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Federica Calevro

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**Federica Calevro-Eisenlohr** ORCID: 0000-0001-7856-9617 IdHAL: federica-calevro ### **Positions** Since Sept. 2020 INRAE Research Director (DR2), BF2i Unit (INRAE – INSA Lyon) Lyon, France 2004-2020 Associate Professor, Department of Biosciences (INSA Lyon) and BF2i Unit, Lyon, France 2001-2004 Temporary Lecturer and Research Assistant, Department of Biosciences (INSA Lyon) and BF2i Unit, Lyon, France **Other appointments or responsabilities** Since Jan. 2021 INSA Lyon Directors’ Board Since Jan. 2021 Head of the BF2i Unit, Lyon, France Since Jan. 2021 Member (elected) of the scientific advisory board of the INRAE Plant Health and Environment (SPE) Division 2018-present Member of the pedagogic and orientation advisory board of the E2M2 (Evolution, Ecosystems, Microbiology &amp; Modeling) Doctoral School, University of Lyon 2017-present Co-coordinator of the French Aphid research network (BAPOA, more than 230 members in France, Belgium and Switzerland) of the INRAE SPE Division 2015-present Leader of the Trophic Symbioses team (SymT), BF2i Unit, Lyon 2015-2020 Deputy Head of the BF2i Unit, Lyon 2012-2020 Director of the Biology teaching service and member of the Executive Committe of the Department of Biosciences, INSA Lyon ### **Education and Training** 2018 Accreditation to supervise research (French HDR), INSA Lyon and University of Lyon 2000-2001 Postdoctoral Fellow, Pasteur Institute of Lille, Lille, France 1999-2000 Postdoctoral Fellow WHO, International Agency of Research on Cancer (IARC), Lyon, France 1995-1998 PhD, Biology (Cell and Developmental Biology) and Research Assistant, Department of Physiology and Biochemistry, University of Pisa, Italy 1998 Visiting Scientist, Brain Research Institute, University of Bremen, Germany 1997 Visiting Scientist, Department of Biochemistry, University of Bremen, Germany 1996 Professional Qualification (Biologist), University of Pisa, Italy, summa cum laude (50/50 cum laude) 1995 Diploma of Laurea, Molecular and Developmental Biology, University of Pisa, Italy, summa cum laude (110/110 cum laude) ### **Awards** 2000-2001 Director’s Fellow from the Pasteur Institute of Lille (Post-doc position) 1999-2000 WHO Fellowship (Post-doc position at IARC) 1998 Brain Research Institute Fellowship (visit to Bremen University, G. Roth lab) 1997 EMBO Short term Fellowship (visit to Bremen University, D. Beyersmann lab) 1997 Doctoral Mobility Fellowship from the University of Pisa (visit to Bremen University) 1995-1998 Doctoral Fellowship from the Italian National Agency for new technologies, Energy and sustainable Economic development (ENEA) 1994-1995 Pre-Graduate Fellowship from University of Pisa (1-year laboratory training) ### **Supervision of graduate students and post-doc fellows** ### Since 1995: ### 7 Postdocs ### 7 PhD students (degrees obtained in 2004, 2008, 2010, 2011, 2016, 2020, 2021) 6 have been recruited as Scientists (5 permanent positions/1 post-doc). 2 PhD projects are ongoing. ### 20 Master Students (11 M2 level and 9 M1 level). ### 3 students from University Institutes (*e.g.* IUT). ### **Teaching** ### Since 2020: INSA-Lyon, 12 h/year: Molecular genetics. ### 2001-2020: INSA-Lyon. 200-220 h/year: Anatomy, Biotechnology, Cell biology, Molecular genetics. ### 1995-1998: University of Pisa. 50 h/year: Molecular biology, Molecular toxicology, Comparative anatomy. **Fundings** 43 funded research projects: 2 International, 4 European, 2 IDEX and 6 ANR Programs, 1 France-Génomique grant, 1 Agropolis Foundation grant, 1 SPE-INRAE grant, 4 regional grants, 4 INSA Bonus, 4 INSA Invited Professorships, 4 FR BioEEnViS grants, 4 Investment Programs, 6 projects with industry (including 1 ANR). ### **Scientific Impact and other scientific output** ***Publications:*** 50 original publications, 2 invited reviews, 6 invited contributions to book chapters, 2323 citations, H-index 24, i10-index 33. ***Metabolic databases for arthropod genomes (most recent):*** 1) **DakvicCyc**, <http://arthropodacyc.cycadsys.org/DAKVI/>, *Daktulosphaira vitifoliae*, doi: 10.1186/s12915-020-00820-5 ; 2) **OruabCyc** et **AthroCyc**, <http://arthropodacyc.cycadsys.org/ORUAB/> et <http://arthropodacyc.cycadsys.org/ATHRO/>, *Orussus abietinus* et *Athalia rosae*, doi: 10.1093/gbe/**,** 3) **SitorCyc**, <http://arthropodacyc.cycadsys.org/SITOR/>, *Sitophilus oryzae*, doi: 10.1186/s12915-021-01158-2; **ArtSymbioCyc** (<http://artsymbiocyc.cycadsys.org/>) project containing the reconstruction of the integrated symbiotic metabolism between arthropods and their symbiotic or mutualistic bacteria, private. ***Tools (most recent):*** GReNaDIne: Data-Driven Approaches to Infer Gene Regulatory Networks in Python. <https://grenadine.readthedocs.io/en/latest/> ***Organization of meetings (most important*):** Joint 10th International Symbiosis Society &amp; 3rd International Conference on Holobionts (Lyon, July 2022); Annual Entomophagous meeting (2017, Lyon); Annual meetings of the Aphid French Network: 2010 and 2012 (Lyon), 2018 (Rennes) and 2022 (Nice); Colloque de Biologie de l’Insecte (16th edition, 2010, Lyon); Lyon’s International Multidisciplinary Meeting on Post-Genomics (5 editions, from 2006 to 2010, Lyon). ***Organization of practical courses:*** « Insect cell cultures », Aphid French Network (Bordeaux, October 2019); « Isolation of aphid bacteriocytes as a platform for transcriptomic analyses », HMicMac ANR grant (May 2017, Lyon); « RNAi in aphids: feeding and injection techniques », Aphid French Network (March 2008, Lyon). ***Ad hoc reviewer for Grant Organizations.*** Western University (Canada); FWO (Belgium); HRZZ (Croatian Science Foundation); CNR (Italy); ANR (France); FranceAgriMer (France); INRAE SPE research grants (France); Research Federation BioEEnViS University of Lyon (France); BQR (Bonus Qualité Recherche) INSA Lyon (France). ***Ad hoc reviewer for journals.*** Apoptosis, Arch. Insect Biochem. Physiol., BMC Biol., BMC Genomics, Cell Death Differ., Cell Rep., Current Biol., Cytom. Part A, Entomol. Exp. Appl., Environ. Microbiome, Eur. J. Entomol., FEMS Microbiol. Ecol., Insect Biochem. Mol. Biol., Insect Mol. Biol., Insect Sci., Insects, Int. J. Mol. Sci., iScience, J. Pest Sci., Microbiome, Microbiol. Spectr., Mol. Ecol., PNAS, Peptides, PlosOne, Sci. Rep., ISME J. ***Member of University selection committees (France).* INSA Lyon**: « Physiology » in 2012, « Insect symbiosis » in 2013, President of the jury « Insect Genomics » in 2015, « Symbiotic network modeling » in 2018, Coordinator of the jury « Microbes and Adaptation » in 2021, « Developmental genetics » in 2021. **University Claude Bernard Lyon1**: « Environmental and molecular microbiology » in 2012, « Plant physiology » in 2017. **University of Dijon:** « Invertebrate physiology » in 2015, **University of Nice**: « Host-Microbes interactions » in 2010 and 2012.

