Frédéric Flamant

Documents

Publications

	Effect of in utero and lactational exposure to a thyroid hormone system disrupting chemical on mouse metabolome and brain transcriptome Rikke Poulsen , Yanis Zekri , Romain Guyot , Frederic Flamant , Martin Hansen Environmental Pollution, 2024, 340, pp.122783. ⟨10.1016/j.envpol.2023.122783⟩ Article dans une revue hal-04501084v1
	The human OPA1 delTTAG mutation induces adult onset and progressive auditory neuropathy in mice Corentin Affortit , Carolanne Coyat , Anissa Rym Saidia , Jean-Charles Ceccato , Majida Charif Cellular and Molecular Life Sciences, 2024, 81, pp.80. ⟨10.1007/s00018-024-05115-4⟩ Article dans une revue hal-04501558v1
	Neuronal Blockade of Thyroid Hormone Signaling Increases Sensitivity to Diet-Induced Obesity in Adult Male Mice Eva Rial-Pensado , Laurence Canaple , Romain Guyot , Christoffer Clemmensen , Joëlle Wiersema Endocrinology, 2023, 164 (4), pp.bqad034. ⟨10.1210/endocr/bqad034⟩ Article dans une revue hal-04041371v1
	Thyroid hormone action during GABAergic neuron maturation: The quest for mechanisms Sabine Richard , Juan Ren , Frederic Flamant Frontiers in Endocrinology, 2023, 14, ⟨10.3389/fendo.2023.1256877⟩ Article dans une revue hal-04230619v1
	Thyroid hormone as a temporal switch in mouse development Juan Ren , Frederic Flamant European Thyroid Journal , 2023, 12 (2), pp.e220225. ⟨10.1530/etj-22-0225⟩ Article dans une revue hal-04222418v1
	Is periventricular heterotopia a useful endpoint for developmental thyroid hormone system disruption in mouse toxicity studies? Louise Ramhøj , Romain Guyot , Terje Svingen , Andreas Kortenkamp , Frederic Flamant Regulatory Toxicology and Pharmacology, 2023, 142, pp.105445. ⟨10.1016/j.yrtph.2023.105445⟩ Article dans une revue hal-04222380v1
	A disease-associated mutation in thyroid hormone receptor α1 causes hearing loss and sensory hair cell patterning defects in mice Corentin Affortit , Fabian Blanc , Jamal Nasr , Jean-Charles Ceccato , Suzy Markossian Science Signaling, 2022, 15 (738), ⟨10.1126/scisignal.abj4583⟩ Article dans une revue hal-03746401v1
	Prenatal exposure to paraquat and nanoscaled TiO2 aerosols alters the gene expression of the developing brain Quentin Hamdaoui , Yanis Zekri , Sabine Richard , Denise Aubert , Romain Guyot Chemosphere, 2022, 287 (Pt 3), pp.132253. ⟨10.1016/j.chemosphere.2021.132253⟩ Article dans une revue hal-03403617v1
	An Atlas of Thyroid Hormone Receptors’ Target Genes in Mouse Tissues Yanis Zekri , Romain Guyot , Frederic Flamant International Journal of Molecular Sciences, 2022, 23 (19), pp.11444. ⟨10.3390/ijms231911444⟩ Article dans une revue hal-03885312v1
	Brown adipocytes local response to thyroid hormone is required for adaptive thermogenesis in adult male mice Yanis Zekri , Romain Guyot , Inés Garteizgogeascoa Suñer , Laurence Canaple , Amandine Gautier Stein eLife, 2022, 11, pp.e81996. ⟨10.7554/elife.81996⟩ Article dans une revue hal-03958312v1
	A CRISPR/Cas9-engineered avatar mouse model of monocarboxylate transporter 8 deficiency displays distinct neurological alterations Víctor Valcárcel-Hernández , Marina Guillén-Yunta , Miranda Bueno-Arribas , Ana Montero-Pedrazuela , Carmen Grijota-Martínez Neurobiology of Disease, 2022, 174, pp.105896. ⟨10.1016/j.nbd.2022.105896⟩ Article dans une revue hal-03887086v1
	Functional Definition of Thyroid Hormone Response Elements Based on a Synthetic STARR-seq Screen Frédéric Flamant , Yanis Zekri , Romain Guyot Endocrinology, 2022, 163 (8), pp.bqac084. ⟨10.1210/endocr/bqac084⟩ Article dans une revue hal-03746531v1
	In vitro assessment of pesticides capacity to act as agonists/antagonists of the thyroid hormone nuclear receptors Yanis Zekri , Laure Dall Agnol , Frederic Flamant , Romain Guyot iScience, 2021, 24 (9), pp.1-21. ⟨10.1016/j.isci.2021.102957⟩ Article dans une revue hal-03520452v1
	Metrological Characterization of an Aerosol Exposure Chamber to Explore the Inhalation Effects of the Combination of Paraquat and TiO2 Nano-objects Quentin Hamdaoui , A. Bencsik , Frederic Flamant , Simon Delcour , Tatiana Macé Aerosol and Air Quality Research, 2021, 21 (8), pp.200626. ⟨10.4209/aaqr.200626⟩ Article dans une revue hal-03416520v1
	Central vs. Peripheral Action of Thyroid Hormone in Adaptive Thermogenesis: A Burning Topic Yanis Zekri , Frederic Flamant , Karine Gauthier Cells, 2021, 10 (6), pp.1327. ⟨10.3390/cells10061327⟩ Article dans une revue hal-03278371v1
