Emmanuel GUEDON

Documents

Publications

	Comparison of partial least square, artificial neural network, and support vector regressions for real‐time monitoring of CHO cell culture processes using in situ near‐infrared spectroscopy Daniel Zavala-Ortiz , Aurélia Denner , Maria Aguilar-Uscanga , Annie Marc , Bruno Ebel Biotechnology and Bioengineering, 2022, 119 (2), pp.535-549. ⟨10.1002/bit.27997⟩ Article dans une revue hal-03844328v1
	A new perfusion mode of culture for WJ‐MSCs expansion in a stirred and online monitored bioreactor Caroline Sion , Dima Ghannoum , Bruno Ebel , Fanny Gallo , Natalia Isla Biotechnology and Bioengineering, 2021, 118 (11), pp.4453-4464. ⟨10.1002/bit.27914⟩ Article dans une revue hal-03505287v1
	Effects of microcarriers addition and mixing on WJ-MSC culture in bioreactors C. Sion , C. Loubière , M.K. Wlodarczyk-Biegun , N. Davoudi , C. Müller-Renno Biochemical Engineering Journal, 2020, 157, pp.107521. ⟨10.1016/j.bej.2020.107521⟩ Article dans une revue hal-02968768v1
	Interest of locally weighted regression to overcome nonlinear effects during in situ NIR monitoring of CHO cell culture parameters and antibody glycosylation Daniel Zavala‐ortiz , Bruno Ebel , Meng‐yao Li , Dulce Ma. Barradas‐dermitz , Patricia Hayward‐jones Biotechnology Progress, 2020, 36 (e2924), pp.1-10. ⟨10.1002/btpr.2924⟩ Article dans une revue hal-02333228v1
	Corynebacterium glutamicum , a natural overproducer of succinic acid? Amani Briki , Karim Kaboré , Eric Olmos , Sabine Bosselaar , Fabrice Blanchard Engineering in Life Sciences, 2020, 20 (5-6), pp.205-215. ⟨10.1002/elsc.201900141⟩ Article dans une revue hal-02968827v1
	In situ cell differentiation monitoring of Catharanthus roseus suspension culture processes by NIR spectroscopy Daniel Zavala-Ortiz , Bruno Ebel , Emmanuel Guedon , Annie Marc , Dulce Barradas-Dermitz Bioprocess and Biosystems Engineering, 2020, 43, pp.747-752. ⟨10.1007/s00449-019-02255-x⟩ Article dans une revue hal-02366817v1
	Fermentation of cellulose pyrolysis oil by a Clostridial bacterium Felipe Buendia , Charles Greenhalf , Chiara Barbiero , Emmanuel Guedon , Cedric Briens Biomass and Bioenergy, 2020, 143, pp.105884. ⟨10.1016/j.biombioe.2020.105884⟩ Article dans une revue hal-04518916v1
	Support Vector and Locally Weighted regressions to monitor monoclonal antibody glycosylation during CHO cell culture processes, an enhanced alternative to Partial Least Squares regression Daniel Zavala-Ortiz , Bruno Ebel , Mengyao Li , Dulce Ma. Barradas‐dermitz , Patricia Hayward-Jones Biochemical Engineering Journal, 2020, 154, pp.107457. ⟨10.1016/j.bej.2019.107457⟩ Article dans une revue hal-02376535v1
	Dimensional analysis and CFD simulations of microcarrier ‘just-suspended’ state in mesenchymal stromal cells bioreactors Angélique Delafosse , Céline Loubière , Emmanuel Guedon , I. Chevalot , Dominique Toye Chemical Engineering Science, 2019, 203, pp.464-474. ⟨10.1016/j.ces.2019.04.001⟩ Article dans une revue hal-02151663v1
	Control of IgG glycosylation by in situ and real-time estimation of specific growth rate of CHO cells cultured in bioreactor Meng-Yao Li , Bruno Ebel , Fabrice Blanchard , Cedric Paris , Emmanuel Guedon Biotechnology and Bioengineering, 2019, 116, pp.985-993. ⟨10.1002/bit.26914⟩ Article dans une revue hal-01980640v1
	Optimization of the Impeller Design for Mesenchymal Stem Cell Culture on Microcarriers in Bioreactors Céline Loubière , Angélique Delafosse , Emmanuel Guedon , Dominique Toye , Isabelle Chevalot Chemical Engineering and Technology, 2019, 42 (8), pp.1702-1708. ⟨10.1002/ceat.201900105⟩ Article dans une revue hal-02151665v1
	Hydrothermal conversion of wood, organosolv and chlorite pulps Felipe Buendia-Kandia , Nicolas Brosse , Dominique Petitjean , Guillain Mauviel , Emmanuel Rondags Biomass Conversion and Biorefinery, 2019, 10 (1), pp.1. ⟨10.1007/s13399-019-00395-4⟩ Article dans une revue hal-02125963v1
	Impact of the type of microcarrier and agitation modes on the expansion performances of mesenchymal stem cells derived from umbilical cord Céline Loubière , Caroline Sion , Natalia de Isla , Loïc Reppel , Emmanuel Guedon Biotechnology Progress, 2019, 35 (6), pp.e2887. ⟨10.1002/btpr.2887⟩ Article dans une revue hal-02968491v1
	Parallel comparison of in situ Raman and NIR spectroscopies to simultaneously measure multiple variables toward real-time monitoring of CHO cell bioreactor cultures Mengyao Li , Bruno Ebel , Fabien Chauchard , Emmanuel Guedon , Annie Marc Biochemical Engineering Journal, 2018, 137, pp.205 - 213. ⟨10.1016/j.bej.2018.06.005⟩ Article dans une revue hal-01921094v1
	Light-sensitive dextran-covered PNBA nanoparticles as triggered drug delivery systems: Formulation, characteristics and cytotoxicity Meriem El Founi , Soliman Mehawed Abdellatif Soliman , Régis Vanderesse , Samir Acherar , Emmanuel Guedon Journal of Colloid and Interface Science, 2018, 514, pp.289 - 298. ⟨10.1016/j.jcis.2017.12.036⟩ Article dans une revue hal-01924074v1
	Diauxic growth of Clostridium acetobutylicum ATCC 824 when grown on mixtures of glucose and cellobiose Felipe Buendia-Kandia , Emmanuel Rondags , Xavier Framboisier , Guillain Mauviel , Anthony Dufour AMB Express, 2018, 8 (1), pp.9. ⟨10.1186/s13568-018-0615-2⟩ Article dans une revue hal-01797977v1
	Study and modeling of fluctuating dissolved oxygen concentration impact on Corynebacterium glutamicum growth in a scale-down bioreactor Abdoul Karim Kaboré , Stéphane Delaunay , Fabrice Blanchard , Emmanuel Guedon , Michel Fick Process Biochemistry, 2018, ⟨10.1016/j.procbio.2018.10.016⟩ Article dans une revue hal-01924081v1
	Real-time monitoring of antibody glycosylation site occupancy by in situ Raman spectroscopy during bioreactor CHO cell cultures Meng-Yao Li , Bruno Ebel , Cédric Paris , Fabien Chauchard , Emmanuel Guedon Biotechnology Progress, 2018, 34 (2), pp.486 - 493. ⟨10.1002/btpr.2604⟩ Article dans une revue hal-01921118v1
	Foreword Advances in “Stem Cell Bioengineering” Emmanuel Guedon Process Biochemistry, 2017, 59, pp.229 - 230. ⟨10.1016/j.procbio.2017.07.023⟩ Article dans une revue hal-01924087v1
	Decomposition of cellulose in hot-compressed water: detailed analysis of the products and effect of operating conditions Felipe Buendia-Kandia , Guillain Mauviel , Emmanuel Guedon , Emmanuel Rondags , Dominique Petitjean Energy & Fuels, 2017, ⟨10.1021/acs.energyfuels.7b02994⟩ Article dans une revue hal-01651273v1
	Revisiting MSC expansion from critical quality attributes to critical culture process parameters Céline Martin , Eric Olmos , Marie-Laure Collignon , Natalia de Isla , Fabrice Blanchard Process Biochemistry, 2017, 59, pp.231 - 243. ⟨10.1016/j.procbio.2016.04.017⟩ Article dans une revue hal-01921144v1
