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IL-4–Induced Gene 1: A Negative Immune Checkpoint Controlling B Cell Differentiation and Activation

Lloyd Bod , Laetitia Douguet , Cédric Auffray , Renée Lengagne , Fériel Bekkat , et al.
Journal of Immunology, 2018, 200 (3), pp.1027-1038. ⟨10.4049/jimmunol.1601609⟩
Article dans une revue hal-02346124v1
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IL4I1: an inhibitor of the CD8(+) antitumor T-cell response in vivo.

Fanette Lasoudris , Céline Cousin , Armelle Prevost-Blondel , Nadine Martin-Garcia , Issam Abd-Alsamad , et al.
European Journal of Immunology, 2011, 41 (6), pp.1629-38. ⟨10.1002/eji.201041119⟩
Article dans une revue inserm-00604898v1
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Recurrent mutations of the STAT6 DNA binding domain in primary mediastinal B-cell lymphoma.

Olga Ritz , Chrystelle Guiter , Flavia Castellano , Karola Dorsch , Julia Melzner , et al.
Blood, 2009, 114 (6), pp.1236-42. ⟨10.1182/blood-2009-03-209759⟩
Article dans une revue inserm-00411059v1
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The novel immunosuppressive enzyme IL4I1 is expressed by neoplastic cells of several B-cell lymphomas and by tumor-associated macrophages.

Amélie Carbonnelle-Puscian , Christiane Copie-Bergman , Maryse Baia , Nadine Martin-Garcia , Yves Allory , et al.
Leukemia, 2009, 23 (5), pp.952-60. ⟨10.1038/leu.2008.380⟩
Article dans une revue inserm-00392067v1
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Absence of the Adaptor Protein PEA-15 Is Associated with Altered Pattern of Th Cytokines Production by Activated CD4+ T Lymphocytes In Vitro, and Defective Red Blood Cell Alloimmune Response In Vivo

Stéphane Kerbrat , Benoit Vingert , Marie-Pierre Junier , Flavia Castellano , François Renault-Mihara , et al.
PLoS ONE, 2015, 10 (8), pp.e0136885. ⟨10.1371/journal.pone.0136885⟩
Article dans une revue hal-01235701v1

Emerging Role of IL-4–Induced Gene 1 as a Prognostic Biomarker Affecting the Local T-Cell Response in Human Cutaneous Melanoma

Jan Philipp Ramspott , Fériel Bekkat , Lloyd Bod , Maryline Favier , Benoît Terris , et al.
Journal of Investigative Dermatology, 2018, 138 (12), pp.2625-2634. ⟨10.1016/j.jid.2018.06.178⟩
Article dans une revue hal-02345054v1
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What role for AHR activation in IL4I1-mediated immunosuppression ?

Flavia Castellano , Armelle Prevost-Blondel , José L Cohen , Valérie Molinier-Frenkel
OncoImmunology, 2021, 10 (1), pp.1924500. ⟨10.1080/2162402X.2021.1924500⟩
Article dans une revue hal-03244910v1
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Dichotomy between factors inducing the immunosuppressive enzyme IL-4-induced gene 1 (IL4I1) in B lymphocytes and mononuclear phagocytes.

Jeanine Marquet , Fanette Lasoudris , Céline Cousin , Marie-Line Puiffe , Nadine Martin-Garcia , et al.
European Journal of Immunology, 2010, 40 (9), pp.2557-68. ⟨10.1002/eji.201040428⟩
Article dans une revue inserm-00535509v1
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Control of T-cell activation and signaling by amino-acid catabolizing enzymes

Flavia Castellano , Valérie Molinier-Frenkel
Frontiers in Cell and Developmental Biology, 2020, 8, pp.613416. ⟨10.3389/fcell.2020.613416⟩
Article dans une revue hal-03192105v1

IL-4–Induced Gene 1: A Negative Immune Checkpoint Controlling B Cell Differentiation and Activation

Lloyd Bod , Laetitia Douguet , Cédric Auffray , Renée Lengagne , Fériel Bekkat , et al.
Journal of Immunology, 2018, 200 (3), pp.1027-1038. ⟨10.4049/jimmunol.1601609⟩
Article dans une revue hal-03993671v1
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Antibacterial Properties of the Mammalian L-Amino Acid Oxidase IL4I1.

Marie-Line Puiffe , Isabelle Lachaise , Valérie Molinier-Frenkel , Flavia Castellano
PLoS ONE, 2013, 8 (1), pp.e54589. ⟨10.1371/journal.pone.0054589⟩
Article dans une revue inserm-00796014v1

Antiproliferative Activity of trans-Avicennol from Zanthoxylum chiloperone var. angustifolium against Human Cancer Stem Cells

Gerardo Cebrian-Torrejon , Suzana Assad Kahn , Nathalie Lagarde , Flavia Castellano , Karine Leblanc , et al.
Journal of Natural Products, 2012, 75 (2), pp.257-261. ⟨10.1021/np2004165⟩
Article dans une revue hal-01541436v1