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Metronomic Reloaded: Theoretical Models Bringing Chemotherapy into the Era of Precision Medicine

 Sébastien Benzekry , Eddy Pasquier , Dominique Barbolosi , Bruno Lacarelle , Fabrice Barlési , et al.
Seminars in Cancer Biology, 2015, pp.23. ⟨10.1016/j.semcancer.2015.09.002⟩
Article dans une revue hal-01195547v1

Akt targeting as a strategy to boost chemotherapy efficacy in non-small cell lung cancer through metabolism suppression.

 Marion Le Grand , Raphael Berges , Eddy G Pasquier , Marie-Pierre Montero , Laurence Borge , et al.
Scientific Reports, 2017, pp.45136. ⟨10.1038/srep45136⟩
Article dans une revue hal-01771176v1
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Targeting Mitochondrial Complex I Overcomes Chemoresistance in High OXPHOS Pancreatic Cancer

 Rawand Masoud , Gabriela Reyes-Castellanos , Sophie Lac , Julie Garcia , Samir Dou , et al.
Cell Reports Medicine, 2020, 1 (8), pp.100143. ⟨10.1016/j.xcrm.2020.100143⟩
Article dans une revue hal-03097443v1

Metronomic Chemotherapy: Direct Targeting of Cancer Cells after all?

 Manon Carré , Nicolas André , Kelvin Tsai , Eddy Pasquier
Trends in Cancer, 2017, 3 (5), pp.319 - 325. ⟨10.1016/j.trecan.2017.03.011⟩
Article dans une revue hal-01821573v1
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Metronomics: Intrinsic Anakoinosis Modulator?

 Andre Nicolas , Manon Carre , Eddy Pasquier
Frontiers in Pharmacology, 2018, 9, ⟨10.3389/fphar.2018.00689⟩
Article dans une revue hal-02143611v1
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R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma

 Jeroen Overman , Frank Fontaine , Jill Wylie-Sears , Mehdi Moustaqil , Lan Huang , et al.
eLife, 2019, 8, ⟨10.7554/eLife.43026⟩
Article dans une revue hal-02366464v1
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CRCM5484: A BET- BDII Selective Compound With Differential Anti-Leukemic Drug Modulation

 Kendall Carrasco , Camille Montersino , Carine Derviaux , Magali Saez-Ayala , Laurent Hoffer , et al.
Journal of Medicinal Chemistry, 2022, pp.acs.jmedchem.1c02168. ⟨10.1021/acs.jmedchem.1c02168⟩
Article dans une revue hal-03624836v1
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H3.3K27M Mutation Controls Cell Growth and Resistance to Therapies in Pediatric Glioma Cell Lines

 Andria Rakotomalala , Quentin Bailleul , Clara Savary , Mélanie Arcicasa , Maud Hamadou , et al.
Cancers, 2021, 13 (21), pp.5551. ⟨10.3390/cancers13215551⟩
Article dans une revue hal-03418323v1

Tuning the properties of a cyclic RGD-containing tetrapeptide through backbone fluorination

 Catherine Au , Christina Gonzalez , Yun Cheuk Leung , Flora Mansour , Johny Trinh , et al.
Organic & Biomolecular Chemistry, 2019, 17 (3), pp.664-674. ⟨10.1039/c8ob02679c⟩
Article dans une revue hal-02503849v1

Combination drug screen targeting glioblastoma core vulnerabilities reveals pharmacological synergisms

 Jérémy Ariey-Bonnet , Raphael Berges , Marie-Pierre Montero , Baptiste Mouysset , Patricia Piris , et al.
EBioMedicine, 2023, 95, pp.104752. ⟨10.1016/j.ebiom.2023.104752⟩
Article dans une revue hal-04204691v1
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Metronomic Chemotherapy Modulates Clonal Interactions to Prevent Drug Resistance in Non-Small Cell Lung Cancer

 Maryna Bondarenko , Marion Le Grand , Yuval Shaked , Ziv Raviv , Guillemette Chapuisat , et al.
Cancers, 2021, 13, ⟨10.3390/cancers13092239⟩
Article dans une revue hal-03267511v1
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Drug repurposing in malignant pleural mesothelioma: a breath of fresh air?

 Arnaud Boyer , Eddy Pasquier , Pascale Tomasini , Joseph Ciccolini , Laurent Greillier , et al.
EUROPEAN RESPIRATORY REVIEW, 2018, 27 (147), ⟨10.1183/16000617.0098-2017⟩
Article dans une revue hal-02143583v1
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Poly-pharmacology of existing drugs: How to crack the code?

 Baptiste Mouysset , Marion Le Grand , Luc Camoin , Eddy Pasquier
Cancer Letters, 2024, 588, pp.216800. ⟨10.1016/j.canlet.2024.216800⟩
Article dans une revue hal-04539952v1
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Can metronomic maintenance with weekly vinblastine prevent early relapse/progression after bevacizumab-irinotecan in children with low-grade glioma?