	3D in vitro co-culture models based on normal cells and tumor spheroids formed by cyclic RGD-peptide induced cell self-assembly Roman Akasov , Anastasia Gileva , Daria Zaytseva-Zotova , Sergey Burov , Isabelle Chevalot Biotechnology Letters, 2017, 39 (1), pp.45 - 53. ⟨10.1007/s10529-016-2218-9⟩ Article dans une revue hal-01921238v1
	Aerobiosis–anaerobiosis transition has a significant impact on organic acid production by Corynebacterium glutamicum Abdoul-Karim Kaboré , Eric Olmos , Michel Fick , Fabrice Blanchard , Emmanuel Guedon Process Biochemistry, 2017, 52, pp.10 - 21. ⟨10.1016/j.procbio.2016.10.007⟩ Article dans une revue hal-01924060v1
	A dual near-infrared and dielectric spectroscopies strategy to monitor populations of Chinese hamster ovary cells in bioreactor Franck Courtès , Bruno Ebel , Emmanuel Guedon , Annie Marc Biotechnology Letters, 2016, 38 (5), pp.745 - 750. ⟨10.1007/s10529-016-2036-0⟩ Article dans une revue hal-01921187v1
	Impact of gas-liquid mass transfer on organic acids production by Corynebacterium glutamicum in unbaffled shake flasks Abdoul Karim Kabore , Eric Olmos , Fabrice Blanchard , Michel Fick , Stéphane Delaunay Biochemical Engineering Journal, 2015, 101, pp.237-247. ⟨10.1016/j.bej.2015.06.003⟩ Article dans une revue hal-01266260v1
	Liposomal nanodelivery systems using soy and marine lecithin to encapsulate food biopreservative nisin Muhammad Imran , Anne-Marie Revol-Junelles , Cedric Paris , Emmanuel Guedon , Michel Linder LWT - Food Science and Technology, 2015, 62 (1, 1), pp.341-349. ⟨10.1016/j.lwt.2014.12.046⟩ Article dans une revue hal-01267001v1
	Lactate production as representative of the fermentation potential of Corynebacterium glutamicum 2262 in a one-step process Hoang Bao Truc Khuat , Abdoul Karim Kabore , Eric Olmos , Michel Fick , Joseph Boudrant Bioscience, Biotechnology and Biochemistry, 2014, 78 (2), pp.343-349. ⟨10.1080/09168451.2014.878219⟩ Article dans une revue hal-01276064v1
	Investigation of Growth Conditions for the Expansion of Porcine Mesenchymal Stem Cells on Microcarriers in Stirred Cultures Caroline Ferrari , Eric Olmos , Frederique Balandras , Nguyen Tran , Isabelle Chevalot Applied Biochemistry and Biotechnology, 2014, 172 (2), pp.1004-1017. ⟨10.1007/s12010-013-0586-3⟩ Article dans une revue hal-01276641v1
	Towards a Tissue-Engineered Ligament: Design and Preliminary Evaluation of a Dedicated Multi-Chamber Tension-Torsion Bioreactor Cédric Laurent , Cédryck Vaquette , Céline Martin , Emmanuel Guedon , Xiude Wu Processes, 2014, 2 (1), pp.167. ⟨10.3390/pr2010167⟩ Article dans une revue hal-01424974v1
	Biodegradation of phenanthrene by Pseudomonas putida and a bacterial consortium in the presence and in the absence of a surfactant Tatiana Pantsyrnaya , Stéphane Delaunay , Jean-Louis Goergen , Emmanuel Guedon , Cedric Paris Indian Journal of Microbiology, 2012, 52 (3), pp.420-426. ⟨10.1007/s12088-012-0265-z⟩ Article dans une revue hal-00777647v1
	Limiting Cell Aggregation During Mesenchymal Stem Cell Expansion on Microcarriers Caroline Ferrari , Frederique Balandras , Emmanuel Guedon , Eric Olmos , Isabelle Chevalot Biotechnology Progress, 2012, 28 (3), pp.780-787. ⟨10.1002/btpr.1527⟩ Article dans une revue hal-00777492v1
	Effect of surfactant pluronic F-68 on CHO cell growth, metabolism, production, and glycosylation of human recombinant IFN-γ in mild operating conditions M.F. Clincke , E. Guedon , F.T. Yen , V. Ogier , O. Roitel Biotechnology Progress, 2011, 27 ((1)), pp. 181-190. ⟨10.1002/btpr.503⟩ Article dans une revue hal-00606341v1
	Effect of surfactants, dispersion and temperature on solubility and biodegradation of phenanthrene in aqueous media. T. Pantsyrnaya , Fabian Blanchard , S. Delaunay , J.L. Goergen , E. Guedon Chemosphere, 2011, 83 ((1)), pp. 29-33. ⟨10.1016/j.chemosphere.2011.01.024⟩ Article dans une revue hal-00604685v1
	Effect of surfactants, dispersion and temperature on solubility and biodegradation of phenanthrene in aqueous media T. Pantsyrnaya , Fabian Blanchard , S. Delaunay , J.L. Goergen , E. Guédon Chemosphere, 2011, 83 (1), pp.29-33. ⟨10.1016/j.chemosphere.2011.01.024⟩ Article dans une revue hal-03060481v1
	Preliminary investigation of naringenin hydroxylation with recombinant E. coli expressing plant flavonoid hydroxylation gene Ilef Limen Ben Amor , Nidhal Salem , Emmanuel Guedon , Jean-Marc Engasser , Leila Chekir-Ghedira Natural Product Communications , 2010, 5 (5), pp.777-782. ⟨10.1177/1934578X1000500520⟩ Article dans une revue hal-00799073v1
	Biotransformation of Naringenin to Eriodictyol by Saccharomyces cerevisiea Functionally Expressing Flavonoid 3 ' Hydroxylase Ilef Limen Ben Amor , Alain Hehn , Emmanuel Guedon , Kamel Ghedira , Jean-Marc Engasser Natural Product Communications , 2010, 5 (12), pp.1893-1898. ⟨10.1177/1934578X1000501211⟩ Article dans une revue hal-00799067v1
	Kinetic characterization of vero cell metabolism in a serum-free batch culture process E. Petiot , E. Guedon , Fabian Blanchard , C. Gény , H. Pinton Biotechnology and Bioengineering, 2010, 107 ((1)), pp. 143-153. ⟨10.1002/bit.22783⟩ Article dans une revue hal-00611352v1
	OdhI dephosphorylation kinetics during different glutamate production processes involving Corynebacterium glutamicum Kenza-Amel Boulahya, , Emmanuel Guedon , Stéphane Delaunay , Christian Schultz , Joseph Boudrant European Journal of Applied Microbiology and Biotechnology, 2010, 87 (5), pp.1867-1874. ⟨10.1007/s00253-010-2599-y⟩ Article dans une revue hal-00799151v1
	Investigation of biological activity of polar extracts isolated from Phlomis crinita Cav ssp. mauritanica Munby I. Limem , I. Skandrani , J. Boubaker , M. Ben Sgaier , A. Neffati Drug and Chemical Toxicology, 2009, 32 (1), pp.38-46 Article dans une revue hal-00508044v1
	Production of phenylpropanoid compounds by recombinant microorganisms expressing plant-specific biosynthesis genes I. Limem , E. Guedon , A. Hehn , F. Bourgaud , L. Chekir Ghedira Process Biochemistry, 2008, 43 (5), pp.463-479. ⟨10.1016/j.procbio.2008.02.001⟩ Article dans une revue hal-00379981v1
	Influence of intracellular nucleotide and nucleotide sugar contents on recombinant interferon-gamma; glycosylation during batch and fed-batch cultures of CHO cells N. Kochanowski , Fabian Blanchard , R. Cacan , F. Chirat , A. Marc Biotechnology and Bioengineering, 2008, 100 (4), pp.721-733. ⟨10.1002/bit.21816⟩ Article dans une revue hal-00379732v1
