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Coupling of D2R Short but not D2R Long receptor isoform to the Rho/ROCK signaling pathway renders striatal neurons vulnerable to mutant huntingtin
Jocelyne Caboche
,
Galan-Rodriguez Beatriz
,
Martin Elodie
,
Emmanuel ; Déglon
,
Betuing Sandrine
,
et al.
Article dans une revue
hal-03365878v1
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Impaired brain energy metabolism in the BACHD mouse model of Huntington's disease: critical role of astrocyte-neuron interactions
Lydie Boussicault
,
Anne-Sophie Herard
,
Noel Calingasan
,
Fanny Petit
,
Carole Malgorn
,
et al.
Article dans une revue
hal-01545792v1
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Calpain is a major cell death effector in selective striatal degeneration induced $in\ vivo$ by 3-nitropropionate: implications for Huntington's disease.
Nicolas Bizat
,
Jean-Michel Hermel
,
Frédéric Boyer
,
Carine Jacquard
,
Christophe Créminon
,
et al.
Journal of Neuroscience, 2003, 23 (12), pp.5020-30
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cea-02290630v1
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Time-Course of Alterations in the Endocannabinoid System after Viral-Mediated Overexpression of α-Synuclein in the Rat Brain
Rachel Kelly
,
Alexis-Pierre Bemelmans
,
Charlène Joséphine
,
Emmanuel Brouillet
,
Declan P Mckernan
,
et al.
Article dans une revue
hal-04419946v1
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Diffusion-weighted magnetic resonance spectroscopy enables cell-specific monitoring of astrocyte reactivity $in\ vivo$
Clémence Ligneul
,
Marco Palombo
,
Edwin Hernández-Garzón
,
Maria-Angeles Carrillo-de Sauvage
,
Julien Flament
,
et al.
Article dans une revue
cea-02155405v1
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CA150 expression delays striatal cell death in overexpression and knock-in conditions for mutant huntingtin neurotoxicity
Margarita Arango
,
Sébastien Holbert
,
Dania Zala
,
Emmanuel Brouillet
,
James Pearson
,
et al.
Article dans une revue
hal-02666883v1
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Mitochondria in Huntington's disease
Maria Damiano
,
Laurie Galvan
,
Nicole Déglon
,
Emmanuel Brouillet
Article dans une revue
hal-02459756v1
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Imaging and spectroscopic approaches to probe brain energy metabolism dysregulation in neurodegenerative diseases
Gilles Bonvento
,
Julien Valette
,
Julien Flament
,
Fanny Mochel
,
Emmanuel Brouillet
Article dans une revue
hal-01539753v1
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$In\ Vivo$ Calpain/Caspase Cross-talk during 3-Nitropropionic Acid-induced Striatal Degeneration
Nicolas Bizat
,
Jean-Michel Hermel
,
Sandrine Humbert
,
Carine Jacquard
,
Christophe Créminon
,
et al.
Article dans une revue
cea-02290633v1
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Energy defects in Huntington's disease: Why “in vivo” evidence matters
Géraldine Liot
,
Julien Valette
,
Jérémy Pépin
,
Julien Flament
,
Emmanuel Brouillet
Article dans une revue
hal-04476989v1
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Possible involvement of self-defense mechanisms in the preferential vulnerability of the striatum in Huntington's disease
Laetitia Francelle
,
Laurie Galvan
,
Emmanuel Brouillet
Article dans une revue
hal-02459873v1
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Striatal long noncoding RNA Abhd11os is neuroprotective against an N-terminal fragment of mutant huntingtin in vivo.
Laetitia Francelle
,
Laurie Galvan
,
Marie-Claude Gaillard
,
Fanny Petit
,
Benoît Bernay
,
et al.
Article dans une revue
hal-01465910v1
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SET translocation is associated with increase in caspase cleaved amyloid precursor protein in CA1 of Alzheimer and Down syndrome patients.
Patricia Facchinetti
,
Emilie Dorard
,
Vincent Contremoulins
,
Marie-Claude Gaillard
,
Nicole Déglon
,
et al.
Article dans une revue
hal-00946234v1
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The C-Terminal Domain of LRRK2 with the G2019S Substitution Increases Mutant A53T α-Synuclein Toxicity in Dopaminergic Neurons In Vivo
Noémie Cresto
,
Camille Gardier
,
Marie-Claude Gaillard
,
Francesco Gubinelli
,
Pauline Roost
,
et al.
