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  • Sarah Trouvilliez, Julien Cicero, Romain Lévêque, Léo Aubert, Cyril Corbet, et al.. Direct interaction of TrkA/CD44v3 is essential for NGF-promoted aggressiveness of breast cancer cells. Journal of experimental & clinical cancer research, BioMed Central, 2022, 41 (1), pp.110. ⟨10.1186/s13046-022-02314-4⟩. ⟨hal-03641786⟩
  • Ophélie da Silva, Nicolas Probst, Christophe Landry, Anne-Sophie Hanak, Pierre Warnault, et al.. A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning. Journal of Medicinal Chemistry, American Chemical Society, 2022, 65 (6), pp.4649-4666. ⟨10.1021/acs.jmedchem.1c01748⟩. ⟨hal-03706969⟩
  • Romain Versele, Emmanuel Sevin, Fabien Gosselet, Laurence Tilloy-Fenart, Pietra Candela. TNF-α and IL-1β Modulate Blood-Brain Barrier Permeability and Decrease Amyloid-β Peptide Efflux in a Human Blood-Brain Barrier Model. International Journal of Molecular Sciences, MDPI, 2022, 23 (18), pp.10235. ⟨10.3390/ijms231810235⟩. ⟨hal-03786823⟩
  • Elisa L.J. Moya, Sonia Lombardo, Elodie Vandenhaute, Marc Schneider, Caroline Mysiorek, et al.. Interaction of surfactant coated PLGA nanoparticles with in vitro human brain-like endothelial cells. International Journal of Pharmaceutics, Elsevier, 2022, 621, pp.121780. ⟨10.1016/j.ijpharm.2022.121780⟩. ⟨hal-03707013⟩
  • Gustavo Henrique Oliveira da Rocha, Rodrigo Azevedo Loiola, Marina de Paula-Silva, Fumitaka Shimizu, Takashi Kanda, et al.. Pioglitazone Attenuates the Effects of Peripheral Inflammation in a Human In Vitro Blood–Brain Barrier Model. International Journal of Molecular Sciences, MDPI, 2022, 23, ⟨10.3390/ijms232112781⟩. ⟨hal-03851672⟩
  • Camille Menaceur, Fabien Gosselet, Laurence Fenart, Julien Saint-Pol. The Blood–Brain Barrier, an Evolving Concept Based on Technological Advances and Cell–Cell Communications. Cells, MDPI, 2022, 11 (1), pp.133. ⟨10.3390/cells11010133⟩. ⟨hal-03706905⟩
  • Sara Wellens, Fabien Gosselet, Maxime Culot. Challenges and opportunities in the use of transcriptomics characterization for human iPSC-derived BBB models. Toxicology in Vitro, Elsevier, In press, ⟨10.1016/j.tiv.2022.105424⟩. ⟨hal-03708257v1⟩
  • Daniel Rand, Orly Ravid, Dana Atrakchi, Hila Israelov, Yael Bresler, et al.. Endothelial Iron Homeostasis Regulates Blood-Brain Barrier Integrity via the HIF2α—Ve-Cadherin Pathway. Pharmaceutics, MDPI, 2021, 13 (3), pp.311. ⟨10.3390/pharmaceutics13030311⟩. ⟨hal-03185677⟩
  • Wei Yan, Lingtian Zhang, Fengping Lv, Marialuisa Moccia, Francesca Carlomagno, et al.. Discovery of pyrazolo-thieno[3,2-d]pyrimidinylamino-phenyl acetamides as type-II pan-tropomyosin receptor kinase (TRK) inhibitors: Design, synthesis, and biological evaluation. European Journal of Medicinal Chemistry, Elsevier, 2021, 216, pp.113265. ⟨10.1016/j.ejmech.2021.113265⟩. ⟨hal-03185627⟩
  • Elisa Moya, Elodie Vandenhaute, Eleonora Rizzi, Marie-Christine Boucau, Johan Hachani, et al.. Miniaturization and Automation of a Human In Vitro Blood–Brain Barrier Model for the High-Throughput Screening of Compounds in the Early Stage of Drug Discovery. Pharmaceutics, MDPI, 2021, 13 (6), pp.892. ⟨10.3390/pharmaceutics13060892⟩. ⟨hal-03472477⟩
  • Camille Tisnerat, Alexandra Dassonville-Klimpt, Fabien Gosselet, Pascal Sonnet. Antimalarial drug discovery: from quinine to the most recent promising clinical drug candidates. Current Medicinal Chemistry, Bentham Science Publishers, 2021, 28, ⟨10.2174/0929867328666210803152419⟩. ⟨hal-03472321⟩