	Décontamination de sols pollués par les hydrocarbures aromatiques polycycliques par biodégradation en présence de substrats organiques supplémentaires N. Simeon , G. Mercier , J.F. Blais , Stéphanie Ouvrard , A. Cebron Revue du Génie et de la Science de l'Environnement, 2008, 7 (5), pp.467-479. ⟨10.1139/S08-027⟩ Article dans une revue hal-00380365v1
	Mathematical modeling of L-glutamic acid production T. Nizhegorodova , E. Guseva , N. Menshutina , J. Boudrant , J.L. Goergen Izvestiya Vuzov. Seria Himiya i himicheskaya tehnologiya, 2007, 50, pp.93-98 Article dans une revue hal-00278429v1
	Cell envelope fluidity modification for an affective glutamate excretion in Corynebacterium glutamicum 2262 D. Bokas , D. Uy , F. Grattepanche , G. Duportail , E. Guedon Applied Microbiology and Biotechnology, 2007, 76, pp.773-781 Article dans une revue hal-00171988v1
	Cell envelope fluidity modification for an effective glutamate excretion in Corynebacterium glutamicum 2262 D. Bokas , D. Uy , F. Grattepanche , G. Duportail , Emmanuel Guedon Applied Microbiology and Biotechnology, 2007, 76 (4), pp.773-781. ⟨10.1007/s00253-007-1046-1⟩ Article dans une revue hal-00277816v1
	Intracellular nucleotide and nucleotide sugar contents of cultured CHO cells determined by a fast, sensitive, and high-resolution ion-pair RP-HPLC N. Kochanowski , Fabian Blanchard , R. Cacan , F. Chirat , E. Guedon Analytical Biochemistry, 2006, 348 (2), pp.243-251. ⟨10.1016/j.ab.2005.10.027⟩ Article dans une revue hal-00077315v1
	Improvement of Cellulolytic Properties of Clostridium cellulolyticum by Metabolic Engineering Emmanuel Guedon , Mickaël Desvaux , Henri Petitdemange Applied and Environmental Microbiology, 2002, 68 (1), pp.53 - 58. ⟨10.1128/AEM.68.1.53-58.2002⟩ Article dans une revue hal-02910792v1
	Both pH and carbon flux influence the level of rubredoxin in Clostridium butyricum Emmanuel Guedon , Philippe Gerard , Bruno Charpentier , Christiane Branlant , Henri Petitdemange Current Microbiology, 2001, 43 (6), pp.434-439. ⟨10.1007/s002840010334⟩ Article dans une revue hal-01600080v1
	Carbon Flux Distribution and Kinetics of Cellulose Fermentation in Steady-State Continuous Cultures of Clostridium cellulolyticum on a Chemically Defined Medium Mickaël Desvaux , Emmanuel Guedon , Henri Petitdemange Journal of Bacteriology, 2001, 183 (1), pp.119-130. ⟨10.1128/JB.183.1.119-130.2001⟩ Article dans une revue hal-02910799v1
	Metabolic flux in cellulose batch and cellulose-fed continuous cultures of Clostridium cellulolyticum in response to acidic environment Mickaël Desvaux , Emmanuel Guedon , Henri Petitdemange Microbiology, 2001, 147 (6), pp.1461-1471. ⟨10.1099/00221287-147-6-1461⟩ Article dans une revue hal-02910800v1
	Réseau de régulation de la transcription des gènes du système protéolytique de Lactococcus lactis E. Guedon , C. Martin , F.X. Gobert , S.D. Ehrlich , P. Renault Lait, 2001, 81 (1-2), pp.65-74 Article dans une revue hal-02674703v1
	Kinetics and Metabolism of Cellulose Degradation at High Substrate Concentrations in Steady-State Continuous Cultures of Clostridium cellulolyticum on a Chemically Defined Medium Mickaël Desvaux , Emmanuel Guedon , Henri Petitdemange Applied and Environmental Microbiology, 2001, 67 (9), pp.3837 - 3845. ⟨10.1128/AEM.67.9.3837-3845.2001⟩ Article dans une revue hal-02910803v1
	Kinetic Analysis of Clostridium cellulolyticum Carbohydrate Metabolism: Importance of Glucose 1-Phosphate and Glucose 6-Phosphate Branch Points for Distribution of Carbon Fluxes Inside and Outside Cells as Revealed by Steady-State Continuous Culture Emmanuel Guedon , Mickaël Desvaux , Henri Petitdemange Journal of Bacteriology, 2000, 182 (7), pp.2010-2017. ⟨10.1128/JB.182.7.2010-2017.2000⟩ Article dans une revue hal-02910812v1
	Relationships Between Cellobiose Catabolism, Enzyme Levels, and Metabolic Intermediates in Clostridium cellulolyticum Grown in a Synthetic Medium Emmanuel Guedon , Sophie Payot , M Desvaux , H. Petitdemange Inc. Biotechnol Bioeng, 2000, 67, pp.327 - 335 Article dans une revue hal-02910822v1
	Cellulose Catabolism by Clostridium cellulolyticum Growing in Batch Culture on Defined Medium Downloaded from Mickaël Desvaux , Emmanuel Guedon , Henri Petitdemange Applied and Environmental Microbiology, 2000, 66 (6), pp.2461 - 2470. ⟨10.1128/AEM.66.6.2461-2470.2000⟩ Article dans une revue hal-02910808v1
	Evaluation de la diversité de l'expression génétique chez les lactocoques : développement d'un outil et son application aux peptidases E. Guedon , P. Renault , S.D. Ehrlich , Christine C. Delorme Sciences des aliments = Food science : an international journal of food science and technology, 2000, 20 (1), pp.55-62 Article dans une revue hal-02684710v1
	The Extracellular Xylan Degradative System in Clostridium cellulolyticum Cultivated on Xylan: Evidence for Cell-Free Cellulosome Production O. Mohand-Oussaid , Sophie Payot , E. Guedon , Éric Gelhaye , A. Youyou Journal of Bacteriology, 1999, 181 (13) Article dans une revue hal-01787581v1
	Growth inhibition of Clostridium cellulolyticum by an inefficiently regulated carbon flow E. Guedon , Mickaël Desvaux , Sophie Payot , H. Petitdemange Microbiology, 1999, 145 (8), pp.1831 - 1838. ⟨10.1099/13500872-145-8-1831⟩ Article dans une revue hal-01787598v1
	Induction of lactate production associated with a decrease in NADH cell content enables growth resumption of Clostridium cellulolyticum in batch cultures on cellobiose Sophie Payot , Emmanuel Guedon , Éric Gelhaye , Henri Petitdemange Research in Microbiology, 1999, 150 (7), pp.465 - 473. ⟨10.1016/S0923-2508(99)00110-2⟩ Article dans une revue hal-01787587v1
	Carbon and Electron Flow in Clostridium cellulolyticum Grown in Chemostat Culture on Synthetic Medium Downloaded from Emmanuel Guedon , Sophie Payot , Mickaël Desvaux , H. Petitdemange Journal of Bacteriology, 1999, 181 (10), pp.3262 - 3269. ⟨10.1128/JB.181.10.3262-3269.1999⟩ Article dans une revue hal-02910828v1
	Effect of dilution rate, cellobiose and ammonium availabilities on Clostridium cellulolyticum sporulation Sophie Payot , Emmanuel Guedon , Mickaël Desvaux , Éric Gelhaye , E. Petitdemange Applied Microbiology and Biotechnology, 1999, 52 (5), pp.670-674. ⟨10.1007/s002530051577⟩ Article dans une revue hal-02910824v1
	Metabolism of cellobiose by Clostridium cellulolyticum growing in continuous culture: evidence for decreased NADH reoxidation as a factor limiting growth Sophie Payot , E. Guedon , C. Cailliez , Éric Gelhaye , H. Petitdemange Microbiology, 1998, 144 (2), pp.375 - 384. ⟨10.1099/00221287-144-2-375⟩ Article dans une revue hal-01787609v1
	Du génome à l'application P. Renault , S. Calero , Christine C. Delorme , S. Drouault , N. Goupil-Feuillerat Lait, 1998, 78, pp.39-52 Article dans une revue hal-02684934v1

