Eva Jakab Toth
271
Documents
Identifiants chercheurs
- eva-jakab-toth
- ResearcherId : F-5806-2011
- 0000-0002-3200-6752
- IdRef : 149824726
- ResearcherId : http://www.researcherid.com/rid/F-5806-2011
Présentation
JAKAB TÓTH Éva
==============
Directrice de recherche 1ère classe CNRS
Adresse professionnnelle : Centre de Biophysique Moléculaire, CNRS, Rue Charles Sadron, 45071 Orléans, Cedex 2, France
Phone: +33 2 38 25 55 89
E-mail : eva.jakabtoth@cnrs-orleans.fr
http://cbm.cnrs-orleans.fr/
FORMATION - TITRES SCIENTIFIQUES
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1990 Diplôme universitaire en chimie "Summa cum laude" (Université de Debrecen, Hongrie)
1994 Doctorat en chimie de l'Université de Debrecen, Hongrie (avec félicitations du jury ; summa cum laude)
2004 Habilitation auprès de l'Académie des Sciences de Hongrie
2007 Qualification "Professeurs des Universités" - Section 32
EXPÉRIENCES PROFESSIONNELLES
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1995-2000 Stage post-doctoral et première assistante à l'Université de Lausanne, Suisse
2001 Maître assistante à l'Université de Lausanne
2001-2005 Chargée de cours à l'École Polytechnique Fédérale de Lausanne, Suisse
2005 Directrice de Recherche CNRS (DR2) au Centre de Biophysique Moléculaire - CNRS, Orléans, France
2013 Promotion DR1
2012 - Directrice du Centre de Biophysique Moléculaire (140 personnes)
DISTINCTIONS
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1990 Prix de la Faculté des Sciences, Université de Debrecen, Hongrie
2018 Médaille d'argent du CNRS
ACTIVITÉS DE RECHERCHE
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Conception, synthèse et caractérisation de nouvelles sondes à base de complexes de lanthanides pour l'imagerie biomédicale
Auteur de 162 publications dans des journaux internationaux, 14 chapitres de livre, 3 brevets.
Co-editeur du livre "The Chemistry of Contrats Agents in Medical Magnetic Resonance Imaging" (Wiley & sons 2001 (1st edition), 2013 (2nd edition). h-factor: 50.
78 invited conferences and seminars.
ACTIVITÉS DE FORMATION
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Direction de 14 thèses, 6 post-docs
Accueil de 28 étudiants et post-doctorants en échange ; 6 professeurs invités
Enseignement au Master International "Bioimaging" Paris Descartes (2011- )
RESPONSABILITÉS SCIENTIFIQUES - ACTIVITÉS DE MANAGEMENT
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- Chair du réseau européen COST D38 "Metal-based systems for molecular imaging applications" (2008-2012 ; 50 laboratoires participants) ; Grant holder de l'Action COST TD1004 "Theranostics " (2012-2015)
- Directrice du Groupement de Recherche (GDR) "Agents d'Imagerie Moléculaire" , France (~ 40 laboratoires partenaires)
- Directrice du laboratoire International Associé "MirTANGO bis" avec l'Université Jaggelon de Cracovie, Pologne (2016-2020)
- Membre de "Scientific Advisory Board" de Max Planck Institute for Biological Cybernetics, Tübingen, Germany (2008-2016)
- Membre de "Scientific Advisory Board" of Maloposka Institute of biotechnology, Cracovie, Pologne (2016 - )
- Membre du conseil Scientifique de l'Institut Multidisciplinaire Hubert Curien, Strasbourg (2011-)
- Co-coordinator of the working Group "Chemistry for probes and contrast" in France Life Imaging
- Membre de "International Advisory Board of Inorganic Chemistry" (ACS ; 2015-2017)
- Membre de "International Advisory board of ChemMedChem" (Wiley ; 2017 - )
ORGANISATION DE CONFÉRENCES
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- Final COST D18 meeting "Lanthanide Chemistry for Diagnosis and Therapy", 31 march - 1 April 2006, Orléans, France
- 1st Working Group Meeting "MRI Contrast Agents" du COST D38, Orléans, 8-9 Dec. 2006 ; 2nd Working Group Meeting "MRI Contrast Agents" du COST D38, Orléans, 29 Febr. - 1 March 2008 ; 3ème journées du groupe Polyamines, 14-16 June 2011, Orléans
- 2010-2012: Member of the Scientific Organizing Committee of the european Molecular Imaging Meeting (EMIM), responsable for "Imaging Probe Design" sessions
- Member of the Scientific Organizing Committee for Dalton discussions: Metal ions in Medical Imaging, York, Sept. 2014
- Member of the National Organizing Committee for ICC42 in Brest, France, 2016
- Convenor for the session "Methods and Application at the chemistry-Biology interface" at EuChems 2016, Sevilla
- Medical Flavour of Metal Complexes, Studium Conference, Orléans, 8-10 Dec. 2015
- Being Smart in Coordination Chemistry, Studium conference, Orléans, 26-28 Sept. 2016
- Is Multimodal Imaging an Invention with future ? The input of chemistry, Studium conference, Orléans, 11-12 Dec. 2017
- Journées scientifiques du GDR AIM, juin 2018, Orléans
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Innovative nanobody-targeted nanoplatform delivering manganese contrast agents for MRI visualization of pancreatic islet beta cellsOptimizing Imaging and Dose-Response in Radiotherapies Workshop, Canceropole Grand Ouest, Oct 2023, Erquy, France. 1 page
