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Number of documents

91

CV Emmanuel GUEDON, Directeur de Recherche CNRS, LRGP UMR 7274


Journal articles63 documents

  • Buendia-Kandia Felipe, Charles Greenhalf, Chiara Barbiero, E. Guédon, Cedric Briens, et al.. Fermentation of cellulose pyrolysis oil by a Clostridial bacterium. Biomass and Bioenergy, Elsevier, 2020, 143, pp.105884. ⟨10.1016/j.biombioe.2020.105884⟩. ⟨hal-03094948⟩
  • Daniel Zavala-Ortiz, Bruno Ebel, Mengyao Li, Dulce Ma. Barradas‐dermitz, Patricia Hayward-Jones, et al.. Support Vector and Locally Weighted regressions to monitor monoclonal antibody glycosylation during CHO cell culture processes, an enhanced alternative to Partial Least Squares regression. Biochemical Engineering Journal, Elsevier, 2020, 154, pp.107457. ⟨10.1016/j.bej.2019.107457⟩. ⟨hal-02376535⟩
  • Daniel Zavala-Ortiz, Bruno Ebel, Emmanuel Guedon, Annie Marc, Dulce Barradas-Dermitz, et al.. In situ cell differentiation monitoring of Catharanthus roseus suspension culture processes by NIR spectroscopy. Bioprocess and Biosystems Engineering, Springer Verlag, 2020, 43, pp.747-752. ⟨10.1007/s00449-019-02255-x⟩. ⟨hal-02366817⟩
  • C. Sion, C. Loubière, M.K. Wlodarczyk-Biegun, N. Davoudi, C. Müller-Renno, et al.. Effects of microcarriers addition and mixing on WJ-MSC culture in bioreactors. Biochemical Engineering Journal, Elsevier, 2020, 157, pp.107521. ⟨10.1016/j.bej.2020.107521⟩. ⟨hal-02968768⟩
  • Daniel Zavala‐ortiz, Bruno Ebel, Meng‐yao Li, Dulce Ma. Barradas‐dermitz, Patricia Hayward‐jones, et al.. Interest of locally weighted regression to overcome nonlinear effects during in situ NIR monitoring of CHO cell culture parameters and antibody glycosylation. Biotechnology Progress, Wiley, 2020, 36 (e2924), pp.1-10. ⟨10.1002/btpr.2924⟩. ⟨hal-02333228⟩
  • Amani Briki, Karim Kaboré, Eric Olmos, Sabine Bosselaar, Fabrice Blanchard, et al.. Corynebacterium glutamicum , a natural overproducer of succinic acid?. Engineering in Life Sciences, Wiley-VCH Verlag, 2020, 20 (5-6), pp.205-215. ⟨10.1002/elsc.201900141⟩. ⟨hal-02968827⟩
  • Felipe Buendia-Kandia, Nicolas Brosse, Dominique Petitjean, Guillain Mauviel, Emmanuel Rondags, et al.. Hydrothermal conversion of wood, organosolv and chlorite pulps. Biomass Conversion and Biorefinery, Springer, 2019, 10 (1), pp.1. ⟨10.1007/s13399-019-00395-4⟩. ⟨hal-02125963⟩
  • Céline Loubière, Angélique Delafosse, Emmanuel Guedon, Dominique Toye, Isabelle Chevalot, et al.. Optimization of the Impeller Design for Mesenchymal Stem Cell Culture on Microcarriers in Bioreactors. Chemical Engineering and Technology, Wiley-VCH Verlag, 2019, 42 (8), pp.1702-1708. ⟨10.1002/ceat.201900105⟩. ⟨hal-02151665⟩
  • Céline Loubière, Caroline Sion, Natalia de Isla, Loïc Reppel, Emmanuel Guedon, et al.. Impact of the type of microcarrier and agitation modes on the expansion performances of mesenchymal stem cells derived from umbilical cord. Biotechnology Progress, Wiley, 2019, 35 (6), ⟨10.1002/btpr.2887⟩. ⟨hal-02968491⟩
  • Meng-Yao Li, Bruno Ebel, Fabrice Blanchard, Cedric Paris, Emmanuel Guedon, et al.. Control of IgG glycosylation by in situ and real-time estimation of specific growth rate of CHO cells cultured in bioreactor. Biotechnology and Bioengineering, Wiley, 2019, 116, pp.985-993. ⟨10.1002/bit.26914⟩. ⟨hal-01980640⟩
  • Angélique Delafosse, Céline Loubière, Emmanuel Guedon, I. Chevalot, Dominique Toye, et al.. Dimensional analysis and CFD simulations of microcarrier ‘just-suspended’ state in mesenchymal stromal cells bioreactors. Chemical Engineering Science, Elsevier, 2019, 203, pp.464-474. ⟨10.1016/j.ces.2019.04.001⟩. ⟨hal-02151663⟩