	Enhanced method to monitor cell cultures by dielectric spectroscopy Daniel Zavala-Ortiz , Mengyao Li , Maria Aguilar-Uscanga , Javier Gomez-Rodrigues , Dulce Barradas-Dermitz 26th ESACT meeting " Cell culture technologies: bridging academia and industry to provide solutions for patients", BMC Proceedings, May 2019, Copenhague, Denmark Communication dans un congrès hal-02333492v1
	Chemometrics to monitor CHO cell cultures quality by in situ NIRS Daniel Zavala-Ortiz , Mengyao Li , Maria Aguilar-Uscanga , Javier Gomez-Rodrigues , Dulce Barradas-Dermitz 26th ESACT meeting " Cell culture technologies: bridging academia and industry to provide solutions for patients", BMC Proceedings, May 2019, Copenhague, Denmark Communication dans un congrès hal-02333483v1
	Cellulose valorization in biorefinery: integration of fast pyrolysis and fermentation for building blocks production Felipe Buendia , Charles Greenhalf , Franco Berruti , Cedric Briens , Emmanuel Guedon Pyroliq 2019: Pyrolysis and Liquefaction of Biomass and Wastes, Jun 2019, Cork, Ireland Communication dans un congrès hal-04518909v1
	In situ Raman spectroscopy as a promising PAT tool for monitoring of macro and micro-heterogeneity of monoclonal antibody glycosylation produced by CHO cells in bioreactors Mengyao Li , Bruno Ebel , Cédric Paris , Fabien Chauchard , Emmanuel Guedon 5th BioProScale Symposium: Innovative scale up and scale down for bioprocess intensification, Mar 2018, Berlin, Germany Communication dans un congrès hal-02333510v1
	In situ Raman spectroscopy monitoring of macro and micro-heterogeneity of monoclonal antibody glycosylation produced by CHO cells in bioreactors Mengyao Li , Bruno Ebel , Cédric Paris , Fabien Chauchard , Emmanuel Guedon 5th BioProScale Symposium: Innovative scale up and scale down for bioprocess intensification, Mar 2018, Berlin, Germany Communication dans un congrès hal-01922509v1
	Real-time analysis of antibody glycosylation using in-line Raman spectroscopy in cell culture Mengyao Li , Bruno Ebel , Cédric Paris , Fabien Chauchard , Emmanuel Guedon 3rd Conference on Process Optimization and Safety in Industry 4.0, Sep 2018, Paris, France Communication dans un congrès hal-01922497v1
	Online and real-time control of CHO cell specific growth rate throughout cultures in bioreactor Mengyao Li , Bruno Ebel , Frantz Fournier , Emmanuel Guedon , Annie Marc 25th ESACT meeting "Cell technologies for innovative therapies", BMC Proceedings 2017, 12 (Suppl 1):3-P134, May 2017, Lausanne, Switzerland Communication dans un congrès hal-01922275v1
	Nanoparticules à coeur poly(acrylate d'o-nitrobenzyle) et couronne polysaccharide : vers un traitement anticancéreux photo-activable Meriem El Founi , Soliman Mehawed Abdellatif Soliman , Emmanuel Guedon , Isabelle Chevalot , Vanderesse Régis GFP 2017, Nov 2017, Paris, France Communication dans un congrès hal-03239706v1
	PNBA-based photosensitive nanoparticles: a novel devices for controlled drug delivery Meriem El Founi , Soliman Mehawed Abdellatif Soliman , Régis Vanderesse , Samir Acherar , Emmanuel Guedon 91st ACS Colloid and Surface Science Symposium, Jul 2017, New York, United States Communication dans un congrès hal-03239576v1
	Systèmes nanoparticulaires d'administration de médicaments à base de poly(acrylate d'o-nitrobenzyle) et à libération photodéclenchée Meriem El Founi , Soliman Mehawed Abdellatif Soliman , Emmanuel Guedon , Isabelle Chevalot , Vanderesse Régis 15e Journée Scientifique du GFP section Grand-Est, Jun 2017, strasbourg, France Communication dans un congrès hal-03239657v1
	Serum-free media for mesenchymal stem cells expansion on microcarriers Céline Martin , Alexandre Piccini , Isabelle Chevalot , Eric Olmos , Emmanuel Guedon 24th European Society for Animal Cell Technology (ESACT) Meeting: C2P2: Cells, Culture, Patients, Products, May 2015, Barcelone, Spain. ⟨10.1186/1753-6561-9-S9-P70⟩ Communication dans un congrès hal-01305688v1
	Real-time monitoring of the physiological state of CHO cells in bioreactor by using a dual spectroscopic strategy Franck Courtès , Bruno Ebel , Emmanuel Guedon , Annie Marc 24th European Society for Animal Cell Technology (ESACT) Meeting: C2P2: Cells, Culture, Patients, Products, May 2015, Barcelone, Spain. ⟨10.1186/1753-6561-9-S9-P48⟩ Communication dans un congrès hal-01305628v1
	Recent advances in the study of the hydrodynamics of bioreactors used for the culture of living cells Éric Olmos , Abdoul Karim Kabore , Céline Martin , Marie-Laure Collignon , Isabelle Chevalot 9th international symposium on CAtalysis in MUltiphase Reactors, Dec 2014, Lyon, France Communication dans un congrès hal-01922581v1
	Stress during cell culture processes J. Boudrant , N. Barbouche , N. Mehmood , E. Olmos , S. Delaunay 13th International Biotechnology Symposium and Exhibition, Biotechnology for the Sustainability of Human Society, Oct 2008, DALIAN, China Communication dans un congrès hal-00401153v1
	Contraintes hydrodynamiques et culture de cellules animales en réacteur : quel rôle pour le copolymère Pluronic-68 ? N. Barbouche , E. Guedon , A. Marc , E. Olmos Colloque de la fédération Gay-Lussac "La chimie du et pour le vivant", Dec 2008, RENNES, France Communication dans un congrès hal-00401130v1
	Réseau de régulation de la transcription des gènes du système protéolytique de Lactococcus lactis E. Guedon , C. Martin , F.X. Gobert , S.D. Ehrlich , P. Renault 10. Colloque du Club des Bactéries Lactiques, Apr 2000, Strasbourg, France Communication dans un congrès hal-02825666v1
	Etude de l'adaptation de Lactococcus lactis a l'environnement digestif : approche génétique Gerard Corthier , Sophie Gilbert , M.C. Muller , Christine C. Delorme , S. Drouault Rencontres des Microbiologistes de l'INRA, Apr 1999, Dourdan, France Communication dans un congrès hal-02771131v1
	Evaluation de la diversité de l'expression génétique chez les lactocoques : développement d'un outil et son application aux peptidases E. Guedon , P. Renault , S.D. Ehrlich , Christine C. Delorme 9. Colloque du Club des Bactéries Lactiques, Oct 1998, Bourg-en-Bresse, France Communication dans un congrès hal-02835362v1

