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Bioengineered AAV vectors with increased skeletal muscle potency and specificity for systemic gene therapy of myotubular myopathy

Edith Renaud-Gabardos , Elandari Jihad , Louise Mangin , Weinmann Jonas , Esther Attebi , et al.
ESGCT, 2021, PARIS, France
Poster de conférence hal-04488882v1

Periprostatic Adipose Tissue Favors Prostate Cancer Cell Invasion in an Obesity-Dependent Manner: Role of Oxidative Stress

Victor Laurent , Aurélie Toulet , Camille Attané , Delphine Milhas , Stéphanie Dauvillier , et al.
Molecular Cancer Research, 2019, 17 (3), pp.821-835. ⟨10.1158/1541-7786.MCR-18-0748⟩
Article dans une revue hal-03121906v1
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Therapeutic Benefits and Adverse Effects of Combined Pro-Angiogenic Gene Therapy in Mouse Critical Leg Ischemia.

Benoît Lebas , Julien Galley , Edith Renaud-Gabardos , Françoise Pujol , Françoise Lenfant , et al.
Annals of Vascular Surgery, 2016, pii: S0890-5096(16)31264-X. Epub ahead of print. ⟨10.1016/j.avsg.2016.08.027⟩
Article dans une revue inserm-01424778v1

Therapeutic Benefit and Gene Network Regulation by Combined Gene Transfer of Apelin, FGF2, and SERCA2a into Ischemic Heart

Edith Renaud-Gabardos , Florence Tatin , Fransky Hantelys , Benoît Lebas , Denis Calise , et al.
Molecular Therapy, 2018, 26 (3), pp.902-916. ⟨10.1016/j.ymthe.2017.11.007⟩
Article dans une revue hal-02924122v1

Apelin modulates pathological remodeling of lymphatic endothelium after myocardial infarction

Florence Tatin , Edith Renaud-Gabardos , Anne-Claire Godet , Fransky Hantelys , Françoise Pujol , et al.
JCI Insight, 2017, 2 (12), ⟨10.1172/jci.insight.93887⟩
Article dans une revue hal-02393140v1

Internal ribosome entry site-based vectors for combined gene therapy

Edith Renaud-Gabardos , Fransky Hantelys , Florent Morfoisse , Xavier Chaufour , Barbara Garmy-Susini , et al.
World Journal of Experimental Medicine, 2015, 5 (1), pp.11-20. ⟨10.5493/wjem.v5.i1.11⟩
Article dans une revue hal-03121893v1
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Promoter-Dependent Translation Controlled by p54nrb and hnRNPM during Myoblast Differentiation

Nadera Ainaoui , Fransky Hantelys , Edith Renaud-Gabardos , Morgane Bunel , Frédéric Lopez , et al.
PLoS ONE, 2015, 10 (9), pp.e0136466. ⟨10.1371/journal.pone.0136466⟩
Article dans une revue hal-03121844v1
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Biodistribution of AAVpo1 and AAVpo1A1 in mice with myotubular myopathy

Edith Renaud-Gabardos , Paloma Navas-Navarro , Jihad Elandari , Louise Mangin , Karine Poulard , et al.
ASGCT 2020, May 2020, Boston (MA), United States
Poster de conférence hal-04442079v1

AAV-Mediated Gene Transfer Restores a Normal Muscle Transcriptome in a Canine Model of X-Linked Myotubular Myopathy

Jean-Baptiste Dupont , Jianjun Guo , Edith Renaud-Gabardos , Karine Poulard , Virginie Latournerie , et al.
Molecular Therapy, 2020, 28 (2), pp.382-393. ⟨10.1016/j.ymthe.2019.10.018⟩
Article dans une revue hal-04291348v1

Use of a synthetic AAV capsid for gene therapy of muscle and central nervous system disorders

Ana Buj-Bello , Edith Renaud-Gabardos
France, Patent n° : EP20305412.7. 2020
Brevet hal-04482827v1
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Bioengineered AAV vectors with increased skeletal muscle potency and specificity for systemic gene therapy

Edith Renaud-Gabardos , Jihad El Andari , Louise Mangin Jonas Weinmann , Esther Attebi , Emanuele Bourges , et al.
ASGCT 2022, May 2022, Washington DC, United States
Poster de conférence hal-04442173v1

Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders

Jihad El Andari , Edith Renaud-Gabardos , Warut Tulalamba , Jonas Weinmann , Louise Mangin , et al.
Science Advances , 2022, 8 (38)
Article dans une revue hal-04273243v1

Vasohibin1, a new mouse cardiomyocyte IRES trans-acting factor that regulates translation in early hypoxia

Fransky Hantelys , Anne-Claire Godet , Florian David , Florence Tatin , Edith Renaud-Gabardos , et al.
Article dans une revue hal-03104359v1
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Peptide-displaying chimeric AAV vectors with increased skeletal muscle potency and liver detargeting for systemic gene therapy

Edith Renaud-Gabardos , Jihad El Andari , Louise Mangin , Jonas Weinmann , Esther Attebi , et al.
Myology 2022, Sep 2022, Nice, France
Poster de conférence hal-04442190v1

AAV-Mediated Gene Transfer Restores a Normal Muscle Transcriptome in a Canine Model of X-Linked Myotubular Myopathy

J. B. Dupont , J. Guo , E. Renaud-Gabardos , K. Poulard , V. Latournerie , et al.
Molecular Therapy, 2020, 28, pp.382-393. ⟨10.1016/j.ymthe.2019.10.018⟩
Article dans une revue hal-02880796v1

Administration of a recombinant AAVpo1A1 vector expressing MTM1 corrects skeletal muscle pathology with detargeted liver transduction in myotubular myopathy mice

Edith Renaud-Gabardos , Célia Sourd , Louise Mangin , Paloma Navas-Navarro , Jonas Weinmann , et al.
ESGCT, Oct 2021, Online, France
Poster de conférence hal-04484212v1

Adaptation de la synthèse protéique du VEGF-C par les cellules tumorales en condition hypoxique

Florent Morfoisse , Edith Renaud-Gabardos , Fransky Hantelys , Anne-Catherine Prats , Barbara Garmy-Susini
Médecine/Sciences, 2014, 30 (5), pp.506-508. ⟨10.1051/medsci/20143005010⟩
Article dans une revue hal-03121829v1

Local production of tenascin-C acts as a trigger for monocyte/macrophage recruitment that provokes cardiac dysfunction

Dounia Abbadi , Fanny Laroumanie , Mathilde Bizou , Joffrey Pozzo , Danièle Daviaud , et al.
Cardiovascular Research, 2018, 114 (1), pp.123-137. ⟨10.1093/cvr/cvx221⟩
Article dans une revue hal-02411881v1

Role of hypoxia and vascular endothelial growth factors in lymphangiogenesis

Florent Morfoisse , Edith Renaud-Gabardos , Fransky Hantelys , Anne-Catherine Prats , Barbara Garmy-Susini
Molecular & Cellular Oncology, 2015, 2 (4), pp.e1024821. ⟨10.1080/23723556.2015.1024821⟩
Article dans une revue hal-03121812v1