François SICHEL

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Présentation

Publications

	6-Polyaminosteroid Squalamine Analogues Display Antibacterial Activity against Resistant Pathogens Delphine Vergoz , Flore Nilly , Florie Desriac , Magalie Barreau , Antoine Géry International Journal of Molecular Sciences, 2023, 24 (10), pp.8568. ⟨10.3390/ijms24108568⟩ Article dans une revue hal-04161494v1
	Differential normal skin transcriptomic response in total body irradiated mice exposed to scattered versus scanned proton beams Alexandre Leduc , Samia Chaouni , Frédéric Pouzoulet , Ludovic de Marzi , Frédérique Megnin-Chanet Scientific Reports, 2021, 11 (1), pp.5876. ⟨10.1038/s41598-021-85394-0⟩ Article dans une revue hal-03169799v1
	Nitrogen Dioxide Inhalation Exposures Induce Cardiac Mitochondrial Reactive Oxygen Species Production, Impair Mitochondrial Function and Promote Coronary Endothelial Dysfunction Ahmed Karoui , Clément Crochemore , Najah Harouki , Cecile Corbiere , David Preterre International Journal of Environmental Research and Public Health, 2020, 17 (15), ⟨10.3390/ijerph17155526⟩ Article dans une revue hal-02928488v1
	Hadrontherapy Interactions in Molecular and Cellular Biology Juliette Thariat , Samuel Valable , Carine Laurent , Siamak Haghdoost , Elodie A. Pérès International Journal of Molecular Sciences, 2020, 21 (1), pp.133. ⟨10.3390/ijms21010133⟩ Article dans une revue hal-02429129v1
	Comparative study on gene expression profile in rat lung after repeated exposure to diesel and biodiesel exhausts upstream and downstream of a particle filter Valérie Lecureur , Christelle Monteil , Marie Jaguin , Fabrice Cazier , David Préterre Environmental Pollution, 2020, 266 (Part 2), pp.115264. ⟨10.1016/j.envpol.2020.115264⟩ Article dans une revue hal-02930031v1
	Biological Effects of Scattered Versus Scanned Proton Beams on Normal Tissues in Total Body Irradiated Mice: Survival, Genotoxicity, Oxidative Stress and Inflammation Samia Chaouni , Alexandre Leduc , Frédéric Pouzoulet , Ludovic de Marzi , Frédérique Megnin-Chanet Antioxidants , 2020, 9 (12), pp.1170. ⟨10.3390/antiox9121170⟩ Article dans une revue hal-04151956v1
	An integrated functional and transcriptomic analysis reveals that repeated exposure to diesel exhaust induces sustained mitochondrial and cardiac dysfunctions Ahmed Karoui , Clément Crochemore , Paul Mulder , David Preterre , Fabrice Cazier Environmental Pollution, 2019, 246, pp.518-526. ⟨10.1016/j.envpol.2018.12.049⟩ Article dans une revue hal-01978723v1
	Evaluation of Lung Cell Toxicity of Surfactants for Inhalation Route F Lindenberg , François Sichel , Mathilde Lechevrel , R Respaud , Guillaume Saint-Lorant Journal of Toxicology and Risk Assessment, 2019, 5 (1), pp.133. ⟨10.23937/2572-4061.1510022⟩ Article dans une revue hal-02448735v1
	Complications cardiaques de la radiothérapie mammaire Emmanuel Kammerer , Jennifer Le Guévelou , Sophie Jacob , Julien Geffrelot , Serge Danhier Bulletin du Cancer, 2019, 106 (4), pp.379-388. ⟨10.1016/j.bulcan.2019.01.020⟩ Article dans une revue hal-02160245v1
	Production of early and late nuclear DNA damage and extracellular 8- oxodG in normal human skin fibroblasts after carbon ion irradiation compared to X-rays Virginie Prevost , François Sichel , Ivannah Pottier , Alexandre Leduc , Stéphanie Lagadu Toxicology in Vitro, 2018, 52, pp.116-121. ⟨10.1016/j.tiv.2018.06.004⟩ Article dans une revue inserm-02181592v1
