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Fabien Crauste

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Présentation

Directeur de Recherches CNRS (depuis 2019) - Section 41 & CID 51 Chargé de Recherches CNRS (2006 - 2019) - Section 41 & CID 51 Directeur du [Réseau Thématique Math Bio Santé](https://math-bio-sante.math.cnrs.fr/), 2024 Directeur du [GDR MathSAV](https://mathsav.math.cnrs.fr/) (Mathématiques, Santé, Sciences de la Vie), 2022 - 2023 Affiliation (2020 - ...) : Laboratoire MAP5 UMR 8145, Université Paris Cité, Paris Affiliation (2018 - 2020) : Institut de Mathématiques de Bordeaux UMR 5251, Université de Bordeaux, Bordeaux Affiliation (2006 - 2018) : Institut Camille Jordan UMR 5208, Université de Lyon, Lyon Affiliation (2011 - 2018) : Equipe projet Inria DRACULA, Centre Inria Grenoble Rhône Alpes, Lyon

Publications

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Stochastic modeling of a gene regulatory network driving B cell development in germinal centers

Alexey Koshkin , Ulysse Herbach , María Rodríguez Martínez , Olivier Gandrillon , Fabien Crauste
PLoS ONE, 2024, 19 (3), pp.e0301022. ⟨10.1371/journal.pone.0301022⟩
Article dans une revue hal-04490302v3
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CD8 memory precursor cell generation is a continuous process

Helena Todorov , Margaux Prieux , Daphne Laubreton , Matteo Bouvier , Shaoying Wang
iScience, 2022, 25 (9), pp.104927. ⟨10.1016/j.isci.2022.104927⟩
Article dans une revue hal-03842898v1
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Multiscale Modeling of Germinal Center Recapitulates the Temporal Transition From Memory B Cells to Plasma Cells Differentiation as Regulated by Antigen Affinity-Based Tfh Cell Help

Elena Merino Tejero , Danial Lashgari , Rodrigo García-Valiente , Xuefeng Gao , Fabien Crauste
Frontiers in Immunology, 2021, 11, ⟨10.3389/fimmu.2020.620716⟩
Article dans une revue hal-03153711v1
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Modeling and characterization of inter-individual variability in CD8 T cell responses in mice

Chloe Audebert , Daphné Laubreton , Christophe Arpin , Olivier Gandrillon , Jacqueline Marvel
In Silico Biology, 2021, 14 (1-2), pp.13-39. ⟨10.3233/ISB-200205⟩
Article dans une revue hal-03136073v1
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Practical identifiability in the frame of nonlinear mixed effects models: the example of the in vitro erythropoiesis

Ronan Duchesne , Anissa Guillemin , Olivier Gandrillon , Fabien Crauste
BMC Bioinformatics, 2021, pp.1-21. ⟨10.1186/s12859-021-04373-4⟩
Article dans une revue hal-03364480v1
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A model for establishment, maintenance and reactivation of the immune response after vaccination against Ebola virus

Irene Balelli , Chloé Pasin , Mélanie Prague , Fabien Crauste , Thierry van Effelterre
Journal of Theoretical Biology, 2020, 495, pp.110254. ⟨10.1016/j.jtbi.2020.110254⟩
Article dans une revue hal-03160892v2
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Model-based assessment of the Role of Uneven Partitioning of Molecular Content on Heterogeneity and Regulation of Differentiation in CD8 T-cell Immune Responses

Simon Girel , Christophe Arpin , Jacqueline Marvel , Olivier Gandrillon , Fabien Crauste
Frontiers in Immunology, inPress, pp.1-41. ⟨10.3389/fimmu.2019.00230⟩
Article dans une revue hal-02008705v1
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Drugs modulating stochastic gene expression affect the erythroid differentiation process

Anissa Guillemin , Ronan Duchesne , Fabien Crauste , Sandrine Gonin-Giraud , Olivier Gandrillon
PLoS ONE, 2019, 14 (11), pp.1-19. ⟨10.1371/journal.pone.0225166⟩
Article dans une revue hal-02375801v1