	Suivi en-ligne de la qualité d’anticorps produits par cellules CHO par spectrométrie NIR in situ couplée à une régression à vecteurs de support Daniel Zavala-Ortiz , Bruno Ebel , Mengyao Li , Maria Aguilar-Uscanga , Javier Gomez-Rodrigues 17ème Congrès de la Société Française de Génie des Procédés, Oct 2019, Nantes, France Poster de conférence hal-02333525v1
	Interest of cell heterogeneity for the production of anticancer drugs vincristine and vinblastine by suspension cultures of Catharanthus roseus Daniel Zavala-Ortiz , Dulce Barradas-Dermitz , Bruno Ebel , Emmanuel Guedon , Annie Marc 40th National Meeting of the AMIDIQ, "Challenges of chemical engineering for national development", May 2019, Hualtuco, Mexico Poster de conférence hal-02333533v1
	Amélioration du suivi en temps réel de l’état physiologique de cellules CHO par spectroscopie diélectrique in situ et régression à vecteurs de support Daniel Zavala-Ortiz , Bruno Ebel , Mengyao Li , Maria Aguilar-Uscanga , Javier Gomez-Rodrigues 17ème Congrès de la Société Française de Génie des Procédés, Oct 2019, Nantes, France Poster de conférence hal-02333522v1
	Improvement of the production process of Taxus globosa S. cells by cellular synchronization for the subsequent production of the anti-cancer paclitaxel Daniel Zavala-Ortiz , Dulce Barradas-Dermitz , Bruno Ebel , Emmanuel Guedon , Annie Marc Congrès de l'AMIDIQ (Academia Mexicana de Investigation y Docencia en Ingeniera Quimica), San José des Cabo, Mexique, 1 - 4 mai 2018, May 2018, San José des Cabo, Mexico Poster de conférence hal-01922390v1
	Interest of NIR spectroscopy to perform rapid analysis of medium compounds of Taxus globosa plant cells cultivated in suspension Daniel Zavala-Ortiz , Bruno Ebel , Mengyao Li , Dulce Barradas-Dermitz , Maria Aguilar-Uscanga 12th European Symposium on Biochemical Engineering Sciences, Sep 2018, Lisbonne, Portugal Poster de conférence hal-01922399v1
	Interest of the Locally Weighted Regression to improve real-time monitoring of CHO and antibody quality by using in situ NIR spectroscopy Daniel Zavala-Ortiz , Bruno Ebel , Emmanuel Guedon , Annie Marc , Dulce Barradas-Dermitz 12th European Symposium on Biochemical Engineering Sciences, Sep 2018, Lisbonne, Portugal Poster de conférence hal-01922411v1
	Intérêt de l'estimation en temps réel de la vitesse spécifique de croissance pour le pilotage de cultures de cellules animales Mengyao Li , Bruno Ebel , Frantz Fournier , Emmanuel Guedon , Annie Marc 16ème Congrès de la Société Française de Génie des Procédés, Jul 2017, Nancy, France Poster de conférence hal-01922378v1
	Utilisation combinée de techniques spectroscopiques pour le suivi en ligne de l'état physiologique de cellules CHO cultivées en bioréacteur Franck Courtès , Bruno Ebel , Emmanuel Guedon , Annie Marc 21èmes journées du Groupe Français de Spectroscopies Vibrationnelles, Jun 2015, Reims, France Poster de conférence hal-01922324v1
	Ethanol production monitoring during Pichia Stipitis yeasts fermentation using on-line near-infrared spectroscopy Victor Corro , Patricia Hayward-Jones , Dulce Barradas-Dermitz , Anne Gschaedler , Bruno Ebel 3rd European Congress of Applied Biotechnology, Oct 2015, Nice, France Poster de conférence hal-01922340v1