  • Felipe Buendia-Kandia, Emmanuel Rondags, Xavier Framboisier, Guillain Mauviel, Anthony Dufour, et al.. Diauxic growth of Clostridium acetobutylicum ATCC 824 when grown on mixtures of glucose and cellobiose. AMB Express, Springer Nature, 2018, 8 (1), pp.9. ⟨10.1186/s13568-018-0615-2⟩. ⟨hal-01797977⟩
  • Meriem El Founi, Soliman Mehawed Abdellatif Soliman, Régis Vanderesse, Samir Acherar, Emmanuel Guedon, et al.. Light-sensitive dextran-covered PNBA nanoparticles as triggered drug delivery systems: Formulation, characteristics and cytotoxicity. Journal of Colloid and Interface Science, Elsevier, 2018, 514, pp.289 - 298. ⟨10.1016/j.jcis.2017.12.036⟩. ⟨hal-01924074⟩
  • Meng-Yao Li, Bruno Ebel, Cédric Paris, Fabien Chauchard, Emmanuel Guedon, et al.. Real-time monitoring of antibody glycosylation site occupancy by in situ Raman spectroscopy during bioreactor CHO cell cultures. Biotechnology Progress, Wiley, 2018, 34 (2), pp.486 - 493. ⟨10.1002/btpr.2604⟩. ⟨hal-01921118⟩
  • Mengyao Li, Bruno Ebel, Fabien Chauchard, Emmanuel Guedon, Annie Marc. Parallel comparison of in situ Raman and NIR spectroscopies to simultaneously measure multiple variables toward real-time monitoring of CHO cell bioreactor cultures. Biochemical Engineering Journal, Elsevier, 2018, 137, pp.205 - 213. ⟨10.1016/j.bej.2018.06.005⟩. ⟨hal-01921094⟩
  • Abdoul Karim Kaboré, Stéphane Delaunay, Fabrice Blanchard, Emmanuel Guedon, Michel Fick, et al.. Study and modeling of fluctuating dissolved oxygen concentration impact on Corynebacterium glutamicum growth in a scale-down bioreactor. Process Biochemistry, Elsevier, 2018, ⟨10.1016/j.procbio.2018.10.016⟩. ⟨hal-01924081⟩
  • Felipe Buendia-Kandia, Guillain Mauviel, Emmanuel Guedon, Emmanuel Rondags, Dominique Petitjean, et al.. Decomposition of cellulose in hot-compressed water: detailed analysis of the products and effect of operating conditions. Energy and Fuels, American Chemical Society, 2017, ⟨10.1021/acs.energyfuels.7b02994⟩. ⟨hal-01651273⟩
  • Roman Akasov, Anastasia Gileva, Daria Zaytseva-Zotova, Sergey Burov, Isabelle Chevalot, et al.. 3D in vitro co-culture models based on normal cells and tumor spheroids formed by cyclic RGD-peptide induced cell self-assembly. Biotechnology Letters, Springer Verlag, 2017, 39 (1), pp.45 - 53. ⟨10.1007/s10529-016-2218-9⟩. ⟨hal-01921238⟩
  • Emmanuel Guedon. Foreword Advances in “Stem Cell Bioengineering”. Process Biochemistry, Elsevier, 2017, 59, pp.229 - 230. ⟨10.1016/j.procbio.2017.07.023⟩. ⟨hal-01924087⟩
  • Céline Martin, Eric Olmos, Marie-Laure Collignon, Natalia de Isla, Fabrice Blanchard, et al.. Revisiting MSC expansion from critical quality attributes to critical culture process parameters. Process Biochemistry, Elsevier, 2017, 59, pp.231 - 243. ⟨10.1016/j.procbio.2016.04.017⟩. ⟨hal-01921144⟩
  • Abdoul-Karim Kaboré, Eric Olmos, Michel Fick, Fabrice Blanchard, Emmanuel Guedon, et al.. Aerobiosis–anaerobiosis transition has a significant impact on organic acid production by Corynebacterium glutamicum. Process Biochemistry, Elsevier, 2017, 52, pp.10 - 21. ⟨10.1016/j.procbio.2016.10.007⟩. ⟨hal-01924060⟩
  • Franck Courtès, Bruno Ebel, Emmanuel Guedon, Annie Marc. A dual near-infrared and dielectric spectroscopies strategy to monitor populations of Chinese hamster ovary cells in bioreactor. Biotechnology Letters, Springer Verlag, 2016, 38 (5), pp.745 - 750. ⟨10.1007/s10529-016-2036-0⟩. ⟨hal-01921187⟩
