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How good are the current models of adrenocortical carcinoma for novel drug discovery?

Carmen Ruggiero , Mabrouka Doghman-Bouguerra , Enzo Lalli
Expert Opinion on Drug Discovery, 2021, pp.1-3. ⟨10.1080/17460441.2022.1993817⟩
Article dans une revue hal-03538518v1
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ER-mitochondria interactions: Both strength and weakness within cancer cells

Mabrouka Doghman-Bouguerra , Enzo Lalli
Biochimica et Biophysica Acta - Molecular Cell Research, 2019, 1866 (4), pp.650-662. ⟨10.1016/j.bbamcr.2019.01.009⟩
Article dans une revue hal-02408469v1

Identification and characterization of steroidogenic factor-1 inverse agonists.

Mabrouka Doghman , Franck Madoux , Peter Hodder , Enzo Lalli
Methods in Enzymology, 2010, 485, pp.3-23. ⟨10.1016/B978-0-12-381296-4.00001-4⟩
Article dans une revue hal-00731014v1

A matter of dosage: SF-1 in adrenocortical development and cancer.

M. Doghman , E. Lalli
Annales d'Endocrinologie, 2009, 70 (3), pp.148-52. ⟨10.1016/j.ando.2009.02.002⟩
Article dans une revue hal-00417318v1
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Establishment of a mouse xenograft model of metastatic adrenocortical carcinoma

Aurélie Morin , Carmen Ruggiero , Estelle Robidel , Mabrouka Doghman-Bouguerra , Atze T. Das , et al.
Oncotarget, 2017
Article dans une revue hal-01788404v1

Nephroblastoma overexpressed/cysteine-rich protein 61/connective tissue growth factor/nephroblastoma overexpressed gene-3 (NOV/CCN3), a selective adrenocortical cell proapoptotic factor, is down-regulated in childhood adrenocortical tumors.

Mabrouka Doghman , Malika Arhatte , Hélène Thibout , Giovanna Rodrigues , Juliana de Moura , et al.
Journal of Clinical Endocrinology and Metabolism, 2007, 92 (8), pp.3253-60. ⟨10.1210/jc.2007-0342⟩
Article dans une revue hal-00172065v1

Potent inhibitory effect of the cyclolignan picropodophyllin (PPP) on human adrenocortical carcinoma cells proliferation.

Mabrouka Doghman , Magnus Axelson , Enzo Lalli
American Journal of Cancer Research, 2011, 1 (3), pp.356-361
Article dans une revue hal-00728060v1
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Integrative genomic analysis reveals a conserved role for prolactin signalling in the regulation of adrenal function

Carmen Ruggiero , Barbara Altieri , Edith Arnold , Lourdes Siqueiros-Marquez , Mabrouka Doghman-Bouguerra , et al.
Clinical and Translational Medicine, 2021, 11 (11), pp.e630. ⟨10.1002/ctm2.630⟩
Article dans une revue hal-03469274v1

Differential effects of high and low steroidogenic factor-1 expression on CYP11B2 expression and aldosterone production in adrenocortical cells.

Ping Ye , Yashuhiro Nakamura , Enzo Lalli , William E Rainey
Endocrinology, 2009, 150 (3), pp.1303-9. ⟨10.1210/en.2008-0667⟩
Article dans une revue hal-00417294v1

The orphan nuclear receptor DAX1 is up-regulated by the EWS/FLI1 oncoprotein and is highly expressed in Ewing tumors.

Marta Mendiola , Jaime Carrillo , Eva García , Enzo Lalli , Teresa Hernández , et al.
International Journal of Cancer, 2006, 118 (6), pp.1381-9. ⟨10.1002/ijc.21578⟩
Article dans une revue hal-00172274v1

Adrenal cancer: scientific advances.