	In situ infrared spectroscopy as a PAT tool of great promise for real-time monitoring of animal cell culture processes Mengyao Li , Bruno Ebel , Franck Courtès , Emmanuel Guedon , Annie Marc Journal of Analytical and Pharmaceutical Chemistry, 3, 2, 1065-70, 2016 Chapitre d'ouvrage hal-01922462v1
	Anaerobie production of organie acids and alcohols with Corynebacterium glutamicum Stéphane Delaunay , Abdoul Karim Kabore , Mickael Cregut , Huang Bao Truc Khuat , Emmanuel Guedon Carlos Barreiro. New trends in Corynebacterium glutamicum: beyond the amino acids, Nova Sciences Pub, 2015, 978-1-63483-280-9 Chapitre d'ouvrage hal-01962320v1
	Défis de la culture de cellules animales en bioréacteur Annie Marc , Emmanuel Guedon , Eric Olmos , Fabrice Blanchard , Isabelle Chevalot Culture de cellules animales, 3ème édition (eds. G. Barlovatz-Meimon, X. Ronot), pp. 61-70. Tec&Doc, Lavoisier, Paris, 2014 Chapitre d'ouvrage hal-01922265v1
	Procédés biotechnologiques pour la production de protéines recombinantes à usage thérapeutiques : vers une maîtrise de la glycosylation M.F. Clincke , Emmanuel Guedon , Jean-Louis Goergen Traité Bioprocédés, Techniques de l'Ingénieur, BIO 6 200 p. 1-19, 2011 Chapitre d'ouvrage hal-00822941v1

