Fédérico Perche

Documents

Publications

	In Cellulo and In Vivo Comparison of Cholesterol, Beta-Sitosterol and Dioleylphosphatidylethanolamine for Lipid Nanoparticle Formulation of mRNA Ayoub Medjmedj , Albert Ngalle-Loth , Rudy Clemençon , Josef Hamacek , Chantal Pichon Nanomaterials, 2022, 12 (14), pp.2446. ⟨10.3390/nano12142446⟩ Article dans une revue hal-03727652v1
	DNA minicircles as novel STAT3 decoy oligodeoxynucleotides endowed with anticancer activity in triple-negative breast cancer Geoffrey Casas , Federico Perche , Patrick Midoux , Chantal Pichon , Jean-Marc Malinge Molecular Therapy - Nucleic Acids, 2022, 29, pp.162-175. ⟨10.1016/j.omtn.2022.06.012⟩ Article dans une revue hal-03727647v1
	Nanomedicine-Based Approaches for mRNA Delivery Satoshi Uchida , Federico Perche , Chantal Pichon , Horacio Cabral Molecular Pharmaceutics, 2020, 17 (10), pp.3654 - 3684. ⟨10.1021/acs.molpharmaceut.0c00618⟩ Article dans une revue hal-02995814v1
	Co-delivery of NS1 and BMP2 mRNAs to murine pluripotent stem cells leads to enhanced BMP-2 expression and osteogenic differentiation Pinpin Wang , Delphine Logeart-Avramoglou , Hervé Petite , Cristine Gonçalves , Patrick Midoux Acta Biomaterialia, 2020, 108, pp.337-346. ⟨10.1016/j.actbio.2020.03.045⟩ Article dans une revue hal-02553030v1
	Deciphering the Biological Activities of Dunaliella sp. Aqueous Extract from Stressed Conditions on Breast Cancer: from in Vitro to in Vivo Investigations Fatma Elleuch , Patrick Baril , Mohamed Barkallah , Federico Perche , Slim Abdelkafi International Journal of Molecular Sciences, 2020, 21 (5), pp.1719. ⟨10.3390/ijms21051719⟩ Article dans une revue hal-02553031v1
	Glucose-linked sub-50-nm unimer polyion complex-assembled gold nanoparticles for targeted siRNA delivery to glucose transporter 1-overexpressing breast cancer stem-like cells Yu Yi , Hyun Jin Kim , Meng Zheng , Peng Mi , Mitsuru Naito Journal of Controlled Release, 2019, 295, pp.268 - 277. ⟨10.1016/j.jconrel.2019.01.006⟩ Article dans une revue hal-02995629v1
	RNA-based therapy for osteogenesis Pinpin Wang , Federico Perche , Delphine Logeart-Avramoglou , Chantal Pichon International Journal of Pharmaceutics, 2019, 569, pp.118594. ⟨10.1016/j.ijpharm.2019.118594⟩ Article dans une revue hal-02995602v1
	Neutral Lipopolyplexes for In Vivo Delivery of Conventional and Replicative RNA Vaccine Federico Perche , Rudy Clemençon , Kai Schulze , Thomas Ebensen , Carlos Guzman Molecular Therapy - Nucleic Acids, 2019, 17, pp.767-775. ⟨10.1016/j.omtn.2019.07.014⟩ Article dans une revue hal-02321815v1
	Cardiolipin-Based Lipopolyplex Platform for the Delivery of Diverse Nucleic Acids into Gram-Negative Bacteria Federico Perche , Tony Le Gall , Tristan Montier , Chantal Pichon , Jean-Marc Malinge Pharmaceuticals, 2019, 12 (2), pp.81. ⟨10.3390/ph12020081⟩ Article dans une revue hal-02172973v1
	Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety Kevin van Der Jeught , Stefaan de Koker , Lukasz Bialkowski , Carlo Heirman , Patrick Tjok Joe ACS Nano, 2018, 12 (10), pp.9815-9829. ⟨10.1021/acsnano.8b00966⟩ Article dans une revue hal-01889829v1
	Improved brain expression of anti-amyloid β scFv by complexation of mRNA including a secretion sequence with PEG-based block catiomer Federico Perche , Satoshi Uchida , Hiroki Akiba , Chin-Yu Lin , Masaru Ikegami Current Alzheimer Research, 2017, 14 (3), pp.295-302. ⟨10.2174/1567205013666161108110031⟩ Article dans une revue hal-02130712v1
	Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles Chin-Yu Lin , Federico Perche , Masaru Ikegami , Satoshi Uchida , Kazunori Kataoka Journal of Controlled Release, 2016, 235, pp.268-275. ⟨10.1016/j.jconrel.2016.06.001⟩ Article dans une revue hal-02995717v1
	Hypoxia-Responsive Copolymer for siRNA Delivery Federico Perche , Swati Biswas , Niravkumar Patel , Vladimir Torchilin Methods in Molecular Biology, 2016, 1372 : RNA Imaging, pp.139-162. ⟨10.1007/978-1-4939-3148-4_12⟩ Article dans une revue hal-02130872v1
	Hydroxychloroquine-conjugated gold nanoparticles for improved siRNA activity Federico Perche , Y. Yi , L. Hespel , P Mi , A Dirisala Biomaterials, 2016, 90, pp.62-71. ⟨10.1016/j.biomaterials.2016.02.027⟩ Article dans une revue hal-02130728v1
	Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles Chin-Yu Lin , Federico Perche , Masaru Ikegami , Satoshi Uchida , Kazunori Kataoka Journal of Controlled Release, 2016, 235, pp.268-275. ⟨10.1016/j.jconrel.2016.06.001⟩ Article dans une revue hal-02130718v1
	Improved brain expression of anti-amyloid β scFv by complexation of mRNA including a secretion sequence with PEG-based block catiomer Federico Perche , Satoshi Uchida , Hiroki Akiba , Chin-Yu Lin , Masaru Ikegami Current Alzheimer Research, 2015, 1 (999), pp.1-1. ⟨10.2174/1567205013666161108110031⟩ Article dans une revue hal-02995714v1
	Polymeric micelles containing reversibly phospholipid-modified anti-survivin siRNA: A promising strategy to overcome drug resistance in cancer G. Salzano , R. Riehle , G. de Rosa , V.P. P Torchilin , Riehle Rdrhielde Cancer Letters, 2014, 343 (2), pp.224 - 231. ⟨10.1016/j.canlet.2013.09.037⟩ Article dans une revue hal-02995789v1
	Novel Nanostructured Lipid Carrier Co-Loaded with Doxorubicin and Docosahexaenoic Acid Demonstrates Enhanced in Vitro Activity and Overcomes Drug Resistance in MCF-7/Adr Cells Samuel V Mussi , Rupa Sawant , Federico Perche , Mônica C Oliveira , Ricardo B Azevedo Pharmaceutical Research, 2014, 31 (8), pp.1882 - 1892. ⟨10.1007/s11095-013-1290-2⟩ Article dans une revue hal-02995777v1
	Hypoxia-Targeted siRNA Delivery Federico Perche , S. Biswas , T. Wang , L. Zhu , V. Torchilin Angewandte Chemie International Edition, 2014, 53 (13), pp.3362-3366. ⟨10.1002/anie.201308368⟩ Article dans une revue hal-02130753v1
	Matrix metalloproteinase 2-sensitive multifunctional polymeric micelles for tumor-specific co-delivery of siRNA and hydrophobic drugs Tao Wang , Lin Zhu , Federico Perche , Anton Taigind , Vladimir P Torchilin Biomaterials, 2014, 35 (13), pp.4213 - 4222. ⟨10.1016/j.biomaterials.2014.01.060⟩ Article dans une revue hal-02995779v1
	Matrix metalloproteinase 2-sensitive multifunctional polymeric micelles for tumor-specific co-delivery of siRNA and hydrophobic drugs Lin Zhu , Federico Perche , Tao Wang , Vladimir Torchilin Biomaterials, 2014, 35 (13), pp.4213-4222. ⟨10.1016/j.biomaterials.2014.01.060⟩ Article dans une revue hal-02130742v1
	Novel Nanostructured Lipid Carrier Co-Loaded with Doxorubicin and Docosahexaenoic Acid Demonstrates Enhanced in Vitro Activity and Overcomes Drug Resistance in MCF-7/Adr Cells Samuel Mussi , Rupa Sawant , Federico Perche , Mônica Oliveira , Ricardo Azevedo Pharmaceutical Research, 2014, 31 (8), pp.1882-1892. ⟨10.1007/s11095-013-1290-2⟩ Article dans une revue hal-02130734v1
	Polymeric micelles containing reversibly phospholipid-modified anti-survivin siRNA: A promising strategy to overcome drug resistance in cancer G. Salzano , R. Riehle , G. Navarro , Federico Perche , G. de Rosa Cancer Letters, 2014, 343 (2), pp.224-231. ⟨10.1016/j.canlet.2013.09.037⟩ Article dans une revue hal-02130786v1
