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Fluorescence intercalator displacement assay for screening G4 ligands towards a variety of G-quadruplex structures

 Phong Lan Thao Tran , Eric Largy , Florian Hamon , Marie-Paule Teulade-Fichou , Jean-Louis Mergny
Biochimie, 2011, 93 (8), pp.1288-1296. ⟨10.1016/j.biochi.2011.05.011⟩
Article dans une revue istex mnhn-02619114v1
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An Acyclic Oligoheteroaryle That Discriminates Strongly between Diverse G-Quadruplex Topologies

 Florian Hamon , Eric Largy , Aurore Guødin-Beaurepaire , Myriam Rouchon-Dagois , Assitan Sidibe , et al.
Angewandte Chemie International Edition, 2011, 50 (37), pp.8745-8749. ⟨10.1002/anie.201103422⟩
Article dans une revue istex hal-02125709v1
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Role of Alkali Metal Ions in G-Quadruplex Nucleic Acid Structure and Stability

 Eric Largy , Jean-Louis Mergny , Valérie Gabelica
The Alkali Metal Ions: Their Role for Life, Springer Verlag (Germany), pp.203-258, 2016, ⟨10.1007/978-3-319-21756-7_7⟩
Chapitre d'ouvrage hal-01524114v1
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Design, synthesis, and antiproliferative effect of 2,9‐bis[4‐(pyridinylalkylaminomethyl)phenyl]‐1,10‐phenanthroline derivatives on human leukemic cells by targeting G‐quadruplex

 Jean Guillon , Caroline Denevault‐sabourin , Edith Chevret , Marie Brachet‐botineau , Vittoria Milano , et al.
Archiv der Pharmazie / Chemistry in Life Sciences, 2021, 354, pp.e2000450. ⟨10.1002/ardp.202000450⟩
Article dans une revue hal-03279625v1
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Quadruplex Turncoats: Cation-Dependent Folding and Stability of Quadruplex-DNA Double Switches

 Eric Largy , Adrien Marchand , Samir Amrane , Valérie Gabelica , Jean-Louis Mergny
Journal of the American Chemical Society, 2016, 138 (8), pp.2780-2792. ⟨10.1021/jacs.5b13130⟩
Article dans une revue hal-01524154v1
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Mass Spectrometry of Nucleic Acid Noncovalent Complexes

 Eric Largy , Alexander König , Anirban Ghosh , Debasmita Ghosh , Sanae Benabou , et al.
Chemical Reviews, In press, ⟨10.1021/acs.chemrev.1c00386⟩
Article dans une revue hal-03410847v1
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IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates

 Lyssia Belarif , Caroline Mary , Lola Jacquemont , Hoa Le Mai , Richard Danger , et al.
Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-06804-y⟩
Article dans une revue inserm-02023397v1
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A two-quartet G-quadruplex topology of human KIT2 is conformationally selected by a perylene derivative

 Silvia Ceschi , Eric Largy , Valérie Gabelica , Claudia Sissi
Biochimie, 2020, 179, pp.77-84. ⟨10.1016/j.biochi.2020.09.015⟩
Article dans une revue hal-03321840v1
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Native Hydrogen/Deuterium Exchange Mass Spectrometry of Struc- tured DNA Oligonucleotides

 Eric Largy , Valérie Gabelica
Analytical Chemistry, 2020, 92 (6), pp.4402-4410. ⟨10.1021/acs.analchem.9b05298⟩
Article dans une revue hal-02882153v1
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Native Electrospray Ionization of Multi-Domain Proteins via a Bead Ejection Mechanism

 Nina Khristenko , Frédéric Rosu , Eric Largy , Jérôme Haustant , Cédric Mesmin , et al.
Journal of the American Chemical Society, 2023, 145 (1), pp.498 - 506. ⟨10.1021/jacs.2c10762⟩
Article dans une revue hal-04119433v1
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DNA G-quadruplexes for native mass spectrometry in potassium: a database of validated structures in electrospray-compatible conditions

 Anirban Ghosh , Eric Largy , Valérie Gabelica
Nucleic Acids Research, 2021, 49 (4), pp.2333 - 2345. ⟨10.1093/nar/gkab039⟩
Article dans une revue hal-03321816v1
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Design, Synthesis, and Antiprotozoal Evaluation of New Promising 2,9-Bis[(substituted-aminomethyl)]-4,7-phenyl-1,10phenanthroline Derivatives, a Potential Alternative Scaffold to Drug Efflux

 Jean Guillon , Anita Cohen , Clotilde Boudot , Sarah Monic , Solène Savrimoutou , et al.
Pathogens, 2022, 11 (11), pp.1339. ⟨10.3390/pathogens11111339⟩
Article dans une revue inserm-03850360v1
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New 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinazoline and 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinoline derivatives: synthesis and biological evaluation as novel anticancer agents by targeting G-quadruplex

 Jean Guillon , Marc Le Borgne , Vittoria Milano , Aurore Guédin-Beaurepaire , Stéphane Moreau , et al.
Pharmaceuticals, 2024, 17 (1), pp.30. ⟨10.3390/ph17010030⟩
Article dans une revue hal-04390485v1
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