  • Eleonora Rizzi, Clémence Deligne, Lucie Dehouck, Roberta Bilardo, Yasuteru Sano, et al.. A Triple Culture Cell System Modeling the Human Blood-Brain Barrier. Journal of visualized experiments : JoVE, JoVE, 2021, 177, ⟨10.3791/63134⟩. ⟨hal-03706896⟩
  • Marion Clé, Orianne Constant, Jonathan Barthelemy, Caroline Desmetz, Marie France Martin, et al.. Differential neurovirulence of Usutu virus lineages in mice and neuronal cells. Journal of Neuroinflammation, BioMed Central, 2021, 18 (1), ⟨10.1186/s12974-020-02060-4⟩. ⟨hal-03126852⟩
  • Fabien Gosselet, Rodrigo Azevedo Loiola, Anna Roig, Anna Rosell, Maxime Culot. Central nervous system delivery of molecules across the blood-brain barrier. Neurochemistry International, Elsevier, 2021, 144, ⟨10.1016/j.neuint.2020.104952⟩. ⟨hal-03282235⟩
  • Aniela Bittner, Fabien Gosselet, Emmanuel Sevin, Lucie Dehouck, Angélique Ducray, et al.. Time-Dependent Internalization of Polymer-Coated Silica Nanoparticles in Brain Endothelial Cells and Morphological and Functional Effects on the Blood-Brain Barrier. International Journal of Molecular Sciences, MDPI, 2021, 22 (4), pp.1657. ⟨10.3390/ijms22041657⟩. ⟨hal-03185554⟩
  • Marion Clé, Orianne Constant, Jonathan Barthelemy, Caroline Desmetz, Marie France Martin, et al.. Differential neurovirulence of Usutu viruslineages in mice and neuronal cells. Journal of Neuroinflammation, BioMed Central, 2021, 18 (1), pp.59. ⟨10.1186/s12974-021-02109-y⟩. ⟨hal-03678372⟩
  • Vanessa Hoguet, Manuel Lasalle, Mathieu Maingot, Geoffroy Dequirez, Rajaa Boulahjar, et al.. Beyond the Rule of 5: Impact of PEGylation with Various Polymer Sizes on Pharmacokinetic Properties, Structure–Properties Relationships of mPEGylated Small Agonists of TGR5 Receptor. Journal of Medicinal Chemistry, American Chemical Society, 2021, 64 (3), pp.1593-1610. ⟨10.1021/acs.jmedchem.0c01774⟩. ⟨hal-03185533⟩
  • Sara Wellens, Lucie Dehouck, Vidya Chandrasekaran, Pranika Singh, Rodrigo Azevedo Loiola, et al.. Evaluation of a human iPSC-derived BBB model for repeated dose toxicity testing with cyclosporine A as model compound. Toxicology in Vitro, Elsevier, 2021, 73, pp.105112. ⟨10.1016/j.tiv.2021.105112⟩. ⟨hal-03185595⟩
  • Shahar Shelly, Sigal Liraz Zaltsman, Ofir Ben-Gal, Avraham Dayan, Ithamar Ganmore, et al.. Potential neurotoxicity of titanium implants: Prospective, in-vivo and in-vitro study. Biomaterials, Elsevier, 2021, 276, pp.121039. ⟨10.1016/j.biomaterials.2021.121039⟩. ⟨hal-03472462⟩
  • Ana R Santa-Maria, Fruzsina R Walter, Ricardo Figueiredo, András Kincses, Judith Vigh, et al.. Flow induces barrier and glycocalyx-related genes and negative surface charge in a lab-on-a-chip human blood-brain barrier model. Journal of Cerebral Blood Flow and Metabolism, Nature Publishing Group, 2021, 41 (9), pp.2201-2215. ⟨10.1177/0271678X21992638⟩. ⟨hal-03185580⟩
  • Shiraz Dib, Jens Pahnke, Fabien Gosselet. Role of ABCA7 in Human Health and in Alzheimer’s Disease. International Journal of Molecular Sciences, MDPI, 2021, 22 (9), pp.4603. ⟨10.3390/ijms22094603⟩. ⟨hal-03472487⟩
  • Orianne Constant, Jonathan Barthelemy, Karine Bolloré, Edouard Tuaillon, Fabien Gosselet, et al.. SARS-CoV-2 Poorly Replicates in Cells of the Human Blood-Brain Barrier Without Associated Deleterious Effects. Frontiers in Immunology, Frontiers, 2021, 12, pp.697329. ⟨10.3389/fimmu.2021.697329⟩. ⟨hal-03455730⟩