  • Muhammad Imran, Anne-Marie Revol-Junelles, Cedric Paris, Emmanuel Guedon, Michel Linder, et al.. Liposomal nanodelivery systems using soy and marine lecithin to encapsulate food biopreservative nisin. LWT - Food Science and Technology, Elsevier, 2015, 62 (1, 1), pp.341-349. ⟨10.1016/j.lwt.2014.12.046⟩. ⟨hal-01267001⟩
  • Abdoul Karim Kabore, Eric Olmos, Fabrice Blanchard, Michel Fick, Stéphane Delaunay, et al.. Impact of gas-liquid mass transfer on organic acids production by Corynebacterium glutamicum in unbaffled shake flasks. Biochemical Engineering Journal, Elsevier, 2015, 101, pp.237-247. ⟨10.1016/j.bej.2015.06.003⟩. ⟨hal-01266260⟩
  • Hoang Bao Truc Khuat, Abdoul Karim Kabore, Eric Olmos, Michel Fick, Joseph Boudrant, et al.. Lactate production as representative of the fermentation potential of Corynebacterium glutamicum 2262 in a one-step process. Bioscience, Biotechnology and Biochemistry, Taylor & Francis, 2014, 78 (2), pp.343-349. ⟨10.1080/09168451.2014.878219⟩. ⟨hal-01276064⟩
  • Cédric Laurent, Cédryck Vaquette, Céline Martin, Emmanuel Guedon, Xiude Wu, et al.. Towards a Tissue-Engineered Ligament: Design and Preliminary Evaluation of a Dedicated Multi-Chamber Tension-Torsion Bioreactor. Processes, MDPI, 2014, 2 (1), pp.167. ⟨10.3390/pr2010167⟩. ⟨hal-01424974⟩
  • Caroline Ferrari, Eric Olmos, Frederique Balandras, Nguyen Tran, Isabelle Chevalot, et al.. Investigation of Growth Conditions for the Expansion of Porcine Mesenchymal Stem Cells on Microcarriers in Stirred Cultures. Applied Biochemistry and Biotechnology, Humana Press, 2014, 172 (2), pp.1004-1017. ⟨10.1007/s12010-013-0586-3⟩. ⟨hal-01276641⟩
  • Tatiana Pantsyrnaya, Stéphane Delaunay, Jean-Louis Goergen, Emmanuel Guedon, Cedric Paris, et al.. Biodegradation of Phenanthrene by Pseudomonas putida and a Bacterial Consortium in the Presence and in the Absence of a Surfactant. Indian Journal of Microbiology, Springer, 2012, 52 (3), pp.420-426. ⟨10.1007/s12088-012-0265-z⟩. ⟨hal-00777647⟩
  • Caroline Ferrari, Frederique Balandras, Emmanuel Guedon, Eric Olmos, Isabelle Chevalot, et al.. Limiting Cell Aggregation During Mesenchymal Stem Cell Expansion on Microcarriers. Biotechnology Progress, Wiley, 2012, 28 (3), pp.780-787. ⟨10.1002/btpr.1527⟩. ⟨hal-00777492⟩
  • T. Pantsyrnaya, F. Blanchard, S. Delaunay, J.L. Goergen, E. Guedon, et al.. Effect of surfactants, dispersion and temperature on solubility and biodegradation of phenanthrene in aqueous media.. Chemosphere, Elsevier, 2011, 83 ((1)), pp. 29-33. ⟨10.1016/j.chemosphere.2011.01.024⟩. ⟨hal-00604685⟩
  • T. Pantsyrnaya, F. Blanchard, S. Delaunay, J.L. Goergen, E. Guédon, et al.. Effect of surfactants, dispersion and temperature on solubility and biodegradation of phenanthrene in aqueous media. Chemosphere, Elsevier, 2011, 83 (1), pp.29-33. ⟨10.1016/j.chemosphere.2011.01.024⟩. ⟨hal-03060481⟩
  • M.F. Clincke, E. Guedon, F.T. Yen, V. Ogier, O. Roitel, et al.. Effect of surfactant pluronic F-68 on CHO cell growth, metabolism, production, and glycosylation of human recombinant IFN-γ in mild operating conditions. Biotechnology Progress, Wiley, 2011, 27 ((1)), pp. 181-190. ⟨10.1002/btpr.503⟩. ⟨hal-00606341⟩
  • O. Delumeau, F. Lecointe, J. Muntel, A. Guillot, E. Guedon, et al.. The dynamic protein partnership of RNA polymerase inBacillus subtilis.. Proteomics, Wiley-VCH Verlag, 2011, pp.2992-3001. ⟨hal-00610859⟩
  • Iief Limem-Ben Amor, Alain Hehn, Emmanuel Guedon, Kamel Ghedira, Jean-Marc Engasser, et al.. Biotransformation of Naringenin to Eriodictyol by Saccharomyces cerevisiea Functionally Expressing Flavonoid 3 ' Hydroxylase. Natural Product Communications , SAGE Publications, 2010, 5 (12), pp.1893 - 1898. ⟨hal-02663271⟩