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Metal complexes in imaging applicationsRemise des prix de la SCF, Oct 2021, Clermont-Ferrand, France
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Complexes de manganèse pour TEP et IRM : production du 52Mn et conception de ligands pour une complexation stable et inerteJournée scientifique "Vectorisation, Imagerie, Radiothérapies" du Cancéropôle Grand Ouest, May 2021, webinar, France
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Metal complexes for amyloid detection54th Colloquium of Coordination Chemistry, May 2021, Budapest, Hungary
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Direct Monitoring of Doxorubicin Release via sensitization of NIR-emitting Ytterbium LiposomesJournées du WP "Agents d'imagerie", WP1, de FLI et du GDR AIM, Nov 2021, Grenoble, France
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Novel Bispidine-based Mn(II) complexes for PET/MR Imaging15th European Molecular Imaging Meeting, Aug 2020, Virtual, France
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Séminaire invité : Molecular imaging agents based on lanthanide complexesInstitut Parisien de Chimie Moléculaire, Mar 2019, Paris, France
Communication dans un congrès
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Séminaire invité : Molecular imaging agents based on lanthanide complexesCEA - Service de Chimie Bioorganique et de Marquage, Mar 2019, Saclay, France
Communication dans un congrès
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Enzymatic detection by MRIThe future of molecular MR - a Cellular and Molecular Imaging Workshop, Jul 2019, St. John's, Newfoundland, Canada
Communication dans un congrès
hal-03283046v1
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Responsive MRI AgentsSymposium “40 Years of MR Contrast Agents”, May 2019, Mons, Belgium
Communication dans un congrès
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Medical imaging techniques: the role of chemistry70 years of the Faculty of Sciences at the University of Debrecen, Nov 2019, Debrecen, Hungary
Communication dans un congrès
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Séminaire invité : Molecular imaging agents based on lanthanide complexesENS, Feb 2019, Paris, France
Communication dans un congrès
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Lanthanide complexes in molecular imagingConference at the Hungarian Academy of Sciences, Oct 2019, Budapest, Hungary
Communication dans un congrès
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Complexes de lanthanide comme agents d'imagerie moléculaire4e congrès de la Société Française de Résonance Magnétique en Biologie et Medicine, Mar 2019, Strasbourg, France
Communication dans un congrès
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Metal-Based Responsive MR Probes8th International Meeting of theInstitute of Metals in Biology of Grenoble, Sep 2019, Villard-de-Lans, France
Communication dans un congrès
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Séminaire invité : Molecular imaging agents based on lanthanide complexesInstitut des Sciences du Vivant Frédéric Joliot, Apr 2018, Orsay, France
Communication dans un congrès
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Séminaire invité : Molecular imaging agents based on lanthanide complexesUniversity of Coimbra, Department of Life Sciences, Dec 2018, Coimbra, Portugal
Communication dans un congrès
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Séminaire invité : Molecular imaging agents based on lanthanide complexesUniversité autonome de Barcelone, Department of Chemistry, Feb 2018, Barcelone, Spain
Communication dans un congrès
hal-03282992v1
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Responsive MRI probes based on lanthanidesBracco Workshop “Advances in the Inorganic chemistry of MRI probes for contrast Enhancement”, Oct 2018, Milan, Italy
Communication dans un congrès
hal-03283074v1
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MRI contrast agents and responsive probesXXIIIrd International Krutyn Summer School “Advanced Lanthanide Molecules and Materials for Bioimaging and Medical Diagnostics: State of the Art”, May 2018, Krutyń, Masurian Lake District, Poland
Communication dans un congrès
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Lanthanide-Based Probes in Molecular ImagingFrenchBIC 2018, Oct 2018, Carry-le-Rouet, France
Communication dans un congrès
hal-03283153v1
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Chemistry for Magnetic Resonance ImagingFrench-Hungarian bilateral research conference, Sep 2018, Budapest, Hungary
Communication dans un congrès
hal-03283068v1
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Lanthanide-Based Responsive Probes for Magnetic Resonance Imaging - keynote lecture10th International Conference on f-Elements, Sep 2018, Lausanne, Switzerland
Communication dans un congrès