  • Elisabet Sjöström, Maxime Culot, Lisa Leickt, Mikael Åstrand, Erik Nordling, et al.. Transport study of interleukin-1 inhibitors using a human in vitro model of the blood-brain barrier. Brain, Behavior & Immunity - Health, Elsevier, 2021, 16, pp.100307. ⟨10.1016/j.bbih.2021.100307⟩. ⟨hal-03472272⟩
  • Rodrigo Azevedo Loiola, Miguel García-Gabilondo, Alba Grayston, Paulina Bugno, Agnieszka Kowalska, et al.. Secretome of endothelial progenitor cells from stroke patients promotes endothelial barrier tightness and protects against hypoxia-induced vascular leakage. Current Stem Cell Research & Therapy, Bentham Science Publishers Ltd, 2021, 12 (1), ⟨10.1186/s13287-021-02608-y⟩. ⟨hal-03472260⟩
  • Romain Versele, Mariangela Corsi, Andrea Fuso, Emmanuel Sevin, Rita Businaro, et al.. Ketone Bodies Promote Amyloid-β1–40 Clearance in a Human in Vitro Blood–Brain Barrier Model. International Journal of Molecular Sciences, 2020, 21 (3), pp.934. ⟨10.3390/ijms21030934⟩. ⟨hal-02538226⟩
  • Florian Nolay, Emmanuel Sevin, Mathieu Létévé, Abed Bil, Fabien Gosselet, et al.. First step to the improvement of the blood brain barrier passage of atazanavir encapsulated in sustainable bioorganic vesicles. International Journal of Pharmaceutics, Elsevier, 2020, 587, pp.119604. ⟨10.1016/j.ijpharm.2020.119604⟩. ⟨hal-02980826⟩
  • Marion Clé, Caroline Desmetz, Jonathan Barthelemy, Marie-France Martin, Orianne Constant, et al.. Zika Virus Infection Promotes Local Inflammation, Cell Adhesion Molecule Upregulation, and Leukocyte Recruitment at the Blood-Brain Barrier. mBio, American Society for Microbiology, 2020, 11 (4), ⟨10.1128/mBio.01183-20⟩. ⟨hal-02914994⟩
  • Julien Saint-Pol, Fabien Gosselet, Sophie Duban-Deweer, Gwënaël Pottiez, Yannis Karamanos. Targeting and Crossing the Blood-Brain Barrier with Extracellular Vesicles. Cells, MDPI, 2020, 9 (4), pp.851. ⟨10.3390/cells9040851⟩. ⟨hal-02538286⟩
  • André-Guilhem Calas, Anne-Sophie Hanak, Nina Jaffré, Aurélie Nervo, José Dias, et al.. Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime. Biomolecules, MDPI, 2020, 10 (6), pp.858. ⟨10.3390/biom10060858⟩. ⟨hal-03127255⟩
  • Hideaki Nishihara, Benjamin Gastfriend, Sasha Soldati, Sylvain Perriot, Amandine Mathias, et al.. Advancing human induced pluripotent stem cell‐derived blood‐brain barrier models for studying immune cell interactions. FASEB Journal, Federation of American Society of Experimental Biology, 2020, 34 (12), pp.16693-16715. ⟨10.1096/fj.202001507RR⟩. ⟨hal-03126912⟩
  • Marion Clé, Jonathan Barthelemy, Caroline Desmetz, Vincent Foulongne, Lina Lapeyre, et al.. Study of Usutu virus neuropathogenicity in mice and human cellular models. PLoS Neglected Tropical Diseases, Public Library of Science, 2020, 14 (4), pp.e0008223. ⟨10.1371/journal.pntd.0008223⟩. ⟨hal-02886700⟩
  • Ilona Gróf, Alexandra Bocsik, András Harazin, Ana Raquel Santa-Maria, Gaszton Vizsnyiczai, et al.. The Effect of Sodium Bicarbonate, a Beneficial Adjuvant Molecule in Cystic Fibrosis, on Bronchial Epithelial Cells Expressing a Wild-Type or Mutant CFTR Channel. International Journal of Molecular Sciences, MDPI, 2020, 21 (11), pp.4024. ⟨10.3390/ijms21114024⟩. ⟨hal-03127314⟩