	Influence of aging in the modulation of epigenetic biomarkers of carcinogenesis after exposure to air pollution Bertrand Fougère , Yann Landkocz , Capucine Lepers , Perrine Martin , Lucie Armand Experimental Gerontology, 2018, 110, p.125-132. ⟨10.1016/j.exger.2018.05.018⟩ Article dans une revue hal-02025021v1
	Comparative study of diesel and biodiesel exhausts on lung oxidative stress and genotoxicity in rats Thierry Douki , Cécile Corbière , D. Preterre , Perrine Martin , V. Lecureur Environmental Pollution, 2018, 235, pp.514-524. ⟨10.1016/j.envpol.2017.12.077⟩ Article dans une revue hal-01711070v1
	Répartition du mollusque gastéropode nudibranche Dendrodoris limbata (Cuvier, 1804) le long des côtes métropolitaines françaises : apport de l’outil de sciences participatives BioObs François Sichel , Jean-Pierre Castillo , Pierre Noel , Alain Mayoux , Laurent Colombet Naturae, 2018, 5, pp.57-62. ⟨10.5852/naturae2018a5⟩ Article dans une revue hal-02492238v1
	Chemical characterization of fine and ultrafine PM, direct and indirect genotoxicity of PM and their organic extracts on pulmonary cells Sylvain Billet , Yann Landkocz , Perrine Martin , Anthony Verdin , Frédéric Ledoux Journal of Environmental Sciences, 2018, 71, pp.168-178. ⟨10.1016/j.jes.2018.04.022⟩ Article dans une revue hal-02025015v1
	Impact of after-treatment devices and biofuels on diesel exhausts genotoxicity in A549 cells exposed at air-liquid interface Claire Barraud , Cécile Corbière , I. Pottier , E. Estace , K. Blanchard Toxicology in Vitro, 2017, 45 (Part 3), pp.426-433. ⟨10.1016/j.tiv.2017.04.025⟩ Article dans une revue hal-02025402v1
	Résultats préliminaires de l’étude Paescart : prédiction de l’apparition d’effets secondaires cutanés tardifs après radiothérapie D. Lecomte Dumont , D. Stefan , F. Sichel , J.-L. Habrand , Carine Laurent Cancer/Radiothérapie, 2017, 21 (6-7), pp.712-713. ⟨10.1016/j.canrad.2017.08.077⟩ Article dans une revue hal-02479011v1
	Is hyperthermic intraperitoneal chemotherapy (HIPEC) safe for healthcare workers? Simon Rodier , Guillaume Saint-Lorant , Jean-Marc Guilloit , Agnès Palix , Fabienne Divanon Surgical Oncology, 2017, 26 (3), pp.242-251. ⟨10.1016/j.suronc.2017.04.001⟩ Article dans une revue hal-02025028v1
	Cytotoxicity and genotoxicity effects of arsenic trioxide on SQ20B human laryngeal carcinoma cells Fatma Trabelsi , Rim Khlifi , Didier Goux , Marilyne Guillamin , Amel Hamza-Chaffai Experimental and Toxicologic Pathology, 2017, 69 (6), pp.349-358. ⟨10.1016/j.etp.2017.02.003⟩ Article dans une revue hal-02160250v1
	Fine and ultrafine atmospheric particulate matter at a multi-influenced urban site: Physicochemical characterization, mutagenicity and cytotoxicity Yann Landkocz , Frédéric Ledoux , Véronique André , Fabrice Cazier , Paul Genevray Environmental Pollution, 2017, 221, pp.130-140. ⟨10.1016/j.envpol.2016.11.054⟩ Article dans une revue hal-02025255v1
	Genotoxic effects of cadmium in human head and neck cell line SQ20B Fatma Trabelsi , Rim Khlifi , Didier Goux , Marilyne Guillamin , Amel Hamza-Chaffai Environmental Science and Pollution Research, 2016, 23 (16), pp.16127-16136. ⟨10.1007/s11356-016-6772-4⟩ Article dans une revue hal-02025265v1