	Thyroid hormone and mammalian tissue regeneration Frederic Flamant Annales d'Endocrinologie, 2021, 82 (3-4), pp.158-160. ⟨10.1016/j.ando.2020.02.002⟩ Article dans une revue hal-03285023v1
	ERGO: Breaking Down the Wall between Human Health and Environmental Testing of Endocrine Disrupters Henrik Holbech , Peter Matthiessen , Martin Hansen , Gerrit Schuurmann , Dries Knapen International Journal of Molecular Sciences, 2020, 21 (8), pp.2954. ⟨10.3390/ijms21082954⟩ Article dans une revue hal-02904035v1
	Two Novel Cases of Resistance to Thyroid Hormone Due to THRA Mutation Albane Le Maire , Natacha Bouhours-Nouet , Jessica Soamalala , Delphine Mirebeau-Prunier , Matteo Paloni Thyroid, 2020, 30 (8), pp.1217-1221. ⟨10.1089/thy.2019.0602⟩ Article dans une revue hal-03042980v1
	Thyroid hormone receptor α in skeletal muscle is essential for T3‐mediated increase in energy expenditure Trine S Nicolaisen , Anders B Klein , Oksana Dmytriyeva , Jens Lund , Lars R Ingerslev FASEB Journal, 2020, 34 (11), pp.15480-15491. ⟨10.1096/fj.202001258RR⟩ Article dans une revue hal-02996920v1
	A Pivotal Genetic Program Controlled by Thyroid Hormone during the Maturation of GABAergic Neurons Sabine Richard , Romain Guyot , Martin Rey-Millet , Margaux Prieux , Suzy S. Markossian iScience, 2020, 23 (3), pp.100899. ⟨10.1016/j.isci.2020.100899⟩ Article dans une revue hal-03254963v1
	PRMT1 Is Critical for the Transcriptional Activity and the Stability of the Progesterone Receptor. Lucie Malbeteau , Coralie Poulard , Cécile Languilaire , Ivan Mikaelian , Frederic Flamant iScience, 2020, 23 (6), pp.101236. ⟨10.1016/j.isci.2020.101236⟩ Article dans une revue hal-03019840v1
	Metabolomic Profiling of Body Fluids in Mouse Models Demonstrates that Nuclear Magnetic Resonance Is a Putative Diagnostic Tool for the Presence of Thyroid Hormone Receptor α1 Mutations Houda Boumaza , Suzy S. Markossian , Baptiste Busi , Gilles J.P. Rautureau , Karine Gauthier Thyroid, 2019, 29 (9), pp.1327-1335. ⟨10.1089/thy.2018.0730⟩ Article dans une revue hal-02983685v1
	Evidence for hormonal control of heart regenerative capacity during endothermy acquisition Kentaro Hirose , Alexander Payumo , Stephen Cutie , Alison Hoang , Hao Zhang Science, 2019, pp.eaar2038. ⟨10.1126/science.aar2038⟩ Article dans une revue hal-02983719v1
	New Case of Thyroid Hormone Resistance α Caused by a Mutation of THRA/TRα1 Hui Sun , Haiying Wu , Rongrong Xie , Fengyun Wang , Ting Chen Journal of the Endocrine Society, 2019, 3 (3), pp.665-669. ⟨10.1210/js.2019-00011⟩ Article dans une revue hal-02983728v1
	Pesticides, perturbateurs endocriniens de la glande thyroïde ? Frederic Flamant Les cahiers de la Recherche : Santé, Environnement, Travail, 2019, Les perturbateurs endocriniens, 13, pp.23-25 Article dans une revue anses-02445614v1
	Electroporation of mice zygotes with dual guide RNA/Cas9 complexes for simple and efficient cloning-free genome editing Marie Teixeira , Bénédicte F. Py , Christophe Bosc , Daphné Laubreton , Marie-Jo Moutin Scientific Reports, 2018, 8 (1), pp.4679. ⟨10.1038/s41598-018-22724-9⟩ Article dans une revue hal-01908850v1
	Two Protocols to Study the Interactions of Thyroid Hormone Receptors with Other Proteins and Chromatin Henrik Holbech , Peter Matthiessen , Martin Hansen , Gerrit Schüürmann , Dries Knapen Frontiers in Endocrinology, 2018, 1801 (3), pp.9-16. ⟨10.1007/978-1-4939-7902-8_2⟩ Article dans une revue hal-03278376v1
	Electroporation of mice zygotes with dual guide RNA/Cas9 complexes for simple and efficient cloning-free genome editing Marie Teixeira , Bénédicte Py , Christophe Bosc , Daphne Laubreton , Marie-Jo Moutin Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-017-18826-5⟩ Article dans une revue hal-02345809v1
	CRISPR/Cas9 Editing of the Mouse Thra Gene Produces Models with Variable Resistance to Thyroid Hormone Suzy S. Markossian , Romain Guyot , Sabine Richard , Marie Teixeira , Nadine Aguilera Thyroid, 2018, 28 (1), pp.139-150. ⟨10.1089/thy.2017.0389⟩ Article dans une revue hal-03278383v1
	Regulation of T3 Availability in the Developing Brain: The Mouse Genetics Contribution Sabine Richard , Frederic Flamant Frontiers in Endocrinology, 2018, 9, 11 p. ⟨10.3389/fendo.2018.00265⟩ Article dans une revue hal-02621572v1