  • Estefania Oliva, David Mathiron, Sébastien Rigaud, Eric Monflier, Emmanuel Sevin, et al.. New Lipidyl-Cyclodextrins Obtained by Ring Opening of Methyl Oleate Epoxide Using Ball Milling. Biomolecules, MDPI, 2020, Perspectives of Cyclodextrins, 10 (2), pp.1-18/339. ⟨hal-02486048⟩
  • Hideaki Nishihara, Sasha Soldati, Adrien Mossu, Maria Rosito, Henriette Rudolph, et al.. Human CD4+ T cell subsets differ in their abilities to cross endothelial and epithelial brain barriers in vitro. Fluids and Barriers of the CNS, 2020, 17, pp.3. ⟨10.1186/s12987-019-0165-2⟩. ⟨hal-02505269⟩
  • Estefania Oliva, David Mathiron, Sébastien Rigaud, Eric Monflier, Emmanuel Sevin, et al.. New Lipidyl-Cyclodextrins Obtained by Ring Opening of Methyl Oleate Epoxide Using Ball Milling. Biomolecules, MDPI, 2020, 10 (2), pp.339. ⟨10.3390/biom10020339⟩. ⟨hal-03832638⟩
  • Anupriya Mehra, Sylvaine Guérit, Richard Macrez, Fabien Gosselet, Emmanuel Sevin, et al.. Nonionotropic Action of Endothelial NMDA Receptors on Blood–Brain Barrier Permeability via Rho/ROCK-Mediated Phosphorylation of Myosin. Journal of Neuroscience, Society for Neuroscience, 2020, 40 (8), pp.1778-1787. ⟨10.1523/JNEUROSCI.0969-19.2019⟩. ⟨hal-02535778⟩
  • Ashim Paul, Adi Huber, Daniel Rand, Fabien Gosselet, Itzik Cooper, et al.. Naphthoquinone–Dopamine Hybrids Inhibit α‐Synuclein Aggregation, Disrupt Preformed Fibrils, and Attenuate Aggregate‐Induced Toxicity. Chemistry - A European Journal, Wiley-VCH Verlag, 2020, 26 (69), pp.16486-16496. ⟨10.1002/chem.202003374⟩. ⟨hal-03126960⟩
  • Anupriya Mehra, Lucie Dehouck, Elodie Vandenhaute, Marc Fatar, Laurence Fenart, et al.. A High Output Method to Isolate Cerebral Pericytes from Mouse. Journal of visualized experiments : JoVE, JoVE, 2020, 155, ⟨10.3791/60588⟩. ⟨hal-02535814⟩
  • Yajie Zhang, Miguel García-Gabilondo, Alba Grayston, Irene Feiner, Irene Anton-Sales, et al.. PLGA protein nanocarriers with tailor-made fluorescence/MRI/PET imaging modalities. Nanoscale, Royal Society of Chemistry, 2020, 12 (8), pp.4988-5002. ⟨10.1039/c9nr10620k⟩. ⟨hal-02538272⟩
  • Erika Di Biase, Giulia Lunghi, Margherita Maggioni, Maria Fazzari, Diego Yuri Pomè, et al.. GM1 Oligosaccharide Crosses the Human Blood–Brain Barrier In Vitro by a Paracellular Route. International Journal of Molecular Sciences, MDPI, 2020, 21 (8), pp.2858. ⟨10.3390/ijms21082858⟩. ⟨hal-03127393⟩
  • Hila Israelov, Orly Ravid, Dana Atrakchi, Daniel Rand, Shirin Elhaik, et al.. Caspase-1 has a critical role in blood-brain barrier injury and its inhibition contributes to multifaceted repair. Journal of Neuroinflammation, BioMed Central, 2020, 17 (1), ⟨10.1186/s12974-020-01927-w⟩. ⟨hal-03126925⟩
  • Liadys Mora Lagares, Nikola Minovski, Ana Yisel Caballero Alfonso, Emilio Benfenati, Sara Wellens, et al.. Homology Modeling of the Human P-glycoprotein (ABCB1) and Insights into Ligand Binding through Molecular Docking Studies. International Journal of Molecular Sciences, MDPI, 2020, 21 (11), pp.4058. ⟨10.3390/ijms21114058⟩. ⟨hal-03127238⟩
  • Marjolein Heymans, Ricardo Figueiredo, Lucie Dehouck, David Francisco, Yasuteru Sano, et al.. Contribution of brain pericytes in blood–brain barrier formation and maintenance: a transcriptomic study of cocultured human endothelial cells derived from hematopoietic stem cells. Fluids and Barriers of the CNS, BioMed Central, 2020, 17 (1), ⟨10.1186/s12987-020-00208-1⟩. ⟨hal-03127036⟩