 Marie Amélie Heng , Laetitia Padovani , Philippe Dory-Lautrec , Jean Claude Gentet , Arnaud Verschuur , et al.
Cancer Medicine, 2016, 5 (7), pp.1542-1545. ⟨10.1002/cam4.699⟩
Article dans une revue hal-01478943v1
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Predicting Synergism of Cancer Drug Combinations Using NCI-ALMANAC Data

 Pavel Sidorov , Stefan Naulaerts , Jérémy Ariey-Bonnet , Eddy Pasquier , Pedro J Ballester
Frontiers in Chemistry, 2019, 7, ⟨10.3389/fchem.2019.00509⟩
Article dans une revue hal-02366466v1
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Metronomic Maintenance for High-Risk Pediatric Malignancies: One Size Will Not Fit All

 Nicolas André , Daniel Orbach , Eddy Pasquier
Trends in Cancer, 2020, 6 (10), pp.819-828. ⟨10.1016/j.trecan.2020.05.007⟩
Article dans une revue hal-02989369v1
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Metronomic Chemotherapy for Children in Low- and Middle-Income Countries: Survey of Current Practices and Opinions of Pediatric Oncologists

 Gabriel Revon-Rivière , Shripad Banavali , Laila Heississen , Wendy Gomez Garcia , Babak Abdolkarimi , et al.
Journal of Global Oncology, 2019, 5, pp.1-8. ⟨10.1200/JGO.18.00244⟩
Article dans une revue hal-02366469v1
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Lessons from the Fourth Metronomic and Anti-angiogenic Therapy Meeting, 24–25 June 2014, Milan

 Gauthier Bouche , Nicolas André , Shripad Banavali , Frank Berthold , Alfredo Berruti , et al.
Ecancer medical science/Ecancermedicalscience - http://www-ncbi-nlm-nih-gov.gate2.inist.fr/pmc/journals/899/ - http://www.ecancer.org/ecms, 2014, 8, pp.463. ⟨10.3332/ecancer.2014.463⟩
Article dans une revue inserm-01867014v1
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Next generation metronomic chemotherapy - report from the Fifth Biennial International Metronomic and Anti-angiogenic Therapy Meeting, 6 - 8 May 2016, Mumbai

 Pan G Pantziarka , Lisa Hutchinson , Nicolas G André , Sébastien Benzekry , Francesco Bertolini , et al.
Ecancermedicalscience, 2016, 10, ⟨10.3332/ecancer.2016.689⟩
Article dans une revue hal-01392473v1

ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma

 Evangeline R Jackson , Ryan J Duchatel , Dilana E Staudt , Mika L Persson , Abdul Mannan , et al.
Cancer Research, 2023, 83 (14), pp.2421-2437. ⟨10.1158/0008-5472.can-23-0186⟩
Article dans une revue hal-04295392v1
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Combination drug screen targeting glioblastoma core vulnerabilities reveals pharmacological synergisms

 Jérémy Ariey-Bonnet , Raphael Berges , Marie-Pierre Montero , Baptiste Mouysset , Patricia Piris , et al.
EBioMedicine, 2023, pp.104752. ⟨10.1016/j.ebiom.2023.104752⟩
Article dans une revue hal-04296812v1
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Maintenance chemotherapy in children with ALL exerts metronomic-like thrombospondin-1 associated anti-endothelial effect

 Nicolas Andre , Sylvie Cointe , Vincent Barlogis , Laurent Arnaud , Romaric Lacroix , et al.
Oncotarget, 2015, 6 (26), ⟨10.18632/oncotarget.3984⟩
Article dans une revue hal-01787272v1
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MVL-PLA2, a snake venom phospholipase A2, inhibits angiogenesis through an increase in microtubule dynamics and disorganization of focal adhesions

 Amine Bazaa , Eddy Pasquier , Céline Defilles , Ines Limam , Raoudha Kessentini-Zouari , et al.
PLoS ONE, 2010, 5 (4), pp.e10124. ⟨10.1371/journal.pone.0010124⟩
Article dans une revue pasteur-00604861v1
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In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor

 Jeremy Ariey‐bonnet , Kendall Carrasco , Marion Le Grand , Laurent Hoffer , Stéphane Betzi , et al.
Molecular Oncology, 2020, 14, pp.3083 - 3099. ⟨10.1002/1878-0261.12810⟩
Article dans une revue hal-02989358v1
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Targeted therapy with propranolol and metronomic chemotherapy combination: sustained complete response of a relapsing metastatic angiosarcoma

 Shripad Banavali , Eddy Pasquier , Nicolas Andre
Ecancermedicalscience, 2015, 9, ⟨10.3332/ecancer.2015.499⟩
Article dans une revue hal-01420003v1

Pharmacokinetics and Pharmacodynamics-Based Mathematical Modeling Identifies an Optimal Protocol for Metronomic Chemotherapy

 Joseph Ciccolini , Dominique Barbolosi , Christophe Meille , Cindy Serdjebi , Sarah Giacometti , et al.
Cancer Research, 2017, 77 (17), pp.4723-4733. ⟨10.1158/0008-5472.CAN-16-3130⟩
Article dans une revue hal-01789578v1
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The beta adrenergic receptor antagonist propranolol alters mitogenic and apoptotic signaling in late stage breast cancer

 Alexa Montoya , Armando Varela-Ramirez , Erin Dickerson , Eddy Pasquier , Alireza Torabi , et al.
Biomedical journal, 2019, 42 (3), pp.155-165. ⟨10.1016/j.bj.2019.02.003⟩
Article dans une revue hal-02366472v1
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