Calibration, Selection and Identifiability Analysis of a Mathematical Model of the in vitro Erythropoiesis in Normal and Perturbed Contexts

Ronan Duchesne , Anissa Guillemin , Fabien Crauste , Olivier Gandrillon
In Silico Biology, 2019, 13 (1-2), pp.55-69. ⟨10.3233/ISB-190471⟩
Article dans une revue hal-02309925v1
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Oscillations and asymptotic convergence for a delay differential equation modeling platelet production

Loïs Boullu , Mostafa Adimy , Fabien Crauste , Laurent Pujo-Menjouet
Discrete and Continuous Dynamical Systems - Series B, 2019, 24 (6), pp.2417-2442. ⟨10.3934/dcdsb.2018259⟩
Article dans une revue hal-01835435v2

A multiscale model of the CD8 T cell immune response structured by intracellular content

Loic Barbarroux , Philippe Michel , Mostafa Adimy , Fabien Crauste
Discrete and Continuous Dynamical Systems - Series B, 2018, 23 (9), pp.3969-4002. ⟨10.3934/dcdsb.2018120⟩
Article dans une revue hal-01969237v1
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Investigating the role of the experimental protocol in phenylhydrazine-induced anemia on mice recovery

Oscar Angulo , Olivier Gandrillon , Fabien Crauste
Journal of Theoretical Biology, 2018, 437, pp.286 - 298. ⟨10.1016/j.jtbi.2017.10.031⟩
Article dans une revue hal-01646792v1
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Existence and stability of periodic solutions of an impulsive differential equation and application to CD8 T-cell differentiation

Simon Girel , Fabien Crauste
Journal of Mathematical Biology, 2018, 76 (7), pp.1765-1795. ⟨10.1007/s00285-018-1220-3⟩
Article dans une revue hal-01721728v1
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Numerical integration of an erythropoiesis model with explicit growth factor dynamics

Oscar Angulo , Fabien Crauste , Juan Carlos López-Marcos
Journal of Computational and Applied Mathematics, 2018, 330, pp.770 - 782. ⟨10.1016/j.cam.2017.01.033⟩
Article dans une revue hal-01646786v1

Identification of Nascent Memory CD8 T Cells and Modeling of Their Ontogeny

Fabien Crauste , Julien Mafille , Lilia Boucinha , Sophia Djebali , Olivier Gandrillon
Cell Systems, 2017, 4 (3), pp.306-317. ⟨10.1016/j.cels.2017.01.014⟩
Article dans une revue hal-01409637v1
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IL-2 sensitivity and exogenous IL-2 concentration gradient tune the productive contact duration of CD8+ T cell-APC: a multiscale modeling study

Xuefeng Gao , Christophe Arpin , Jacqueline Marvel , Sotiris A. Prokopiou , Olivier Gandrillon
BMC Systems Biology, 2016, 10 (1), pp.77. ⟨10.1186/s12918-016-0323-y⟩
Article dans une revue inserm-01354185v1
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Predicting pathogen-specific CD8 T cell immune responses from a modeling approach.

Fabien Crauste , Emmanuelle Terry , I Le Mercier , Julien Mafille , Sophie Djebali
Journal of Theoretical Biology, 2015, 374, pp.66-82. ⟨10.1016/j.jtbi.2015.03.033⟩
Article dans une revue hal-00717406v2
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Optimal linear stability condition for scalar differential equations with distributed delay

Samuel Bernard , Fabien Crauste
Discrete and Continuous Dynamical Systems - Series B, 2015, 20 (7), ⟨10.3934/dcdsb.2015.20.1855⟩
Article dans une revue hal-00997528v1
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A mathematical model of leptin resistance

Marine Jacquier , Hédi A. Soula , Fabien Crauste
Mathematical Biosciences, 2015, 267, ⟨10.1016/j.mbs.2015.06.008⟩
Article dans une revue hal-01233483v1

Multiscale Modeling of the Early CD8 T-Cell Immune Response in Lymph Nodes: An Integrative Study

Sotiris Prokopiou , Loic Barbarroux , Samuel Bernard , Julien Mafille , Yann Leverrier
Computation, 2014, 2 (4), pp.159-181. ⟨10.3390/computation2040159⟩
Article dans une revue hal-01074736v1
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A predictive model of the dynamics of body weight and food intake in rats submitted to caloric restrictions.