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MRI in neuroscienceMolecular imaging and chemistry: defining the future, Mar 2017, Buckinghamshire, United Kingdom
Communication dans un congrès
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Séminaire invité : Molecular imaging agents based on lanthanide complexesUniversité de Rouen, May 2017, Rouen, France
Communication dans un congrès
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Molecular Imaging Agents Based on Lanthanide Complexes1st Meeting of the LIA “Mir-TANGo” bis, Jun 2017, Cracovie, Poland
Communication dans un congrès
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Séminaire invité : Molecular imaging agents based on lanthanide complexesUniversité de Manchester, School of Chemistry, Nov 2017, Manchester, United Kingdom
Communication dans un congrès
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Molecular Imaging Agents Based on Lanthanide Complexes1st Meeting of the LIA “Mir-TANGo” bis, Jun 2017, Cracovie, Poland
Communication dans un congrès
hal-03283216v1
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Strategies to increase sensitivity of MRI contrast agents - Strategies to modulate efficiency: responsive probesInternational Symposium “Molecular imaging agents in medicine”, Feb 2017, Groningen, Netherlands
Communication dans un congrès
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Agents de contraste intelligents pour la detection du zinc par IRMJournées de Chimie de Coordination, Jan 2017, Grenoble, France
Communication dans un congrès
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Séminaire invité : Molecular imaging agents based on lanthanide complexesUniversité d’Uppsala, Department of Chemistry, Oct 2017, Uppsala, Sweden
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Molecular imaging agents based on lanthanide complexes – invited plenary lectureRICT 2016 Interfacing Chemical Biology and Drug Discovery, Jul 2016, Caen, France
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Molecular imaging agents based on lanthanide complexes - keynote lecture16th European Biological Inorganic Chemistry Conference – EuroBIC-16, Aug 2016, Budapest, Hungary
Communication dans un congrès
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Apport de la chimie pour les agents de contraste IRM pour l’imagerie de l’infection bactérienneAtelier FLI/IDMIT « Imagerie de l’infection et de l’inflammation », May 2016, Paris, France
Communication dans un congrès
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Responsive and Multimodal Imaging Probes Based on Lanthanide Complexes3rd European Colloquium on Inorganic Reaction Mechanisms, Jun 2016, Cracovie, Poland
Communication dans un congrès
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Molecular Imaging Agents Based on Lanthanide Complexes3rd Meeting of the LIA “Mir-TANGo”, May 2016, Orléans, France
Communication dans un congrès
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Lanthanide Containing Nanoparticles in Theranostic ApproachesLe Studium conference “Medicinal flavor of metal complexes: diagnostic and therapeutic applications”, Sep 2016, Orléans, France
Communication dans un congrès
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Lanthanide Containing Nanoparticles in Theranostic Approaches42nd International Conference on Coordination Chemistry, Jul 2016, Brest, France
Communication dans un congrès
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Lanthanide-based molecular imaging agentsFrench-Czech Vltava Chemistry Meeting, Sep 2016, Orléans, France
Communication dans un congrès
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SPECT / MRI quantitative detection of zinc using a cocktail of 165Er(III) and Gd(III) complexes14th European Molecular Imaging Meeting, Mar 2019, Glasgow, United Kingdom
Poster de conférence
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GRPr-Targeted Gold Nanoparticles for Multimodal Imaging13th European Molecular Imaging Meeting, Mar 2018, San Sebastien, Spain
Poster de conférence
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MRI contrast agents for quantitative zinc detectionGDR Agents d’Imagerie Moléculaire (AIM), Jun 2018, Orléans, France
Poster de conférence
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X-ray-induced radiophotodynamic therapy (RPDT) using lanthanide micelles: Beyond depth limitations12th annual meeting of the European Society for Molecular Imaging – ESMI, Apr 2017, Cologne, Germany
Poster de conférence
hal-02453469v1
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Gold Nanoprobe for Translational Multimodal imagingLe Studium conference “Is Multimodal Imaging an invention with a future? The input of chemistry”, Dec 2017, Orléans, France
Poster de conférence
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X-ray-induced radiophotodynamic therapy (RPDT) using lanthanide micelles: Beyond depth limitationsSFNano Annual Meeting 2016, Dec 2016, Paris, France
Poster de conférence
hal-02453468v1