  • Ilef Limen Ben Amor, Nidhal Salem, Emmanuel Guedon, Jean-Marc Engasser, Leila Chekir-Ghedira, et al.. Preliminary investigation of naringenin hydroxylation with recombinant E. coli expressing plant flavonoid hydroxylation gene. Natural Product Communications , SAGE Publications, 2010, 5 (5), pp.777-782. ⟨10.1177/1934578X1000500520⟩. ⟨hal-00799073⟩
  • Ilef Limen Ben Amor, Alain Hehn, Emmanuel Guedon, Kamel Ghedira, Jean-Marc Engasser, et al.. Biotransformation of Naringenin to Eriodictyol by Saccharomyces cerevisiea Functionally Expressing Flavonoid 3 ' Hydroxylase. Natural Product Communications , SAGE Publications, 2010, 5 (12), pp.1893-1898. ⟨10.1177/1934578X1000501211⟩. ⟨hal-00799067⟩
  • Kenza-Amel Boulahya,, Emmanuel Guedon, Stéphane Delaunay, Christian Schultz, Joseph Boudrant, et al.. OdhI dephosphorylation kinetics during different glutamate production processes involving Corynebacterium glutamicum. European Journal of Applied Microbiology and Biotechnology, Springer-Verlag, 2010, 87 (5), pp.1867-1874. ⟨10.1007/s00253-010-2599-y⟩. ⟨hal-00799151⟩
  • E. Petiot, E. Guedon, F. Blanchard, C. Gény, H. Pinton, et al.. Kinetic characterization of vero cell metabolism in a serum-free batch culture process. Biotechnology and Bioengineering, Wiley, 2010, 107 ((1)), pp. 143-153. ⟨10.1002/bit.22783⟩. ⟨hal-00611352⟩
  • I. Limem, I. Skandrani, J. Boubaker, M. Ben Sgaier, A. Neffati, et al.. Investigation of biological activity of polar extracts isolated from Phlomis crinita Cav ssp. mauritanica Munby. Drug and Chemical Toxicology, Taylor & Francis, 2009, 32 (1), pp.38-46. ⟨hal-00508044⟩
  • I. Limem, E. Guedon, A. Hehn, F. Bourgaud, L. Chekir Ghedira, et al.. Production of phenylpropanoid compounds by recombinant microorganisms expressing plant-specific biosynthesis genes. Process Biochemistry, Elsevier, 2008, 43 (5), pp.463-479. ⟨10.1016/j.procbio.2008.02.001⟩. ⟨hal-00379981⟩
  • N. Kochanowski, F. Blanchard, R. Cacan, F. Chirat, A. Marc, et al.. Influence of intracellular nucleotide and nucleotide sugar contents on recombinant interferon-gamma; glycosylation during batch and fed-batch cultures of CHO cells. Biotechnology and Bioengineering, Wiley, 2008, 100 (4), pp.721-733. ⟨10.1002/bit.21816⟩. ⟨hal-00379732⟩
  • N. Simeon, G. Mercier, J.F. Blais, S. Ouvrard, A. Cebron, et al.. Décontamination de sols pollués par les hydrocarbures aromatiques polycycliques par biodégradation en présence de substrats organiques supplémentaires. Revue du Génie et de la Science de l'Environnement, 2008, 7 (5), pp.467-479. ⟨10.1139/S08-027⟩. ⟨hal-00380365⟩
  • T. Nizhegorodova, E. Guseva, N. Menshutina, J. Boudrant, J.L. Goergen, et al.. Mathematical modeling of L-glutamic acid production. Izvestiya Vuzov. Seria Himiya i himicheskaya tehnologiya, 2007, 50, pp.93-98. ⟨hal-00278429⟩
  • D. Bokas, D. Uy, F. Grattepanche, G. Duportail, E. Guedon, et al.. Cell envelope fluidity modification for an affective glutamate excretion in Corynebacterium glutamicum 2262. Applied Microbiology and Biotechnology, Springer Verlag, 2007, 76, pp.773-781. ⟨hal-00171988⟩
  • D. Bokas, D. Uy, F. Grattepanche, G. Duportail, E. Guedon, et al.. Cell envelope fluidity modification for an effective glutamate excretion in Corynebacterium glutamicum 2262. Applied Microbiology and Biotechnology, Springer Verlag, 2007, 76 (4), pp.773-781. ⟨hal-00277816⟩
  • N. Kochanowski, F. Blanchard, R. Cacan, F. Chirat, E. Guedon, et al.. Intracellular nucleotide and nucleotide sugar contents of cultured CHO cells determined by a fast, sensitive, and high-resolution ion-pair RP-HPLC. Analytical Biochemistry, Elsevier Masson, 2006, 348 (2), pp.243-251. ⟨10.1016/j.ab.2005.10.027⟩. ⟨hal-00077315⟩