	Neuronal expression of a thyroid hormone receptor α mutation alters mouse behaviour S. Richard , N. Aguilera , M. Thévenet , O. Dkhissi-Benyahya , Frederic Flamant Behavioural Brain Research, 2017, 321, pp.18-27. ⟨10.1016/j.bbr.2016.12.025⟩ Article dans une revue hal-03278396v1
	Genetic Investigation of Thyroid Hormone Receptor Function in the Developing and Adult Brain Frederic Flamant , Karine Gauthier , Sabine Richard Current Topics in Developmental Biology, 2017, 125, pp.303-335. ⟨10.1016/bs.ctdb.2017.01.001⟩ Article dans une revue hal-03278392v1
	Thyroid Hormone Signaling Pathways: Time for a More Precise Nomenclature Frederic Flamant , Sheue-Yann Cheng , Anthony Hollenberg , Lars Moeller , Jacques Samarut Endocrinology, 2017, 158 (7), pp.2052-2057. ⟨10.1210/en.2017-00250⟩ Article dans une revue hal-03278395v1
	Methylcytosine dioxygenase TET3 interacts with thyroid hormone nuclear receptors and stabilizes their association to chromatin Wenyue Guan , Romain Guyot , Jacques Samarut , Frederic Flamant , Jiemin Wong Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (31), pp.8229-8234. ⟨10.1073/pnas.1702192114⟩ Article dans une revue hal-03278385v1
	CRISPR/Cas9: a breakthrough in generating mouse models for endocrinologists Suzy S. Markossian , Frederic Flamant Journal of Molecular Endocrinology, 2016, 57 (2), pp.R81-R92. ⟨10.1530/JME-15-0305⟩ Article dans une revue hal-03278399v1
	Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease Brian Finan , Christoffer Clemmensen , Zhimeng Zhu , Kerstin Stemmer , Karine Gauthier Cell, 2016, 167 (3), pp.843-857.e14. ⟨10.1016/j.cell.2016.09.014⟩ Article dans une revue hal-03278397v1
	Thyroid Hormone signaling in the mouse retina Patrick Arbogast , Frederic Flamant , Pierre Godement , Martin Glösmann , Leo Peichl PLoS ONE, 2016, 11 (12), 20 p. ⟨10.1371/journal.pone.0168003⟩ Article dans une revue hal-01602508v1
	Futures Challenges in Thyroid Hormone Signaling Research Frederic Flamant Frontiers in Endocrinology, 2016, 7, ⟨10.3389/fendo.2016.00058⟩ Article dans une revue hal-02635655v1
	A Novel Mutation in THRA Gene Associated With an Atypical Phenotype of Resistance to Thyroid Hormone Stéphanie Espiard , Frédérique Savagner , Frederic Flamant , Virginie Vlaeminck-Guillem , Romain Guyot Journal of Clinical Endocrinology and Metabolism, 2015, 100 (8), pp.2841-2848. ⟨10.1210/jc.2015-1120⟩ Article dans une revue hal-02952401v1
	A temporary compendium of thyroid hormone target genes in brain Fabrice Chatonnet , Frederic Flamant , Beatriz Morte Biochimica et Biophysica Acta - Gene Regulatory Mechanisms , 2015, 1849 (2), pp.122-129. ⟨10.1016/j.bbagrm.2014.05.023⟩ Article dans une revue hal-02164764v1
	Editorial: “Thyroid Hormone in Brain and Brain Cells” Frederic Flamant , Noriyuki Koibuchi , Juan Bernal Frontiers in Endocrinology, 2015, 6, pp.99. ⟨10.3389/fendo.2015.00099⟩ Article dans une revue hal-03278404v1
	TRα receptor mutations extend the spectrum of syndromes of reduced sensitivity to thyroid hormone Virginie Vlaeminck-Guillem , Stéphanie Espiard , Frederic Flamant , Jean-Louis Wémeau La Presse Médicale, 2015, 44 (11), pp.1103-1112. ⟨10.1016/j.lpm.2015.07.022⟩ Article dans une revue hal-03278401v1
	Minireview: Deciphering Direct and Indirect Influence of Thyroid Hormone With Mouse Genetics N. Aguilera , M. Thévenet , O. Dkhissi-Benyahya , Frédéric Picou , Teddy Fauquier Molecular Endocrinology, 2014, 28 (4), pp.429-441. ⟨10.1210/me.2013-1414⟩ Article dans une revue hal-03278418v1
	Autonomous functions of murine thyroid hormone receptor TRα and TRβ in cochlear hair cells Juliane Dettling , Christoph Franz , Ulrike Zimmermann , Sze Chim Lee , Andreas Bress Molecular and Cellular Endocrinology, 2014, 382 (1), pp.26-37. ⟨10.1016/j.mce.2013.08.025⟩ Article dans une revue hal-03278424v1
	Purkinje cells and Bergmann glia are primary targets of the TRα1 thyroid hormone receptor during mouse cerebellum postnatal development. Teddy Fauquier , Fabrice Chatonnet , Frédéric Picou , Sabine Richard , Nicolas Fossat Development (Cambridge, England), 2014, 141 (1), pp.166-75. ⟨10.1242/dev.103226⟩ Article dans une revue hal-00968730v1
	Nongenomic, TRβ-Dependent, Thyroid Hormone Response Gets Genetic Support Fabrice Chatonnet , Gabriel Livera , Betty Fumel , Sophie Fouchécourt , Karine Gauthier Endocrinology, 2014, 155 (9), pp.3206-3209. ⟨10.1210/en.2014-1597⟩ Article dans une revue hal-03278412v1