Article dans une revue
hal-03452142v1
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What is gained or ‘lost in translation’ in Huntington’s disease
Emmanuel Brouillet
,
Karine Merienne
Article dans une revue
hal-03058364v1
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Corticostriatopallidal Neuroprotection by Adenovirus-Mediated Ciliary Neurotrophic Factor Gene Transfer in a Rat Model of Progressive Striatal Degeneration
Vincent Mittoux
,
Stephane Ouary
,
Christelle Monville
,
Fabrice Lisovoski
,
Thomas Poyot
,
et al.
Journal of Neuroscience, 2002, 22 (11), pp.4478-86
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cea-02290628v1
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Perseverative behavior underlying attentional set-shifting deficits in rats chronically treated with the neurotoxin 3-nitropropionic acid.
Nicole El Massioui
,
Stéphane Ouary
,
Fabrice Chéruel
,
Philippe Hantraye
,
Emmanuel Brouillet
Article dans une revue
istex
hal-01467542v1
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A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin
Maria Damiano
,
Elsa Diguet
,
Carole Malgorn
,
Marilena d'Aurelio
,
Laurie Galvan
,
et al.
Article dans une revue
hal-02459752v1
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The Mitochondrial Toxin 3-Nitropropionic Acid Induces Striatal Neurodegeneration via a c-Jun N-Terminal Kinase/c-Jun Module
Marta Garcia
,
Peter Vanhoutte
,
Christiane Pagès
,
Marie-Jo Besson
,
Emmanuel Brouillet
,
et al.
Article dans une revue
hal-02372666v1
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Ectosomes: a new mechanism for non-exosomal secretion of tau protein.
Simon Dujardin
,
Séverine Bégard
,
Raphaëlle Caillierez
,
Cédrick Lachaud
,
Lucie Delattre
,
et al.
Article dans une revue
hal-01181185v1
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Discovering new bioactive neuropeptides in the striatum secretome using in vivo microdialysis and versatile proteomics.
Benoît Bernay
,
Marie-Claude Gaillard
,
Vilém Guryca
,
Anouk Emadali
,
Lauriane Kuhn
,
et al.
Article dans une revue
inserm-00410894v1
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Contribution of Neuroepigenetics to Huntington’s Disease
Laetitia Francelle
,
Caroline Lotz
,
Tiago Outeiro
,
Emmanuel Brouillet
,
Karine Merienne
Article dans une revue
hal-03060269v1
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Contribution of Neuroepigenetics to Huntington’s Disease
Laetitia Francelle
,
Caroline Lotz
,
Tiago Outeiro
,
Emmanuel Brouillet
,
Karine Merienne
Article dans une revue
cea-01751739v1
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Activation of Astrocytes by CNTF Induces Metabolic Plasticity and Increases Resistance to Metabolic Insults
Carole Escartin
,
Karin Pierre
,
Angélique Colin
,
Emmanuel Brouillet
,
Thierry Delzescaux
,
et al.
Article dans une revue
cea-02290623v1
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The Neuroprotective Agent CNTF Decreases Neuronal Metabolites in the Rat Striatum: An $in\ Vivo$ Multimodal Magnetic Resonance Imaging Study
Maria-Angeles Carrillo-de Sauvage
,
Julien Flament
,
Yann Bramoullé
,
Lucile Ben Haim
,
Martine Guillermier
,
et al.
Article dans une revue
cea-02168367v1
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The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin
Laurie Galvan
,
Laetitia Francelle
,
Marie-Claude Gaillard
,
Lucie de Longprez
,
Maria-Angeles Carrillo-de Sauvage
,
et al.
Article dans une revue
hal-02074093v1
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THY-Tau22 mouse model accumulates more tauopathy at late stage of the disease in response to microglia deactivation through TREM2 deficiency
Audrey Vautheny
,
Charlotte Duwat
,
Gwennaëlle Aurégan
,
Charlène Joséphine
,
Anne-Sophie Hérard
,
et al.
Article dans une revue
inserm-03366724v1
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Mitochondria in Huntington's disease
Maria Damiano
,
Laurie Galvan
,
Nicole Déglon
,
Emmanuel Brouillet
Article dans une revue
hal-00543005v1
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Extreme conservation of the poly-glutamine tract in huntingtin is related to neurodevelopmental functions: the “better” may become the “enemy of the good” in the course of evolution
Emmanuel Brouillet
Article dans une revue
hal-04312713v1
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Energy defects in Huntington's disease: Why “in vivo” evidence matters
Géraldine Liot
,
Julien Valette
,
Jérémy Pépin
,
Julien Flament
,
Emmanuel Brouillet
Article dans une revue
cea-01752431v1
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