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Involvement of an Arginine Triplet in M1 Matrix Protein Interaction with Membranes and in M1 Recruitment into Virus-Like Particles of the Influenza A(H1N1)pdm09 Virus

Adeline Kerviel , Shantoshini Dash , Olivier Moncorgé , Baptiste Panthu , Jan Prchal , et al.
PLoS ONE, 2016, 11 (11), pp.e0165421. ⟨10.1371/journal.pone.0165421⟩
Article dans une revue hal-01871552v1
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The viral capping enzyme nsP1: a novel target for the inhibition of chikungunya virus infection

L. Delang , C. Li , A. Tas , G. Querat , I. C. Albulescu , et al.
Scientific Reports, 2016, 6, pp.31819. ⟨10.1038/srep31819⟩
Article dans une revue hal-01439113v1
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Interaction of human immunodeficiency virus type 1 Vif with Gag and Gag-Pol precursors : co-encapsidation and interference with viral protease-mediated Gag processing

Martine Bardy , Bernard Gay , Stéphanie Pébernard , Nathalie Chazal , Marianne Courcoul , et al.
Journal of General Virology, 2001, 82, pp.2719-2733. ⟨10.1099/0022-1317-82-11-2719⟩
Article dans une revue hal-02147214v1

Crystallization and diffraction analysis of the SARS coronavirus nsp10-nsp16 complex.

Claire Debarnot , Isabelle Imbert , Francois Ferron , Laure Gluais , Isabelle Varlet , et al.
Acta crystallographica Section F : Structural biology communications [2014-..], 2011, 67 (Pt 3), pp.404-8. ⟨10.1107/S1744309111002867⟩
Article dans une revue hal-00751530v1
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A N7-guanine RNA cap methyltransferase signature-sequence as a genetic marker of large genome, non-mammalian Tobaniviridae

Francois Ferron , Humberto Julio Debat , Ashleigh Shannon , Etienne Decroly , Bruno Canard
NAR Genomics and Bioinformatics, 2020, 2 (1), ⟨10.1093/nargab/lqz022⟩
Article dans une revue hal-02890583v1
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Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex

Daniel L Hurdiss , Priscila El Kazzi , Lisa Bauer , Nicolas Papageorgiou , Francois Ferron , et al.
Science Advances , 2022, 8 (1), ⟨10.1126/sciadv.abj7615⟩
Article dans une revue hal-03572836v1

Filovirus proteins for antiviral drug discovery: A structure/function analysis of surface glycoproteins and virus entry

Baptiste Martin , Thomas Hoenen , Bruno Canard , Etienne Decroly
Antiviral Research, 2016, 135, pp.1-14. ⟨10.1016/j.antiviral.2016.09.001⟩
Article dans une revue hal-01439094v1
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Interplay of RNA 2′-O-methylations with viral replication

Alice Decombe , Priscila El Kazzi , Etienne Decroly
Current Opinion in Virology, 2023, 59 (avril), pp.101302. ⟨10.1016/j.coviro.2023.101302⟩
Article dans une revue hal-03981798v1
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Mutations on VEEV nsP1 relate RNA capping efficiency to ribavirin susceptibility

Nadia Rabah , Oney Ortega Granda , Gilles Quérat , Bruno Canard , Etienne Decroly , et al.
Antiviral Research, 2020, 182, pp.104883. ⟨10.1016/j.antiviral.2020.104883⟩
Article dans une revue hal-03030827v1

mRNA Capping by Venezuelan Equine Encephalitis Virus nsP1: Functional Characterization and Implications for Antiviral Research

Changqing Li , Jaime Guillen , Nadia Rabah , Alexandre Blanjoie , Francoise Debart , et al.
Journal of Virology, 2015, 89 (16), pp.8292-8303. ⟨10.1128/JVI.00599-15⟩
Article dans une revue hal-01439035v1
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The methyltransferase domain of the Respiratory Syncytial Virus L protein catalyzes cap N7 and 2’-O-methylation

Priscila Sutto-Ortiz , Sergey Tcherniuk , Nina Ysebaert , Pravien Abeywickrema , Mathieu Noël , et al.
PLoS Pathogens, 2021, 17 (5), pp.1-20. ⟨10.1371/journal.ppat.1009562⟩
Article dans une revue hal-03282037v1
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Binding of the Methyl Donor S -Adenosyl-l-Methionine to Middle East Respiratory Syndrome Coronavirus 2′- O -Methyltransferase nsp16 Promotes Recruitment of the Allosteric Activator nsp10

Wahiba Aouadi , Alexandre Blanjoie , Jean-Jacques Vasseur , Françoise Debart , Bruno Canard , et al.
Journal of Virology, 2017, 91 (5), pp.1103-1119. ⟨10.1128/JVI.02217-16⟩
Article dans une revue hal-01802788v1

Reevaluation of possible outcomes of infections with human immunodeficiency virus

C. Tamalet , Philippe Colson , Etienne Decroly , C. Dhiver , I. Ravaux , et al.
Clinical Microbiology and Infection, 2016, 22 (4), pp.299-311. ⟨10.1016/j.cmi.2015.11.022⟩
Article dans une revue hal-01459405v1
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Structure of the Respiratory Syncytial Virus Polymerase Complex

Morgan S A Gilman , Cheng Liu , Amy Fung , Ishani Behera , Paul Jordan , et al.
Cell, 2019, 179 (1), pp.193-204.e14. ⟨10.1016/j.cell.2019.08.014⟩
Article dans une revue hal-02353778v1

Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design

Fatiha Benmansour , Iuni Trist , Bruno Coutard , Etienne Decroly , Gilles Querat , et al.
European Journal of Medicinal Chemistry, 2017, 125, pp.865-880. ⟨10.1016/j.ejmech.2016.10.007⟩
Article dans une revue hal-02061703v1
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Identification of potent inhibitors of arenavirus and SARS-CoV-2 exoribonucleases by fluorescence polarization assay

