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Tumor Immunotargeting Using Innovative Radionuclides

Françoise Kraeber-Bodéré , Caroline Rousseau , Caroline Bodet-Milin , Cédric Mathieu , François Guérard , et al.
International Journal of Molecular Sciences, 2015, 16 (2), pp.3932 - 3954. ⟨10.3390/ijms16023932⟩
Article dans une revue inserm-01818715v1
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Advances in the chemistry of astatine and implications for the development of radiopharmaceuticals

François Guérard , Clémence Maingueneau , Lu Liu , Romain Eychenne , Jean-François Gestin , et al.
Accounts of Chemical Research, 2021, 54 (16), pp.3264. ⟨10.1021/acs.accounts.1c00327⟩
Article dans une revue inserm-03290202v1
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Production of [211 At]-Astatinated Radiopharmaceuticals and Applications in Targeted alpha-Particle Therapy

François Guérard , Jean-François Gestin , Martin W Brechbiel
Cancer Biotherapy and Radiopharmaceuticals, 2013, 28 (1), pp.1-20. ⟨10.1089/cbr.2012.1292⟩
Article dans une revue inserm-02496646v1

Method for Radioiodination or Radioastatination of a biomolecule

Marion Berdal , François Guérard , Jean-François Gestin , Alain Faivre-Chauvet
France, Patent n° : WO 2020/221744 A1. 2020
Brevet inserm-03013584v1
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Advances in the Radiolabeling of Antibodies with Astatine-211 : Toward Simplified Procedures and Improved Radiochemical Yields

François Guérard , Laurent Navarro , Marion Berdal , Ferid Haddad , Michel Chérel , et al.
TAT 11 INTERNATIONAL SYMPOSIUM, Apr 2019, OTTAWA, Canada. pp.S29
Communication dans un congrès inserm-02340810v1
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Efficacy of Astatine-211 radioimmunotherapy of Multiple Myeloma using an anti-mCD138 monoclonal antibody in a syngeneic murine model

Sébastien Gouard , Benjamin Chalopin , Catherine Saï-Maurel , François Guérard , Laurent Navarro , et al.
European Journal of Nuclear Medicine and Molecular Imaging, 2018, 45 (1), pp.S166-S167
Article dans une revue inserm-02341491v1
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Prospects for Enhancing Efficacy of Radioimmunotherapy

Clément Bailly , Caroline Bodet-Milin , François Guérard , Caroline Rousseau , Michel Chérel , et al.
Resistance to Ibritumomab in Lymphoma, pp.139-153, 2018, ⟨10.1007/978-3-319-78238-6_10⟩
Chapitre d'ouvrage inserm-02315459v1
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Cell Tracking in Cancer Immunotherapy

Justine Perrin , Marisa Capitao , Marie Mougin-Degraef , François Guérard , Alain Faivre-Chauvet , et al.
Frontiers in Medicine, 2020, 7, pp.34. ⟨10.3389/fmed.2020.00034⟩
Article dans une revue inserm-02512946v1

Method for Radioioidination OR Radioastatination of a Biomolecule

Marion Berdal , Alain Faivre-Chauvet , Jean-François Gestin , François Guérard
France, Patent n° : 19305563.9 - 1 109. 2019
Brevet inserm-02547459v1
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Bifunctional aryliodonium salts for highly efficient radioiodination and astatination of antibodies

François Guérard , Laurent Navarro , Y.-S. Lee , Aurélia Roumesy , Cyrille Alliot , et al.
Bioorganic and Medicinal Chemistry, 2017, Epub ahead of print. ⟨10.1016/j.bmc.2017.09.022⟩
Article dans une revue inserm-01592684v1
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P-169 - Influence of radiolysis on astatine-211 chemistry

Mohammad Ghalei , Parastoo Mahdi Khoshouei , Johan Vandenborre , François Guérard , Guillaume Blain , et al.
International symposium of radiopharmaceutical sciences, May 2022, Nantes, France
Communication dans un congrès inserm-03821660v1
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Investigation of the complexation of nat Zr(IV) and 89 Zr(IV) by hydroxypyridinones for the development of chelators for PET imaging applications

François Guérard , Maryline Beyler , Y.-S Lee , Raphaël Tripier , Jean-François Gestin , et al.
Dalton Transactions, 2017, 46, pp.4749-4758. ⟨10.1039/c6dt04625h⟩
Article dans une revue inserm-01496515v1
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Feasibility of the radioastatination of a monoclonal antibody with astatine-211 purified by wet extraction

Mickaël Bourgeois , François Guérard , Cyrille Alliot , Marie Mougin-Degraef , Holisoa Rajerison , et al.
Journal of Labelled Compounds and Radiopharmaceuticals, 2008, 51 (11), pp.379 - 383. ⟨10.1002/jlcr.1543⟩
Article dans une revue istex inserm-03290253v1
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L’astate-211 pour la radiothérapie vectorisée des cancers

François Guérard
L'Actualité Chimique, 2017, 52, pp.143-144
Article dans une revue inserm-01628339v1
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P-230 - Aryliodonium ylides as efficient precursors for astatine-211 labeling

Clémence Maingueneau , Marion Berdal , Romain Eychenne , Joëlle Gaschet , Michel Chérel , et al.
International symposium of radiopharmaceutical sciences, May 2022, Nantes, France
Communication dans un congrès inserm-03842392v1

Investigation of Zr( iv ) and 89 Zr( iv ) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging

François Guérard , Yong-Sok Lee , Raphaël Tripier , Lawrence P. Szajek , Jeffrey R. Deschamps , et al.
Chemical Communications, 2013, 49 (10), pp.1002 - 1004. ⟨10.1039/C2CC37549D⟩
Article dans une revue hal-01555852v1
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Synthesis of precursors for 211At-labelling of anti-PSMA HuJ591 mAb and stability comparison after in vitro cellular internalization

