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Number of documents

44

Fabien Pierrel


Journal articles43 documents

  • Arthur Burgardt, Ludovic Pelosi, Mahmoud Hajj Chehade, Volker Wendisch, Fabien Pierrel. Rational Engineering of Non-Ubiquinone Containing Corynebacterium glutamicum for Enhanced Coenzyme Q10 Production. Metabolites, MDPI, 2022, 12 (5), pp.428. ⟨10.3390/metabo12050428⟩. ⟨hal-03677651⟩
  • Rodrigo Arias-Cartin, Alexandre Uzel, Farida Seduk, Guillaume Gerbaud, Fabien Pierrel, et al.. Identification and characterization of a non-canonical menaquinone-linked formate dehydrogenase. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2022, pp.101384. ⟨10.1016/j.jbc.2021.101384⟩. ⟨hal-03431446⟩
  • Fabien Pierrel, Arthur Burgardt, Jin-Ho Lee, Ludovic Pelosi, Volker Wendisch. Recent advances in the metabolic pathways and microbial production of coenzyme Q. World Journal of Microbiology and Biotechnology, Springer Verlag, 2022, 38 (4), pp.58. ⟨10.1007/s11274-022-03242-3⟩. ⟨hal-03677653⟩
  • Sheena Dass, Serena Shunmugam, Laurence Berry, Christophe-Sebastien Arnold, Nicholas Katris, et al.. Toxoplasma LIPIN is essential in channeling host lipid fluxes through membrane biogenesis and lipid storage. Nature Communications, Nature Publishing Group, 2021, 12, pp.2813. ⟨10.1038/s41467-021-22956-w⟩. ⟨hal-03456819⟩
  • Katayoun Kazemzadeh, Mahmoud Hajj Chehade, Gautier Hourdoir, Camille Dorothée Brunet, Yvan Caspar, et al.. The biosynthetic pathway of ubiquinone contributes to pathogenicity of Francisella Running title: Ubiquinone and Francisella pathogenicity. Journal of Bacteriology, American Society for Microbiology, 2021, ⟨10.1128/JB.00400-21⟩. ⟨hal-03357541⟩
  • Julie Szyttenholm, Florence Chaspoul, Marielle Bauzan, Anne-Lise Ducluzeau, Mahmoud Hajj Chehade, et al.. The controversy on the ancestral arsenite oxidizing enzyme; deducing evolutionary histories with phylogeny and thermodynamics. Biochimica biophysica acta (BBA) - Bioenergetics, Elsevier, 2020, 1861 (10), pp.148252. ⟨10.1016/j.bbabio.2020.148252⟩. ⟨hal-02896357⟩
  • Cinzia Fino, Martin Vestergaard, Hanne Ingmer, Fabien Pierrel, Kenn Gerdes, et al.. PasT of Escherichia coli sustains antibiotic tolerance and aerobic respiration as a bacterial homolog of mitochondrial Coq10. MicrobiologyOpen, Wiley, 2020, ⟨10.1002/mbo3.1064⟩. ⟨hal-02896344⟩
  • Sophie S. Abby, Katayoun Kazemzadeh, Charles Vragniau, Ludovic Pelosi, Fabien Pierrel. Advances in bacterial pathways for the biosynthesis of ubiquinone. Biochimica biophysica acta (BBA) - Bioenergetics, Elsevier, 2020, 1861 (11), pp.148259. ⟨10.1016/j.bbabio.2020.148259⟩. ⟨hal-02944115⟩
  • Chau-Duy-Tam Vo, Julie Michaud, Sylvie Elsen, Bruno Faivre, Emmanuelle Bouveret, et al.. The O2-independent pathway of ubiquinone biosynthesis is essential for denitrification in Pseudomonas aeruginosa. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2020, 295 (27), pp.9021-9032. ⟨10.1074/jbc.RA120.013748⟩. ⟨pasteur-02746713⟩
  • Ludovic Pelosi, Chau-Duy-Tam Vo, Sophie Saphia Abby, Laurent Loiseau, Bérengère Rascalou, et al.. Ubiquinone Biosynthesis over the Entire O2 Range: Characterization of a Conserved O2-Independent Pathway. mBio, American Society for Microbiology, 2019, 10 (4), ⟨10.1128/mBio.01319-19⟩. ⟨hal-02183791⟩
  • Manuel Acosta Lopez, Eva Trevisson, Marcella Canton, Luis Vazquez-Fonseca, Valeria Morbidoni, et al.. Vanillic Acid Restores Coenzyme Q Biosynthesis and ATP Production in Human Cells Lacking COQ6. Oxidative Medicine and Cellular Longevity, Hindawi, 2019, 2019, pp.1-11. ⟨10.1155/2019/3904905⟩. ⟨hal-02323996⟩