  • Carolin Curtaz, Constanze Schmitt, Saskia-Laureen Herbert, Jonas Feldheim, Nicolas Schlegel, et al.. Serum-derived factors of breast cancer patients with brain metastases alter permeability of a human blood–brain barrier model. Fluids and Barriers of the CNS, BioMed Central, 2020, 17, pp.31. ⟨10.1186/s12987-020-00192-6⟩. ⟨hal-03127441⟩
  • Jagadeesh Yerri, José Dias, Mallikajurna Reddy Nimmakayala, Franck Razafindrainibe, Charlotte Courageux, et al.. Chemoselective Hydrogenation of 6‐Alkynyl‐3‐fluoro‐2‐pyridinaldoximes: Access to First‐in‐Class 6‐Alkyl‐3‐Fluoro‐2‐pyridinaldoxime Scaffolds as New Reactivators of Sarin‐Inhibited Human Acetylcholinesterase with Increased Blood–Brain Barrier Permeability. Chemistry - A European Journal, Wiley-VCH Verlag, 2020, 26 (65), pp.15035-15044. ⟨10.1002/chem.202002012⟩. ⟨hal-03127205⟩
  • Julien Saint-Pol, Fabien Gosselet. Oxysterols and the NeuroVascular Unit (NVU): A far true love with bright and dark sides. Journal of Steroid Biochemistry and Molecular Biology, Elsevier, 2019, 191 (105368), ⟨10.1016/j.jsbmb.2019.04.017⟩. ⟨hal-02505516⟩
  • Guru Krishnakumar Viswanathan, Dana Shwartz, Yelena Losev, Elad Arad, Chen Shemesh, et al.. Purpurin modulates Tau-derived VQIVYK fibrillization and ameliorates Alzheimer’s disease-like symptoms in animal model. Cellular and Molecular Life Sciences, Springer Verlag, 2019, ⟨10.1007/s00018-019-03312-0⟩. ⟨hal-02505419⟩
  • Shirley Sharabi, Yael Bresler, Orly Ravid, Chen Shemesh, Dana Atrakchi, et al.. Transient blood–brain barrier disruption is induced by low pulsed electrical fields in vitro: an analysis of permeability and trans-endothelial electric resistivity. Drug Delivery, Taylor & Francis, 2019, 26 (1), pp.459-469. ⟨10.1080/10717544.2019.1571123⟩. ⟨hal-02505306⟩
  • Britta Engelhardt, Isabella Wimmer, Silvia Tietz, Hideaki Nishihara, Urban Deutsch, et al.. PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation. Frontiers in Immunology, Frontiers, 2019, 10, pp.711. ⟨10.3389/fimmu.2019.00711⟩. ⟨hal-02505535⟩
  • Emmanuel Sevin, Lucie Dehouck, Romain Versele, Maxime Culot, Fabien Gosselet. A Miniaturized Pump Out Method for Characterizing Molecule Interaction with ABC Transporters. International Journal of Molecular Sciences, MDPI, 2019, 20, ⟨10.3390/ijms20225529⟩. ⟨hal-03282234⟩
  • Yordenca Lamartinière, Marie-Christine Boucau, Lucie Dehouck, Markus Krohn, Jens Pahnke, et al.. ABCA7 Downregulation Modifies Cellular Cholesterol Homeostasis and Decreases Amyloid-β Peptide Efflux in an in vitro Model of the Blood-Brain Barrier. Journal of Alzheimer's Disease, IOS Press, 2018, 64 (4), pp.1195-1211. ⟨10.3233/JAD-170883⟩. ⟨hal-02506137⟩
  • Julien Saint-Pol, Fabien Gosselet. Petits mais costauds: Les exosomes neuronaux contrôlent l’intégrité vasculaire cérébrale. médecine/sciences, EDP Sciences, 2018, 34 (4), pp.303-306. ⟨10.1051/medsci/20183404008⟩. ⟨hal-02504238⟩
  • Huilong Luo, Matthieu Gauthier, Xi Tan, Christophe Landry, Joël Poupon, et al.. Sodium Transporters Are Involved in Lithium Influx in Brain Endothelial Cells. Molecular Pharmaceutics, American Chemical Society, 2018, 15 (7), pp.2528-2538. ⟨10.1021/acs.molpharmaceut.8b00018⟩. ⟨hal-02506165⟩
  • Orly Ravid, Shirin Elhaik Goldman, David Macheto, Yael Bresler, Raquel Ines de Oliveira, et al.. Blood-Brain Barrier Cellular Responses Toward Organophosphates: Natural Compensatory Processes and Exogenous Interventions to Rescue Barrier Properties. Frontiers in Cellular Neuroscience, Frontiers, 2018, 12 (359), ⟨10.3389/fncel.2018.00359⟩. ⟨hal-02505618⟩
