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Past, present and future of vasopressin and oxytocin receptor oligomers, prototypical GPCR models to study dimerization processes
M. Cottet
,
L Albizu
,
S Perkovska
,
Frédéric Jean-Alphonse
,
R Rahmeh
,
et al.
Article dans une revue
hal-03117146v1
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Arachidonic acid-dependent gene regulation during preadipocyte differentiation controls adipocyte potential
Evanthia Nikolopoulou
,
Georgia Papacleovoulou
,
Frédéric Jean-Alphonse
,
Giulia Grimaldi
,
Malcolm Parker
,
et al.
Article dans une revue
hal-03117154v1
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Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release
Yalikun Suofu
,
Wei Li
,
Frédéric Jean-Alphonse
,
Jiaoying Jia
,
Nicolas Khattar
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (38), pp.E7997-E8006. ⟨10.1073/pnas.1705768114⟩
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hal-03117160v1
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Endosomal GPCR signaling turned off by negative feedback actions of PKA and v-ATPase
Alexandre Gidon
,
Mohammad Al-Bataineh
,
Frédéric Jean-Alphonse
,
Hilary Stevenson
,
Tomoyuki Watanabe
,
et al.
Article dans une revue
hal-03117152v1
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β-arrestins and endocrine-related GPCRs
Francesco de Pascali
,
Pauline Raynaud
,
Frédéric Jean-Alphonse
,
Shifa Tahir
,
Véronique Bozon
,
et al.
Chapitre d'ouvrage
hal-03462802v1
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Biased agonist pharmacochaperones of the AVP V2 receptor may treat congenital nephrogenic diabetes insipidus.
Frédéric Jean-Alphonse
,
Sanja Perkovska
,
Marie-Céline Frantz
,
Thierry Durroux
,
Catherine Méjean
,
et al.
Article dans une revue
inserm-00421838v1
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Integration of GPCR signaling and sorting from very early endosomes via opposing APPL1 mechanisms
Silvia Sposini
,
Frederic G. Jean-Alphonse
,
Mohammed Akli Ayoub
,
Affiong Oqua
,
Camilla West
,
et al.
Article dans une revue
hal-02625571v1
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Ca 2+ allostery in PTH-receptor signaling
Alex White
,
Fei Fang
,
Frédéric Jean-Alphonse
,
Lisa Clark
,
Hyun-Jung An
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (8), pp.3294-3299. ⟨10.1073/pnas.1814670116⟩
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hal-03117164v1
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Cdc42 activation couples fluid shear stress to apical endocytosis in proximal tubule cells
Sohinee Bhattacharyya
,
Frédéric Jean-Alphonse
,
Venkatesan Raghavan
,
Jennifer Mcgarvey
,
Youssef Rbaibi
,
et al.
Article dans une revue
hal-03117161v1
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Parathyroid hormone initiates dynamic NHERF1 phosphorylation cycling and conformational changes that regulate NPT2A-dependent phosphate transport
Qiangmin Zhang
,
Kunhong Xiao
,
Jose Paredes
,
Tatyana Mamonova
,
W. Bruce Sneddon
,
et al.
Article dans une revue
hal-03117163v1
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Editorial: Pharmacology of endocrine related GPCRs
Francesco de Pascali
,
Aylin Hanyaloglu
,
Frédéric Jean-Alphonse
,
Francesco Potì
,
Eric Reiter
Article dans une revue
hal-04525032v1
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Regulation of GPCR signal networks via membrane trafficking
Frédéric Jean-Alphonse
,
A.C. Hanyaloglu
Article dans une revue
hal-03117149v1
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G q/11 -dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR
Alex White
,
Frédéric Jean-Alphonse
,
Fei Fang
,
Karina Pena
,
Shi Liu
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (13), pp.7455-7460. ⟨10.1073/pnas.1918158117⟩
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hal-03117167v1
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Actin-Sorting Nexin 27 (SNX27)-Retromer Complex Mediates Rapid Parathyroid Hormone Receptor Recycling
Jennifer Mcgarvey
,
Kunhong Xiao
,
Shanna Bowman
,
Tatyana Mamonova
,
Qiangmin Zhang
,
et al.
Article dans une revue
hal-03117156v1
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Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation
Lisa Clark
,
James Krieger
,
Alex White
,
Vasyl Bondarenko
,
Saifei Lei
,
et al.