	Toxicogenomic analysis of the ability of brominated flame retardants TBBPA and BDE-209 to disrupt thyroid hormone signaling in neural cells Romain Guyot , Fabrice Chatonnet , Benjamin Gillet , Sandrine Hughes , Frederic Flamant Toxicology, 2014, 325, pp.125-132. ⟨10.1016/j.tox.2014.08.007⟩ Article dans une revue hal-03278405v1
	The Targeted Inactivation of TRβ Gene in Thyroid Follicular Cells Suggests a New Mechanism of Regulation of Thyroid Hormone Production Samia Selmi-Ruby , Lamia Bouazza , Maria-Jesus Obregon , Aude Conscience , Frederic Flamant Endocrinology, 2014, 155 (2), pp.635-646. ⟨10.1210/en.2013-1435⟩ Article dans une revue hal-03278422v1
	Chondrocytes Play a Major Role in the Stimulation of Bone Growth by Thyroid Hormone Clémence Desjardin , Cyril Charles , Catherine Benoist-Lasselin , Julie Riviere , Maïlys Gilles Endocrinology, 2014, 155 (8), pp.3123-3135. ⟨10.1210/en.2014-1109⟩ Article dans une revue hal-01193997v1
	Direct and indirect consequences on gene expression of a thyroid hormone receptor alpha 1 mutation restricted to Sertoli cells Fabrice Chatonnet , Gabriel Livera , Betty Fumel , Sophie Fouchécourt , Frederic Flamant Molecular Reproduction and Development, 2014, 81 (12), pp.1159 - 1166. ⟨10.1002/mrd.22437⟩ Article dans une revue hal-01130502v1
	Genome-wide analysis of thyroid hormone receptors shared and specific functions in neural cells Hasan Avci , Clement Lebrun , Rosine Wehrle , Mohamed Doulazmi , Marie-Pierre Morel Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (8), pp.E766-E775. ⟨10.1073/pnas.1210626110⟩ Article dans une revue hal-03278425v1
	[Thyroid hormone T3 triggers the developmental loss of axonal regenerative capacity] Hasan X. Avci , Frederic Flamant , Isabelle Dusart Médecine/Sciences, 2013, 29 (3), pp.245--247. ⟨10.1051/medsci/2013293005⟩ Article dans une revue hal-01543628v1
	Profound morphological and functional changes of rodent Purkinje cells between the first and the second postnatal weeks: a metamorphosis? Isabelle Dusart , Frederic Flamant Frontiers in Neuroanatomy, 2012, 6, pp.11. ⟨10.3389/fnana.2012.00011⟩ Article dans une revue hal-01543632v1
	Thyroid hormone limits postnatal Sertoli cell proliferation in vivo by activation of its alpha1 isoform receptor (TRalpha1) present in these cells and by regulation of Cdk4/JunD/c-myc mRNA levels in mice Betty Fumel , Marie-Justine Guerquin , Gabriel Livera , Christophe Staub , Michèle Magistrini Biology of Reproduction, 2012, 87 (1), pp.1-9. ⟨10.1095/biolreprod.111.098418⟩ Article dans une revue hal-01129659v1
	Genome-Wide Search Reveals the Existence of a Limited Number of Thyroid Hormone Receptor Alpha Target Genes in Cerebellar Neurons Fabrice Chatonnet , Romain Guyot , Frédéric Picou , Maria Bondesson , Frederic Flamant PLoS ONE, 2012, 7 (5), pp.e30703. ⟨10.1371/journal.pone.0030703⟩ Article dans une revue hal-02164760v1
	Thyroid hormone triggers the developmental loss of axonal regenerative capacity via thyroid hormone receptor alpha 1 and kruppel-like factor 9 in Purkinje cells Hasan X. Avci , Clement Lebrun , Rosine Wehrle , Mohamed Doulazmi , Fabrice Chatonnet Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (35), pp.14206-14211. ⟨10.1073/pnas.1119853109⟩ Article dans une revue hal-01545809v1
	Hormone thyroïdienne et développement du cervelet : effets directs ou indirects ? Fabrice Chatonnet , Teddy Fauquier , Frederic Picou , Romain Guyot , Frederic Flamant Annales d'Endocrinologie, 2011, 72 (2), pp.99-102. ⟨10.1016/j.ando.2011.03.012⟩ Article dans une revue hal-02164736v1
	Otx2 Gene Deletion in Adult Mouse Retina Induces Rapid RPE Dystrophy and Slow Photoreceptor Degeneration. Francis Béby , Michael Housset , Nicolas Fossat , Coralie Le Greneur , Frederic Flamant PLoS ONE, 2010, 5 (7), pp.e11673. ⟨10.1371/journal.pone.0011673⟩ Article dans une revue hal-00506174v1
	A combined approach identifies a limited number of new thyroid hormone target genes in post-natal mouse cerebellum. Laure Quignodon , Carmen Grijota-Martinez , Emmanuel Compe , Romain Guyot , Nathalie Allioli Journal of Molecular Endocrinology, 2007, 39 (1), pp.17-28. ⟨10.1677/JME-06-0054⟩ Article dans une revue hal-00206218v1
	Peripheral circulation of the prion infectious agent in transgenic mice expressing the ovine prion protein gene in neurons only C. Crozet , S. Lezmi , Frederic Flamant , J. Samarut , T. Baron Journal of Infectious Diseases, 2007, 195 (7), pp.997-1006. ⟨10.1086/512085⟩ Article dans une revue hal-00180826v1
