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Florent Figon

I am a post-doc researcher (Ph.D. in Biology) at the Insect Biology Research Institute (CNRS), Tours, France. I am deeply interested in understanding organismal biology with an integrative approach, i.e. at a multiscale and interdisciplinary level. My research focuses on the chemical, molecular and cellular bases of plastic phenotypic traits, and their physiological and ecological consequences. I currently investigate the cyclic biochemical and cellular processes underlying the metabolism of a widespread class of invertebrate pigments, the ommochromes. Ommochromes are involved in a vast array of biological functions, from compound eye-based vision to reversible color change of crab spiders and cephalopods. I aim at unraveling the biochemical and trafficking pathways allowing crab spiders to match the color of the flower on which they hunt by combining state-of-the-art analytical (ultra-high performance liquid chromatography coupled to tandem mass spectrometry), cell imaging (high-pressure freezing, electron microscopy and nano-scale Synchrotron-based X-ray fluorescence) and computational (quantum photochemistry) techniques.

Journal articles5 documents

  • Florent Figon, Jérôme Casas, Ilaria Ciofini, Carlo Adamo. Electronic coupling in the reduced state lies at the origin of color changes of ommochromes. Dyes and Pigments, Elsevier, 2021, 185, pp.108661. ⟨10.1016/j.dyepig.2020.108661⟩. ⟨hal-02954670⟩
  • Florent Figon, Thibaut Munsch, Cecile Croix, Marie-Claude Viaud-Massuard, Arnaud Lanoue, et al.. Uncyclized xanthommatin is a key ommochrome intermediate in invertebrate coloration. Insect Biochemistry and Molecular Biology, Elsevier, 2020, 124, pp.103403. ⟨10.1016/j.ibmb.2020.103403⟩. ⟨hal-02886293⟩
  • Florent Figon, Jérôme Casas. Ommochromes in invertebrates: biochemistry and cell biology. Biological Reviews, Wiley, 2019, 94 (1), pp.156-183. ⟨10.1111/brv.12441⟩. ⟨hal-02333637⟩
  • Léa Ripoll, Xavier Heiligenstein, Ilse Hurbain, Lia Domingues, Florent Figon, et al.. Myosin VI and branched actin filaments mediate membrane constriction and fission of melanosomal tubule carriers. Journal of Cell Biology, Rockefeller University Press, 2018, 217 (8), pp.2709-2726. ⟨10.1083/jcb.201709055⟩. ⟨hal-02349279⟩
  • Ana Llandres Lopez, Florent Figon, Jean-Philippe Christidès, Nicole Mandon, Jérome Casas. Environmental and hormonal factors controlling reversible colour change in crab spiders. Journal of Experimental Biology, Cambridge University Press, 2013, 216 (20), pp.3886-3895. ⟨10.1242/jeb.086470⟩. ⟨hal-01310186⟩

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