  • Cristina Cerqua, Alberto Casarin, Fabien Pierrel, Luis Vazquez Fonseca, Giampiero Viola, et al.. Vitamin K2 cannot substitute Coenzyme Q10 as electron carrier in the mitochondrial respiratory chain of mammalian cells. Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-43014-y⟩. ⟨hal-02324041⟩
  • Mahmoud Hajj Chehade, Ludovic Pelosi, Cameron David Fyfe, Laurent Loiseau, Bérengère Rascalou, et al.. A Soluble Metabolon Synthesizes the Isoprenoid Lipid Ubiquinone. Cell Chemical Biology, Cell Press, 2019, 26 (4), pp.482-492.e7. ⟨10.1016/j.chembiol.2018.12.001⟩. ⟨hal-02071798⟩
  • Maria Andrea Desbats, Valeria Morbidoni, Micol Silic-Benussi, Mara Doimo, Vincenzo Ciminale, et al.. The COQ2 genotype predicts the severity of coenzyme Q 10 deficiency. Human Molecular Genetics, Oxford University Press (OUP), 2017, 25 (19), pp.4256 - 4265. ⟨10.1093/hmg/ddw257⟩. ⟨hal-01635280⟩
  • Fabien Pierrel. Impact of Chemical Analogs of 4-Hydroxybenzoic Acid on Coenzyme Q Biosynthesis: From Inhibition to Bypass of Coenzyme Q Deficiency. Frontiers in Physiology, Frontiers, 2017, 87, pp.80 - 80. ⟨10.3389/fphys.2017.00436⟩. ⟨hal-01583835⟩
  • Laurent Loiseau, Cameron Fyfe, Laurent Aussel, Mahmoud Hajj Chehade, Sara B. Hernández, et al.. The UbiK protein is an accessory factor necessary for bacterial ubiquinone (UQ) biosynthesis and forms a complex with the UQ biogenesis factor UbiJ. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2017, 292 (28), pp.11937 - 11950. ⟨10.1074/jbc.M117.789164⟩. ⟨hal-01615493⟩
  • Alexandre Ismail, Vincent Leroux, Myriam Smadja, Lucie Gonzalez, Murielle Lombard, et al.. Coenzyme Q Biosynthesis: Evidence for a Substrate Access Channel in the FAD-Dependent Monooxygenase Coq6. PLoS Computational Biology, Public Library of Science, 2016, 12 (1), pp.e1004690. ⟨10.1371/journal.pcbi.1004690⟩. ⟨hal-01424489⟩
  • Laurie-Anne Payet, Mélanie Leroux, John  C. Willison, Akio Kihara, Ludovic Pelosi, et al.. Mechanistic Details of Early Steps in Coenzyme Q Biosynthesis Pathway in Yeast. Cell Chemical Biology, Cell Press, 2016, 23 (10), pp.1241 - 1250. ⟨10.1016/j.chembiol.2016.08.008⟩. ⟨hal-01424510⟩
  • Ludovic Pelosi, Anne-Lise Ducluzeau, Laurent Loiseau, Frédéric Barras, Dominique Schneider, et al.. Evolution of Ubiquinone Biosynthesis: Multiple Proteobacterial Enzymes with Various Regioselectivities To Catalyze Three Contiguous Aromatic Hydroxylation Reactions. mSystems, 2016, 1 (4), pp.00091-16. ⟨10.1128/mSystems.00091-16⟩. ⟨hal-01424513⟩
  • Jonathan a. Stefely, Floriana Licitra, Leila Laredj, Andrew g. Reidenbach, Zachary a. Kemmerer, et al.. Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity. Molecular Cell, Cell Press, 2016, 63 (4), pp.608 - 620. ⟨10.1016/j.molcel.2016.06.030⟩. ⟨hal-01424495⟩
  • Julia Rendon, Eric Pilet, Zeinab Fahs, Farida Seduk, Léa Sylvi, et al.. Demethylmenaquinol is a substrate of Escherichia coli nitrate reductase A (NarGHI) and forms a stable semiquinone intermediate at the NarGHI quinol oxidation site. Biochimica biophysica acta (BBA) - Bioenergetics, Elsevier, 2015, 1847 (8), pp.739-747. ⟨10.1016/j.bbabio.2015.05.001⟩. ⟨hal-01429032⟩
  • Mohammad Ozeir, Ludovic Pelosi, Alexandre Ismail, Caroline Mellot-Draznieks, Marc Fontecave, et al.. Coq6 Is Responsible for the C4-deamination Reaction in Coenzyme Q Biosynthesis in Saccharomyces cerevisiae *. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2015, ⟨10.1074/jbc.M115.675744⟩. ⟨hal-01424487⟩