	Analyse du Métabolisme de Clostridium cellulolyticum. Importance des Débordements Cataboliques dans la Distribution du Flux du Carbone et des Électrons Emmanuel Guedon Biochimie, Biologie Moléculaire. Université Henri Poincaré - Nancy 1, 2000. Français. ⟨NNT : 2000NAN10121⟩ Thèse tel-01746476v1

Emmanuel GUEDON

Publications

Comparison of partial least square, artificial neural network, and support vector regressions for real‐time monitoring of CHO cell culture processes using in situ near‐infrared spectroscopy

A new perfusion mode of culture for WJ‐MSCs expansion in a stirred and online monitored bioreactor

Effects of microcarriers addition and mixing on WJ-MSC culture in bioreactors

Interest of locally weighted regression to overcome nonlinear effects during in situ NIR monitoring of CHO cell culture parameters and antibody glycosylation

Corynebacterium glutamicum , a natural overproducer of succinic acid?

In situ cell differentiation monitoring of Catharanthus roseus suspension culture processes by NIR spectroscopy

Fermentation of cellulose pyrolysis oil by a Clostridial bacterium

Support Vector and Locally Weighted regressions to monitor monoclonal antibody glycosylation during CHO cell culture processes, an enhanced alternative to Partial Least Squares regression

Dimensional analysis and CFD simulations of microcarrier ‘just-suspended’ state in mesenchymal stromal cells bioreactors

Control of IgG glycosylation by in situ and real-time estimation of specific growth rate of CHO cells cultured in bioreactor

Optimization of the Impeller Design for Mesenchymal Stem Cell Culture on Microcarriers in Bioreactors

Hydrothermal conversion of wood, organosolv and chlorite pulps

Impact of the type of microcarrier and agitation modes on the expansion performances of mesenchymal stem cells derived from umbilical cord

Parallel comparison of in situ Raman and NIR spectroscopies to simultaneously measure multiple variables toward real-time monitoring of CHO cell bioreactor cultures

Light-sensitive dextran-covered PNBA nanoparticles as triggered drug delivery systems: Formulation, characteristics and cytotoxicity

Diauxic growth of Clostridium acetobutylicum ATCC 824 when grown on mixtures of glucose and cellobiose

Study and modeling of fluctuating dissolved oxygen concentration impact on Corynebacterium glutamicum growth in a scale-down bioreactor

Real-time monitoring of antibody glycosylation site occupancy by in situ Raman spectroscopy during bioreactor CHO cell cultures

Foreword Advances in “Stem Cell Bioengineering”

Decomposition of cellulose in hot-compressed water: detailed analysis of the products and effect of operating conditions

Revisiting MSC expansion from critical quality attributes to critical culture process parameters

3D in vitro co-culture models based on normal cells and tumor spheroids formed by cyclic RGD-peptide induced cell self-assembly

Aerobiosis–anaerobiosis transition has a significant impact on organic acid production by Corynebacterium glutamicum

A dual near-infrared and dielectric spectroscopies strategy to monitor populations of Chinese hamster ovary cells in bioreactor

Impact of gas-liquid mass transfer on organic acids production by Corynebacterium glutamicum in unbaffled shake flasks

Liposomal nanodelivery systems using soy and marine lecithin to encapsulate food biopreservative nisin

Lactate production as representative of the fermentation potential of Corynebacterium glutamicum 2262 in a one-step process

Investigation of Growth Conditions for the Expansion of Porcine Mesenchymal Stem Cells on Microcarriers in Stirred Cultures

Towards a Tissue-Engineered Ligament: Design and Preliminary Evaluation of a Dedicated Multi-Chamber Tension-Torsion Bioreactor

Biodegradation of phenanthrene by Pseudomonas putida and a bacterial consortium in the presence and in the absence of a surfactant

Limiting Cell Aggregation During Mesenchymal Stem Cell Expansion on Microcarriers

Effect of surfactant pluronic F-68 on CHO cell growth, metabolism, production, and glycosylation of human recombinant IFN-γ in mild operating conditions

Effect of surfactants, dispersion and temperature on solubility and biodegradation of phenanthrene in aqueous media.