Gary D Hammer , Martin Fassnacht , Enzo Lalli
Molecular and Cellular Endocrinology, 2012, 351 (1), pp.1. ⟨10.1016/j.mce.2011.11.010⟩
Article dans une revue istex hal-00728025v1

Increased incidence of choroid plexus carcinoma due to the germline TP53 R337H mutation in southern Brazil.

Gislaine Custodio , Guilherme R Taques , Bonald C Figueiredo , Elizabeth S Gugelmin , Mirna M Oliveira Figueiredo , et al.
PLoS ONE, 2011, 6 (3), pp.e18015. ⟨10.1371/journal.pone.0018015⟩
Article dans une revue hal-00731004v1
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Reduction of Fmr1 mRNA Levels Rescues Pathological Features in Cortical Neurons in a Model of FXTAS

Malgorzata Drozd , Sébastien Delhaye , Thomas Maurin , Sara Castagnola , Mauro Grossi , et al.
Molecular Therapy - Nucleic Acids, 2019, 18, pp.546-553. ⟨10.1016/j.omtn.2019.09.018⟩
Article dans une revue hal-02390850v1

Inhibition of adrenocortical carcinoma cell proliferation by steroidogenic factor-1 inverse agonists.

Mabrouka Doghman , Julie Cazareth , Dominique Douguet , Franck Madoux , Peter Hodder , et al.
Journal of Clinical Endocrinology and Metabolism, 2009, 94 (6), pp.2178-83. ⟨10.1210/jc.2008-2163⟩
Article dans une revue hal-00417317v1

Targeting the multidrug transporter Patched potentiates chemotherapy efficiency on adrenocortical carcinoma in vitro and in vivo

Anida Hasanovic , Carmen Ruggiero , Sara Jung , Ida Rapa , Laurie Signetti , et al.
International Journal of Cancer, 2018, 143 (1), pp.199-211. ⟨10.1002/ijc.31296⟩
Article dans une revue hal-02322068v1

SF-1 overexpression in childhood adrenocortical tumours.

Mara a D Pianovski , Luciane R Cavalli , Bonald C Figueiredo , Savana C L Santos , Mabrouka Doghman , et al.
European Journal of Cancer, 2006, 42 (8), pp.1040-3. ⟨10.1016/j.ejca.2006.01.022⟩
Article dans une revue istex hal-00172257v1
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The Prognostic Role of CD8 + T Lymphocytes in Childhood Adrenocortical Carcinomas Compared to Ki-67, PD-1, PD-L1, and the Weiss Score

Ivy Zortéa S. Parise , Guilherme A Parise , Lúcia Noronha , Mirvat Surakhy , Thiago Demetrius Woiski , et al.
Cancers, 2019, 11 (11), pp.1730. ⟨10.3390/cancers11111730⟩
Article dans une revue inserm-02437545v1
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Cancer-testis Antigen FATE1 Expression in Adrenocortical Tumors Is Associated with A Pervasive Autoimmune Response and Is A Marker of Malignancy in Adult, but Not Children, ACC

Mabrouka Doghman-Bouguerra , Pascal Finetti , Nelly Durand , Ivy Zortéa S Parise , Silviu Sbiera , et al.
Article dans une revue inserm-02508381v1

Efficacy of the novel dual PI3-kinase/mTOR inhibitor NVP-BEZ235 in a preclinical model of adrenocortical carcinoma.

Mabrouka Doghman , Enzo Lalli
Molecular and Cellular Endocrinology, 2012, epub ahead of print. ⟨10.1016/j.mce.2012.08.014⟩
Article dans une revue istex hal-00731029v1

Adrenal cortex remodeling and functional zona glomerulosa hyperplasia in primary aldosteronism.