Sergio Hernández , Mikael Feracci , Carolina Trajano de Jesus , Priscila El Kazzi , Rafik Kaci , et al.
Antiviral Research, 2022, 204, pp.105364. ⟨10.1016/j.antiviral.2022.105364⟩
Article dans une revue hal-03860671v1

Novel Class of Chikungunya Virus Small Molecule Inhibitors That Targets the Viral Capping Machinery

Rana Abdelnabi , Kristina Kovacikova , Julia Moesslacher , Kim Donckers , Verena Battisti , et al.
Antimicrobial Agents and Chemotherapy, 2020, 64 (7), ⟨10.1128/AAC.00649-20⟩
Article dans une revue hal-02890582v1
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Synthesis, Structure–Activity Relationships, and Antiviral Profiling of 1-Heteroaryl-2-Alkoxyphenyl Analogs As Inhibitors of SARS-CoV-2 Replication

Dorothée Bardiot , Laura Vangeel , Mohamed Koukni , Philippe Arzel , Marleen Zwaagstra , et al.
Molecules, 2022, 27 (3), pp.1052. ⟨10.3390/molecules27031052⟩
Article dans une revue hal-03561598v1

High-yield production of short GppA- and 7Me GppA-capped RNAs and HPLC-monitoring of methyltransfer reactions at the guanine-N7 and adenosine-2'O positions.

F. Peyrane , B. Selisko , Etienne Decroly , J.-J. Vasseur , D. Benarroch , et al.
Nucleic Acids Research, 2007, 35, pp.1-11
Article dans une revue hal-00346549v1
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First insights into the structural features of Ebola virus methyltransferase activities

Coralie Valle , Baptiste Martin , François Ferron , Véronique Roig-Zamboni , Aline Desmyter , et al.
Nucleic Acids Research, 2021, 49 (3), pp.1737 - 1748. ⟨10.1093/nar/gkaa1276⟩
Article dans une revue hal-03334409v1
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Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives

Bruno Coutard , Karine Barral , Julie Lichiere , Barbara Selisko , Baptiste Martin , et al.
Journal of Virology, 2017, 91 (5), pp.2202-2218. ⟨10.1128/JVI.02202-16⟩
Article dans une revue hal-01802793v1
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The C-Terminal Domain of the Sudan Ebolavirus L Protein Is Essential for RNA Binding and Methylation

Coralie Valle , Baptiste Martin , Françoise Debart , Jean-Jacques Vasseur , Isabelle Imbert , et al.
Journal of Virology, 2020, 94 (12), pp.e00520-20. ⟨10.1128/JVI.00520-20⟩
Article dans une revue hal-02890587v1
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2C protein of Enterovirus: key protein of viral replication and antiviral target

Priscila El Kazzi , Carole Yaacoub , Ziad Fajloun , Patrice Vanelle , Etienne Decroly , et al.
Virologie, 2023, 27 (3), pp.35-49. ⟨10.1684/vir.2023.1002⟩
Article dans une revue hal-04252121v1
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Design, Synthesis and Discovery of N,N’ ‐Carbazoyl‐aryl‐urea Inhibitors of Zika NS5 Methyltransferase and Virus Replication

Sharon Spizzichino , Giulio Mattedi , Kate Lauder , Coralie Valle , Wahiba Aouadi , et al.
ChemMedChem, 2020, 15 (4), pp.385-390. ⟨10.1002/cmdc.201900533⟩
Article dans une revue hal-02890596v1
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A Versatile Class of 1,4,4-Trisubstituted Piperidines Block Coronavirus Replication In Vitro

Sonia de Castro , Annelies Stevaert , Miguel Maldonado , Adrien Delpal , Julie Vandeput , et al.
Pharmaceuticals, 2022, 15 (8), pp.1021. ⟨10.3390/ph15081021⟩
Article dans une revue hal-03937322v1

Dengue Virus NS5 Transcribes Metabolite-Capped, RIG-I Sensitive vRNAs

Brandon Schweibenz , Mihai Solotchi , Etienne Decroly , Barbara Selisko , Bruno Canard , et al.
Biophysical Journal, 2021, 120 (3), pp.135a. ⟨10.1016/j.bpj.2020.11.1017⟩
Article dans une revue hal-03426114v1
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Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication

Natacha S Ogando , Priscila El Kazzi , Clara C Posthuma , Volker Thiel , Bruno Canard , et al.
2021
Pré-publication, Document de travail hal-03426119v1

Assessment of Dengue virus helicase and methyltransferase as targets for fragment-based drug discovery

Bruno Coutard , Etienne Decroly , Changqing Li , Andrew Sharff , Julien Lescar , et al.
Antiviral Research, 2014, 106, pp.61-70. ⟨10.1016/j.antiviral.2014.03.013⟩
Article dans une revue hal-02061701v1

To something, Covid is good: SFV 2.0

Grégory Caignard , Etienne Decroly , Maria Dimitrova , David Gilmer , Anne-Sophie Gosselin-Grenet , et al.
Virologie, 2020, 24 (3), pp.133-134. ⟨10.1684/vir.2020.0846⟩
Article dans une revue hal-02979056v1
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The methyltransferase domain of dengue virus protein NS5 ensures efficient RNA synthesis initiation and elongation by the polymerase domain

Supanee Potisopon , Stéphane Priet , Axelle Collet , Etienne Decroly , Bruno Canard , et al.
Nucleic Acids Research, 2014, 42 (11642-11656), ⟨10.1093/nar/gku666⟩
Article dans une revue hal-01244874v1