Number of documents

16

Mr. Eyad AL MOUAZEN, PharmD., PhD.


Sep 2014 – Present  Associated Professor
University Lyon 1
Teaching at Faculty of Pharmacy ISPB, Pharmaceutical and Cosmetic Technology Department 
Research at LAGEP UMR CNRS 5007 – Pharmaceutical Engineering Team
Design and development of innovative dosage forms for therapeutic applications: working on the elaboration of pharmaceutical formulations, the development of required analytical methods and the needed biological evaluations.
Main projects:
- Development of antigen nanoparticles as a vaccine for veterinary applications.
- Investigation of the therapeutic effects of nanoencapsulated vitamin D3.
- Development of the polymeric nanoparticles for targeting immunity
- Use of nano-encapsulated haptens to improve the performance of skin sensitization non-animal Innovative Drug Delivery Strategies
 
2012 – 2014  Temporary Assistant Professor 
Faculty of Pharmacy ISPB, University Lyon 1, France
Research: oral vaccine development for veterinary application
 
2009 – 2013  PhD student in Pharmaceutical Technology
LAGEP UMR CNRS 5007 and INSERM U1028, University Lyon1, France
Thesis title: Development of polymeric nanoparticles for targeting and modulating macrophage functions.
-Retinoic acid and vitamin D3 encapsulation by nanoprecipitation 
-Evaluation of nanoparticle uptake by macrophages in vitro and in vivo
-Assessment of therapeutical potential of developed nanoparticles 
 
Feb – July 2009  MSc Research internship 
LAGEP UMR CNRS 5007 and INSERM U851, University Lyon1, France
Project title: Use of nano-encapsulated haptens to improve the performance of skin sensitization non-animal test.
-Elaboration of hapten loaded polymeric nanoparticle.
-Test of nanoparticles on dendritic cells – T-cells co-culture.
 
Mar – Sep 2008  Formulation Engineer 
Laboratory of skin care development, L’Oreal-Paris, Chevilly-Larue, France
Project title: New formulation development for cleansing application.
-Formulation and stability study of low viscosity emulsions.
 
Jan – Juin 2007  R&D Engineer
Expanscience Laboratories, Damascus, Syria
-Performed new control methods
-Validation of quality control protocols.
 


Journal articles6 documents

  • Sabrina Nicolas, Marie-Alexandrine Bolzinger, Lars Petter Jordheim, Yves Chevalier, Hatem Fessi, et al.. Polymeric nanocapsules as drug carriers for sustained anticancer activity of calcitriol in breast cancer cells. International Journal of Pharmaceutics, Elsevier, 2018, 550 (1-2), pp.170-179. ⟨10.1016/j.ijpharm.2018.08.022⟩. ⟨hal-02073912⟩
  • Mi Yeon Lee, Sandrine Bourgeois, Eyad Almouazen, Jocelyne Pelletier, Francois Renaud, et al.. Microencapsulation of rifampicin for the prevention of endophthalmitis: In vitro release studies and antibacterial assessment. International Journal of Pharmaceutics, Elsevier, 2016, 505 (1-2), pp.262-270. ⟨10.1016/j.ijpharm.2016.03.026⟩. ⟨hal-01814080⟩
  • J. Steelandt, D. Salmon, E. Gilbert, E. Almouazen, F.N. Renaud, et al.. Antimicrobial nanocapsules: from new solvent-free process to in vitro efficiency. International Journal of Nanomedicine, Dove Medical Press, 2014, 9, pp.4467-4474. ⟨10.2147/IJN.S64746⟩. ⟨hal-01808035⟩
  • Damien Salmon, Julie Steelandt, Elodie Gilbert, Eyad Almouazen, Marek Haftek, et al.. Antimicrobial nanocapsules: from new solvent-free process to in vitro efficiency. International Journal of Nanomedicine, Dove Medical Press, In press, pp.4467. ⟨hal-01958387⟩
  • Eyad Almouazen, Sandrine Bourgeois, Lars Petter Jordheim, Hatem Fessi, Stéphanie Briançon. Nano-encapsulation of Vitamin D3 Active Metabolites for Application in Chemotherapy: Formulation Study and in Vitro Evaluation. Pharmaceutical Research, American Association of Pharmaceutical Scientists, 2013, 30 (4), pp.1137 - 1146. ⟨10.1007/s11095-012-0949-4⟩. ⟨hal-01895860⟩
  • Eyad Almouazen, Sandrine Bourgeois, Ali Boussaïd, Pascale Valot, Celine Malleval, et al.. Development of a nanoparticle-based system for the delivery of retinoic acid into macrophages. International Journal of Pharmaceutics, Elsevier, 2012, 430 (1-2), pp.207-215. ⟨10.1016/j.ijpharm.2012.03.025⟩. ⟨hal-01958051⟩