	Modeling the role of mid-wavelength cones in circadian responses to light. Ouria Dkhissi-Benyahya , Claude Gronfier , Wena de Vanssay , Frederic Flamant , Howard M. Cooper Neuron, 2007, 53 (5), pp.677-87. ⟨10.1016/j.neuron.2007.02.005⟩ Article dans une revue inserm-00135926v1
	Thyroid hormone signaling is highly heterogeneous during pre- and postnatal brain development Laure Quignodon , C. Legrand , Nathalie Allioli , A. Guadano-Ferraz , Joaquin Bernal Journal of Molecular Endocrinology, 2004, 33, pp.467-476 Article dans une revue hal-02672363v1
	Both thyroid hormone receptor (TR)beta1 and TRbeta2 isoforms contribute to the regulation of hypothalamic Thyrotropin-releasing hormone S.M. Dupré , H. Guissouma , Frederic Flamant , I. Seugnet , T.S. Scanlan Endocrinology, 2004, 145 (5), pp.2337-2345. ⟨10.1210/en.2003-1209⟩ Article dans une revue hal-02675694v1
	Thyroid hormone receptor alpha is a molecular switch of cardiac function between fetal and postnatal life W. Mai , M.F. Janier , Nathalie Allioli , Laure Quignodon , T. Chuzel Proceedings of the National Academy of Sciences of the United States of America, 2004, 101 (28), pp.10332-10337 Article dans une revue hal-02677765v1
	The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification E. Bonnafe , M. Touka , A. Aitlounis , D. Baas , E. Barras Molecular and Cellular Biology, 2004, 24 (10), pp.4417-4427 Article dans une revue hal-02679672v1
	Thyroid hormone receptors : lessons from knockout and knock-in mutant mice Frederic Flamant , Jacques Samarut Trends in Endocrinology and Metabolism = Trends in Endocrinology & Metabolism , 2003, 14 (2), pp.85-90 Article dans une revue hal-02670632v1
	Microarray analysis of knockout mice identifies cyclin D2 as a possible mediator for the action of thyroid hormone during the postnatal development of the cerebellum A.L. Poguet , C. Legrand , Xu Ping Feng , P.M. Yen , P. Meltzer Developmental Biology, 2003, 254, pp.188-199 Article dans une revue hal-02671535v1
	Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice P.M. Yen , Xu Ping Feng , Frederic Flamant , Y. Chen , R.L. Walker EMBO Reports, 2003, 4 (6), pp.581-587 Article dans une revue hal-02676180v1
	Persistence of oligodendrocyte precursor cells and altered myelination in optic nerve associated to retina degeneration in mice devoid of all thyroid hormone receptors D. Baas , C. Legrand , Jacques Samarut , Frederic Flamant Proceedings of the National Academy of Sciences of the United States of America, 2002, 99 (5), pp.2907-2911. ⟨10.1073/pnas.052482299⟩ Article dans une revue hal-02678333v1
	Congenital hypothyroid Pax8-/- mutant mice can be rescued by inactivating the TRalpha gene Frederic Flamant , A.L. Poguet , Michelina Plateroti , O. Chanssade , K. Gauthier Molecular Endocrinology -Baltimore-, 2002, 16 (1), pp.24-32 Article dans une revue hal-02679582v1
	Null mutant mice for thyroid hormone receptors. In Thyroid hormone receptors. Karine Gauthier , Denise Aubert , Olivier Chassande , Frederic Flamant , Jacques Samarut Methods in molecular medicine, 2002, 22, pp.13-29 Article dans une revue hal-00023831v1
	Florid Plaque in ovine PrP transgenic mice infected with an experimental ovine BSE. C. Crozet , A. Bencsik , Frederic Flamant , S. Lezmi , Jacques Samarut EMBO Reports, 2001, 21 (10), pp.952-956. ⟨10.1093/embo-reports/kve204⟩ Article dans une revue hal-00023828v1
	Efficient transmission of two different sheep scrapie isolates in transgenic mice expressing the ovine PrP gene Carole Crozet , Frederic Flamant , A. Bencsik , Denise Aubert , Jacques Samarut Journal of Virology, 2001, 75 (11), pp.5328-5334 Article dans une revue hal-02672143v1
	A novel growth -factor-dependent myeloid cell line derived from mouse bone marrow cells contains progenitors endowed with high proliferative potential V. Revol , I. Tsuboi , Frederic Flamant , Jacques Samarut , J.P. Blanchet Experimental Hematology, 1999, 27 (1), pp.88-98 Article dans une revue hal-02683916v1
	Eukaryotic conditional expression system T. Sourisseau , Y. Le Dréan , G. Salbert , Frederic Flamant , D. Michel Biotechniques, 1999, 27, pp.106-110 Article dans une revue hal-02688895v1
	Thyroid hormone receptor knockouts : their contribution to our understanding of thyroid hormone resistance Olivier Chassande , Frederic Flamant , Jacques Samarut Current Opinion in Endocrinology and Diabetes, 1999, 6, pp.293-300 Article dans une revue hal-02693744v1