Effect of surfactants, dispersion and temperature on solubility and biodegradation of phenanthrene in aqueous media

Preliminary investigation of naringenin hydroxylation with recombinant E. coli expressing plant flavonoid hydroxylation gene

Biotransformation of Naringenin to Eriodictyol by Saccharomyces cerevisiea Functionally Expressing Flavonoid 3 ' Hydroxylase

Kinetic characterization of vero cell metabolism in a serum-free batch culture process

OdhI dephosphorylation kinetics during different glutamate production processes involving Corynebacterium glutamicum

Investigation of biological activity of polar extracts isolated from Phlomis crinita Cav ssp. mauritanica Munby

Production of phenylpropanoid compounds by recombinant microorganisms expressing plant-specific biosynthesis genes

Influence of intracellular nucleotide and nucleotide sugar contents on recombinant interferon-gamma; glycosylation during batch and fed-batch cultures of CHO cells

Décontamination de sols pollués par les hydrocarbures aromatiques polycycliques par biodégradation en présence de substrats organiques supplémentaires

Mathematical modeling of L-glutamic acid production

Cell envelope fluidity modification for an affective glutamate excretion in Corynebacterium glutamicum 2262

Cell envelope fluidity modification for an effective glutamate excretion in Corynebacterium glutamicum 2262

Intracellular nucleotide and nucleotide sugar contents of cultured CHO cells determined by a fast, sensitive, and high-resolution ion-pair RP-HPLC

Improvement of Cellulolytic Properties of Clostridium cellulolyticum by Metabolic Engineering

Both pH and carbon flux influence the level of rubredoxin in Clostridium butyricum

Carbon Flux Distribution and Kinetics of Cellulose Fermentation in Steady-State Continuous Cultures of Clostridium cellulolyticum on a Chemically Defined Medium

Metabolic flux in cellulose batch and cellulose-fed continuous cultures of Clostridium cellulolyticum in response to acidic environment

Réseau de régulation de la transcription des gènes du système protéolytique de Lactococcus lactis

Kinetics and Metabolism of Cellulose Degradation at High Substrate Concentrations in Steady-State Continuous Cultures of Clostridium cellulolyticum on a Chemically Defined Medium

Kinetic Analysis of Clostridium cellulolyticum Carbohydrate Metabolism: Importance of Glucose 1-Phosphate and Glucose 6-Phosphate Branch Points for Distribution of Carbon Fluxes Inside and Outside Cells as Revealed by Steady-State Continuous Culture

Relationships Between Cellobiose Catabolism, Enzyme Levels, and Metabolic Intermediates in Clostridium cellulolyticum Grown in a Synthetic Medium

Cellulose Catabolism by Clostridium cellulolyticum Growing in Batch Culture on Defined Medium Downloaded from

Evaluation de la diversité de l'expression génétique chez les lactocoques : développement d'un outil et son application aux peptidases

The Extracellular Xylan Degradative System in Clostridium cellulolyticum Cultivated on Xylan: Evidence for Cell-Free Cellulosome Production

Growth inhibition of Clostridium cellulolyticum by an inefficiently regulated carbon flow

Induction of lactate production associated with a decrease in NADH cell content enables growth resumption of Clostridium cellulolyticum in batch cultures on cellobiose

Carbon and Electron Flow in Clostridium cellulolyticum Grown in Chemostat Culture on Synthetic Medium Downloaded from

Effect of dilution rate, cellobiose and ammonium availabilities on Clostridium cellulolyticum sporulation

Metabolism of cellobiose by Clostridium cellulolyticum growing in continuous culture: evidence for decreased NADH reoxidation as a factor limiting growth

Du génome à l'application

Enhanced method to monitor cell cultures by dielectric spectroscopy

Chemometrics to monitor CHO cell cultures quality by in situ NIRS

Cellulose valorization in biorefinery: integration of fast pyrolysis and fermentation for building blocks production

In situ Raman spectroscopy as a promising PAT tool for monitoring of macro and micro-heterogeneity of monoclonal antibody glycosylation produced by CHO cells in bioreactors

In situ Raman spectroscopy monitoring of macro and micro-heterogeneity of monoclonal antibody glycosylation produced by CHO cells in bioreactors

Real-time analysis of antibody glycosylation using in-line Raman spectroscopy in cell culture

Online and real-time control of CHO cell specific growth rate throughout cultures in bioreactor

Nanoparticules à coeur poly(acrylate d'o-nitrobenzyle) et couronne polysaccharide : vers un traitement anticancéreux photo-activable

PNBA-based photosensitive nanoparticles: a novel devices for controlled drug delivery

Systèmes nanoparticulaires d'administration de médicaments à base de poly(acrylate d'o-nitrobenzyle) et à libération photodéclenchée

Serum-free media for mesenchymal stem cells expansion on microcarriers

Real-time monitoring of the physiological state of CHO cells in bioreactor by using a dual spectroscopic strategy

Recent advances in the study of the hydrodynamics of bioreactors used for the culture of living cells

Stress during cell culture processes

Contraintes hydrodynamiques et culture de cellules animales en réacteur : quel rôle pour le copolymère Pluronic-68 ?