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PBMC are as good a source of tumor-reactive T lymphocytes as TIL after selection by Melan-A/A2 multimer immunomagnetic sorting.
Nathalie Labarriere
,
Nadine Gervois
,
Annabelle Bonnin-Rivalland
,
Régis Bouquié
,
Francine Jotereau
,
et al.
Article dans une revue
istex
inserm-00167752v1
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Nouvelle stratégie vaccinale
François Lang
,
Catherine Rabu
France, N° de brevet: PCT/EP2019059421. 2019
Brevet
inserm-02537942v1
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MELOE-1 Antigen Contains Multiple HLA Class II T Cell Epitopes Recognized by Th1 CD4+ T Cells from Melanoma Patients
Mathilde Bobinet
,
Virginie Vignard
,
Anne Rogel
,
Amir Khammari
,
Brigitte Dréno
,
et al.
Article dans une revue
inserm-02481104v1
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Apoptotic Body-Loaded Dendritic Cells Efficiently Cross-Prime Cytotoxic T Lymphocytes Specific for NA17-A Antigen but Not for Melan-A/MART-1 Antigen
Nathalie Labarrière
,
Laurent Bretaudeau
,
Nadine Gervois
,
Marie Bodinier
,
Gwenola Bougras
,
et al.
Article dans une revue
inserm-02482082v1
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Synthesis and Evaluation of Disubstituted N1- and N3-Imidazolidin-2-ones Acting as Potential Immunosuppressive Agents
Caroline Sabourin
,
Jean-Michel Robert
,
Sylvie Robert-Piessard
,
Delphine Carbonnelle
,
François Lang
Article dans une revue
hal-02389888v1
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An additional ORF on meloe cDNA encodes a new melanoma antigen, MELOE-2, recognized by melanoma-speciWc T cells in the HLA-A2 context
Yann Godet
,
Agnès Moreau-Aubry
,
Dimitri Mompelat
,
Virginie Vignard
,
Amir Khammari
,
et al.
Article dans une revue
istex
inserm-02481965v1
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IRES-dependent translation of the long non coding RNA meloe in melanoma cells produces the most immunogenic MELOE antigens
Maud Charpentier
,
Mikael Croyal
,
Delphine Carbonnelle
,
Agnès Fortun
,
Laetitia Florenceau
,
et al.
Article dans une revue
inserm-01409602v1
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Production of recombinant human trimeric CD137L (4-1BBL). Cross-linking is essential to its T cell co-stimulation activity
Catherine Rabu
,
Agnès Quéméner
,
Yannick Jacques
,
Klara Echasserieau
,
Patricia Vusio
,
et al.
Article dans une revue
inserm-02442588v1
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A fast and efficient HLA multimer-based sorting procedure that induces little apoptosis to isolate clinical grade human tumor specific T lymphocytes
Régis Bouquié
,
Annabelle Bonnin
,
Karine Bernardeau
,
Amir Khammari
,
Brigitte Dréno
,
et al.
Article dans une revue
istex
inserm-02481983v1
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The Melanoma Antigens MELOE-1 and MELOE-2 Are Translated from a Bona Fide Polycistronic mRNA Containing Functional IRES Sequences
Delphine Carbonnelle
,
Virginie Vignard
,
Delphine Séhédic
,
Agnès Moreau-Aubry
,
Laetitia Florenceau
,
et al.
Article dans une revue
inserm-01726993v1
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Phase I/II clinical trial of adoptive cell transfer of sorted specific T cells for metastatic melanoma patients
Brigitte Dréno
,
Amir Khammari
,
Agnès Fortun
,
Virginie Vignard
,
Soraya Saiagh
,
et al.
Article dans une revue
inserm-03260784v1
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Adoptive Transfer of Tumor-Reactive Melan-A-Specific CTL Clones in Melanoma Patients Is Followed by Increased Frequencies of Additional Melan-A-Specific T Cells 1 The Journal of Immunology
Virginie Vignard
,
Brigitte Lemercier
,
Annick Lim
,
Marie-Christine Pandolfino
,
Yannick Guilloux
,
et al.
Article dans une revue
inserm-02482064v1
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hnRNP-A1 binds to the IRES of MELOE-1 antigen to promote its translation in stressed melanoma cells
Maud Charpentier
,
Emilie Dupré
,
Agnès Fortun
,
Floriane Briand
,
Mike Maillasson
,
et al.
Article dans une revue
hal-03334018v1
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TCR Analyses of Two Vast and Shared Melanoma Antigen-Specific T Cell Repertoires: Common and Specific Features
Sylvain Simon
,
Zhong Wu
,
J. Cruard
,
Virginie Vignard
,
Agnès Fortun
,
et al.
Article dans une revue
inserm-01885141v1
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A long peptide from MELOE-1 contains multiple HLA class II T cell epitopes in addition to the HLA-A*0201 epitope: an attractive candidate for melanoma vaccination
Anne Rogel
,
Virginie Vignard
,
Mathilde Bobinet
,
Nathalie Labarrière
,
Francois Lang
Article dans une revue
istex
inserm-02481956v1
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A Full GMP Process to Select and Amplify Epitope-Specific T Lymphocytes for Adoptive Immunotherapy of Metastatic Melanoma
Nathalie Labarrière
,
A Fortun
,
A Bellec
,
A. Khammari
,
B. Dreno
,
et al.
Article dans une revue
inserm-01727317v1
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Is antigen specificity the key to efficient adoptive T‑cell therapy?
Nathalie Labarrière
,
Amir A Khammari
,
François Lang
,
Brigitte Dreno
Article dans une revue
inserm-02481934v1
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Cancer vaccines: designing artificial synthetic long peptides to improve presentation of class I and class II T cell epitopes by dendritic cells
Catherine Rabu
,
Laurie Rangan
,
Laetitia Florenceau
,
Agnès Fortun
,
Maud Charpentier
,
et al.
Article dans une revue
inserm-01991877v1
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