	Involvement of thyroid hormone and its alpha receptor in avian neurulation Frederic Flamant , Jacques Samarut Developmental Biology, 1998, 197, pp.1-11 Article dans une revue hal-02683768v1
	Identification of transcripts initiated from an internal promoter in the c-erbA-alpha locus that encode inhibitors of retinoic acid receptor-alpha and triiodothyronine receptor activities Olivier Chassande , A. Fraichard , K. Gauthier , Frederic Flamant , C. Legrand Molecular Endocrinology -Baltimore-, 1997, 11 (9), pp.1278-1290 Article dans une revue hal-02695326v1
	The osteoclast generation : an in vitro and in vivo study with a genetically labelled avian monocytic cell line F. Solari , Frederic Flamant , Yan Cherel , Monique Wyers , Pierre Jurdic Journal of Cell Science, 1996, 109, pp.1203-1213 Article dans une revue hal-02691819v1
	Virofection : a one-step procedure for using replication-defective retrovirus vectors Frederic Flamant , Jacques Samarut Virology, 1995, 211, pp.234-240 Article dans une revue hal-02705128v1
	Vectors derived from avian leucosis and sarcoma viruses Frederic Flamant , Cosset François-Loïc , Jacques Samarut Journal of Molecular Medicine, 1995, 73, pp.181-187 Article dans une revue hal-02704566v1
	Replication-competent and -defective retrovirus vectors for oncogenic studies Jacques Samarut , Frederic Flamant , J.M. Heard Methods in Enzymology, 1995, 254, pp.206-228 Article dans une revue hal-02706921v1
	Virofection: a new procedure to achieve stable expression of genes transferred into early embryos Frederic Flamant , Barbara Demeneix , C. Benoist , Suzy Markossian-Belin , Jacques Samarut International Journal of Developmental Biology, 1994, 38, pp.751-757 Article dans une revue hal-02699936v1
	Use of helper cells with two host ranges to generate high-titer retroviral vectors Cosset François-Loïc , A. Girod , Frederic Flamant , A. Drynda , C. Ronfort Virology, 1993, 193, pp.385-395 Article dans une revue hal-02703909v1
	Importance of 3' non-coding sequences for efficient retrovirus-mediated gene transfer in avian cells revealed by self-inactivating vectors Frederic Flamant , Denise Aubert , C. Legrand , Cosset François-Loïc , Jacques Samarut Journal of General Virology, 1993, 74, pp.39-46 Article dans une revue hal-02699527v1
	Packaging cells for avian leukosis virus-based vectors with various host ranges Cosset François-Loïc , C. Ronfort , R.M. Molina , Frederic Flamant , A. Drynda Journal of Virology, 1992, 66 (9), pp.5671-5676 Article dans une revue hal-02703488v1
	Identifying genes involved in the variability of genetic fatness in the growing chicken M. Douaire , N. Le Fur , C. El Khadir-Mounier , Paul Langlois , Frederic Flamant Poultry Science, 1992, 71, pp.1911-1920 Article dans une revue hal-02699766v1
	Self-inactivating avian leukosis derived retroviral vectors for gene transfer and stable expression into cultured avian cells Denise Aubert , Camille Bagnis , Frederic Flamant , M. Garcia , Jacques Samarut Virology, 1991, 10, pp.71-76 Article dans une revue hal-02708464v1
	ApoVLDLII gene transcription in immature cockerels without estradiol stimulation. M. Douaire , Paul Langlois , Frederic Flamant , J. Mallard Comparative Biochemistry and Physiology, 1990, 97B (1), pp.55-57 Article dans une revue hal-02699564v1
	CONSTRUCTION ET UTILISATION DE VECTEURS DÉRIVÉS DU VIRUS DE L'ÉRYTHROBLASTOSE AVIAIRE POUR LE TRANSFERT DE GÈNES CHEZ LE POULET Frederic Flamant , Benchaibi M , Thoraval P , Chambonnet F , Savatier P Annales de Recherches Vétérinaires, 1988, 19 (1), pp.85-86 Article dans une revue hal-00901808v1
	In vitro synthesis of infectious retroviral RNA Frederic Flamant , J Sorge Journal of Virology, 1988, 62 (5), pp.1827-1831. ⟨10.1128/JVI.62.5.1827-1831.1988⟩ Article dans une revue hal-03278437v1
	Tissue specificity of retrovirus expression in inoculated avian embryos revealed by in situ hybridization to whole-body section. Frederic Flamant , D. Leguellec , Ghislain Verdier , Vm Nigon Virology, 1987, 160, pp.301-304 Article dans une revue hal-00314242v1
	An embryonic DNA-binding protein specific for the promoter of the retrovirus long terminal repeat Frederic Flamant , C Gurin , J Sorge Molecular and Cellular Biology, 1987, 7 (10), pp.3548-3553. ⟨10.1128/mcb.7.10.3548-3553.1987⟩ Article dans une revue hal-03278438v1

