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Researcher identifiers

Number of documents

14

INGENIEUR CHERCHEUR CEA


Lieu de travail :

 Laboratoire Structure & Dynamique par Résonance Magnétique (LSDRM) IRAMIS/NIMBE, UMR CEA/CNRS 3685 CEA Saclay 91191 Gif sur Yvette

Activité scientifique :

RMN et IRM du xénon hyperpolarisé pour l'étude :

  • d'échantillons cellulaires
  • de biosondes
  • de matériaux poreux

Developpement de pompage optique de gaz rare (mobile)

 

Microfluidique pour la RMN en flux


T. Brotin   

Journal articles11 documents

  • Emilie Mari, Yasmina Bousmah, Céline Boutin, Estelle Léonce, Gaëlle Milanole, et al.. Bimodal detection of proteins by $^{129}$Xe NMR and fluorescence spectroscopy. ChemBioChem, Wiley-VCH Verlag, In press, 20, pp.1450-1457. ⟨10.1002/cbic.201800802⟩. ⟨cea-01988479⟩
  • Dawei Zhang, Tanya K. Ronson, Jake L. Greenfield, Thierry Brotin, Patrick Berthault, et al.. Enantiopure [Cs$^+$/Xe$\subset$Cryptophane]$\subset$Fe$^{II}$$_4$L$_4$ Hierarchical Superstructures. Journal of the American Chemical Society, American Chemical Society, 2019, 141 (20), pp.8339-8345. ⟨10.1021/jacs.9b02866⟩. ⟨cea-02117134⟩
  • Orsola Baydoun, Nicolas de Rycke, Estelle Léonce, Céline Boutin, Patrick Berthault, et al.. Synthesis of Cryptophane-223-Type Derivatives with Dual Functionalization. Journal of Organic Chemistry, American Chemical Society, 2019, 84, pp.9127-9137. ⟨10.1021/acs.joc.9b01093⟩. ⟨cea-02183121⟩
  • Patrick Berthault, Estelle Léonce, Jean-Pierre Dognon, Delphine Pitrat, Jean-Christophe Mulatier, et al.. Accurate pH sensing via hyperpolarized $^{129}$Xe NMR. Chemistry - A European Journal, Wiley-VCH Verlag, In press, 24, pp.6534-6537. ⟨10.1002/chem.201800900⟩. ⟨cea-01720386⟩
  • Thierry Brotin, Erwann Jeanneau, Patrick Berthault, Estelle Léonce, Delphine Pitrat, et al.. Synthesis of Cryptophane-B. Crystal Structure and Study of its Complex with Xenon.. Journal of Organic Chemistry, American Chemical Society, 2018, 83, pp.14465-14471. ⟨10.1021/acs.joc.8b02246⟩. ⟨cea-01922217⟩
  • Patrick Berthault, Céline Boutin, Estelle Léonce, Erwann Jeanneau, Thierry Brotin. Role of the Methoxy Groups in Cryptophanes for Complexation of Xenon. Conformational Selection Evidenced by 129 Xe-1 H NMR SPINOE Experiments. ChemPhysChem, Wiley-VCH Verlag, 2017, 18, pp.1561-1568. ⟨10.1002/cphc.201700266⟩. ⟨cea-01510320⟩
  • Gaëlle Milanole, Bo Gao, Audrey Paoletti, Grégory Pieters, Christophe Dugave, et al.. Bimodal Fluorescence/{129}Xe NMR Probe for Molecular Imaging and Biological Inhibition of EGFR in Non-Small Cell Lung Cancer. Bioorganic and Medicinal Chemistry, Elsevier, 2017, 25, pp.6653-6660. ⟨10.1016/j.bmc.2017.11.002⟩. ⟨cea-01630103⟩
  • Gaspard Huber, Estelle Léonce, Orsola Baydoun, Nicolas de Rycke, Thierry Brotin, et al.. Unsaturated cryptophanes: toward dual PHIP/hyperpolarised xenon sensors. Magnetic Resonance in Chemistry, Wiley, In press, 56, pp.672-678. ⟨10.1002/mrc.4691⟩. ⟨cea-01660523⟩
  • Nawal Tassali, Naoko Kotera, Céline Boutin, Estelle Léonce, Yves Boulard, et al.. Smart Detection of Toxic Metal Ions, Pb2+ and Cd2+, Using a 129Xe NMR-Based Sensor. Analytical and Bioanalytical Chemistry, Springer Verlag, 2014, 86 (3), pp.1783-1788. ⟨10.1021/ac403669p⟩. ⟨hal-01117441⟩
  • Céline Boutin, Estelle Léonce, Thierry Brotin, Alexej Jerschow, Patrick Berthault. Ultrafast Z-Spectroscopy for 129 Xe NMR-Based Sensors. Journal of Physical Chemistry Letters, American Chemical Society, 2013, 4 (23), pp.4172 - 4176. ⟨10.1021/jz402261h⟩. ⟨hal-01896791⟩
  • Naoko Kotera, Nawal Tassali, Estelle Léonce, Céline Boutin, Patrick Berthault, et al.. A Sensitive Zinc-Activated 129Xe MRI Probe. Angewandte Chemie International Edition, Wiley-VCH Verlag, 2012, 51 (17), pp.4100-4103. ⟨10.1002/anie.201109194⟩. ⟨hal-01117150⟩

Conference papers1 document

  • Céline Boutin, Estelle Léonce, Emilie Mari, Guillaume Carret, Emmanuelle Dubost, et al.. Dernières avancées sur l'utilisation du xénon polarisé comme biosonde. GERM 2014 (Groupe d’Etude de Résonance Magnétique), Jun 2014, Biarritz, France. ⟨cea-02361804⟩

Poster communications2 documents

  • Estelle Léonce, Thierry Brotin, Jean-Pierre Dognon, Patrick Berthault. Accurate determination of pH via hyperpolarized $^{129}$Xe NMR. 39th FGMR Annual Discussion Meeting, Sep 2017, Bayreuth, Germany. ⟨cea-02341010⟩
  • Emilie Mari, Naoko Kotera, E. Dubost, Gaëlle Milanole, Eric Doris, et al.. A doubly responsive probe for the detection of Cys4-tagged proteins. International Symposium XeMAT 2015, Sep 2015, Dresden, Germany. ⟨cea-02356699⟩