Marine Jacquier , Fabien Crauste , Christophe Soulage , Hédi A Soula
PLoS ONE, 2014, 9 (6), pp.e100073. ⟨10.1371/journal.pone.0100073⟩
Article dans une revue hal-01017357v1

Delay Differential Equations and Autonomous Oscillations in Hematopoietic Stem Cell Dynamics Modeling

Mostafa Adimy , Fabien Crauste
Mathematical Modelling of Natural Phenomena, 2012, 7 (6), pp.1-22. ⟨10.1051/mmnp/20127601⟩
Article dans une revue hal-00766339v1

Mathematical model of the primary CD8 T cell immune response: stability analysis of a nonlinear age-structured system.

Emmanuelle Terry , Jacqueline Marvel , Christophe Arpin , Olivier Gandrillon , Fabien Crauste
Journal of Mathematical Biology, 2012, 65, pp.263-291. ⟨10.1007/s00285-011-0459-8⟩
Article dans une revue hal-00649219v1
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Modeling erythroblastic islands: using a hybrid model to assess the function of central macrophage.

S. Fischer , P. Kurbatova , N. Bessonov , Olivier Gandrillon , Vitaly Volpert
Journal of Theoretical Biology, 2012, 298, pp.92-106. ⟨10.1016/j.jtbi.2012.01.002⟩
Article dans une revue hal-00596682v2
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A review on local asymptotic stability analysis for mathematical models of hematopoiesis with delay and delay-dependent coefficients

Fabien Crauste
Annals of the Tiberiu Popoviciu Seminar of functional equations, approximation and convexity, 2011, 9, pp.121-143
Article dans une revue hal-00750271v1

Modelling of Plant Growth with Apical or Basal Meristem

Nikolai Bessonov , Fabien Crauste , Vitaly Volpert
Mathematical Modelling of Natural Phenomena, 2011, 6 (2), pp.107-132. ⟨10.1051/mmnp/20116204⟩
Article dans une revue hal-00649218v1
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HYBRID MODEL OF ERYTHROPOIESIS AND LEUKEMIA TREATMENT WITH CYTOSINE ARABINOSIDE

Polina Kurbatova , Samuel Bernard , Nikolai Bessonov , Fabien Crauste , Ivan Demin
SIAM Journal on Applied Mathematics, 2011, 71 (6), pp.2246-2268. ⟨10.1137/100815517⟩
Article dans une revue hal-00538496v2
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Application of Hybrid Models to Blood Cell Production in the Bone Marrow

Nikolai Bessonov , Fabien Crauste , Stephan Fisher , Polina Kurbatova , Vitaly Volpert
Mathematical Modelling of Natural Phenomena, 2011, 6 (7), pp.2-12. ⟨10.1051/mmnp/20116701⟩
Article dans une revue hal-00649217v1
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Mathematical study of feedback control roles and relevance in stress erythropoiesis

Fabien Crauste , Ivan Demin , Olivier Gandrillon , Vitaly Volpert
Journal of Theoretical Biology, 2010, 263 (3), pp.303. ⟨10.1016/j.jtbi.2009.12.026⟩
Article dans une revue hal-00567288v1
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Stability and Hopf bifurcation for a cell population model with state-dependent delay

Mostafa Adimy , Fabien Crauste , Hassan Hbid , Redouane Qesmi
SIAM Journal on Applied Mathematics, 2010, 70 (5), pp.1611-1633. ⟨10.1137/080742713⟩
Article dans une revue hal-00542655v1

Asymptotic behavior and stability switch for a mature-immature model of cell differentiation

Mostafa Adimy , Fabien Crauste , Catherine Marquet
Nonlinear Analysis: Real World Applications, 2010, 11 (4), pp.2913-2929. ⟨10.1016/j.nonrwa.2009.11.001⟩
Article dans une revue hal-00542644v1

Boundedness and Lyapunov Function for a Nonlinear System of Hematopoietic Stem Cell Dynamics

Mostafa Adimy , Fabien Crauste , Abderrahim El Abdllaoui
Comptes Rendus. Mathématique, 2010, 348 (7-8), pp.373-377. ⟨10.1016/j.crma.2010.02.018⟩
Article dans une revue hal-00542477v1

Mathematical study of feedback control roles and relevance in stress erythropoiesis.

