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PBMC are as good a source of tumor-reactive T lymphocytes as TIL after selection by Melan-A/A2 multimer immunomagnetic sorting.

Nathalie Labarriere , Nadine Gervois , Annabelle Bonnin-Rivalland , Régis Bouquié , Francine Jotereau , et al.
Cancer Immunology, Immunotherapy, 2008, 57 (2), pp.185-95. ⟨10.1007/s00262-007-0361-9⟩
Article dans une revue istex inserm-00167752v1

Nouvelle stratégie vaccinale

François Lang , Catherine Rabu
France, N° de brevet: PCT/EP2019059421. 2019
Brevet inserm-02537942v1
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MELOE-1 Antigen Contains Multiple HLA Class II T Cell Epitopes Recognized by Th1 CD4+ T Cells from Melanoma Patients

Mathilde Bobinet , Virginie Vignard , Anne Rogel , Amir Khammari , Brigitte Dréno , et al.
PLoS ONE, 2012, 7 (12), pp.e51716. ⟨10.1371/journal.pone.0051716⟩
Article dans une revue inserm-02481104v1
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Apoptotic Body-Loaded Dendritic Cells Efficiently Cross-Prime Cytotoxic T Lymphocytes Specific for NA17-A Antigen but Not for Melan-A/MART-1 Antigen

Nathalie Labarrière , Laurent Bretaudeau , Nadine Gervois , Marie Bodinier , Gwenola Bougras , et al.
Cancer Immunology, Immunotherapy, 2002, 101 (3), pp.280-286. ⟨10.1002/ijc.10605⟩
Article dans une revue inserm-02482082v1

Synthesis and Evaluation of Disubstituted N1- and N3-Imidazolidin-2-ones Acting as Potential Immunosuppressive Agents

Caroline Sabourin , Jean-Michel Robert , Sylvie Robert-Piessard , Delphine Carbonnelle , François Lang
Journal of Enzyme Inhibition and Medicinal Chemistry, 2008, 19 (6), pp.459-465. ⟨10.1080/14756360412331280482⟩
Article dans une revue hal-02389888v1
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An additional ORF on meloe cDNA encodes a new melanoma antigen, MELOE-2, recognized by melanoma-speciWc T cells in the HLA-A2 context

Yann Godet , Agnès Moreau-Aubry , Dimitri Mompelat , Virginie Vignard , Amir Khammari , et al.
Cancer Immunology, Immunotherapy, 2010, 59 (3), pp.431 - 439. ⟨10.1007/s00262-009-0762-z⟩
Article dans une revue istex inserm-02481965v1
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IRES-dependent translation of the long non coding RNA meloe in melanoma cells produces the most immunogenic MELOE antigens

Maud Charpentier , Mikael Croyal , Delphine Carbonnelle , Agnès Fortun , Laetitia Florenceau , et al.
Oncotarget, 2016, 7 (37), pp.59704-59713. ⟨10.18632/oncotarget.10923⟩
Article dans une revue inserm-01409602v1
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Production of recombinant human trimeric CD137L (4-1BBL). Cross-linking is essential to its T cell co-stimulation activity

Catherine Rabu , Agnès Quéméner , Yannick Jacques , Klara Echasserieau , Patricia Vusio , et al.
Journal of Biological Chemistry, 2005, 280, pp.41472 - 41481. ⟨10.1074/jbc.M506881200⟩
Article dans une revue inserm-02442588v1
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A fast and efficient HLA multimer-based sorting procedure that induces little apoptosis to isolate clinical grade human tumor specific T lymphocytes

Régis Bouquié , Annabelle Bonnin , Karine Bernardeau , Amir Khammari , Brigitte Dréno , et al.
Cancer Immunology, Immunotherapy, 2008, 58 (4), pp.553-566. ⟨10.1007/s00262-008-0578-2⟩
Article dans une revue istex inserm-02481983v1
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The Melanoma Antigens MELOE-1 and MELOE-2 Are Translated from a Bona Fide Polycistronic mRNA Containing Functional IRES Sequences

Delphine Carbonnelle , Virginie Vignard , Delphine Séhédic , Agnès Moreau-Aubry , Laetitia Florenceau , et al.
PLoS ONE, 2013, 8 (9), pp.e75233. ⟨10.1371/journal.pone.0075233⟩
Article dans une revue inserm-01726993v1
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Phase I/II clinical trial of adoptive cell transfer of sorted specific T cells for metastatic melanoma patients

Brigitte Dréno , Amir Khammari , Agnès Fortun , Virginie Vignard , Soraya Saiagh , et al.
Cancer Immunology, Immunotherapy, 2021, Online ahead of print. ⟨10.1007/s00262-021-02961-0⟩
Article dans une revue inserm-03260784v1
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Adoptive Transfer of Tumor-Reactive Melan-A-Specific CTL Clones in Melanoma Patients Is Followed by Increased Frequencies of Additional Melan-A-Specific T Cells 1 The Journal of Immunology

Virginie Vignard , Brigitte Lemercier , Annick Lim , Marie-Christine Pandolfino , Yannick Guilloux , et al.
Journal of Immunology, 2005, 175 (7), pp.4797-4805. ⟨10.4049/jimmunol.175.7.4797⟩
Article dans une revue inserm-02482064v1

hnRNP-A1 binds to the IRES of MELOE-1 antigen to promote its translation in stressed melanoma cells

Maud Charpentier , Emilie Dupré , Agnès Fortun , Floriane Briand , Mike Maillasson , et al.
Molecular Oncology, 2022, 16 (3), pp.594-606. ⟨10.1002/1878-0261.13088⟩
Article dans une revue hal-03334018v1
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TCR Analyses of Two Vast and Shared Melanoma Antigen-Specific T Cell Repertoires: Common and Specific Features

Sylvain Simon , Zhong Wu , J. Cruard , Virginie Vignard , Agnès Fortun , et al.
Frontiers in Immunology, 2018, 9, pp.1962. ⟨10.3389/fimmu.2018.01962⟩
Article dans une revue inserm-01885141v1
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A long peptide from MELOE-1 contains multiple HLA class II T cell epitopes in addition to the HLA-A*0201 epitope: an attractive candidate for melanoma vaccination

Anne Rogel , Virginie Vignard , Mathilde Bobinet , Nathalie Labarrière , Francois Lang
Cancer Immunology, Immunotherapy, 2011, 60 (3), pp.327-337. ⟨10.1007/s00262-010-0938-6⟩
Article dans une revue istex inserm-02481956v1
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A Full GMP Process to Select and Amplify Epitope-Specific T Lymphocytes for Adoptive Immunotherapy of Metastatic Melanoma

Nathalie Labarrière , A Fortun , A Bellec , A. Khammari , B. Dreno , et al.
Clinical and Developmental Immunology, 2013, 2013, pp.1 - 11. ⟨10.1155/2013/932318⟩
Article dans une revue inserm-01727317v1
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Is antigen specificity the key to efficient adoptive T‑cell therapy?

Nathalie Labarrière , Amir A Khammari , François Lang , Brigitte Dreno
Immunotherapy, 2011, ⟨10.2217/IMT.11.16⟩
Article dans une revue inserm-02481934v1
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Cancer vaccines: designing artificial synthetic long peptides to improve presentation of class I and class II T cell epitopes by dendritic cells

Catherine Rabu , Laurie Rangan , Laetitia Florenceau , Agnès Fortun , Maud Charpentier , et al.
OncoImmunology, 2019, pp.e1560919-2. ⟨10.1080/2162402x.2018.1560919⟩
Article dans une revue inserm-01991877v1