Recherche - Archive ouverte HAL Accéder directement au contenu

Filtrer vos résultats

34 résultats

Naphthalene derivatives useful in the treatment of cancer

Mounira Amor-Guéret , Florence Mahuteau-Betzer , Hamza Mameri , Claire Beauvineau
France, Patent n° : PCT/EP2022/061772; WO2022/233824 A1. 2022
Brevet hal-04245413v1

Targeting Conformational Activation of CDK2 Kinase

Morgan Pellerano , Sergey Tcherniuk , Corine Perals , Thi Nhu Ngoc Van , Elsa Garcin , et al.
Biotechnology Journal, 2017, 12 (8), pp.1600531. ⟨10.1002/biot.201600531⟩
Article dans une revue hal-02009855v1

Conception et synthèse de sondes hybrides Epicocconone-Triarylamine : Analyse des interactions ADN-Protéines

Romain Mougeot , Florence Mahuteau-Betzer , Marie-Paule Teulade-Fichou , Stéphane Leleu , Xavier Franck
Rencontres en chimie organique biologique (RECOB, 17, 2018), Mar 2018, Aussois, France
Communication dans un congrès hal-02370829v1
Image document

Mitochondria-targeted cationic porphyrin-triphenylamine hybrids for enhanced two-photon photodynamic therapy

Fabien Hammerer , Florent Poyer , Laura Fourmois , Su Chen , Guillaume Garcia , et al.
Bioorganic and Medicinal Chemistry Letters, 2018, 26 (1), pp.107-118. ⟨10.1016/j.bmc.2017.11.024⟩
Article dans une revue hal-04248717v1

Design and synthesis of epicocconone's analogues as fluorescent dyes for trapping proteins interacting with G-Quadruplex

Stéphane Leleu , Xavier Franck , Romain Mougeot , Florence Mahuteau-Betzer , Marie-Paule Teulade-Fichou
PSL Chemical biology symposium, Dec 2016, Paris, France
Poster de conférence hal-02370783v1
Image document

Protection against retrovirus pathogenesis by SR protein inhibitors.

Anne Keriel , Florence Mahuteau-Betzer , Chantal Jacquet , Marc Plays , David S. Grierson , et al.
PLoS ONE, 2009, 4 (2), pp.e4533. ⟨10.1371/journal.pone.0004533⟩
Article dans une revue hal-00368669v1

Influence of the oxazole ring connection on the fluorescence of oxazoyl-triphenylamine biphotonic DNA probes

Blaise Dumat , Elodie Faurel-Paul , Pauline Fornarelli , Nicolas Saettel , Germain Metgé , et al.
Organic & Biomolecular Chemistry, 2015, 14 (1), pp.358 - 370. ⟨10.1039/C5OB02225H⟩
Article dans une revue cea-01483796v1
Image document

The pyrrolopyrimidine colchicine-binding site agent PP-13 reduces the metastatic dissemination of invasive cancer cells in vitro and in vivo

Pauline Gilson , Morgane Couvet , Laetitia Vanwonterghem , Maxime Henry , Julien Vollaire , et al.
Biochemical Pharmacology, 2019, 160, pp.1-13. ⟨10.1016/j.bcp.2018.12.004⟩
Article dans une revue hal-02347147v1

Inhibition of nonsense-mediated mRNA decay (NMD) by a new chemical molecule reveals the dynamic of NMD factors in P-bodies.

Sébastien Durand , Nicolas Cougot , Florence Mahuteau-Betzer , Chi-Hung Nguyen , David S. Grierson , et al.
Journal of Cell Biology, 2007, 178 (7), pp.1145-60. ⟨10.1083/jcb.200611086⟩
Article dans une revue hal-00259111v1

Ligandless Microwave-Assisted Pd/Cu-Catalyzed Direct Arylation of Oxazoles

François Besselièvre , Florence Mahuteau-Betzer , David S. Grierson , S. Piguel
Journal of Organic Chemistry, 2008, 73 (8), pp.3278-3280
Article dans une revue hal-00325531v1
Image document