  • Laurent Aussel, Fabien Pierrel, Laurent Loiseau, Murielle Lombard, Marc Fontecave, et al.. Biosynthesis and physiology of coenzyme Q in bacteria.. Biochimica biophysica acta (BBA) - Bioenergetics, Elsevier, 2014, 1837 (7), pp.1004-1011. ⟨10.1016/j.bbabio.2014.01.015⟩. ⟨hal-01077983⟩
  • Laurent Aussel, Laurent Loiseau, Mahmoud Hajj Chehade, Bérengère Pocachard, Marc Fontecave, et al.. ubiJ, a New Gene Required for Aerobic Growth and Proliferation in Macrophage, Is Involved in Coenzyme Q Biosynthesis in Escherichia coli and Salmonella enterica Serovar Typhimurium.. Journal of Bacteriology, American Society for Microbiology, 2014, 196 (1), pp.70-79. ⟨10.1128/JB.01065-13⟩. ⟨hal-00917119⟩
  • Xavier Brazzolotto, Fabien Pierrel, Ludovic Pelosi. Three conserved histidyl residues contribute to mitochondrial iron transport through mitoferrins.. Biochemical Journal, Portland Press, 2014, 460 (1), pp.79-89. ⟨10.1042/BJ20140107⟩. ⟨hal-00961552⟩
  • Mahmoud Hajj Chehade, Laurent Loiseau, Murielle Lombard, Ludovic Pecqueur, Alexandre Ismail, et al.. A new gene involved in coenzyme Q biosynthesis in Escherichia coli: UbiI functions in aerobic C5-hydroxylation. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2013, 288 (27), pp.20085-92. ⟨10.1074/jbc.M113.480368⟩. ⟨hal-00904907⟩
  • Mara Doimo, Eva Trevisson, Rannar Airik, Marc Bergdoll, Carlos Santos-Ocaña, et al.. Effect of vanillic acid on COQ6 mutants identified in patients with coenzyme Q10 deficiency.. BBA - Biochimica et Biophysica Acta, Elsevier, 2013, 1842 (1), pp.1-6. ⟨10.1016/j.bbadis.2013.10.007⟩. ⟨hal-00904926⟩
  • Letian X Xie, Mohammad Ozeir, Jeniffer y Tang, Jia y Chen, Sylvie-Kieffer Jaquinod, et al.. Overexpression of the Coq8 kinase in Saccharomyces cerevisiae coq null mutants allows for accumulation of diagnostic intermediates of the coenzyme Q6 biosynthetic pathway.. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2012, 287 (28), pp.23571-81. ⟨10.1074/jbc.M112.360354⟩. ⟨hal-00904902⟩
  • Mohammad Ozeir Ozeir, Letian X. Xie, Mahmoud Hajj Chehade, Jeniffer Y. Tang, Sylvie-Kieffer Jacquinod, et al.. In vivo accumulation of coenzyme Q biosynthetic intermediates and aminated analogs in the yeast Saccharomyces cerevisiae. Biochimica biophysica acta (BBA) - Bioenergetics, Elsevier, 2012, 1817, pp.S92-S92. ⟨10.1016/j.bbabio.2012.06.249⟩. ⟨hal-01236935⟩
  • Mohammad Ozeir, Ulrich Mühlenhoff, Holger Webert, Roland Lill, Marc Fontecave, et al.. Coenzyme q biosynthesis: coq6 is required for the c5-hydroxylation reaction and substrate analogs rescue coq6 deficiency.. Chem Biol, 2011, 18 (9), pp.1134-42. ⟨10.1016/j.chembiol.2011.07.008⟩. ⟨hal-00630764⟩
  • Fabien Pierrel, Olivier Hamelin, Thierry Douki, Sylvie Kieffer-Jaquinod, Ulrich Mühlenhoff, et al.. Involvement of mitochondrial ferredoxin and para-aminobenzoic acid in yeast coenzyme Q biosynthesis.: pABA is a precursor of yeast coenzyme Q. Chem Biol, 2010, 17 (5), pp.449-59. ⟨10.1016/j.chembiol.2010.03.014⟩. ⟨hal-00497916⟩
  • Ulrich Mühlenhoff, Sabine Molik, José R Godoy, Marta A Uzarska, Nadine Richter, et al.. Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur cluster.. Cell Metab, 2010, 12 (4), pp.373-85. ⟨10.1016/j.cmet.2010.08.001⟩. ⟨hal-00630763⟩