  • Dorothee Domenger, Benoît Cudennec, Mostafa Kouach, Véronique Touche, Christophe Landry, et al.. Food-Derived Hemorphins Cross Intestinal and Blood–Brain Barriers In Vitro. Frontiers in Endocrinology, Frontiers, 2018, 9, pp.159. ⟨10.3389/fendo.2018.00159⟩. ⟨hal-02506264⟩
  • M.J. Ramalho, Emmanuel Sevin, F. Gosselet, J. Lima, M.A.N. Coelho, et al.. Receptor-mediated PLGA nanoparticles for glioblastoma multiforme treatment. International Journal of Pharmaceutics, Elsevier, 2018, 545 (1-2), pp.84-92. ⟨10.1016/j.ijpharm.2018.04.062⟩. ⟨hal-02506188⟩
  • Adrien Mossu, Maria Rosito, Tejas Khire, Hung Li Chung, Hideaki Nishihara, et al.. A silicon nanomembrane platform for the visualization of immune cell trafficking across the human blood–brain barrier under flow. Journal of Cerebral Blood Flow and Metabolism, Nature Publishing Group, 2018, 39 (3), pp.395-410. ⟨10.1177/0271678X18820584⟩. ⟨hal-02505603⟩
  • Geoffrey Canet, Chloé Dias, Audrey Gabelle, Yannick Simonin, Fabien Gosselet, et al.. HIV Neuroinfection and Alzheimer’s Disease: Similarities and Potential Links?. Frontiers in Cellular Neuroscience, Frontiers, 2018, 12, ⟨10.3389/fncel.2018.00307⟩. ⟨hal-02130334⟩
  • Marjolein Heymans, Emmanuel Sevin, Fabien Gosselet, Stefan Lundquist, Maxime Culot. Mimicking brain tissue binding in an in vitro model of the blood-brain barrier illustrates differences between in vitro and in vivo methods for assessing the rate of brain penetration. European Journal of Pharmaceutics and Biopharmaceutics, Elsevier, 2018, 127, pp.453-461. ⟨10.1016/j.ejpb.2018.03.007⟩. ⟨hal-02506299⟩
  • Manuel Lasalle, Vanessa Hoguet, Nathalie Hennuyer, Florence Leroux, Catherine Piveteau, et al.. Topical Intestinal Aminoimidazole Agonists of G-Protein-Coupled Bile Acid Receptor 1 Promote Glucagon Like Peptide-1 Secretion and Improve Glucose Tolerance. Journal of Medicinal Chemistry, American Chemical Society, 2017, 60 (10), pp.4185-4211. ⟨10.1021/acs.jmedchem.6b01873⟩. ⟨inserm-02115415⟩
  • Fabien Gosselet. Modélisation in vitro de la barrière hémato-encéphalique. médecine/sciences, EDP Sciences, 2017, 33 (4), pp.423-431. ⟨10.1051/medsci/20173304013⟩. ⟨hal-00543630⟩
  • Kati-Sisko Vellonen, Jouni Ihalainen, Marie-Christine Boucau, Fabien Gosselet, Théo Picardat, et al.. Disease-Induced Alterations in Brain Drug Transporters in Animal Models of Alzheimer’s Disease. Pharmaceutical Research, American Association of Pharmaceutical Scientists, 2017, 34 (12), pp.2652-2662. ⟨10.1007/s11095-017-2263-7⟩. ⟨hal-02506588⟩
  • Joana Loureiro, Stephanie Andrade, Ana Duarte, Ana Neves, Joana Queiroz, et al.. Resveratrol and Grape Extract-loaded Solid Lipid Nanoparticles for the Treatment of Alzheimer’s Disease. Molecules, MDPI, 2017, 22 (2), pp.277. ⟨10.3390/molecules22020277⟩. ⟨hal-02506654⟩
  • Ruth Lyck, Marc-André Lécuyer, Michael Abadier, Christof Wyss, Christoph Matti, et al.. ALCAM (CD166) is involved in extravasation of monocytes rather than T cells across the blood–brain barrier. Journal of Cerebral Blood Flow and Metabolism, Nature Publishing Group, 2017, 37 (8), pp.2894-2909. ⟨10.1177/0271678X16678639⟩. ⟨hal-02506628⟩