Publications

"gaget-karen"
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Compartmentalized into Bacteriocytes but Highly Invasive: the Puzzling Case of the Co-Obligate Symbiont Serratia symbiotica in the Aphid Periphyllus lyropictus

François Renoz , Mélanie Ribeiro Lopes , Karen Gaget , Gabrielle Duport , Marie-Christine Eloy
Microbiology Spectrum, 2022, ⟨10.1128/spectrum.00457-22⟩
Article dans une revue hal-03704068v1
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Bacteriocyte plasticity in pea aphids facing amino acid stress or starvation during development

Mélanie Ribeiro Lopes , Karen Gaget , François Renoz , Marie-Gabrielle Duport , Severine Balmand
Frontiers in Physiology, 2022, 13, pp.982920. ⟨10.3389/fphys.2022.982920⟩
Article dans une revue hal-04014003v1
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Aphid BCR4 Structure and Activity Uncover a New Defensin Peptide Superfamily

Karine Loth , Nicolas Parisot , Françoise Paquet , Hugo Terrasson , Catherine Sivignon
International Journal of Molecular Sciences, 2022, 23 (20), pp.12480. ⟨10.3390/ijms232012480⟩
Article dans une revue hal-03862651v1

Evolutionary diversification of insulin-related peptides (IRPs) in aphids and spatiotemporal distribution in Acyrthosiphon pisum

C. Huygens , Mélanie Ribeiro Lopes , Karen Gaget , G. Duport , S. Peignier
Insect Biochemistry and Molecular Biology, inPress, 141, pp.103670. ⟨10.1016/j.ibmb.2021.103670⟩
Article dans une revue hal-03507324v1
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Sustainable laser-based technology for insect pest control

R. Gaetani , V. Lacotte , Vincent Dufour , A. Clavel , G. Duport
Scientific Reports, 2021, 11 (1), pp.11068. ⟨10.1038/s41598-021-90782-7⟩
Article dans une revue hal-03239008v1
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Evolutionary novelty in the apoptotic pathway of aphids