  • Megan Bestwick, Oleh Khalimonchuk, Fabien Pierrel, Dennis R Winge. The role of Coa2 in hemylation of yeast Cox1 revealed by its genetic interaction with Cox10.. Molecular and Cellular Biology, American Society for Microbiology, 2010, 30 (1), pp.172-85. ⟨10.1128/MCB.00869-09⟩. ⟨hal-00497920⟩
  • Oleh Khalimonchuk, Kevin Rigby, Megan Bestwick, Fabien Pierrel, Paul A Cobine, et al.. Pet191 is a cytochrome c oxidase assembly factor in Saccharomyces cerevisiae.. Eukaryotic Cell, American Society for Microbiology, 2008, 7 (8), pp.1427-31. ⟨10.1128/EC.00132-08⟩. ⟨hal-00375432⟩
  • Marjatta Son, Scot C Leary, Nadine Romain, Fabien Pierrel, Dennis R Winge, et al.. Isolated cytochrome c oxidase deficiency in G93A SOD1 mice overexpressing CCS protein.. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2008, 283 (18), pp.12267-75. ⟨10.1074/jbc.M708523200⟩. ⟨hal-00376153⟩
  • Fabien Pierrel, Oleh Khalimonchuk, Paul A Cobine, Megan Bestwick, Dennis R Winge. Coa2 is an assembly factor for yeast cytochrome c oxidase biogenesis that facilitates the maturation of Cox1.. Molecular and Cellular Biology, American Society for Microbiology, 2008, 28 (16), pp.4927-39. ⟨10.1128/MCB.00057-08⟩. ⟨hal-00375430⟩
  • Fabien Pierrel, Megan L Bestwick, Paul A Cobine, Oleh Khalimonchuk, Julia A Cricco, et al.. Coa1 links the Mss51 post-translational function to Cox1 cofactor insertion in cytochrome c oxidase assembly.. EMBO Journal, EMBO Press, 2007, 26 (20), pp.4335-46. ⟨10.1038/sj.emboj.7601861⟩. ⟨hal-00374057⟩
  • Fabien Pierrel, Paul A Cobine, Dennis R Winge. Metal Ion availability in mitochondria.. BioMetals, Springer Verlag, 2007, 20 (3-4), pp.675-82. ⟨10.1007/s10534-006-9052-9⟩. ⟨hal-00375433⟩
  • Carole Mathevon, Fabien Pierrel, Jean-Louis Oddou, Ricardo Garcia-Serres, Geneviève Blondin, et al.. tRNA-modifying MiaE protein from Salmonella typhimurium is a nonheme diiron monooxygenase.. Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2007, 104 (33), pp.13295-300. ⟨10.1073/pnas.0704338104⟩. ⟨hal-01069738⟩
  • Heather L. Hernandez, Fabien Pierrel, Eric Elleingand, Ricardo Garcia-Serres, Boi Hanh Huynh, et al.. MiaB, a bifunctional radical-S-adenosylmethionine enzyme involved in the thiolation and methylation of tRNA, contains two essential [4Fe-4S] clusters.. Biochemistry, American Chemical Society, 2007, 46, pp.5140-5147. ⟨hal-00377635⟩
  • Paul A Cobine, Fabien Pierrel, Scot C Leary, Florin Sasarman, Yih-Chern Horng, et al.. The P174L mutation in human Sco1 severely compromises Cox17-dependent metallation but does not impair copper binding.. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2006, 281 (18), pp.12270-6. ⟨10.1074/jbc.M600496200⟩. ⟨hal-00376137⟩
  • Paul A Cobine, Fabien Pierrel, Dennis R Winge. Copper trafficking to the mitochondrion and assembly of copper metalloenzymes.. Biochimica et Biophysica Acta - Molecular Cell Research, Elsevier, 2006, 1763 (7), pp.759-72. ⟨10.1016/j.bbamcr.2006.03.002⟩. ⟨hal-00376149⟩
  • Paul A Cobine, Fabien Pierrel, Megan L Bestwick, Dennis R Winge. Mitochondrial matrix copper complex used in metallation of cytochrome oxidase and superoxide dismutase.. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2006, 281 (48), pp.36552-9. ⟨10.1074/jbc.M606839200⟩. ⟨hal-00376121⟩

Preprints, Working Papers, ...1 document

  • Pawan Kumar Saini, Hannah Dawitz, Andreas Aufschnaiter, Jinsu Thomas, Amélie Amblard, et al.. The [PSI+] prion and HSP104 modulate cytochrome c oxidase deficiency caused by deletion of COX12. 2021. ⟨hal-03402829⟩