  • Emmanuel Guedon, Mickael Desvaux, Henri Petitdemange. Improvement of Cellulolytic Properties of Clostridium cellulolyticum by Metabolic Engineering. Applied and Environmental Microbiology, American Society for Microbiology, 2002, 68 (1), pp.53 - 58. ⟨10.1128/AEM.68.1.53-58.2002⟩. ⟨hal-02910792⟩
  • E. Guedon, C. Martin, F.X. Gobert, S.D. Ehrlich, P. Renault, et al.. Réseau de régulation de la transcription des gènes du système protéolytique de Lactococcus lactis. Lait, Elsevier, 2001, 81 (1-2), pp.65-74. ⟨hal-02674703⟩
  • Mickael Desvaux, Emmanuel Guedon, Henri Petitdemange. Carbon Flux Distribution and Kinetics of Cellulose Fermentation in Steady-State Continuous Cultures of Clostridium cellulolyticum on a Chemically Defined Medium. Journal of Bacteriology, American Society for Microbiology, 2001, 183 (1), pp.119-130. ⟨10.1128/JB.183.1.119-130.2001⟩. ⟨hal-02910799⟩
  • M. Desvaux, Emmanuel Guedon, Henri Petitdemange. Kinetics and Metabolism of Cellulose Degradation at High Substrate Concentrations in Steady-State Continuous Cultures of Clostridium cellulolyticum on a Chemically Defined Medium. Applied and Environmental Microbiology, American Society for Microbiology, 2001, 67 (9), pp.3837 - 3845. ⟨10.1128/AEM.67.9.3837-3845.2001⟩. ⟨hal-02910803⟩
  • Mickael Desvaux, Emmanuel Guedon, Henri Petitdemange. Metabolic flux in cellulose batch and cellulose-fed continuous cultures of Clostridium cellulolyticum in response to acidic environment. Microbiology, Microbiology Society, 2001, 147 (6), pp.1461-1471. ⟨10.1099/00221287-147-6-1461⟩. ⟨hal-02910800⟩
  • Emmanuel Guedon, Philippe Gerard, Bruno Charpentier, Christiane Branlant, Henri Petitdemange. Both pH and carbon flux influence the level of rubredoxin in Clostridium butyricum. Current Microbiology, Springer Verlag, 2001, 43 (6), pp.434-439. ⟨10.1007/s002840010334⟩. ⟨hal-01600080⟩
  • E. Guedon, P. Renault, S.D. Ehrlich, Christine Delorme. Evaluation de la diversité de l'expression génétique chez les lactocoques : développement d'un outil et son application aux peptidases. Sciences des Aliments, Lavoisier Abonnements, 2000, 20 (1), pp.55-62. ⟨hal-02684710⟩
  • Mickael Desvaux, Emmanuel Guedon, Henri Petitdemange. Cellulose Catabolism by Clostridium cellulolyticum Growing in Batch Culture on Defined Medium Downloaded from. Applied and Environmental Microbiology, American Society for Microbiology, 2000, 66 (6), pp.2461 - 2470. ⟨10.1128/AEM.66.6.2461-2470.2000⟩. ⟨hal-02910808⟩
  • Emmanuel Guedon, S. Payot, M Desvaux, H. Petitdemange. Relationships Between Cellobiose Catabolism, Enzyme Levels, and Metabolic Intermediates in Clostridium cellulolyticum Grown in a Synthetic Medium. Inc. Biotechnol Bioeng, 2000, 67, pp.327 - 335. ⟨hal-02910822⟩
  • Emmanuel Guedon, Mickael Desvaux, Henri Petitdemange. Kinetic Analysis of Clostridium cellulolyticum Carbohydrate Metabolism: Importance of Glucose 1-Phosphate and Glucose 6-Phosphate Branch Points for Distribution of Carbon Fluxes Inside and Outside Cells as Revealed by Steady-State Continuous Culture. Journal of Bacteriology, American Society for Microbiology, 2000, 182 (7), pp.2010-2017. ⟨10.1128/JB.182.7.2010-2017.2000⟩. ⟨hal-02910812⟩
  • O. Mohand-Oussaid, S. Payot, E. Guedon, E. Gelhaye, A. Youyou, et al.. The Extracellular Xylan Degradative System in Clostridium cellulolyticum Cultivated on Xylan: Evidence for Cell-Free Cellulosome Production. Journal of Bacteriology, American Society for Microbiology, 1999, 181 (13). ⟨hal-01787581⟩