Mélanie Ribeiro Lopes , Nicolas Parisot , Karen Gaget , Cissy Huygens , Sergio Peignier
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (51), pp.32545-32556. ⟨10.1073/pnas.2013847117⟩
Article dans une revue hal-03052353v1
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Bis(monoacylglycero)phosphate regulates oxysterol binding protein-related protein 11 dependent sterol trafficking

Maud Arnal-Levron , Yinan Chen , Peter Greimel , Federica Calevro , Karen Gaget
Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 2019, 1864 (9), pp.1247-1257. ⟨10.1016/j.bbalip.2019.05.011⟩
Article dans une revue hal-02146150v1
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Bacteriocyte cell death in the pea aphid/ Buchnera symbiotic system

Pierre Simonet , Karen Gaget , Severine Balmand , Mélanie Ribeiro Lopes , Nicolas Parisot
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (8), pp.E1819 - E1828. ⟨10.1073/pnas.1720237115⟩
Article dans une revue hal-01768487v1
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Bacteriocyte Reprogramming to Cope With Nutritional Stress in a Phloem Sap Feeding Hemipteran, the Pea Aphid Acyrthosiphon pisum

Stefano Colella , Nicolas Parisot , Pierre Simonet , Karen Gaget , Gabrielle Duport
Frontiers in Physiology, 2018, 9, pp.1498. ⟨10.3389/fphys.2018.01498⟩
Article dans une revue hal-01905508v1
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Direct flow cytometry measurements reveal a fine-tuning of symbiotic cell dynamics according to the host developmental needs in aphid symbiosis

Pierre Simonet , Gabrielle Duport , Karen Gaget , Michèle Weiss-Gayet , Stefano Colella
Scientific Reports, 2016, 6, pp.19967. ⟨10.1038/srep19967⟩
Article dans une revue hal-01352561v1
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Disruption of phenylalanine hydroxylase reduces adult lifespan and fecundity, and impairs embryonic development in parthenogenetic pea aphids

Pierre Simonet , Karen Gaget , Nicolas Parisot , Gabrielle Duport , Marjolaine Rey
Scientific Reports, 2016, 6, pp.1-12. ⟨10.1038/srep34321⟩
Article dans une revue hal-01388523v1
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New insight into the RNA interference response against cathepsin-L gene in the pea aphid, Acyrthosiphon pisum: Molting or gut phenotypes specifically induced by injection or feeding treatments.

Panagiotis Sapountzis , Gabrielle Duport , Severine Balmand , Karen Gaget , Stéphanie Jaubert-Possamai
Insect Biochemistry and Molecular Biology, 2014, 51, to be published. ⟨10.1016/j.ibmb.2014.05.005⟩
Article dans une revue hal-01002574v1
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Tyrosine pathway regulation is host-mediated in the pea aphid symbiosis during late embryonic and early larval development

Andréane Rabatel , Gérard Febvay , Karen Gaget , Gabrielle Duport , Patrice Baa-Puyoulet
BMC Genomics, 2013, 14 (1), pp.235. ⟨10.1186/1471-2164-14-235⟩
Article dans une revue hal-00824527v1
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Structure and dynamics of the operon map of Buchnera aphidicola sp. strain APS.

Lilia Brinza , Federica Calevro , Gabrielle Duport , Karen Gaget , Christian Gautier
BMC Genomics, 2010, 11 (666), pp.666. ⟨10.1186/1471-2164-11-666⟩
Article dans une revue hal-00632959v1

Deciphering growth/nutrition dynamics at the aphid – symbiont interface through metabolic modeling

Leo Gerlin , Patrice Baa-Puyoulet , Karen Gaget , Isabelle Rahioui , Marie-Gabrielle Duport
3e Rencontre du Réseau Français de Biologie Adaptative des Pucerons et Organismes Associés (BAPOA), Nov 2023, Villeurbanne, France
Communication dans un congrès hal-04524579v1

Study of host-symbionts coevolution in the whitefly Bemisia tabaci: an experimental evolution approach

Hubert Charles , Hélène Henri , Zainab Belgaidi , Isabelle Rahioui , Karen Gaget
13e Rencontre du Réseau Français de Biologie Adaptative des Pucerons et Organismes Associés (BAPOA), Nov 2023, Villeurbanne, France
Communication dans un congrès hal-04524543v1

Peptides « Bacteriocyte-specific Cysteine Rich » (BCR) : un rôle dans le contrôle de la symbiose ? Focus sur BCR4 chez le puceron du pois

Hugo Terrasson , Karine Loth , Nicolas Parisot , Isabelle Rahioui , Karen Gaget
12. Rencontre du Réseau Français de Biologie Adaptative des Pucerons et Organismes Associés (BAPOA), May 2022, Nice, France
Communication dans un congrès hal-03741305v1

Plasticity of bacteriocytes facing nutritional stresses in the pea aphid development.