	Using mouse genetics to investigate thyroid hormone signaling in the developing and adult brain. Fabrice Chatonnet , Sabine Richard , Frederic Flamant Koibuchi N.; Yen P. Thyroid Hormone Disruption and Neurodevelopment, Springer Science+Business Media, 2016, Contemporary Clinical Neuroscience, ⟨10.1007/978-1-4939-3737-0_8⟩ Chapitre d'ouvrage hal-04231078v1

	A point mutation in the AF-2 domain of thyroid hormone receptor alpha1 expressed after CRE mediated recombination partially recapitulates hypothyroidism. Laure Quignodon , Séverine Vincent , Harald Winter , Jacques Samarut , Frederic Flamant 2007 Pré-publication, Document de travail ensl-00159617v1

Frédéric Flamant

Publications

Effect of in utero and lactational exposure to a thyroid hormone system disrupting chemical on mouse metabolome and brain transcriptome

The human OPA1 delTTAG mutation induces adult onset and progressive auditory neuropathy in mice

Neuronal Blockade of Thyroid Hormone Signaling Increases Sensitivity to Diet-Induced Obesity in Adult Male Mice

Thyroid hormone action during GABAergic neuron maturation: The quest for mechanisms

Thyroid hormone as a temporal switch in mouse development

Is periventricular heterotopia a useful endpoint for developmental thyroid hormone system disruption in mouse toxicity studies?

A disease-associated mutation in thyroid hormone receptor α1 causes hearing loss and sensory hair cell patterning defects in mice

Prenatal exposure to paraquat and nanoscaled TiO2 aerosols alters the gene expression of the developing brain

An Atlas of Thyroid Hormone Receptors’ Target Genes in Mouse Tissues

Brown adipocytes local response to thyroid hormone is required for adaptive thermogenesis in adult male mice

A CRISPR/Cas9-engineered avatar mouse model of monocarboxylate transporter 8 deficiency displays distinct neurological alterations

Functional Definition of Thyroid Hormone Response Elements Based on a Synthetic STARR-seq Screen

In vitro assessment of pesticides capacity to act as agonists/antagonists of the thyroid hormone nuclear receptors

Metrological Characterization of an Aerosol Exposure Chamber to Explore the Inhalation Effects of the Combination of Paraquat and TiO2 Nano-objects

Central vs. Peripheral Action of Thyroid Hormone in Adaptive Thermogenesis: A Burning Topic

Thyroid hormone and mammalian tissue regeneration

ERGO: Breaking Down the Wall between Human Health and Environmental Testing of Endocrine Disrupters

Two Novel Cases of Resistance to Thyroid Hormone Due to THRA Mutation

Thyroid hormone receptor α in skeletal muscle is essential for T3‐mediated increase in energy expenditure

A Pivotal Genetic Program Controlled by Thyroid Hormone during the Maturation of GABAergic Neurons

PRMT1 Is Critical for the Transcriptional Activity and the Stability of the Progesterone Receptor.

Metabolomic Profiling of Body Fluids in Mouse Models Demonstrates that Nuclear Magnetic Resonance Is a Putative Diagnostic Tool for the Presence of Thyroid Hormone Receptor α1 Mutations

Evidence for hormonal control of heart regenerative capacity during endothermy acquisition

New Case of Thyroid Hormone Resistance α Caused by a Mutation of THRA/TRα1

Pesticides, perturbateurs endocriniens de la glande thyroïde ?