  • Elodie Vandenhaute, Aurore Drolez, Emmanuel Sevin, Fabien Gosselet, Caroline Mysiorek, et al.. Adapting co-culture in vitro models of the blood–brain barrier for use in cancer research: maintaining an appropriate endothelial monolayer for the assessment of transendothelial migration. Laboratory Investigation, Nature Publishing Group, 2016, 96 (5), pp.588-598. ⟨10.1038/labinvest.2016.35⟩. ⟨hal-02510335⟩
  • Daniela Elisabeth Eigenmann, Carmen Dürig, Evelyn Andrea Jähne, Martin Smieško, Maxime Culot, et al.. In vitro blood–brain barrier permeability predictions for GABAA receptor modulating piperine analogs. European Journal of Pharmaceutics and Biopharmaceutics, Elsevier, 2016, 103, pp.118-126. ⟨10.1016/j.ejpb.2016.03.029⟩. ⟨hal-02510088⟩
  • M. Hachem, A. Geloen, A. L. Van, B. Foumaux, L. Fenart, et al.. Efficient Docosahexaenoic Acid Uptake by the Brain from a Structured Phospholipid. Molecular Neurobiology, Humana Press, 2016, 53 (5), pp.3205-3215. ⟨10.1007/s12035-015-9228-9⟩. ⟨hal-01850313⟩
  • Cristina Merino-Zamorano, Sofía Fernández-de Retana, Alex Montañola, Aina Batlle, Julien Saint-Pol, et al.. Modulation of Amyloid-β1–40 Transport by ApoA1 and ApoJ Across an in vitro Model of the Blood-Brain Barrier. Journal of Alzheimer's Disease, IOS Press, 2016, 53 (2), pp.677-691. ⟨10.3233/JAD-150976⟩. ⟨hal-02506917⟩
  • Evelyn Jähne, Daniela Eigenmann, Chethan Sampath, Veronika Butterweck, Maxime Culot, et al.. Pharmacokinetics and In Vitro Blood-Brain Barrier Screening of the Plant-Derived Alkaloid Tryptanthrin. Planta Medica, Georg Thieme Verlag, 2016, 82 (11/12), pp.1021-1029. ⟨10.1055/s-0042-105295⟩. ⟨hal-02506889⟩
  • Caroline Coisne, Sébastien Tilloy, Eric Monflier, Daniel Wils, Laurence Fenart, et al.. Cyclodextrins as Emerging Therapeutic Tools in the Treatment of Cholesterol-Associated Vascular and Neurodegenerative Diseases. Molecules, MDPI, 2016, 21 (12), pp.1748. ⟨10.3390/molecules21121748⟩. ⟨hal-01681349⟩
  • Luise Schultz, Marie-Gabrielle Zurich, Maxime Culot, Anaelle da Costa, Christophe Landry, et al.. Evaluation of drug-induced neurotoxicity based on metabolomics, proteomics and electrical activity measurements in complementary CNS in vitro models. Toxicology in Vitro, Elsevier, 2015, 30 (1), pp.138-165. ⟨10.1016/j.tiv.2015.05.016⟩. ⟨hal-02513335⟩
  • Aurore Drolez, Elodie Vandenhaute, Sylvain Julien, Fabien Gosselet, Joy Burchell, et al.. Selection of a Relevant In Vitro Blood-Brain Barrier Model to Investigate Pro-Metastatic Features of Human Breast Cancer Cell Lines.. PLoS ONE, Public Library of Science, 2015, 11 (3), pp.e0151155. ⟨10.1371/journal.pone.0151155⟩. ⟨hal-01286618⟩
  • Mélanie Kuntz, Pietra Candela, Julien Saint-Pol, Yordenca Lamartinière, Marie-Christine Boucau, et al.. Bexarotene Promotes Cholesterol Efflux and Restricts Apical-to-Basolateral Transport of Amyloid-β Peptides in an In Vitro Model of the Human Blood-Brain Barrier. Journal of Alzheimer's Disease, IOS Press, 2015, 48 (3), pp.849-862. ⟨10.3233/JAD-150469⟩. ⟨hal-02513306⟩
  • Pietra Candela, Julien Saint-Pol, Mélanie Kuntz, Marie-Christine Boucau, Yordenca Lamartinière, et al.. In vitro discrimination of the role of LRP1 at the BBB cellular level: Focus on brain capillary endothelial cells and brain pericytes. Brain Research, Elsevier, 2015, 1594, pp.15-26. ⟨10.1016/j.brainres.2014.10.047⟩. ⟨hal-02513373⟩
  • Aurore Drolez, Elodie Vandenhaute, Clément Philippe Delannoy, Justine Hélène Dewald, Fabien Gosselet, et al.. ST6GALNAC5 Expression Decreases the Interactions between Breast Cancer Cells and the Human Blood-Brain Barrier.. International Journal of Molecular Sciences, MDPI, 2015, 17 (8), pp.1309. ⟨10.3390/ijms17081309⟩. ⟨hal-01358166⟩