Mélanie Ribeiro Lopes , Karen Gaget , François Renoz , Marie-Gabrielle Duport , Severine Balmand
12. Rencontre du Réseau Français de Biologie Adaptative des Pucerons et Organismes Associés (BAPOA), May 2022, Nice, France
Communication dans un congrès hal-03741301v1

Sustainable laser-based technology for insect pest control

R. Gaetani , V. Lacotte , Vincent Dufour , Clavel A. , - Duport, G.
ICESB 2021, Jan 2022, Osaka (visio), Japan
Communication dans un congrès hal-03543644v1

Analysis of the inhibitor of aPoptosis (IAP) repertoire in insects reveals a complex pattern of gene losses and amplifications

Mélanie Ribeiro Lopes , Jousselin Emmanuelle , Patrice Baa-Puyoulet , C. Huygens , Karen Gaget
Incontri di diversità delle forme e degli animali, Università di Pisa, 2021, Pisa, Italy
Communication dans un congrès hal-03514196v1

Analysis of the Inhibitor of aPoptosis (IAP) repertoire in insects reveals a complex pattern of gene losses and amplifications

Mélanie Ribeiro Lopes , Nicolas Parisot , Sergio Peignier , Karen Gaget , Marie-Gabrielle Duport
Webinaires BAPOA 2021, 2021, Villeurbanne (virtual), France
Communication dans un congrès hal-03514209v1

IAP (Inhibitor-of-Apoptosis Protein) gene family expansion and functional diversification in aphids

Mélanie Ribeiro Lopes , Nicolas Parisot , Karen Gaget , Marie-Gabrielle Duport , Abdelaziz Heddi
UK-France joint Meeting Aphid Special Interest Group – BAPOA, Apr 2019, Rothamsted, United Kingdom
Communication dans un congrès hal-03512999v1

Amplification des gènes codant les protéines de la famille des IAP et leur rôle dans l'homéostasie bactériocytaire

Mélanie Ribeiro Lopes , Nicolas Parisot , Karen Gaget , Marie-Gabrielle Duport , Korneel Hens
11. Réunion du Réseau Français de Biologie Adaptative des Pucerons et Organismes Associés (BAPOA), Nov 2018, Rennes, France
Communication dans un congrès hal-03741308v1

Bacteriocyte reprogramming to cope with nutritional stress in a phloem sap feeding hemipteran, the pea aphid Acyrthosiphon pisum

Nicolas Parisot , Mélanie Ribeiro Lopes , Karen Gaget , Marie-Gabrielle Duport , Patrice Baa-Puyoulet
France-Israel PRC Meeting – The role of metabolic interactions in shaping the bacterial endosymbiotic community of Hemyptera, Nov 2018, Villeurbanne, France
Communication dans un congrès hal-03514051v1

Another way to die for bacteriocytes in the aphid/Buchnera symbiotic system

Mélanie Ribeiro Lopes , Pierre Simonet , Karen Gaget , Severine Balmand , Kurt Buhler
Journée des doctorants du département SPE, Jun 2018, Nice, France
Communication dans un congrès hal-03510629v1

Bacteriocyte reprogramming to cope with nutritional stress in a phloem sap feeding hemipteran, the pea aphid Acyrthosiphon pisum

Nicolas Parisot , Stefano Colella , Mélanie Ribeiro Lopes , Karen Gaget , Marie-Gabrielle Duport
International Partner Days, Oct 2018, Villeurbanne (INSA-Lyon), France
Communication dans un congrès hal-03514034v1

Expansion of genes encoding Apoptosis Inhibitor Proteins (IAPs) and their role in a novel bacteriocyte cell death process in aphid symbiosis

Mélanie Ribeiro Lopes , Nicolas Parisot , Karen Gaget , Pierre Simonet , Severine Balmand
22. Evolutionary Biology Meeting, Sep 2018, Marseille, France
Communication dans un congrès hal-03509938v1

A novel cell death process is involved in the elimination of bacteriocytes and their symbionts through aphid aging

Mélanie Ribeiro Lopes , Pierre Simonet , Karen Gaget , Severine Balmand , Nicolas Parisot
France-Israel PRC Meeting – The role of metabolic interactions in shaping the bacterial endosymbiotic community of Hemyptera, Nov 2018, Villeurbanne, France
Communication dans un congrès hal-03514078v1

Rôle clé du bactériocyte dans la résilience du puceron aux stress nutritionnels

Federica Calevro , Nicolas Parisot , Mélanie Ribeiro Lopes , Stefano Colella , Karen Gaget
11ème Réunion du Réseau Français de Biologie Adaptative des Pucerons et Organismes Associés (BAPOA), Nov 2018, Rennes, France
Communication dans un congrès hal-03514026v1

Effecteurs et inhibiteurs de l’apoptose chez le puceron du pois : annotation et implication dans la mort cellulaire bactériocytaire

Mélanie Ribeiro Lopes , Pierre Simonet , Karen Gaget , Marie-Gabrielle Duport , Severine Balmand
10. Réunion du Réseau Français de Biologie Adaptative des Pucerons et Organismes Associés (BAPOA), Nov 2017, Colmar, France
Communication dans un congrès hal-03506807v1