Fabien Crauste , Ivan Demin , Olivier Gandrillon , Vitaly Volpert
Journal of Theoretical Biology, 2010, 263 (3), pp.303-16. ⟨10.1016/j.jtbi.2009.12.026⟩
Article dans une revue hal-00542457v1

A multi-scale model of erythropoiesis

Ivan Demin , Fabien Crauste , Olivier Gandrillon , Vitaly Volpert
Journal of Biological Dynamics, 2010, 4 (1), pp.59-70. ⟨10.1080/17513750902777642⟩
Article dans une revue hal-00542669v1

Mathematical model of hematopoiesis dynamics with growth factor-dependent apoptosis and proliferation regulation

Fabien Crauste , Mostafa Adimy
Mathematical and Computer Modelling, 2009, 49, pp.2128-2137. ⟨10.1016/j.mcm.2008.07.014⟩
Article dans une revue hal-00542665v1
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Delay Model of Hematopoietic Stem Cell Dynamics: Asymptotic Stability and Stability Switch

Fabien Crauste
Mathematical Modelling of Natural Phenomena, 2009, 4 (2), pp.28-47. ⟨10.1051/mmnp/20094202⟩
Article dans une revue hal-00542663v1
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Dynamics of erythroid progenitors and erythroleukemia

Nikolai Bessonov , Fabien Crauste , Ivan Demin , Vitaly Volpert
Mathematical Modelling of Natural Phenomena, 2009, Cancer modelling (Part 2), 4 (3), pp.210-232. ⟨10.1051/mmnp/20094309⟩
Article dans une revue hal-00542660v1

Discrete maturity-structured model of cell differentiation with applications to acute myelogenous leukemia

Mostafa Adimy , Fabien Crauste , Abderrahim El Abdllaoui
Journal of Biological Systems, 2008, 16 (3), pp.395-424. ⟨10.1142/S0218339008002599⟩
Article dans une revue hal-00750276v1
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Modélisation de la dynamique de l'hématopoïèse normale et pathologique

Mostafa Adimy , Samuel Bernard , Jean Clairambault , Fabien Crauste , Stéphane Génieys
Hématologie, 2008, 14 (5), pp.339-350. ⟨10.1684/hma.2008.0282⟩
Article dans une revue hal-00750278v1

Numerical integration of a mathematical model of hematopoietic stem cell dynamics

Mostafa Adimy , Oscar Angulo , Fabien Crauste , Juan Carlos Lopez-Marcos
Computers & Mathematics with Applications, 2008, 56, pp.594-606. ⟨10.1016/j.camwa.2008.01.003⟩
Article dans une revue hal-00750283v1

A delay reaction-diffusion model of the dynamics of botulinum in fish.

Fabien Crauste , M Lhassan Hbid , Abdelaziz Kacha
Mathematical Biosciences, 2008, 216 (1), pp.17-29. ⟨10.1016/j.mbs.2008.07.012⟩
Article dans une revue hal-00542466v1

Adding self-renewal in committed erythroid progenitors improves the biological relevance of a mathematical model of erythropoiesis.