Electroporation of mice zygotes with dual guide RNA/Cas9 complexes for simple and efficient cloning-free genome editing

Two Protocols to Study the Interactions of Thyroid Hormone Receptors with Other Proteins and Chromatin

Electroporation of mice zygotes with dual guide RNA/Cas9 complexes for simple and efficient cloning-free genome editing

CRISPR/Cas9 Editing of the Mouse Thra Gene Produces Models with Variable Resistance to Thyroid Hormone

Regulation of T3 Availability in the Developing Brain: The Mouse Genetics Contribution

Neuronal expression of a thyroid hormone receptor α mutation alters mouse behaviour

Genetic Investigation of Thyroid Hormone Receptor Function in the Developing and Adult Brain

Thyroid Hormone Signaling Pathways: Time for a More Precise Nomenclature

Methylcytosine dioxygenase TET3 interacts with thyroid hormone nuclear receptors and stabilizes their association to chromatin

CRISPR/Cas9: a breakthrough in generating mouse models for endocrinologists

Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease

Thyroid Hormone signaling in the mouse retina

Futures Challenges in Thyroid Hormone Signaling Research

A Novel Mutation in THRA Gene Associated With an Atypical Phenotype of Resistance to Thyroid Hormone

A temporary compendium of thyroid hormone target genes in brain

Editorial: “Thyroid Hormone in Brain and Brain Cells”

TRα receptor mutations extend the spectrum of syndromes of reduced sensitivity to thyroid hormone

Minireview: Deciphering Direct and Indirect Influence of Thyroid Hormone With Mouse Genetics

Autonomous functions of murine thyroid hormone receptor TRα and TRβ in cochlear hair cells

Purkinje cells and Bergmann glia are primary targets of the TRα1 thyroid hormone receptor during mouse cerebellum postnatal development.

Nongenomic, TRβ-Dependent, Thyroid Hormone Response Gets Genetic Support

Toxicogenomic analysis of the ability of brominated flame retardants TBBPA and BDE-209 to disrupt thyroid hormone signaling in neural cells

The Targeted Inactivation of TRβ Gene in Thyroid Follicular Cells Suggests a New Mechanism of Regulation of Thyroid Hormone Production

Chondrocytes Play a Major Role in the Stimulation of Bone Growth by Thyroid Hormone

Direct and indirect consequences on gene expression of a thyroid hormone receptor alpha 1 mutation restricted to Sertoli cells

Genome-wide analysis of thyroid hormone receptors shared and specific functions in neural cells

[Thyroid hormone T3 triggers the developmental loss of axonal regenerative capacity]

Profound morphological and functional changes of rodent Purkinje cells between the first and the second postnatal weeks: a metamorphosis?

Thyroid hormone limits postnatal Sertoli cell proliferation in vivo by activation of its alpha1 isoform receptor (TRalpha1) present in these cells and by regulation of Cdk4/JunD/c-myc mRNA levels in mice

Genome-Wide Search Reveals the Existence of a Limited Number of Thyroid Hormone Receptor Alpha Target Genes in Cerebellar Neurons

Thyroid hormone triggers the developmental loss of axonal regenerative capacity via thyroid hormone receptor alpha 1 and kruppel-like factor 9 in Purkinje cells

Hormone thyroïdienne et développement du cervelet : effets directs ou indirects ?

Otx2 Gene Deletion in Adult Mouse Retina Induces Rapid RPE Dystrophy and Slow Photoreceptor Degeneration.

A combined approach identifies a limited number of new thyroid hormone target genes in post-natal mouse cerebellum.

Peripheral circulation of the prion infectious agent in transgenic mice expressing the ovine prion protein gene in neurons only

Modeling the role of mid-wavelength cones in circadian responses to light.

Thyroid hormone signaling is highly heterogeneous during pre- and postnatal brain development

Both thyroid hormone receptor (TR)beta1 and TRbeta2 isoforms contribute to the regulation of hypothalamic Thyrotropin-releasing hormone

Thyroid hormone receptor alpha is a molecular switch of cardiac function between fetal and postnatal life

The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification

Thyroid hormone receptors : lessons from knockout and knock-in mutant mice

Microarray analysis of knockout mice identifies cyclin D2 as a possible mediator for the action of thyroid hormone during the postnatal development of the cerebellum

Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice

Persistence of oligodendrocyte precursor cells and altered myelination in optic nerve associated to retina degeneration in mice devoid of all thyroid hormone receptors

Congenital hypothyroid Pax8-/- mutant mice can be rescued by inactivating the TRalpha gene

Null mutant mice for thyroid hormone receptors. In Thyroid hormone receptors.

Florid Plaque in ovine PrP transgenic mice infected with an experimental ovine BSE.

Efficient transmission of two different sheep scrapie isolates in transgenic mice expressing the ovine PrP gene

A novel growth -factor-dependent myeloid cell line derived from mouse bone marrow cells contains progenitors endowed with high proliferative potential

Eukaryotic conditional expression system

Thyroid hormone receptor knockouts : their contribution to our understanding of thyroid hormone resistance

Involvement of thyroid hormone and its alpha receptor in avian neurulation

Identification of transcripts initiated from an internal promoter in the c-erbA-alpha locus that encode inhibitors of retinoic acid receptor-alpha and triiodothyronine receptor activities