Systems biology of symbiosis: from partners’ genomics to physiology of interactions

Hubert Charles , Federica Calevro , Gérard Febvay , Patrice Baa-Puyoulet , Marie-Gabrielle Duport
First Meeting of the PRC Israel-France, Sep 2016, Villeurbanne, France
Communication dans un congrès hal-03506791v1

Life history traits and tissue-specific gene expression changes underlying the symbiotic pea aphid resilience to a tyrosine and phenylalanine depleted diet

Nicolas Parisot , Pierre Simonet , Karen Gaget , Marie-Gabrielle Duport , Patrice Baa-Puyoulet
9. Réunion du Réseau Français de Biologie Adaptative des Pucerons et Organismes Associés (BAPOA), Nov 2016, Amiens, France
Communication dans un congrès hal-03506796v1

The long-term relationship with Buchnera aphidicola imposes another way to die for Acyrthosiphon pisum bacteriocytes

Pierre Simonet , Severine Balmand , Karen Gaget , Karine Buhler , Nicolas Parisot
9. Réunion annuelle du Réseau BAPOA (Biologie Adaptative des Pucerons et Organismes Associés), Nov 2016, Amiens, France
Communication dans un congrès hal-03506794v1

Une nouvelle forme de mort cellulaire impliquée dans la dégénérescence des cellules bactériocytaires chez le puceron du pois, Acyrthosiphon pisum

Pierre Simonet , Severine Balmand , Karen Gaget , Marie-Gabrielle Duport , Nicolas Parisot
18. Colloque Biologie de l'Insecte, Jun 2016, Tours, France
Communication dans un congrès hal-03506790v1

Coordination des dynamiques cellulaires entre bactériocytes et endosymbiotes au cours du développement des insectes : Une nouvelle approche par cytométrie en flux.

Pierre Simonet , Marie-Gabrielle Duport , Karen Gaget , Michèle Weiss-Gayet , Stefano Colella
Réunion annuelle du REID (Réseau National Ecologie des Interactions Durables), Réseau Ecologie des Interactions Durables (REID). Montferrier/ Lez, FRA., Mar 2015, Villeurbanne, France
Communication dans un congrès hal-02801005v1

Direct flow cytometry measurements and cell imaging reveal a fine-tuning of endosymbiont and bacteriocyte cell dynamics during aphid development

Pierre Simonet , Marie-Gabrielle Duport , Karen Gaget , Severine Balmand , Stefano Colella
UK – France joint meeting on Aphids (Réseau Français de Biologie Adaptative des Pucerons et Organismes Associés – Aphids Special Interest Group of Royal Entomological Sociaty), Nov 2015, Paris, France
Communication dans un congrès hal-03506775v1

Specific body compartment phenotypes induced by dsRNA treatments in the pea aphid: the cathepsin-L and phenylalanine hydroxylase examples

Pierre Simonet , Karen Gaget , Marie-Gabrielle Duport , Federica Calevro
7. Rencontres du réseau Biologie Adaptative des Pucerons et Organismes Associés (BAPOA), Réseau Biologie Adaptative des Pucerons et des Organismes Associés (BAPOA). Le Rheu, FRA., Nov 2014, Avignon, France
Communication dans un congrès hal-02795336v1

Dynamique de la cellule bactériocytaire et des populations symbiotiques au cours du développement du puceron du pois

Pierre Simonet , Marie-Gabrielle Duport , Karen Gaget , M. Weiss-Gayet , Stefano Colella
7èmes journées du Réseau BAPOA (Biologie Adaptative des Pucerons et Organismes Associés), 2014, Avignon, France
Communication dans un congrès hal-03513906v1

Dynamique de la cellule bactériocytaire et des populations symbiotiques au cours du développement du puceron du pois

Pierre Simonet , Marie-Gabrielle Duport , Karen Gaget , Michèle Weiss-Gayet , Stefano Colella
7. Rencontres du réseau Biologie Adaptative des Pucerons et Organismes Associés (BAPOA), Réseau Biologie Adaptative des Pucerons et des Organismes Associés (BAPOA). Le Rheu, FRA., Nov 2014, Avignon, France
Communication dans un congrès hal-02795335v1

dsRNAi in aphids induces variable individual and tissue responses, and phenotypes specific to the administration methods

Panagiotis Sapountzis , Karen Gaget , Marie-Gabrielle Duport , G. Febvay , Hubert Charles
Cycle de séminaires en Biophysique et Biologie Moléculaire de la Cellule et du Développement, Dipartimento di Fisiologia e Biochimica, Università di Pisa / Scuola Normale Superiore di Pisa, Oct 2013, Pisa, Italy
Communication dans un congrès hal-03506764v1

L'inactivation par RNAi du gène codant la phénylalanine hydrolase dans les compartiments symbiotiques provoque une baisse de la fécondité et des défauts de développement chez le puceron du pois, Acyrthosiphon pisum

