fadel Sayes
,
Jean-François Bureau
,
Alexandre Pawlik
,
Valérie Michel
,
et al.
Article dans une revue
hal-01652031v1
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