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Prion 'most infectious' particles-When size matters

 Florent Laferrière , Philippe Tixador , Laetitia Herzog , Jerome Chapuis , Fabienne Reine , et al.
International Prion Congress Prion 2012, May 2012, Amsterdam, Netherlands
Communication dans un congrès hal-02747443v1
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Highly Infectious Prions Generated by a Single Round of Microplate-Based Protein Misfolding Cyclic Amplification

 Mohammed Moudjou , Pierre Sibille , Guillaume Fichet , Fabienne Reine , Jérôme Chapuis , et al.
mBio, 2014, 5 (1), ⟨10.1128/mBio.00829-13⟩
Article dans une revue hal-03402322v1
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Novel self-replicating α-synuclein polymorphs that escape ThT monitoring can spontaneously emerge and acutely spread in neurons

 Francesca de Giorgi , Florent Laferrière , Federica Zinghirino , Emilie Faggiani , Alons Lends , et al.
Science Advances , 2020, 6 (40), pp.eabc4364. ⟨10.1126/sciadv.abc4364⟩
Article dans une revue hal-02964382v1

Memory Decline and Its Reversal in Aging and Neurodegeneration Involve miR-183/96/182 Biogenesis

 Ali Jawaid , Bisrat Woldemichael , Eloïse Kremer , Florent Laferriere , Niharika Gaur , et al.
Molecular Neurobiology, 2019, 56 (5), pp.3451-3462. ⟨10.1007/s12035-018-1314-3⟩
Article dans une revue hal-03402002v1
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Overexpression of α-Synuclein by Oligodendrocytes in Transgenic Mice Does Not Recapitulate the Fibrillar Aggregation Seen in Multiple System Atrophy

 Florent Laferrière , Xin He , Federica Zinghirino , Evelyne Doudnikoff , Emilie Faggiani , et al.
Cells, 2020, 9 (11), pp.2371. ⟨10.3390/cells9112371⟩
Article dans une revue hal-03012542v1
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Overexpression of α-Synuclein by Oligodendrocytes in Transgenic Mice Does Not Recapitulate the Fibrillar Aggregation Seen in Multiple System Atrophy

 Florent Laferrière , Xin He , Federica Zinghirino , Evelyne Doudnikoff , Emilie Faggiani , et al.
Cells, 2020, 9 (11), pp.2371. ⟨10.3390/cells9112371⟩
Article dans une revue hal-03401948v1
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Quaternary Structure of Pathological Prion Protein as a Determining Factor of Strain-Specific Prion Replication Dynamics

 Florent Laferrière , Philippe Tixador , Mohammed Moudjou , Jérôme Chapuis , Pierre Sibille , et al.
PLoS Pathogens, 2013, 9 (10), ⟨10.1371/journal.ppat.1003702⟩
Article dans une revue hal-03402326v1
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A model of human neural networks reveals NPTX2 pathology in ALS and FTLD

 Marian Hruska-Plochan , Vera I Wiersma , Katharina M Betz , Izaskun Mallona , Silvia Ronchi , et al.
Nature, In press, ⟨10.1038/s41586-024-07042-7⟩
Article dans une revue hal-04466545v1
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Protease resistance of infectious prions is suppressed by removal of a single atom in the cellular prion protein

 Henning Leske , Simone Hornemann , Uli Simon Herrmann , Caihong Zhu , Paolo Dametto , et al.
PLoS ONE, 2017, 12 (2), pp.e0170503. ⟨10.1371/journal.pone.0170503⟩
Article dans une revue hal-03402308v1
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Quaternary structure of pathological prion protein as a determining factor of strain-specific prion replication dynamics

 Florent Laferrière , Philippe Tixador , Mohammed M. Moudjou , Jerome Chapuis , Pierre Sibille , et al.
PLoS Pathogens, 2013, 9 (10), ⟨10.1371/journal.ppat.1003702⟩
Article dans une revue hal-02650542v1
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Biases in α-synuclein immuno-quantitation: a core problem for basic and ancillary studies of Parkinson’s disease and multiple system atrophy

 Florent Laferrière , Ludivine Sabatier , Stéphane Claverol , Francesca de Giorgi , François Ichas
Translational Neurodegeneration, 2024, 13 (1), pp.15. ⟨10.1186/s40035-024-00408-x⟩
Article dans une revue hal-04529171v1
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Identification of distinct pathological signatures induced by patient-derived -synuclein structures in nonhuman primates

 M. Bourdenx , A. Nioche , S. Dovero , M.-L. Arotcarena , S. Camus , et al.
Science Advances , 2020, 6 (20), ⟨10.1126/sciadv.aaz9165⟩
Article dans une revue hal-03403421v1
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Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation

 Tariq Afroz , Eva-Maria Hock , Patrick Ernst , Chiara Foglieni , Melanie Jambeau , et al.
Nature Communications, 2017, 8 (1), ⟨10.1038/s41467-017-00062-0⟩
Article dans une revue hal-03402074v1
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Neurons with Cat’s Eyes: A Synthetic Strain of α-Synuclein Fibrils Seeding Neuronal Intranuclear Inclusions

 Francesca de Giorgi , Muhammed Bilal Abdul-Shukkoor , Marianna Kashyrina , Leslie-Ann Largitte , Francesco de Nuccio , et al.
Biomolecules, 2022, 12 (3), pp.436. ⟨10.3390/biom12030436⟩
Article dans une revue hal-03628777v1
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Similar neuronal imprint and absence of cross-seeded partner fibrils in α-synuclein aggregates from MSA and Parkinson’s disease brains