  • Fabien Gosselet, Julien Saint-Pol, Laurence Fenart. Effects of oxysterols on the blood–brain barrier: Implications for Alzheimer’s disease. Biochemical and Biophysical Research Communications, Elsevier, 2014, 446 (3), pp.687-691. ⟨10.1016/j.bbrc.2013.11.059⟩. ⟨hal-02515251⟩
  • Yannis Karamanos, Fabien Gosselet, Marie-Pierre Dehouck, Roméo Cecchelli. Blood–Brain Barrier Proteomics: Towards the Understanding of Neurodegenerative Diseases. Archives of Medical Research, Elsevier, 2014, 45 (8), pp.730-737. ⟨10.1016/j.arcmed.2014.11.008⟩. ⟨hal-02515225⟩
  • Julien Saint-Pol, Pietra Candela, Marie-Christine Boucau, Laurence Fenart, Fabien Gosselet. Oxysterols decrease apical-to-basolateral transport of Aß peptides via an ABCB1-mediated process in an in vitro Blood-brain barrier model constituted of bovine brain capillary endothelial cells. Brain Research, Elsevier, 2013, 1517, pp.1-15. ⟨10.1016/j.brainres.2013.04.008⟩. ⟨hal-02515669⟩
  • Julien Saint-Pol, Pietra Candela, Laurence Fenart, Fabien Gosselet. The LXR/RXR Approaches in Alzheimer’s Disease: Is the Blood-Bra in Barrier the Forgotten Partner?. Journal of Alzheimer’s Disease & Parkinsonism, OMICS International, 2013, 03 (04), ⟨10.4172/2161-0460.1000e131⟩. ⟨hal-02515301⟩
  • Dler Faieeq Darweesh Mahmood, Amna Abderrazak, Dominique Couchie, Oleg Lunov, Vimala Diderot, et al.. Truncated thioredoxin (Trx-80) promotes pro-inflammatory macrophages of the M1 phenotype and enhances atherosclerosis. Journal of Cellular Physiology, Wiley, 2013, 228 (7), pp.1577-1583. ⟨10.1002/jcp.24319⟩. ⟨hal-01544063⟩
  • Elodie Vandenhaute, Maxime Culot, Fabien Gosselet, Lucie Dehouck, Catherine Godfraind, et al.. Brain pericytes from stress-susceptible pigs increase blood-brain barrier permeability in vitro.. Fluids and Barriers of the CNS, BioMed Central, 2012, 9 (1), pp.11. ⟨10.1186/2045-8118-9-11⟩. ⟨inserm-00714318⟩
  • Fabien Gosselet, Pietra Candela, Emmanuel Sevin, Vincent Berezowski, Roméo Cecchelli, et al.. Transcriptional profiles of receptors and transporters involved in brain cholesterol homeostasis at the blood-brain barrier: Use of an in vitro model. Brain Research, Elsevier, 2009, 1249, p. 34-42. ⟨hal-00543674⟩
  • Pietra Candela, Fabien Gosselet, Florence Miller, Valérie Buée-Scherrer, Gérard Torpier, et al.. Physiological pathway for low density lipoproteins across the blood-brain barrier: transcytosis through brain capillary endothelial cells in vitro. Endothelium, Taylor & Francis, 2008, p. 254-264. ⟨hal-00543686⟩

Conference papers3 documents

  • Julien Cicero, Sarah Trouvilliez, Martine Palma, Gaetan Ternier, Laurine Decoster, et al.. Neurotrophins promotes brain metastasis of triple negative breast cancer through Src kinase family activation. 1st ONCOLille days 2022, Nov 2022, Lille, France. ⟨hal-03853963⟩
  • E. Oliva, D. Mathiron, V. Bonnet, S. Pillard, A. Cocq, et al.. «Nano-réacteurs à base de cyclodextrines amphiphiles pour la catalyse et la vectorisation». 5ème Séminaire de recherche PIVERT, 2017, Bordeaux, France. ⟨hal-01726466⟩
  • E. Oliva, D. Mathiron, V. Bonnet, S. Pilard, A. Cocq, et al.. «Nano-réacteurs à base de cyclodextrines amphiphiles pour la catalyse et la vectorisation». 17èmes Journées Cyclodextrines, 2016, Nancy, France. ⟨hal-01726583⟩