Sheerazed Boulkroun , Benoit Samson-Couterie , José-Felipe Golib Dzib , Hervé Lefebvre , Estelle Louiset , et al.
Hypertension, 2010, 56 (5), pp.885-92. ⟨10.1161/HYPERTENSIONAHA.110.158543⟩
Article dans une revue hal-00731027v1

Modeling Fragile X syndrome in neurogenesis: An unexpected phenotype and a novel tool for future therapies

Barbara Bardoni , Maria Capovilla , Enzo Lalli
Neurogenesis, 2017, 4 (1), pp.e1270384. ⟨10.1080/23262133.2016.1270384⟩
Article dans une revue hal-02336005v1

FRAXE-associated mental retardation protein (FMR2) is an RNA-binding protein with high affinity for G-quartet RNA forming structure.

Mounia Bensaid , Mireille Melko , Elias G Bechara , Laetitia Davidovic , Antonio Berretta , et al.
Nucleic Acids Research, 2009, 37 (4), pp.1269-79. ⟨10.1093/nar/gkn1058⟩
Article dans une revue hal-00417259v1
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Astemizole Sensitizes Adrenocortical Carcinoma Cells to Doxorubicin by Inhibiting Patched Drug Efflux Activity.

Anida Hasanovic , Méliné Simsir , Choveau Fs , Enzo Lalli , Isabelle Mus-Veteau
Biomedicines, 2020, 8, ⟨10.3390/biomedicines8080251⟩
Article dans une revue hal-02917455v1

The Wnt/beta-catenin pathway in adrenocortical development and cancer.

Abeer El Wakil , Enzo Lalli
Molecular and Cellular Endocrinology, 2011, 332 (1-2), pp.32-7. ⟨10.1016/j.mce.2010.11.014⟩
Article dans une revue istex hal-00731010v1
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The secreted protein augurin is a novel modulator of canonical Wnt signalling involved in osteoblast differentiation

Carmen Ruggiero , Nelly Durand , Marielle Jarjat , Jacques Barhanin , Elena J Ghirardello , et al.
Clinical and Translational Discovery, 2022, 2 (3), pp.e113. ⟨10.1002/ctd2.113⟩
Article dans une revue hal-03838818v1

Clinical and molecular evidence for DAX-1 inhibition of steroidogenic factor-1-dependent ACTH receptor gene expression.

Oliver Zwermann , Felix Beuschlein , Enzo Lalli , Albrecht Klink , Paolo Sassone-Corsi , et al.
European Journal of Endocrinology, 2005, 152 (5), pp.769-76. ⟨10.1530/eje.1.01908⟩
Article dans une revue hal-00187796v1

Regulation of insulin-like growth factor-mammalian target of rapamycin signaling by microRNA in childhood adrenocortical tumors.

Mabrouka Doghman , Abeer El Wakil , Bruno Cardinaud , Emilie Thomas , Jinling Wang , et al.
Cancer Research, 2010, 70 (11), pp.4666-75. ⟨10.1158/0008-5472.CAN-09-3970⟩
Article dans une revue hal-00497713v1

Adrenocortical development and cancer: focus on SF-1.

Enzo Lalli
Journal of Molecular Endocrinology, 2010, 44 (6), pp.301-7. ⟨10.1677/JME-09-0143⟩
Article dans une revue hal-00497715v1

Heterozygous TP53stop146/R72P fibroblasts from a Li-Fraumeni syndrome patient with impaired response to DNA damage.

Juliana de Moura , Flávia Ludimila Kavalec , Mabrouka Doghman , Roberto Rosati , Gislaine Custodio , et al.
International Journal of Oncology, 2010, 36 (4), pp.983-90
Article dans une revue hal-00497745v1
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Transcriptional regulation of the glucose-6-phosphatase gene by cAMP/vasoactive intestinal peptide in the intestine. Role of HNF4alpha, CREM, HNF1alpha, and C/EBPalpha.

Amandine Gautier-Stein , Carine Zitoun , Enzo Lalli , Gilles Mithieux , Fabienne Rajas
Journal of Biological Chemistry, 2006, 281 (42), pp.31268-78. ⟨10.1074/jbc.M603258200⟩
Article dans une revue hal-00172197v1