 Florent Laferrière , Stéphane Claverol , Erwan Bezard , Francesca de Giorgi , François Ichas
2023
Pré-publication, Document de travail hal-04264921v1
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Highly infectious prions generated by a single round of microplate-based protein misfolding cyclic amplification

 Mohammed M. Moudjou , Pierre Sibille , Guillaume Fichet , Fabienne Reine , Jerome Chapuis , et al.
International Prion Congress 2014, May 2014, Trieste, Italy. ⟨10.4161/pri.29370⟩
Communication dans un congrès hal-02739413v1
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TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates

 Florent Laferrière , Zuzanna Maniecka , Manuela Pérez-Berlanga , Marian Hruska-Plochan , Larissa Gilhespy , et al.
Nature Neuroscience, 2019, 22 (1), pp.65-77. ⟨10.1038/s41593-018-0294-y⟩
Article dans une revue hal-03401997v1
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Oligodendrocytes Prune Axons Containing α-Synuclein Aggregates In Vivo: Lewy Neurites as Precursors of Glial Cytoplasmic Inclusions in Multiple System Atrophy?

 Francesco de Nuccio , Marianna Kashyrina , Francesca Serinelli , Florent Laferrière , Dario Domenico Lofrumento , et al.
Biomolecules, 2023, 13 (2), pp.269. ⟨10.3390/biom13020269⟩
Article dans une revue hal-03982249v1
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Advances and challenges in understanding the multifaceted pathogenesis of amyotrophic lateral sclerosis

 Florent Laferriere , Magdalini Polymenidou
Swiss Medical Weekly, 2015, ⟨10.4414/smw.2015.14054⟩
Article dans une revue hal-03402317v1
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SarkoSpin: A Technique for Biochemical Isolation and Characterization of Pathological TDP-43 Aggregates

 Manuela Pérez-Berlanga , Florent Laferriere , Magdalini Polymenidou
Bio-protocol , 2019, 9 (22), ⟨10.21769/BioProtoc.3424⟩
Article dans une revue hal-03401980v1
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Similar neuronal imprint and no cross-seeded fibrils in α-synuclein aggregates from MSA and Parkinson’s disease

 Florent Laferrière , Stéphane Claverol , Erwan Bezard , Francesca de Giorgi , François Ichas
npj Parkinson's Disease, 2022, 8 (1), pp.10. ⟨10.1038/s41531-021-00264-w⟩
Article dans une revue hal-03763104v1
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Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function

 Eva-Maria Hock , Zuzanna Maniecka , Marian Hruska-Plochan , Stefan Reber , Florent Laferrière , et al.
Cell Reports, 2018, 24 (4), pp.987-1000.e7. ⟨10.1016/j.celrep.2018.06.094⟩
Article dans une revue inserm-03376140v1
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Targeting α-Synuclein for PD Therapeutics: A Pursuit on All Fronts

 Margaux Teil , Marie-Laure Arotcarena , Emilie Faggiani , Florent Laferriere , Erwan Bezard , et al.
Biomolecules, 2020, 10 (3), pp.391. ⟨10.3390/biom10030391⟩
Article dans une revue hal-03401974v1
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Emergence of stealth polymorphs that escape α-synuclein amyloid monitoring, take over and acutely spread in neurons

 Francesca de Giorgi , Florent Laferrière , Federica Zinghirino , Emilie Faggiani , Alons Lends , et al.
2023
Pré-publication, Document de travail hal-04264891v1
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Early stage prion assembly involves two subpopulations with different quaternary structures and a secondary templating pathway

 Angélique Igel-Egalon , Florent Laferrière , Mohammed Moudjou , Jan Bohl , Mathieu Mezache , et al.
Communications Biology, 2019, 2 (1), pp.1-13. ⟨10.1038/s42003-019-0608-y⟩
Article dans une revue hal-02317910v1
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Memory Decline and Its Reversal in Aging and Neurodegeneration Involve miR-183/96/182 Biogenesis

 Ali Jawaid , Bisrat T Woldemichael , Eloïse A Kremer , Florent Laferriere , Niharika Gaur , et al.
Molecular Neurobiology, 2019, 56 (5), pp.3451-3462. ⟨10.1007/s12035-018-1314-3⟩
Article dans une revue hal-03403398v1
Image document

Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in non-human primates

 M. Bourdenx , A. Nioche , S. Dovero , M.-L. Arotcarena , S. Camus , et al.
Science Advances , 2020, 6 (20), ⟨10.1101/825216⟩
Article dans une revue hal-04264868v1
Image document

Targeting α-synuclein for PD Therapeutics: A Pursuit on All Fronts

 Margaux Teil , Marie-Laure Arotçarena , Emilie Faggiani , Florent Laferrière , Erwan Bézard , et al.
Biomolecules, 2020, 10 (3), pp.391. ⟨10.3390/biom10030391⟩
Article dans une revue inserm-02505663v1
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Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates

 Mathieu Bourdenx , Aurélien Nioche , Sandra Dovero , Marie-Laure Arotcarena , Sandrine M. J. Camus , et al.
Science Advances , 2020, 6 (20), pp.eaaz9165. ⟨10.1126/sciadv.aaz9165⟩
Article dans une revue hal-02611441v1
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Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function

 Eva-Maria Hock , Zuzanna Maniecka , Marian Hruska-Plochan , Stefan Reber , Florent Laferrière , et al.
Cell Reports, 2018, 24 (4), pp.987-1000.e7. ⟨10.1016/j.celrep.2018.06.094⟩
Article dans une revue hal-03402070v1
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