Fabien Crauste , Laurent Pujo-Menjouet , Stéphane Génieys , Clément Molina , Olivier Gandrillon
Journal of Theoretical Biology, 2008, 250, pp.322-338. ⟨10.1016/j.jtbi.2007.09.041⟩
Article dans une revue hal-00194422v1
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Modelling and Asymptotic Stability of a Growth Factor-Dependent Stem Cells Dynamics Model with Distributed Delay

Mostafa Adimy , Fabien Crauste
Discrete and Continuous Dynamical Systems - Series B, 2007, 8 (1), pp.19-38. ⟨10.3934/dcdsb.2007.8.19⟩
Article dans une revue hal-00258392v1

Asymptotic Behavior of a Discrete Maturity Structured System of Hematopoietic Stem Cells Dynamics with Several Delays

Mostafa Adimy , Fabien Crauste , Abderrahim El Abdllaoui
Mathematical Modelling of Natural Phenomena, 2006, 1 (2), pp.1-22. ⟨10.1051/mmnp:2008001⟩
Article dans une revue hal-00750285v1
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Modelling hematopoiesis mediated by growth factors with applications to periodic hematological diseases

Mostafa Adimy , Fabien Crauste , Shigui Ruan
Bulletin of Mathematical Biology, 2006, 68 (8), pp.2321-2351. ⟨10.1007/s11538-006-9121-9⟩
Article dans une revue hal-00376087v1
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Periodic Oscillations in Leukopoiesis Models with Two Delays

Mostafa Adimy , Fabien Crauste , Shigui Ruan
Journal of Theoretical Biology, 2006, 242, pp.288-299. ⟨10.1016/j.jtbi.2006.02.020⟩
Article dans une revue hal-00258393v1
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Global Asymptotic Stability and Hopf Bifurcation for a Blood Cell Production Model

Fabien Crauste
Mathematical Biosciences and Engineering, 2006, 3 (2), pp.325-346
Article dans une revue hal-00376070v2
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Stability of limit cycles in a pluripotent stem cell dynamics model

Mostafa Adimy , Fabien Crauste , Andrei Halanay , Mihaela Neamtu , Dumitru Opris
Chaos, Solitons & Fractals, 2006, 27 (4), pp.1091-1107. ⟨10.1016/j.chaos.2005.04.083⟩
Article dans une revue hal-00376002v1
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On the stability of a maturity structured model of cellular proliferation

Mostafa Adimy , Fabien Crauste , Laurent Pujo-Menjouet
Discrete and Continuous Dynamical Systems - Series A, 2005, 12 (3), pp.501-522. ⟨10.3934/dcds.2005.12.501⟩
Article dans une revue hal-00375940v1
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Stability and Hopf bifurcation in a mathematical model of pluripotent stem cell dynamics

Mostafa Adimy , Fabien Crauste , Shigui Ruan
Nonlinear Analysis: Real World Applications, 2005, 6 (4), pp.651-670. ⟨10.1016/j.nonrwa.2004.12.010⟩
Article dans une revue hal-00375966v1
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Existence, positivity and stability for a nonlinear model of cellular proliferation

Mostafa Adimy , Fabien Crauste
Nonlinear Analysis: Real World Applications, 2005, 6 (2), pp.337-366. ⟨10.1016/j.nonrwa.2004.09.001⟩
Article dans une revue hal-00375934v1
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A mathematical study of the hematopoiesis process with applications to chronic myelogenous leukemia

Mostafa Adimy , Fabien Crauste , Shigui Ruan
SIAM Journal on Applied Mathematics, 2005, 65 (4), pp.1328-1352. ⟨10.1137/040604698⟩
Article dans une revue hal-00375977v1
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Global stability of a partial differential equation with distributed delay due to cellular replication

Mostafa Adimy , Fabien Crauste
Nonlinear Analysis: Theory, Methods and Applications, 2003, 54 (8), pp.1469-1491. ⟨10.1016/S0362-546X(03)00197-4⟩
Article dans une revue hal-00375926v1
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Un modèle non-linéaire de prolifération cellulaire : extinction des cellules et invariance

Mostafa Adimy , Fabien Crauste
Comptes Rendus. Mathématique, 2003, 336 (7), pp.559-564. ⟨10.1016/S1631-073X(03)00125-0⟩
Article dans une revue hal-00375916v1
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Equations à Retard et Modèles de Dynamiques de Populations Cellulaires

Fabien Crauste
Mathématiques générales [math.GM]. Université Claude Bernard Lyon 1, 2014
HDR tel-01092352v1