Karen Gaget , Marie-Gabrielle Duport , Marjolaine Rey , Severine Balmand , Hubert Charles
Réunion du GRREMI (Groupe Régional de Recherche en Microbiologie des Interactions), Oct 2013, Lyon, France
Communication dans un congrès hal-03506724v1

Aphicibles - Symbiosis, digestion and reproduction as aphid physiological processes to identify new targets for insecticides

Yvan Rahbé , Denis Tagu , Guy Condemine , E Guiderdoni , Federica Calevro
ANR - Colloque Plant Genomics 2012, Apr 2012, Pont Royal en Provence, France
Communication dans un congrès hal-03506701v1

Phénotypes induits par l'inactivation fonctionnelle par RNAi du gène ACYPY007803 (phényalanine hydroxylase) chez le puceron du pois

Andréane Rabatel , Marie-Gabrielle Duport , Karen Gaget , Hubert Charles , Gérard Febvay
5. Journées du Réseau BAPOA (Biologie Adaptative des Pucerons et Organismes Associés), Nov 2012, Lyon, France
Communication dans un congrès hal-03506379v1

Integration of metabolic pathways and host regulation in symbiosis: tyrosine and cuticular protein biosynthesis during the pea aphid embryonic development

Andréane Rabatel , Gérard Febvay , Karen Gaget , Gabrielle Duport , Nadia Bendridi
Sixth International Symposium on Molecular Insect Science, 2011, Amsterdam, Netherlands
Communication dans un congrès hal-00748785v1

Transcriptome analysis of embryo development in a parthenogenetic and symbiotic insect model, the pea aphid

Andréane Rabatel , Gérard Febvay , Karen Gaget , Marie-Gabrielle Duport , Yvan Rahbé
IPG'10 Integrative Post-Genomics, Centre Jacques Cartier. Lyon, FRA., Nov 2011, Lyon, France
Communication dans un congrès hal-02814211v1

Genomic analysis of the transport function in the symbiotic system of the pea aphid Acyrthosiphon pisum

Yvan Rahbé , Nicolas Parisot , Karen Gaget , Stefano Colella , Andréane Rabatel
5. Meeting GDRE-RA "Comparative genomics", Institut d'Estudis Catalans (IEC). Barcelona, ESP., Nov 2010, Barcelone, Spain. n. p
Communication dans un congrès hal-02823073v1

Annotation et évolution des familles de transporteurs chez le puceron du pois (Acyrthosiphon pisum)

Nicolas Parisot , Karen Gaget , Stefano Colella , Andréane Rabatel , Federica Calevro
3. Réunion Réseau Français de Biologie Adaptative des Pucerons, Institut National de Recherche Agronomique (INRA). UMR Biologie Fonctionnelle, Insectes et Interactions (0203)., Oct 2010, Lyon, France. n. p
Communication dans un congrès hal-02818835v1

Individual and compartment specific response to RNAi in aphids: each individual matters

Panagiotis Sapountzis , Marie-Gabrielle Duport , Karen Gaget , Severine Balmand , Gérard Febvay
3. Réunion Réseau Français de Biologie Adaptative des Pucerons, Institut National de Recherche Agronomique (INRA). UMR Biologie Fonctionnelle, Insectes et Interactions (0203)., Oct 2010, Lyon, France
Communication dans un congrès hal-02821530v1

Caractérisation transcriptomique du développement embryonnaire et larvaire du puceron du pois Acyrthosiphon pisum

Andréane Rabatel , Gérard Febvay , Karen Gaget , Marie-Gabrielle Duport , Yvan Rahbé
16. Colloque de Biologie de l’Insecte, Oct 2010, Lyon, France. 126 p
Communication dans un congrès hal-02755293v1

Aphicibles : Symbiosis, digestion and reproduction as aphid physiological processes to identify new targets for insecticides

Yvan Rahbé , Denis Tagu , Guy Condemine , Emmanuel Guiderdoni , Federica Calevro
Genoplante 2010, Agence Nationale de la Recherche (ANR). Paris, FRA., Mar 2010, Avignon, France. 40 diapos
Communication dans un congrès hal-02824684v1
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Characterization of partenogenetic embryo development in the context of symbiosis using transcriptome analysis in the pea aphid model

Andréane Rabatel , Gérard Febvay , Karen Gaget , Marie-Gabrielle Duport , Yvan Rahbé
EMBO Workshop on Systems Biology of Development, EMBO. Heidelberg, DEU., Aug 2010, Ascona, Switzerland. 1 p
Communication dans un congrès hal-01231279v1

Extreme plasticity of bacteriocytes facing nutritional stresses during pea aphid development

Mélanie Ribeiro Lopes , Karen Gaget , Marie-Gabrielle Duport , Severine Balmand , Hubert Charles
10. Congress of the International Society of Symbiosis, Jul 2022, Lyon, France
Poster de conférence hal-03741327v1