Aurélia Roumesy , Sebastien Gouard , Laurent Navarro , Faustine Lelan , Ferid Haddad , et al.
ISRS 2019, May 2019, PEKIN, China. pp.S69-S70
Communication dans un congrès inserm-02340836v1
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Radiolabeling Chemistry with Heavy Halogens Iodine and Astatine

Romain Eychenne , Cyrille Alliot , Jean-François Gestin , François Guérard
Biomedical Sciences, Online ahead of print, 2021
Chapitre d'ouvrage inserm-03332003v1
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Radioimmunotherapy of Lymphomas

Clément Bailly , Caroline M Bodet-Milin , François Guérard , Nicolas Chouin , Joëlle Gaschet , et al.
Nuclear Medicine Therapy, 2019, ⟨10.1007/978-3-030-17494-1_8⟩
Chapitre d'ouvrage inserm-02309716v1

Which radionuclide, carrier molecule and clinical indication for alpha-immunotherapy?

François Guérard , Jacques Barbet , Ferid Haddad , Michel Cherel , Francoise Kraeber-Bodere , et al.
The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutic, 2015
Article dans une revue hal-02415080v1
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Direct nucleophilic radioiodination and astatination of antibodies via pre-conjugated arylboronic acids

Marion Berdal , Laurent Navarro , Cyrille Alliot , Michel Chérel , Alain Faivre-Chauvet , et al.
Journal of Labelled Compounds and Radiopharmaceuticals, 2019
Article dans une revue inserm-02340736v1
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Targeted alpha-therapy with 211At-anti-mCD138 mAb in a syngeneic murine Multiple Myeloma model : can repeated doses or fractionation protocol overpass single dose efficiency?

Sébastien Gouard , Séverine Marionneau-Lambot , Joëlle Gaschet , Sébastien Chouin , F. Haddad , et al.
33rd Annual Congress of the European-Association-of-Nuclear-Medicine (EANM), European-Association-of-Nuclear-Medicine (EANM), Oct 2020, Virtuel, France. pp.S410-S411, ⟨10.1158/1078-0432.CCR-18-⟩
Communication dans un congrès inserm-03500243v1
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Radioimmunoconjugates for treating cancer: recent advances and current opportunities

Mickael Bourgeois , Clément Bailly , Mathieu Frindel , François Guérard , Michel Chérel , et al.
Expert Opinion on Biological Therapy, 2017, 17 (7), pp.813 - 819. ⟨10.1080/14712598.2017.1322577⟩
Article dans une revue inserm-01635514v1
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PET Imaging for Initial Staging and Therapy Assessment in Multiple Myeloma Patients

Clément Bailly , Rodolphe Leforestier , Bastien Jamet , Thomas Carlier , Mickael Bourgeois , et al.
International Journal of Molecular Sciences, 2017, 18 (2), pii: E445. ⟨10.3390/ijms18020445⟩
Article dans une revue inserm-01500327v1
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Radioimmunotherapy for Treatment of Acute Leukemia

Caroline Bodet-Milin , Françoise Kraeber-Bodéré , Thomas Eugène , François Guérard , Joëlle Gaschet , et al.
Seminars in Nuclear Medicine, 2016, 46, pp.135-146. ⟨10.1053/j.semnuclmed.2015.10.007⟩
Article dans une revue inserm-01280232v1
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Prosthetic groups for radioiodination and astatination of peptides and proteins: a comparative study of five potential bioorthogonal labeling strategies

Laurent Navarro , Marion Berdal , Michel Chérel , Frédéric Pecorari , Jean-François Gestin , et al.
Bioorganic and Medicinal Chemistry, In press, pp.167-174. ⟨10.1016/j.bmc.2018.11.034⟩
Article dans une revue inserm-01939636v1
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Reply to the 'Comment on "Investigation of Zr(IV) and 89 Zr(IV) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging"' by A. Bianchi and M. Savastano, Chem. Commun., 2020, 56, D0CC01189D

François Guérard , Yong-Sok Lee , Raphaël Tripier , Lawrence Szajek , Jeffrey Deschamps , et al.
Chemical Communications, 2020, Online ahead of print. ⟨10.1039/d0cc03594g⟩
Article dans une revue inserm-02947405v1
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New Advances in Radioimmunotherapy for the Treatment of Cancers

Clément Bailly , Caroline M Bodet-Milin , Caroline Rousseau , François Guérard , Thomas Carlier , et al.
Bench to Bedside Immunotherapy of Cancers, ch 29, Springer, pp.563-585, 2020, Cancer Immunology, 978-3-030-50286-7. ⟨10.1007/978-3-030-50287-4_29⟩
Chapitre d'ouvrage inserm-03016103v1
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O-66 - Preparation of 211At-labeled aromatic compounds from thioarylprecursors

Clémence Maingueneau , Romain Eychenne , Jean-François Gestin , François Guérard
International Symposium of radiopharmaceutical sciences, May 2022, Nantes, France
Communication dans un congrès inserm-03842544v1
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Investigation on the reactivity of nucleophilic radiohalogens with arylboronic acids in water: access to an efficient single-step method for the radioiodination and astatination of antibodies

Marion Berdal , Sébastien Gouard , Romain Eychenne , Séverine Marionneau-Lambot , Mikaël Croyal , et al.
Chemical Science, 2021, 12 (4), pp.1458-1468. ⟨10.1039/D0SC05191H⟩
Article dans une revue inserm-03024891v1