Inhibition of nonsense-mediated mRNA decay (NMD) by a new chemical molecule reveals the dynamic of NMD factors in P-bodies

Sébastien Durand , Nicolas Cougot , Florence Mahuteau-Betzer , Chi-Hung Nguyen , David S. Grierson , et al.
Journal of Cell Biology, 2007, 178 (7), pp.1145-1160. ⟨10.1083/jcb.200611086⟩
Article dans une revue inserm-00175728v1
Image document

Selectivity of Terpyridine Platinum Anticancer Drugs for G-quadruplex DNA

Elodie Morel , Claire Beauvineau , Delphine Naud-Martin , Corinne Landras-Guetta , Daniela Verga , et al.
Molecules, 2019, 24 (3), pp.404. ⟨10.3390/molecules24030404⟩
Article dans une revue hal-02050271v1
Image document

Three-component C-H bond sulfonylation of imidazoheterocycles via visible-light organophotoredox catalysis

Chloé Breton-Patient , Delphine Naud-Martin , Florence Mahuteau-Betzer , Sandrine Piguel
European Journal of Organic Chemistry, 2020, ⟨10.1002/ejoc.202001219⟩
Article dans une revue hal-03064627v1

Stereoselective Direct Copper-Catalyzed Alkenylation of Oxazoles with Bromoalkenes

François Besselièvre , S. Piguel , Florence Mahuteau-Betzer , David S. Grierson
Organic Letters, 2008, 10 (18), pp.4029-4032
Article dans une revue hal-00325534v1
Image document

Identification of pyrrolopyrimidine derivative PP-13 as a novel microtubule-destabilizing agent with promising anticancer properties

Pauline Gilson , Fernando Josa-Prado , Claire Beauvineau , Delphine Naud-Martin , Laetitia Vanwonterghem , et al.
Scientific Reports, 2017, 7 (1), pp.10209. ⟨10.1038/s41598-017-09491-9⟩
Article dans une revue inserm-01599698v1

Oblongifolins A-D, polyprenylated benzoylphloroglucinol derivates from Garcinia oblongifolia.

W. Hamed , S. Brajeul , Florence Mahuteau-Betzer , O. Thoison , S. Mons , et al.
Journal of Natural Products, 2006, 69(5), pp.774-777. ⟨10.1021/np050543s⟩
Article dans une revue istex hal-00078476v1
Image document

Ultrabright two-photon excitable red-emissive fluorogenic probes for fast and wash-free bioorthogonal labelling in live cells

Marie Auvray , Delphine Naud-Martin , Gaëlle Fontaine , Frédéric Bolze , Gilles Clavier , et al.
Chemical Science, 2023, 14 (30), pp.8119-8128. ⟨10.1039/D3SC01754K⟩
Article dans une revue hal-04248522v1
Image document

Chimiothèque Nationale

Florence Mahuteau-Betzer
Médecine/Sciences, 2015, 31 (4), pp.417-422. ⟨10.1051/medsci/20153104016⟩
Article dans une revue hal-04248747v1

Design and synthesis of epicocconone's analogues as fluorescent dyes for trapping proteins interacting with G-Quadruplex

Romain Mougeot , Franck Xavier , Stéphane Leleu , Florence Mahuteau-Betzer , Marie-Paule Teulade-Fichou
Journées de chimie organique (JCO, 2016), Sep 2016, Palaiseau, France
Poster de conférence hal-02370768v1

Fluorescent biosensor for detection of the R248Q aggregation‐prone mutant of p53

Morgan Pellerano , Delphine Naud-Martin , Florence Mahuteau-Betzer , Marie Morille , May Catherine Morris
ChemBioChem, 2018, Special Issue: Biosensing and Bioimaging, 20 (4), pp.605-613. ⟨10.1002/cbic.201800531⟩
Article dans une revue hal-02009856v1

Copper-Alkyne Complexation Responsible for the Nucleolar Localization of Quadruplex Nucleic Acid Drugs Labeled by Click Reactions