	Recent Trends in Multifunctional Liposomal Nanocarriers for Enhanced Tumor Targeting Federico Perche , Vladimir P Torchilin Journal of Drug Delivery, 2013, 2013, pp.1 - 32. ⟨10.1155/2013/705265⟩ Article dans une revue hal-02995820v1
	Enhanced anticancer activity of nanopreparation containing an MMP2-sensitive PEG-drug conjugate and cell-penetrating moiety Lin Zhu , Tao Wang , Federico Perche , Anton Taigind , Vladimir Torchilin Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (42), pp.17047-17052. ⟨10.1073/pnas.1304987110⟩ Article dans une revue hal-02130803v1
	Recent Trends in Multifunctional Liposomal Nanocarriers for Enhanced Tumor Targeting Federico Perche , Vladimir Torchilin Journal of Drug Delivery, 2013, 2013, pp.1-32. ⟨10.1155/2013/705265⟩ Article dans une revue hal-02130868v1
	Octa-arginine-modified pegylated liposomal doxorubicin: An effective treatment strategy for non-small cell lung cancer Swati Biswas , Pranali Deshpande , Federico Perche , Namita Dodwadkar , Shailendra Sane Cancer Letters, 2013, 335 (1), pp.191-200. ⟨10.1016/j.canlet.2013.02.020⟩ Article dans une revue hal-02130808v1
	Enhanced anticancer activity of nanopreparation containing an MMP2-sensitive PEG-drug conjugate and cell-penetrating moiety Lin Zhu , Federico Perche , Tao Wang , Anton Taigind , Vladimir P Torchilin Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (42), pp.17047 - 17052. ⟨10.1073/pnas.1304987110⟩ Article dans une revue hal-02995791v1
	Octa-arginine-modified pegylated liposomal doxorubicin: An effective treatment strategy for non-small cell lung cancer Swati Biswas , Pranali P Deshpande , Federico Perche , Namita S Dodwadkar , Shailendra D Sane Cancer Letters, 2013, 335 (1), pp.191 - 200. ⟨10.1016/j.canlet.2013.02.020⟩ Article dans une revue hal-02995795v1
	Accumulation and toxicity of antibody-targeted doxorubicin-loaded PEG–PE micelles in ovarian cancer cell spheroid model Federico Perche , Niravkumar Patel , Vladimir Torchilin Journal of Controlled Release, 2012, 164 (1), pp.95-102. ⟨10.1016/j.jconrel.2012.09.003⟩ Article dans une revue hal-02130810v1
	Gene transfer by histidylated lipopolyplexes: A dehydration method allowing preservation of their physicochemical parameters and transfection efficiency Federico Perche , Olivier Lambert , Mathieu Berchel , Paul-Alain Jaffres , Chantal Pichon International Journal of Pharmaceutics, 2012, 423 (1), pp.144 - 150. ⟨10.1016/j.ijpharm.2011.04.009⟩ Article dans une revue hal-02995807v1
	Accumulation and toxicity of antibody-targeted doxorubicin-loaded PEG–PE micelles in ovarian cancer cell spheroid model Federico Perche , Nirav Patel , Vladimir P Torchilin Journal of Controlled Release, 2012, 164 (1), pp.95 - 102. ⟨10.1016/j.jconrel.2012.09.003⟩ Article dans une revue hal-02995799v1
	Cancer cell spheroids as a model to evaluate chemotherapy protocols Federico Perche , Vladimir P Torchilin Cancer Biology and Therapy, 2012, 13 (12), pp.1205 - 1213. ⟨10.4161/cbt.21353⟩ Article dans une revue hal-02995802v1
	Selective gene delivery in dendritic cells with mannosylated and histidylated lipopolyplexes. Federico Perche , David Gosset , Mathieu Mével , Marie-Laure Miramon , Jean-Jacques Yaouanc Journal of Drug Targeting, 2011, 19 (5), pp.315-25. ⟨10.3109/1061186X.2010.504262⟩ Article dans une revue hal-00753554v1
	Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA. Federico Perche , Thierry Benvegnu , Mathieu Berchel , Loic Lebegue , Chantal Pichon Nanomedicine: Nanotechnology, Biology and Medicine, 2011, 7 (4), pp.445-53. ⟨10.1016/j.nano.2010.12.010⟩ Article dans une revue hal-00754373v1