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Zinc responsive contrast agentsInternational Conference on Coordination Chemistry (ICCC), Jul 2016, Brest, France
Poster de conférence
hal-03300659v1
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Smart MRI contrast agents for zinc detectionLe Studium conférence “Being smart in coordination chemistry: Medical Applications”, Sep 2016, Orléans, France
Poster de conférence
hal-03300683v1
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X-ray-induced radiophotodynamic therapy (RPDT) using lanthanide micelles: Beyond depth limitations6th EuCheMS Chemistry Congress, Sep 2016, Seville, Spain
Poster de conférence
hal-03300671v1
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Smart MRI contrast agents for zinc detectionColloque association des doctorants du CBM, Feb 2016, Orléans, France
Poster de conférence
hal-03300628v1
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Transition metal-based MRI relaxation agents (Mn and Fe)Advances in Inorganic Chemistry: Recent Highlights, 78, 2021, 9780323851152
Chapitre d'ouvrage
hal-03549862v1
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Des agents intelligents pour l'imageriePradier C.-M., Parisel O., Teyssandier F. Etonnante chimie : Découvertes et promesses du XXIème siècle, CNRS Editions, pp.230-235, 2021, 9782271136527
Chapitre d'ouvrage
hal-03638357v1
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MRI relaxation agents based on transition metalsColin D. Hubbard; Rudi van Eldik. Advances in Inorganic Chemistry: Recent Highlights I, 78, Elsevier, pp.109-142, 2021, Advances in Inorganic Chemistry, 978-0-323-85115-2. ⟨10.1016/bs.adioch.2021.06.001⟩
Chapitre d'ouvrage
hal-03812422v1
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Manganese Complexes as Contrast Agents for Magnetic Resonance ImagingAstrid Sigel Eva Freisinger and Roland K.O. Sigel. Metal Ions in Bio-Imaging Techniques, De Gruyter, pp.71-100, 2021, 9783110685565. ⟨10.1515/9783110685701-009⟩
Chapitre d'ouvrage
hal-03549867v1
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"Dual Imaging Gold Nanoplatforms for Targeted Radiotheranostics"Prime Archives in Material Science, 2020, 978-93-90014-26-2
Chapitre d'ouvrage
hal-03549858v1
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Molecular Probes for Magnetic Resonance Imaging of Amyloid β PeptidesReference Module in Chemistry, Molecular Sciences and Chemical Engineering, Elsevier, 2018, 9780124095472. ⟨10.1016/B978-0-12-409547-2.13926-5⟩
Chapitre d'ouvrage
hal-02080790v1
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Molecular Magnetic Resonance Imaging Probes Based on Ln3+ ComplexesAdvances in Inorganic Chemistry, pp.43-96, 2016, ⟨10.1016/bs.adioch.2015.09.002⟩
Chapitre d'ouvrage
hal-02081246v1
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Metal Complexes as MRI Contrast Enhancement AgentsReference Module in Chemistry, Molecular Sciences and Chemical Engineering, Elsevier, 2015, 978-0-12-409547-2. ⟨10.1016/B978-0-12-409547-2.11263-6⟩
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MRI Contrast AgentsLigand Design in Medicinal Inorganic Chemistry, John Wiley & Sons, Ltd, pp.321-354, 2014, ⟨10.1002/9781118697191.ch12⟩
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Responsive ProbesMerbach Andre S., Helm Lothar, Tóth Eva. The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging, John Wiley & Sons, pp.343-385, 2013, 978-1-119-99176-2
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Relaxivity of Gadolinium(III) Complexes: Theory and MechanismThe Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging, Second Edition, John Wiley & Sons, Ltd, pp.25-81, 2013, ⟨10.1002/9781118503652.ch2⟩
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MRI Contrast Agents, In Supramolecular Chemistry : From Molecules to NanomaterialsJonathan W. Steed, Philip A. Gale. Self-Assembly and Supramolecular Devices, 5, John Wiley & Sons, Ltd, pp.2693-2723, 2012, 978-0-470-74640-0. ⟨10.1002/9780470661345.Smc104⟩
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Gadolinium-Based Bionanomaterials for Magnetic Resonance ImagingBALAJI SITHARAMAN. Nanobiomaterials Handbook, CRC Press, pp.1-34, 2011, ⟨10.1201/b10970-19⟩
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Metal Complexes as MRI Contrast Enhancement AgentsJon A. Mc Cleverty, J. Thomas. Compréhensive Coordination Chemistry II, 9, Elsevier, pp.841-881, 2004
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Lanthanide ions as magnetic resonance imaging agents. Nuclear and electronic relaxation properties. Applications.Metal Ionsin Biological Systems, 40 (15), Marcel Dekker INC., pp.589-642, 2003
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Relaxivity of MRI Contrast AgentsTopics in Current Chemistry, 221 (2), pp.61-101, 2002, 978-3-540-42247-1
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Particles Comprising Luminescent Lanthanide ComplexesFrance, Patent n° : 13305291.0. 2014
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