Conference papers9 documents

  • U. Benavides, E. Almouazen, S. Bourgeois, S. Azzouz, S. Briançon, et al.. Development of nanoparticle delivery system for oral vaccination of dogs. Paravac Meeting, 2014, Cordoba, Spain. ⟨hal-01958034⟩
  • E. Almouazen, S. Bourgeois, L.P. Jordheim, H. Fessi, S. Briancon. Nanoparticles and macrophages enhance anticancer activity of vitamin D3 metabolites. 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2014, Lisbone, Portugal. ⟨hal-02013719⟩
  • Eyad Almouazen, Sandrine Bourgeois, Hatem Fessi, Stéphanie Briançon. Développement de nanoparticules polymères pour le ciblage et la modulation des macrophages. JOURNÉE LYONNAISE AGENTS D’IMAGERIE " Nanoparticules multimodales pour le diagnostic et la thérapie, 2013, Lyon, France. ⟨hal-01958037⟩
  • E. Almouazen, S. Bourgeois, J. Honnorat, S. Briançon. Development of 25-hydroxyvitamin D3 nanoparticles for application in chemotherapy: formulation study. 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2012, Istanbul, Turkey. ⟨hal-01958046⟩
  • E. Almouazen, S. Bourgeois, H. Fessi, S. Briançon. Development of polymeric nanoparticles for targeting and modulating macrophage functions. 17ème Journée scientifique de l’EDISS, 2012, Lyon, France. ⟨hal-01958047⟩
  • E. Almouazen, S. Bourgeois, A. Boussaid, H. Fessi, S. Nataf, et al.. Development of a nanoparticle-based system for the delivery of retinoic acid into macrophages. 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2012, Istanbul, Turkey. ⟨hal-01958045⟩
  • E. Almouazen, S. Bourgeois, A. Boussaid, S. Briançon, S. Nataf, et al.. Development of polymeric nanoparticles for targeting and modulating macrophage functions. 16ème Journée scientifique de l’EDISS, 2011, Lyon, France. ⟨hal-01958057⟩
  • Eyad Almouazen, S. Bourgeois, Ali Boussaïd, Pascale Valot, S. Briançon, et al.. Development of polymeric nanoparticles for modulating macrophage functions. 2nd Conference Innovation in Drug Delivery:From preformulation to development through innovative evaluation process, 2010, Aix en Provence, France. ⟨hal-01958063⟩
  • Eyad Almouazen, S. Bourgeois, Ali Boussaïd, Pascale Valot, S. Briançon, et al.. Development of polymeric nanoparticles for modulating macrophage functions: an original strategy of cellular therapy for autoimmune diseases. 7th world meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2010, Unknown, Malta. ⟨hal-01958066⟩

Theses1 document

  • Eyad Almouazen. Développement de nanoparticules polymères pour le ciblage des macrophages et la modulation des leurs fonctions physiologiques. Médecine humaine et pathologie. Université Claude Bernard - Lyon I, 2013. Français. ⟨NNT : 2013LYO10121⟩. ⟨tel-00945306⟩