	Comparative mutagenicity and genotoxicity of particles and aerosols emitted by the combustion of standard vs. rapeseed methyl ester supplemented bio-diesel fuels V. Andre , Claire Barraud , David Capron , D. Preterre , V. Keravec Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2015, 777, pp.33-42. ⟨10.1016/j.mrgentox.2014.11.007⟩ Article dans une revue hal-02025276v1
	Mutagenicity and clastogenicity of native airborne particulate matter samples collected under industrial, urban or rural influence C. Lepers , M. Dergham , L. Armand , Sylvain Billet , A. Verdin Toxicology in Vitro, 2014, 28 (5), pp.866-874. ⟨10.1016/j.tiv.2014.03.011⟩ Article dans une revue hal-02186761v1
	Xenobiotic metabolism induction and bulky DNA adducts generated by particulate matter pollution in BEAS-2B cell line: geographical and seasonal influence Capucine Lepers , Veronique Andre , Mona Dergham , Sylvain Billet , Anthony Verdin Journal of Applied Toxicology, 2014, 34 (6), pp.703-713. ⟨10.1002/jat.2931⟩ Article dans une revue hal-02160269v1
	Polycyclic aromatic hydrocarbons within airborne particulate matter (PM 2.5 ) produced DNA bulky stable adducts in a human lung cell coculture model Imane Abbas , Guillaume Garçon , Françoise Saint-Georges , Veronique Andre , Pierre Gosset Journal of Applied Toxicology, 2013, 33 (2), pp.109-119. ⟨10.1002/jat.1722⟩ Article dans une revue hal-02186813v1
	Benzo[a]pyrene, Aflatoxine B1 and Acetaldehyde Mutational Patterns in TP53 Gene Using a Functional Assay: Relevance to Human Cancer Aetiology Vincent Paget , Mathilde Lechevrel , Veronique Andre , Jérémie Le Goff , Didier Pottier PLoS ONE, 2012, 7 (2), pp.e30921. ⟨10.1371/journal.pone.0030921⟩ Article dans une revue hal-02186767v1
	Mutagenicity and genotoxicity of PM2.5 issued from an urbano-industrialized area of Dunkerque (France) Véronique André , Sylvain Billet , D. Pottier , J. Le Goff , I. Pottier Journal of Applied Toxicology, 2011, 31 (2), pp.131-138. ⟨10.1002/jat.1572⟩ Article dans une revue hal-02186834v1
	Detection of extracellular 8-oxo-7,8-dihydro-2′-deoxyguanosine as a biomarker of oxidative damage in X-irradiated fibroblast cultures: optimization of analytical procedure Stéphanie Lagadu , Ivannah Pottier , François Sichel , Carine Laurent , Jean-Louis Lefaix Biomarkers, 2010, 15 (8), pp.707-714. ⟨10.3109/1354750X.2010.511269⟩ Article dans une revue hal-02297398v1
	8-oxo-7,8-dihydro-2'-deoxyguanosine as a biomarker of oxidative damage in oesophageal cancer patients: lack of association with antioxidant vitamins and polymorphism of hOGG1 and GST Stéphanie Lagadu , Mathilde Lechevrel , François Sichel , Jean Breton , Didier Pottier Journal of experimental & clinical cancer research, 2010, 29 (1), pp.157. ⟨10.1186/1756-9966-29-157⟩ Article dans une revue hal-02461268v1
	Benzene-induced mutational pattern in the tumour suppressor gene TP53 analysed by use of a functional assay, the functional analysis of separated alleles in yeast, in human lung cells Sylvain Billet , Vincent Paget , Guillaume Garçon , Natacha Heutte , Veronique Andre Archives of Toxicology, 2010, 84 (2), pp.99-107. ⟨10.1007/s00204-009-0478-z⟩ Article dans une revue hal-02186869v1
	Genotoxic potential of Polycyclic Aromatic Hydrocarbons-coated onto airborne Particulate Matter (PM2.5) in human lung epithelial A549 cells Sylvain Billet , Imane Abbas , Jérémie Le Goff , Anthony Verdin , Veronique Andre Cancer Letters, 2008, 270 (1), pp.144-155. ⟨10.1016/j.canlet.2008.04.044⟩ Article dans une revue hal-02186795v1