  • Emmanuel Guedon, S. Payot, M. Desvaux, H. Petitdemange. Carbon and Electron Flow in Clostridium cellulolyticum Grown in Chemostat Culture on Synthetic Medium Downloaded from. Journal of Bacteriology, American Society for Microbiology, 1999, 181 (10), pp.3262 - 3269. ⟨10.1128/JB.181.10.3262-3269.1999⟩. ⟨hal-02910828⟩
  • Sophie Payot, Emmanuel Guedon, Eric Gelhaye, Henri Petitdemange. Induction of lactate production associated with a decrease in NADH cell content enables growth resumption of Clostridium cellulolyticum in batch cultures on cellobiose. Research in Microbiology, Elsevier, 1999, 150 (7), pp.465 - 473. ⟨10.1016/S0923-2508(99)00110-2⟩. ⟨hal-01787587⟩
  • E. Guedon, M. Desvaux, S. Payot, H. Petitdemange. Growth inhibition of Clostridium cellulolyticum by an inefficiently regulated carbon flow. Microbiology, Microbiology Society, 1999, 145 (8), pp.1831 - 1838. ⟨10.1099/13500872-145-8-1831⟩. ⟨hal-01787598⟩
  • S. Payot, Emmanuel Guedon, M. Desvaux, E. Gelhaye, E. Petitdemange. Effect of dilution rate, cellobiose and ammonium availabilities on Clostridium cellulolyticum sporulation. Applied Microbiology and Biotechnology, Springer Verlag, 1999, 52 (5), pp.670-674. ⟨10.1007/s002530051577⟩. ⟨hal-02910824⟩
  • P. Renault, S. Calero, Christine Delorme, S. Drouault, N. Goupil-Feuillerat, et al.. Du génome à l'application. Lait, Elsevier, 1998, 78, pp.39-52. ⟨hal-02684934⟩
  • S. Payot, E. Guedon, C. Cailliez, E. Gelhaye, H. Petitdemange. Metabolism of cellobiose by Clostridium cellulolyticum growing in continuous culture: evidence for decreased NADH reoxidation as a factor limiting growth. Microbiology, Microbiology Society, 1998, 144 (2), pp.375 - 384. ⟨10.1099/00221287-144-2-375⟩. ⟨hal-01787609⟩

Conference papers14 documents

  • Daniel Zavala-Ortiz, Mengyao Li, Maria Aguilar-Uscanga, Javier Gomez-Rodrigues, Dulce Barradas-Dermitz, et al.. Chemometrics to monitor CHO cell cultures quality by in situ NIRS. 26th ESACT meeting " Cell culture technologies: bridging academia and industry to provide solutions for patients", BMC Proceedings, May 2019, Copenhague, Denmark. ⟨hal-02333483⟩
  • Daniel Zavala-Ortiz, Mengyao Li, Maria Aguilar-Uscanga, Javier Gomez-Rodrigues, Dulce Barradas-Dermitz, et al.. Enhanced method to monitor cell cultures by dielectric spectroscopy. 26th ESACT meeting " Cell culture technologies: bridging academia and industry to provide solutions for patients", BMC Proceedings, May 2019, Copenhague, Denmark. ⟨hal-02333492⟩
  • Mengyao Li, Bruno Ebel, Cédric Paris, Fabien Chauchard, Emmanuel Guedon, et al.. Real-time analysis of antibody glycosylation using in-line Raman spectroscopy in cell culture. 3rd Conference on Process Optimization and Safety in Industry 4.0, Sep 2018, Paris, France. ⟨hal-01922497⟩
  • Mengyao Li, Bruno Ebel, Cédric Paris, Fabien Chauchard, Emmanuel Guedon, et al.. In situ Raman spectroscopy monitoring of macro and micro-heterogeneity of monoclonal antibody glycosylation produced by CHO cells in bioreactors. 5th BioProScale Symposium: Innovative scale up and scale down for bioprocess intensification, Mar 2018, Berlin, Germany. ⟨hal-01922509⟩
  • Mengyao Li, Bruno Ebel, Cédric Paris, Fabien Chauchard, Emmanuel Guedon, et al.. In situ Raman spectroscopy as a promising PAT tool for monitoring of macro and micro-heterogeneity of monoclonal antibody glycosylation produced by CHO cells in bioreactors. 5th BioProScale Symposium: Innovative scale up and scale down for bioprocess intensification, Mar 2018, Berlin, Germany. ⟨hal-02333510⟩