Bacteriocyte-specific Cystein-Rich (BCR) peptides, a new aphid’s defensin-like family, are promising regulators of aphid symbiosis

Hugo Terrasson , Karine Loth , Nicolas Parisot , Isabelle Rahioui , Karen Gaget
10. Congress of the International Society of Symbiosis, Jul 2022, Lyon, France
Poster de conférence hal-03741331v1

ER stress as a major regulator of aphid bacteriocyte cell death

Karen Gaget , Mélanie Ribeiro Lopes , Marie-Gabrielle Duport , Patrick Callaerts , Nicolas Parisot
12. Rencontre du Réseau Français de Biologie Adaptative des Pucerons et Organismes Associés (BAPOA), May 2022, Nice, France
Poster de conférence hal-03741344v1

Embedded into bacteriocytes, but highly invasive: the puzzling case of the co-obligate symbiont Serratia symbiotica in the aphid Periphyllus lyropictus

François Renoz , Mélanie Ribeiro Lopes , Karen Gaget , Marie-Gabrielle Duport , Marie-Christine Eloy
ELI-Day, May 2022, Louvain-la-Neuve, Belgium
Poster de conférence hal-03741341v1

The role of GPCRs in metabolism and physiology of the pea aphid, Acyrthosiphon pisum

Cissy Huygens , Mélanie Ribeiro Lopes , Karen Gaget , Marie-Gabrielle Duport , Federica Calevro
26.International Congress of Entomology, Jul 2022, Helsinki, Finland
Poster de conférence hal-03741320v1

Bacteriocytes and the interorgan communication network regulating physiology and metabolism of the pea aphid

Cissy Huygens , Mélanie Ribeiro Lopes , Karen Gaget , Marie-Gabrielle Duport , Sergio Peignier
10. Congress of the International Society of Symbiosis, Jul 2022, Lyon, France
Poster de conférence hal-03741324v1

Bacteriocyte reprogramming to maintain organismal homeostasis under nutritional stress in aphid symbiosis

Nicolas Parisot , Stefano Colella , Pierre Simonet , Karen Gaget , Marie-Gabrielle Duport
UK-France joint Meeting Aphid Special Interest Group – BAPOA, Apr 2019, Rothamsted, United Kingdom
Poster de conférence hal-03513048v1

A novel cell death process eliminates both bacteriocytes and their symbionts in the pea aphid/Buchnera symbiotic system

Mélanie Ribeiro Lopes , Pierre Simonet , Karen Gaget , Severine Balmand , Nicolas Parisot
UK-France joint Meeting Aphid Special Interest Group – BAPOA, Apr 2019, Rothamsted, United Kingdom
Poster de conférence hal-03513018v1

Bacteriocyte reprogramming to cope with nutritional stress in a phloem sap feeding hemipteran, the pea aphid Acyrthosiphon pisum

Nicolas Parisot , Mélanie Ribeiro Lopes , Karen Gaget , Marie-Gabrielle Duport , Patrice Baa-Puyoulet
UK-France joint Meeting Aphid Special Interest Group – BAPOA, Apr 2019, Harpenden, United Kingdom
Poster de conférence hal-03741333v1

Bacteriocyte reprogramming to maintain organismal homeostasis under nutritional stress in aphid symbiosis

Nicolas Parisot , Stefano Colella , Pierre Simonet , Karen Gaget , Marie-Gabrielle Duport
XIth European Congress of Entomology, Jul 2018, Naples, Italy
Poster de conférence hal-03509885v1

A novel cell death process eliminates both bacteriocytes and their symbionts in the pea aphid/Buchnera symbiotic system

Mélanie Ribeiro Lopes , Pierre Simonet , Karen Gaget , Severine Balmand , Nicolas Parisot
International Partner Days, Oct 2018, Villeurbanne (INSA-Lyon), France
Poster de conférence hal-03514067v1

Molecular characterization of aphid bacteriocyte cell death by RNAseq analysis

Mélanie Ribeiro Lopes , Nicolas Parisot , Karen Gaget , Patrick Callaerts , Federica Calevro
International Partner Days, Oct 2018, Lyon, France
Poster de conférence hal-03741347v1

A novel cell death process eliminates both bacteriocytes and their symbionts in the pea aphid/Buchnera symbiotic system

Mélanie Ribeiro Lopes , Pierre Simonet , Karen Gaget , Severine Balmand , Nicolas Parisot
11. European Congress of Entomology, Jul 2018, Naples, Italy
Poster de conférence hal-03509913v1

Molecular characterization of aphid bacteriocyte cell death by RNAseq analysis

Mélanie Ribeiro Lopes , Nicolas Parisot , Karen Gaget , Patrick Callaerts , Federica Calevro
11. European Congress of Entomology, Jul 2018, Naples, Italy
Poster de conférence hal-03741337v1

A novel cell death process eliminates both bacteriocytes and their symbionts in the pea aphid/Buchnera symbiotic system