	High Efficiency of Histidylated-based Lipid Formulations for mRNA Transfection of Human Schwann Cells N Laroui , C Delehedde , C Goncalves , F Godin , Federico Perche SFNano 2021, Dec 2021, Angers, France Communication dans un congrès hal-03668422v1

	Improved osteogenic commitment of BMP2 mRNA-transfected MSCs using NS1 mRNA Pinpin Wang , Delphine Logeart , Lucie Pigeon , Cristine Gonçalves , Hervé Petite ASGCT 2019, Apr 2020, Washington, United States Poster de conférence hal-03668438v1
	Neutral lipopolyplexes for in Vivo delivery of Conventional and replicative RNA vaccine Federico Perche , R Clemençon , K Schulze , T Ebesen , Chantal Pichon mRNA Health Conference 2020, Nov 2020, Boston (virtual), United States Poster de conférence hal-03668439v1

	Stimuli-Sensitive Polymeric Nanomedicines for Cancer Imaging and Therapy Federico Perche , S. Biswas , V. Torchilin Handbook of polymers for pharmaceutical technologies, John Wiley & Sons, Inc., pp.311-344, 2015 Chapitre d'ouvrage hal-02130886v1

	HYPOXIA-TARGETED DELIVERY SYSTEM FOR PHARMACEUTICAL AGENTS Vladimir Torchilin , Swati Biswas , Federico Perche France, Patent n° : WO2015061321. 2015 Brevet hal-02130900v1
	COPOLYMERS FOR THE DELIVERY OF DRUGS INTO CELLS L. Zhu , Federico Perche , Vladimir Torchilin France, Patent n° : WO2014085579. 2014 Brevet hal-02130892v1

Fédérico Perche

Publications

In Cellulo and In Vivo Comparison of Cholesterol, Beta-Sitosterol and Dioleylphosphatidylethanolamine for Lipid Nanoparticle Formulation of mRNA

DNA minicircles as novel STAT3 decoy oligodeoxynucleotides endowed with anticancer activity in triple-negative breast cancer

Nanomedicine-Based Approaches for mRNA Delivery

Co-delivery of NS1 and BMP2 mRNAs to murine pluripotent stem cells leads to enhanced BMP-2 expression and osteogenic differentiation