François SICHEL

Présentation

Publications

6-Polyaminosteroid Squalamine Analogues Display Antibacterial Activity against Resistant Pathogens

Differential normal skin transcriptomic response in total body irradiated mice exposed to scattered versus scanned proton beams

Nitrogen Dioxide Inhalation Exposures Induce Cardiac Mitochondrial Reactive Oxygen Species Production, Impair Mitochondrial Function and Promote Coronary Endothelial Dysfunction

Hadrontherapy Interactions in Molecular and Cellular Biology

Comparative study on gene expression profile in rat lung after repeated exposure to diesel and biodiesel exhausts upstream and downstream of a particle filter

Biological Effects of Scattered Versus Scanned Proton Beams on Normal Tissues in Total Body Irradiated Mice: Survival, Genotoxicity, Oxidative Stress and Inflammation

An integrated functional and transcriptomic analysis reveals that repeated exposure to diesel exhaust induces sustained mitochondrial and cardiac dysfunctions

Evaluation of Lung Cell Toxicity of Surfactants for Inhalation Route

Complications cardiaques de la radiothérapie mammaire

Production of early and late nuclear DNA damage and extracellular 8- oxodG in normal human skin fibroblasts after carbon ion irradiation compared to X-rays

Influence of aging in the modulation of epigenetic biomarkers of carcinogenesis after exposure to air pollution

Comparative study of diesel and biodiesel exhausts on lung oxidative stress and genotoxicity in rats

Répartition du mollusque gastéropode nudibranche Dendrodoris limbata (Cuvier, 1804) le long des côtes métropolitaines françaises : apport de l’outil de sciences participatives BioObs

Chemical characterization of fine and ultrafine PM, direct and indirect genotoxicity of PM and their organic extracts on pulmonary cells

Impact of after-treatment devices and biofuels on diesel exhausts genotoxicity in A549 cells exposed at air-liquid interface

Résultats préliminaires de l’étude Paescart : prédiction de l’apparition d’effets secondaires cutanés tardifs après radiothérapie

Is hyperthermic intraperitoneal chemotherapy (HIPEC) safe for healthcare workers?

Cytotoxicity and genotoxicity effects of arsenic trioxide on SQ20B human laryngeal carcinoma cells

Fine and ultrafine atmospheric particulate matter at a multi-influenced urban site: Physicochemical characterization, mutagenicity and cytotoxicity

Genotoxic effects of cadmium in human head and neck cell line SQ20B

Comparative mutagenicity and genotoxicity of particles and aerosols emitted by the combustion of standard vs. rapeseed methyl ester supplemented bio-diesel fuels

Mutagenicity and clastogenicity of native airborne particulate matter samples collected under industrial, urban or rural influence

Xenobiotic metabolism induction and bulky DNA adducts generated by particulate matter pollution in BEAS-2B cell line: geographical and seasonal influence

Polycyclic aromatic hydrocarbons within airborne particulate matter (PM 2.5 ) produced DNA bulky stable adducts in a human lung cell coculture model

Benzo[a]pyrene, Aflatoxine B1 and Acetaldehyde Mutational Patterns in TP53 Gene Using a Functional Assay: Relevance to Human Cancer Aetiology

Mutagenicity and genotoxicity of PM2.5 issued from an urbano-industrialized area of Dunkerque (France)

Detection of extracellular 8-oxo-7,8-dihydro-2′-deoxyguanosine as a biomarker of oxidative damage in X-irradiated fibroblast cultures: optimization of analytical procedure

8-oxo-7,8-dihydro-2'-deoxyguanosine as a biomarker of oxidative damage in oesophageal cancer patients: lack of association with antioxidant vitamins and polymorphism of hOGG1 and GST

Benzene-induced mutational pattern in the tumour suppressor gene TP53 analysed by use of a functional assay, the functional analysis of separated alleles in yeast, in human lung cells

Genotoxic potential of Polycyclic Aromatic Hydrocarbons-coated onto airborne Particulate Matter (PM2.5) in human lung epithelial A549 cells