Mélanie Ribeiro Lopes , Nicolas Parisot , Karen Gaget , Patrick Callaerts , Federica Calevro
International Partner Days, Oct 2018, Lyon, France
Poster de conférence hal-03741354v1

Cathepsin-L proteinase is involved in cuticle remodeling during the molting process in the pea aphid, Acyrthosiphon pisum

Pierre Simonet , Panagiotis Sapountzis , Marie-Gabrielle Duport , Severine Balmand , Karen Gaget
7. International Symposium on Molecular Insect Science, Jul 2014, Amsterdam, Netherlands. , 1 p., 2014
Poster de conférence hal-02797200v1
Image document

Tyrosine metabolism and parthenogenetic development in a symbiotic insect, the pea aphid: the central function of phenylalanine hydroxylase

Pierre Simonet , Karen Gaget , Marjolaine Rey , Marie-Gabrielle Duport , Hubert Charles
7. International Symposium on Molecular Insect Science, Jul 2014, Amsterdam, Netherlands. 1 p., 2014
Poster de conférence hal-02792558v1

Métabolisme de la tyrosine et développement parthénogénétique chez le puceron du pois : la fonction centrale de la phenylalanine hydroxylase

Pierre Simonet , Karen Gaget , Marjolaine Rey , Marie-Gabrielle Duport , Hubert Charles
7. Rencontres du réseau Biologie Adaptative des Pucerons et Organismes Associés (BAPOA), Nov 2014, Avignon, France. 2014
Poster de conférence hal-02795333v1

Implication de la cathepsine-L dans le remodelage cuticulaire durant le processus de mue chez le puceron du pois, Acyrthosiphon pisum

Pierre Simonet , Panagiotis Sapountzis , Marie-Gabrielle Duport , Severine Balmand , Karen Gaget
7. Rencontres du réseau Biologie Adaptative des Pucerons et Organismes Associés (BAPOA), Nov 2014, Avignon, France. 2014
Poster de conférence hal-02795332v1

Diminution de fécondité et défauts de développement induits par l’inactivation fonctionnelle par RNAi du gène codant la phénylalanine hydroxylase chez le puceron du pois, Acyrthosiphon

Karen Gaget , Marie-Gabrielle Duport , Marjolaine Rey , Severine Balmand , Hubert Charles
17. Colloque de Biologie de l’Insecte - CBI-2013, Oct 2013, Montpellier, France
Poster de conférence hal-03506719v1

Phenotypic effects of ACYPI007803 knockdown by RNAi in the pea aphid

Andréane Rabatel , Karen Gaget , Marie-Gabrielle Duport , Hubert Charles , Gérard Febvay
8. Meeting of the International Aphid Genomics Consortium., Jan 2013, Harpenden, United Kingdom
Poster de conférence hal-03506744v1

Integration of metabolic pathways and host regulation in symbiosis: tyrosine and cuticular protein biosynthesis during the pea aphid embryonic development

Andréane Rabatel , Gérard Febvay , Karen Gaget , Marie-Gabrielle Duport , Nadia Bendridi
4. Réunion Réseau BAPOA, Nov 2011, Paris, France. 1 p., 2011
Poster de conférence hal-02805925v1

Integration of metabolic pathways and host regulation in symbiosis: tyrosine and cuticular protein biosynthesis during the pea aphid embryonic development

Andréane Rabatel , Gérard Febvay , Karen Gaget , Marie-Gabrielle Duport , Nadia Bendridi
6. International Symposium on Molecular Insect Science, Oct 2011, Amsterdam, Netherlands. Elsevier, 2011,  
Poster de conférence hal-02747829v1

Single insect and tissue compartment specific response to RNAi microinjection in aphids: each individual matters

Panagiotis Sapountzis , Marie-Gabrielle Duport , Karen Gaget , Thomas Horn , Michael Boutros
4. Annual Arthropod Genomics Symposium on “Arthropod Genomics: New Approaches and Outcomes”, Jun 2010, Kansas City, United States. 1 p., 2010
Poster de conférence hal-02820936v1

Réponse tissu-spécifique au traitement par RNAi chez le puceron du pois : une étude cinétique à l’échelle de l’individu

Panagiotis Sapountzis , Marie-Gabrielle Duport , Karen Gaget , Severine Balmand , Stéphanie Jaubert-Possamai
16. Colloque de Biologie de l’Insecte, Oct 2010, Lyon, France. , 126 p., 2010, CB-2010 : 16ème Colloque de Biologie de l'Insecte, Lyon, 18 au 20 octobre 2010
Poster de conférence hal-02755004v1

Analyse génomique de la fonction de transport dans le système symbiotique du puceron du pois Acyrthosiphon pisum

Nicolas Parisot , Karen Gaget , Stefano Colella , Andréane Rabatel , Federica Calevro
16. Colloque de Biologie de l’Insecte, Oct 2010, Lyon, France. , 126 p., 2010, CBI-2010 : 16ème Colloque de Biologie de l’Insecte, Lyon, 18 au 20 octobre 2010
Poster de conférence hal-02755294v1