Deciphering the Biological Activities of Dunaliella sp. Aqueous Extract from Stressed Conditions on Breast Cancer: from in Vitro to in Vivo Investigations

Glucose-linked sub-50-nm unimer polyion complex-assembled gold nanoparticles for targeted siRNA delivery to glucose transporter 1-overexpressing breast cancer stem-like cells

RNA-based therapy for osteogenesis

Neutral Lipopolyplexes for In Vivo Delivery of Conventional and Replicative RNA Vaccine

Cardiolipin-Based Lipopolyplex Platform for the Delivery of Diverse Nucleic Acids into Gram-Negative Bacteria

Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety

Improved brain expression of anti-amyloid β scFv by complexation of mRNA including a secretion sequence with PEG-based block catiomer

Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles

Hypoxia-Responsive Copolymer for siRNA Delivery

Hydroxychloroquine-conjugated gold nanoparticles for improved siRNA activity

Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles

Improved brain expression of anti-amyloid β scFv by complexation of mRNA including a secretion sequence with PEG-based block catiomer

Polymeric micelles containing reversibly phospholipid-modified anti-survivin siRNA: A promising strategy to overcome drug resistance in cancer

Novel Nanostructured Lipid Carrier Co-Loaded with Doxorubicin and Docosahexaenoic Acid Demonstrates Enhanced in Vitro Activity and Overcomes Drug Resistance in MCF-7/Adr Cells

Hypoxia-Targeted siRNA Delivery

Matrix metalloproteinase 2-sensitive multifunctional polymeric micelles for tumor-specific co-delivery of siRNA and hydrophobic drugs

Matrix metalloproteinase 2-sensitive multifunctional polymeric micelles for tumor-specific co-delivery of siRNA and hydrophobic drugs

Novel Nanostructured Lipid Carrier Co-Loaded with Doxorubicin and Docosahexaenoic Acid Demonstrates Enhanced in Vitro Activity and Overcomes Drug Resistance in MCF-7/Adr Cells

Polymeric micelles containing reversibly phospholipid-modified anti-survivin siRNA: A promising strategy to overcome drug resistance in cancer

Recent Trends in Multifunctional Liposomal Nanocarriers for Enhanced Tumor Targeting

Enhanced anticancer activity of nanopreparation containing an MMP2-sensitive PEG-drug conjugate and cell-penetrating moiety

Recent Trends in Multifunctional Liposomal Nanocarriers for Enhanced Tumor Targeting

Octa-arginine-modified pegylated liposomal doxorubicin: An effective treatment strategy for non-small cell lung cancer

Enhanced anticancer activity of nanopreparation containing an MMP2-sensitive PEG-drug conjugate and cell-penetrating moiety

Octa-arginine-modified pegylated liposomal doxorubicin: An effective treatment strategy for non-small cell lung cancer

Accumulation and toxicity of antibody-targeted doxorubicin-loaded PEG–PE micelles in ovarian cancer cell spheroid model

Gene transfer by histidylated lipopolyplexes: A dehydration method allowing preservation of their physicochemical parameters and transfection efficiency

Accumulation and toxicity of antibody-targeted doxorubicin-loaded PEG–PE micelles in ovarian cancer cell spheroid model

Cancer cell spheroids as a model to evaluate chemotherapy protocols

Selective gene delivery in dendritic cells with mannosylated and histidylated lipopolyplexes.

Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA.

High Efficiency of Histidylated-based Lipid Formulations for mRNA Transfection of Human Schwann Cells

Improved osteogenic commitment of BMP2 mRNA-transfected MSCs using NS1 mRNA

Neutral lipopolyplexes for in Vivo delivery of Conventional and replicative RNA vaccine

Stimuli-Sensitive Polymeric Nanomedicines for Cancer Imaging and Therapy

HYPOXIA-TARGETED DELIVERY SYSTEM FOR PHARMACEUTICAL AGENTS

COPOLYMERS FOR THE DELIVERY OF DRUGS INTO CELLS