  • Mengyao Li, Bruno Ebel, Frantz Fournier, Emmanuel Guedon, Annie Marc. Online and real-time control of CHO cell specific growth rate throughout cultures in bioreactor. 25th ESACT meeting "Cell technologies for innovative therapies", BMC Proceedings 2017, 12 (Suppl 1):3-P134, May 2017, Lausanne, Switzerland. ⟨hal-01922275⟩
  • Franck Courtès, Bruno Ebel, Emmanuel Guedon, Annie Marc. Real-time monitoring of the physiological state of CHO cells in bioreactor by using a dual spectroscopic strategy. 24th European Society for Animal Cell Technology (ESACT) Meeting: C2P2: Cells, Culture, Patients, Products, May 2015, Barcelone, Spain. ⟨10.1186/1753-6561-9-S9-P48⟩. ⟨hal-01305628⟩
  • Céline Martin, Alexandre Piccini, Isabelle Chevalot, Eric Olmos, Emmanuel Guedon, et al.. Serum-free media for mesenchymal stem cells expansion on microcarriers. 24th European Society for Animal Cell Technology (ESACT) Meeting: C2P2: Cells, Culture, Patients, Products, May 2015, Barcelone, Spain. ⟨10.1186/1753-6561-9-S9-P70⟩. ⟨hal-01305688⟩
  • Éric Olmos, Abdoul Karim Kabore, Céline Martin, Marie-Laure Collignon, Isabelle Chevalot, et al.. Recent advances in the study of the hydrodynamics of bioreactors used for the culture of living cells. 9th international symposium on CAtalysis in MUltiphase Reactors, Dec 2014, Lyon, France. ⟨hal-01922581⟩
  • J. Boudrant, N. Barbouche, N. Mehmood, E. Olmos, S. Delaunay, et al.. Stress during cell culture processes. 13th International Biotechnology Symposium and Exhibition, Biotechnology for the Sustainability of Human Society, Oct 2008, DALIAN, China. ⟨hal-00401153⟩
  • N. Barbouche, E. Guedon, A. Marc, E. Olmos. Contraintes hydrodynamiques et culture de cellules animales en réacteur : quel rôle pour le copolymère Pluronic-68 ?. Colloque de la fédération Gay-Lussac "La chimie du et pour le vivant", Dec 2008, RENNES, France. ⟨hal-00401130⟩
  • E. Guedon, C. Martin, F.X. Gobert, S.D. Ehrlich, P. Renault, et al.. Réseau de régulation de la transcription des gènes du système protéolytique de Lactococcus lactis. 10. Colloque du Club des Bactéries Lactiques, Apr 2000, Strasbourg, France. ⟨hal-02825666⟩
  • Gerard Corthier, Sophie Gilbert, M.C. Muller, Christine Delorme, S. Drouault, et al.. Etude de l'adaptation de Lactococcus lactis a l'environnement digestif : approche génétique. Rencontres des Microbiologistes de l'INRA, Apr 1999, Dourdan, France. ⟨hal-02771131⟩
  • E. Guedon, P. Renault, S.D. Ehrlich, Christine Delorme. Evaluation de la diversité de l'expression génétique chez les lactocoques : développement d'un outil et son application aux peptidases. 9. Colloque du Club des Bactéries Lactiques, Oct 1998, Bourg-en-Bresse, France. ⟨hal-02835362⟩

Poster communications9 documents

  • Daniel Zavala-Ortiz, Bruno Ebel, Mengyao Li, Maria Aguilar-Uscanga, Javier Gomez-Rodrigues, et al.. Amélioration du suivi en temps réel de l’état physiologique de cellules CHO par spectroscopie diélectrique in situ et régression à vecteurs de support. 17ème Congrès de la Société Française de Génie des Procédés, Oct 2019, Nantes, France. ⟨hal-02333522⟩
  • Daniel Zavala-Ortiz, Bruno Ebel, Mengyao Li, Maria Aguilar-Uscanga, Javier Gomez-Rodrigues, et al.. Suivi en-ligne de la qualité d’anticorps produits par cellules CHO par spectrométrie NIR in situ couplée à une régression à vecteurs de support. 17ème Congrès de la Société Française de Génie des Procédés, Oct 2019, Nantes, France. ⟨hal-02333525⟩
  • Daniel Zavala-Ortiz, Dulce Barradas-Dermitz, Bruno Ebel, Emmanuel Guedon, Annie Marc, et al.. Interest of cell heterogeneity for the production of anticancer drugs vincristine and vinblastine by suspension cultures of Catharanthus roseus. 40th National Meeting of the AMIDIQ, "Challenges of chemical engineering for national development", May 2019, Hualtuco, Mexico. ⟨hal-02333533⟩