Article dans une revue
hal-03117168v1
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Structure and dynamics of the active human parathyroid hormone receptor-1
Li-Hua Zhao
,
Shanshan Ma
,
Ieva Sutkeviciute
,
Dan-Dan Shen
,
X. Edward Zhou
,
et al.
Article dans une revue
hal-03117165v1
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Use of backbone modification to enlarge the spatiotemporal diversity of parathyroid hormone receptor-1 signaling via biased agonism
Shi Liu
,
Frédéric Jean-Alphonse
,
Alex D. White
,
Denise Wootten
,
Patrick M. Sexton
,
et al.
Article dans une revue
hal-03117166v1
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Spatially Restricted G Protein-coupled Receptor Activity via Divergent Endocytic Compartments
Frédéric Jean-Alphonse
,
Shanna Bowersox
,
Stanford Chen
,
Gemma Beard
,
Manojkumar Puthenveedu
,
et al.
Article dans une revue
hal-03117150v1
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The polycystin-1, lipoxygenase, and α -toxin domain regulates polycystin-1 trafficking
Yaoxian Xu
,
Andrew Streets
,
Andrea Hounslow
,
Uyen Tran
,
Frédéric Jean-Alphonse
,
et al.
Article dans une revue
hal-03117155v1
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Design and synthesis of cyclic and linear peptide-agarose tools for baiting interacting protein partners of GPCRs
Sébastien Granier
,
Frédéric Jean-Alphonse
,
Hélène Déméné
,
Gilles Guillon
,
Robert Pascal
,
et al.
Article dans une revue
istex
hal-03117141v1
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Biased signaling and allosteric modulation at the FSHR
Flavie Landomiel
,
Francesco de Pascali
,
Pauline Raynaud
,
Frédéric Jean-Alphonse
,
Romain Yvinec
,
et al.
Article dans une revue
hal-02362523v1
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PTH hypersecretion triggered by a GABAB1 and Ca2+-sensing receptor heterocomplex in hyperparathyroidism
Wenhan Chang
,
Chia-Ling Tu
,
Frédéric Jean-Alphonse
,
Amanda Herberger
,
Zhiqiang Cheng
,
et al.
Article dans une revue
hal-03117169v1
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Design and validation of the first cell-impermeant melatonin receptor agonist
Florence Gbahou
,
Erika Cecon
,
Guillaume Viault
,
Romain Gerbier
,
Frédéric Jean-Alphonse
,
et al.
Article dans une revue
hal-02873466v1
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Endosomal generation of cAMP in GPCR signaling
Jean-Pierre Vilardaga
,
Frédéric Jean-Alphonse
,
Thomas Gardella
Article dans une revue
hal-03117153v1
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Intracellular VHHs to monitor and modulate GPCR signaling
Pauline Raynaud
,
Camille Gauthier
,
Vinesh Jugnarain
,
Frédéric Jean-Alphonse
,
Eric Reiter
,
et al.
Article dans une revue
hal-03892398v1
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Combined multiplexed phage display, high-throughput sequencing, and functional assays as a platform for identifying modulatory VHHs targeting the FSHR
Anielka Zehnaker
,
Amandine Vallet
,
Juliette Gourdon
,
Caterina Sarti
,
Vinesh Jugnarain
,
et al.
Article dans une revue
hal-04274818v1
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Pharmacological characterization of low molecular weight biased agonists at the follicle stimulating hormone receptor
Francesco de Pascali
,
Mohammed Akli Ayoub
,
Riccardo Benevelli
,
Silvia Sposini
,
Jordan Lehoux
,
et al.
Article dans une revue
hal-03351267v1
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Confocal and TIRF microscopy based approaches to visualize arrestin trafficking in living cells
Frédéric Jean-Alphonse
,
Silvia Sposini
Chapitre d'ouvrage
hal-03476372v1
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A single domain intrabody targeting the follicle-stimulating hormone receptor (FSHR) impacts FSH-induced G protein-dependent signalling
Pauline Raynaud
,
Vinesh Jugnarain
,
Océane Vaugrente
,
Amandine Vallet
,
Thomas Boulo
,
et al.
Article dans une revue
hal-04269864v1
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Highly-Sensitive In Vitro Bioassays for FSH, TSH, PTH, Kp, and OT in Addition to LH in Mouse Leydig Tumor Cell
Danièle Klett
,
Lucie Pellissier
,
Didier Lomet
,
Flavie Derouin-Tochon
,
Vincent Robert
,
et al.
Article dans une revue
hal-04206799v1
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