Joël Lefebvre , Corinne Guetta , Florent Poyer , Florence Mahuteau-Betzer , Marie-Paule Teulade-Fichou
Angewandte Chemie, 2017, 129 (38), pp.11523-11527. ⟨10.1002/ange.201703783⟩
Article dans une revue hal-03061855v1
Image document

Cytidine deaminase deficiency in tumor cells is associated with sensitivity to a naphthol derivative and a decrease in oncometabolite levels

Hamza Mameri , Géraldine Buhagiar-Labarchède , Gaëlle Fontaine , Céline Corcelle , Caroline Barette , et al.
Cellular and Molecular Life Sciences, 2022, 79 (8), pp.465. ⟨10.1007/s00018-022-04487-9⟩
Article dans une revue hal-03766208v1

C-H Bond Activation: A Versatile Protocol for the Direct Arylation and Alkenylation of Oxazoles

François Besselièvre , S. Lebrequier , Florence Mahuteau-Betzer , S. Piguel
Synthesis: Journal of Synthetic Organic Chemistry, 2009, 20, pp.3511-3518
Article dans une revue hal-00423554v1
Image document

Interplay between Cellular Uptake, Intracellular Localization and the Cell Death Mechanism in Triphenylamine-Mediated Photoinduced Cell Death

Rahima Chennoufi , Ngoc-Duong Trinh , Françoise Simon , Guillaume Bordeau , Delphine Naud-Martin , et al.
Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-63991-9⟩
Article dans une revue hal-02614144v1
Image document

Mitochondria-targeted Triphenylamine Derivatives Activatable by Two-Photon Excitation for Triggering and Imaging Cell Apoptosis

Rahima Chennoufi , Houcine Bougherara , Nathalie Gagey-Eilstein , Blaise Dumat , Etienne Henry , et al.
Scientific Reports, 2016, 6 (1), ⟨10.1038/srep21458⟩
Article dans une revue hal-02350542v1

Small-molecule inhibition of HIV pre-mRNA splicing as a novel antiretroviral therapy to overcome drug resistance

N. Bakkour , Yl. Lin , S. Maire , L. Ayadi , Florence Mahuteau-Betzer , et al.
PLoS Pathogens, 2007, 3 (10), pp.1530-1539. ⟨10.1371/journal.ppat.0030159⟩
Article dans une revue hal-00259118v1
Image document

Small-molecule inhibition of HIV pre-mRNA splicing as a novel antiretroviral therapy to overcome drug resistance

N. Bakkour , Yea-Lih Lin , S. Maire , L. Ayadi , Florence Mahuteau-Betzer , et al.
PLoS Pathogens, 2007, 3 (10), pp.e159. ⟨10.1371/journal.ppat.0030159⟩
Article dans une revue hal-00185296v1

TP-2Rho Is a Sensitive Solvatochromic Red-Shifted Probe for Monitoring the Interactions between CDK4 and Cyclin D

Morgan Pellerano , Delphine Naud-Martin , Marion Peyressatre , Camille Prevel , Marie-Paule Teulade-Fichou , et al.
ChemBioChem, 2016, 17 (8), pp.737-744. ⟨10.1002/cbic.201500641⟩
Article dans une revue istex hal-02009852v1

Design and synthesis of Epicocconone-DNA binder hybrids : Analysing the DNA-Protein interaction

Stéphane Leleu , Xavier Franck , Romain Mougeot , Florence Mahuteau-Betzer , Marie-Paule Teulade-Fichou
French-Japanese Symposium of Medicinal and Fine Chemistry (26, 2017), Sep 2017, Strasbourg, France
Poster de conférence hal-02370800v1
Image document

PhenDV, a turn-off fluorescent quadruplex DNA probe for improving the sensitivity of drug screening assays

Claire Beauvineau , Corinne Guetta , Marie-Paule Teulade-Fichou , Florence Mahuteau-Betzer
Organic & Biomolecular Chemistry, 2017, 15 (34), pp.7117-7121. ⟨10.1039/c7ob01705g⟩
Article dans une revue hal-04248623v1