  • Daniel Zavala-Ortiz, Bruno Ebel, Mengyao Li, Dulce Barradas-Dermitz, Maria Aguilar-Uscanga, et al.. Interest of NIR spectroscopy to perform rapid analysis of medium compounds of Taxus globosa plant cells cultivated in suspension. 12th European Symposium on Biochemical Engineering Sciences, Sep 2018, Lisbonne, Portugal. ⟨hal-01922399⟩
  • Daniel Zavala-Ortiz, Bruno Ebel, Emmanuel Guedon, Annie Marc, Dulce Barradas-Dermitz, et al.. Interest of the Locally Weighted Regression to improve real-time monitoring of CHO and antibody quality by using in situ NIR spectroscopy. 12th European Symposium on Biochemical Engineering Sciences, Sep 2018, Lisbonne, Portugal. ⟨hal-01922411⟩
  • Daniel Zavala-Ortiz, Dulce Barradas-Dermitz, Bruno Ebel, Emmanuel Guedon, Annie Marc, et al.. Improvement of the production process of Taxus globosa S. cells by cellular synchronization for the subsequent production of the anti-cancer paclitaxel. Congrès de l'AMIDIQ (Academia Mexicana de Investigation y Docencia en Ingeniera Quimica), San José des Cabo, Mexique, 1 - 4 mai 2018, May 2018, San José des Cabo, Mexico. ⟨hal-01922390⟩
  • Mengyao Li, Bruno Ebel, Frantz Fournier, Emmanuel Guedon, Annie Marc. Intérêt de l'estimation en temps réel de la vitesse spécifique de croissance pour le pilotage de cultures de cellules animales. 16ème Congrès de la Société Française de Génie des Procédés, Jul 2017, Nancy, France. ⟨hal-01922378⟩
  • Franck Courtès, Bruno Ebel, Emmanuel Guedon, Annie Marc. Utilisation combinée de techniques spectroscopiques pour le suivi en ligne de l'état physiologique de cellules CHO cultivées en bioréacteur. 21èmes journées du Groupe Français de Spectroscopies Vibrationnelles, Jun 2015, Reims, France. ⟨hal-01922324⟩
  • Victor Corro, Patricia Hayward-Jones, Dulce Barradas-Dermitz, Anne Gschaedler, Bruno Ebel, et al.. Ethanol production monitoring during Pichia Stipitis yeasts fermentation using on-line near-infrared spectroscopy. 3rd European Congress of Applied Biotechnology, Oct 2015, Nice, France. ⟨hal-01922340⟩

Book sections4 documents

  • Mengyao Li, Bruno Ebel, Franck Courtès, Emmanuel Guedon, Annie Marc. In situ infrared spectroscopy as a PAT tool of great promise for real-time monitoring of animal cell culture processes. Journal of Analytical and Pharmaceutical Chemistry, 3, 2, 1065-70, 2016. ⟨hal-01922462⟩
  • Stéphane Delaunay, Abdoul Karim Kabore, Mickael Cregut, Huang Bao Truc Khuat, Emmanuel Guedon. Anaerobie production of organie acids and alcohols with Corynebacterium glutamicum. Carlos Barreiro. New trends in Corynebacterium glutamicum: beyond the amino acids, Nova Sciences Pub, 2015, 978-1-63483-280-9. ⟨hal-01962320⟩
  • Annie Marc, Emmanuel Guedon, Eric Olmos, Fabrice Blanchard, Isabelle Chevalot. Défis de la culture de cellules animales en bioréacteur. Culture de cellules animales, 3ème édition (eds. G. Barlovatz-Meimon, X. Ronot), pp. 61-70. Tec&Doc, Lavoisier, Paris, 2014. ⟨hal-01922265⟩
  • M.F. Clincke, Emmanuel Guedon, Jean-Louis Goergen. Procédés biotechnologiques pour la production de protéines recombinantes à usage thérapeutiques : vers une maîtrise de la glycosylation. Traité Bioprocédés, Techniques de l'Ingénieur, BIO 6 200 p. 1-19, 2011. ⟨hal-00822941⟩

Theses1 document

  • Emmanuel Guedon. Analyse du Métabolisme de Clostridium cellulolyticum. Importance des Débordements Cataboliques dans la Distribution du Flux du Carbone et des Électrons. Biochimie, Biologie Moléculaire. Université Henri Poincaré - Nancy 1, 2000. Français. ⟨NNT : 2000NAN10121⟩. ⟨tel-01746476⟩