|
Synthesis and Photochemical Properties of Fluorescent Metabolites Generated from Fluorinated Benzoylmenadiones in Living Cells
Nathan Trometer
,
Bogdan Cichocki
,
Quentin Chevalier
,
Jérémy Pécourneau
,
Jean-Marc Strub
Article dans une revue
hal-04157610v1
|
|
Efficient Multigram-Scale Synthesis of 7-Substituted 3-Methyltetral-1-ones and 6-Fluoromenadione
Nathan Trometer
,
Matthieu Roignant
,
Elisabeth Davioud-Charvet
Article dans une revue
hal-03584209v1
|
|
Evaluation of ferrocenyl-containing gamma-hydroxy-gamma-lactam-derived tetramates as potential antiplasmodials
Maurice Médebielle
,
Mourad Elhabiri
,
Elisabeth Davioud-Charvet
,
J.-P. Bouillon
,
Stéphane Picot
European Journal of Medicinal Chemistry, 2022
Article dans une revue
hal-03826853v1
|
|
Evaluation of ferrocenyl-containing γ-hydroxy-γ-lactam-derived tetramates as potential antiplasmodials
Nicolas Chopin
,
Julien Bosson
,
Shinya Iikawa
,
Stéphane Picot
,
Anne-Lise Bienvenu
Article dans une revue
hal-03798632v1
|
|
Magnesium Complexes of Ladanein: A Beneficial Strategy for Stabilizing Polyphenolic Antivirals
Xavier Martin‐benlloch
,
Don Antoine Lanfranchi
,
Sibylle Haid
,
Thomas Pietschmann
,
Elisabeth Davioud‐charvet
Article dans une revue
hal-03357249v1
|
|
The parasitophorous vacuole nutrient channel is critical for drug access in malaria parasites and modulates the artemisinin resistance fitness cost
Paolo Mesén-Ramírez
,
Bärbel Bergmann
,
Mourad Elhabiri
,
Lei Zhu
,
Heidrun von Thien
Article dans une revue
hal-03544974v1
|
|
A Class of Valuable (Pro-)Activity-Based Protein Profiling Probes: Application to the Redox-Active Antiplasmodial Agent, Plasmodione
Bogdan Cichocki
,
Vrushali Khobragade
,
Maxime Donzel
,
Leandro Cotos Munoz
,
Stephanie Blandin
Article dans une revue
hal-03243960v1
|
|
Plasmodium falciparum Ferredoxin-NADP + Reductase-Catalyzed Redox Cycling of Plasmodione Generates Both Predicted Key Drug Metabolites: Implication for Antimalarial Drug Development
Bogdan Cichocki
,
Maxime Donzel
,
Kim C. Heimsch
,
Mindaugas Lesanavičius
,
Liwen Feng
Article dans une revue
hal-03243991v1
|
|
Recent Advances in Direct C‐H Radical Alkylation of 1,4‐Quinones
Maxime Donzel
,
Deniz Karabiyikli
,
Leandro Cotos Munoz
,
Mourad Elhabiri
,
Elisabeth Davioud-Charvet
Article dans une revue
hal-03249134v1
|
|
Bioinspired Photoredox Benzylation of Quinones
Maxime Donzel
,
Mourad Elhabiri
,
Elisabeth Davioud-Charvet
Article dans une revue
hal-03369963v1
|
|
A role for the succinate dehydrogenase in the mode of action of the redox-active antimalarial drug, plasmodione
Pierre Mounkoro
,
Thomas Michel
,
Marie-Pierre Golinelli-Cohen
,
Stephanie Blandin
,
Elisabeth Davioud-Charvet
Article dans une revue
hal-03026255v1
|
|
Repurposing Auranofin and Evaluation of a New Gold(I) Compound for the Search of Treatment of Human and Cattle Parasitic Diseases: From Protozoa to Helminth Infections
Liwen Feng
,
Sébastien Pomel
,
Perle Latre de Late
,
Alexandre Taravaud
,
Philippe M Loiseau
Article dans une revue
hal-03038691v1
|
|
Antiplasmodial Activity of Nitroaromatic Compounds: Correlation with Their Reduction Potential and Inhibitory Action on Plasmodium falciparum Glutathione Reductase
Audronė Marozienė
,
Mindaugas Lesanavičius
,
Elisabeth Davioud-Charvet
,
Alessandro Aliverti
,
Philippe Grellier
Article dans une revue
hal-03038823v1
|
|
Investigating the mode of action of the redox-active antimalarial drug plasmodione using the yeast model
Pierre Mounkoro
,
Thomas Michel
,
Stéphanie Blandin
,
Marie-Pierre Golinelli-Cohen
,
Elisabeth Davioud-Charvet
Article dans une revue
hal-02170571v1
|
|
Author Correction: Arylmethylamino steroids as antiparasitic agents
Reimar Krieg
,
Esther Jortzik
,
Alice-Anne Goetz
,
Stéphanie Blandin
,
Sergio Wittlin
Article dans une revue
hal-02325972v1
|
|
Selenium Status in Elderly People: Longevity and Age-Related Diseases
Harry Robberecht
,
Tess de Bruyne
,
Elisabeth Davioud-Charvet
,
John Mackrill
,
Nina Hermans
Article dans une revue
hal-02325568v1
|
|
Physicochemical Properties Govern the Activity of Potent Antiviral Flavones
Xavier Martin-Benlloch
,
Sibylle Haid
,
Alexandra Novodomska
,
Frank Rominger
,
Thomas Pietschmann
Article dans une revue
hal-02325555v1
|
|
A Mild and Versatile Friedel‐Crafts Methodology for the Diversity‐Oriented Synthesis of Redox‐Active 3‐Benzoylmenadiones with Tuneable Redox Potentials
Leandro Cotos
,
Maxime Donzel
,
Mourad Elhabiri
,
Elisabeth Davioud-Charvet
Article dans une revue
hal-02408960v1
|
|
AntiMalarial Mode of Action (AMMA) Database: Data Selection, Verification and Chemical Space Analysis
Pavel Sidorov
,
Elisabeth Davioud-Charvet
,
Gilles Marcou
,
Dragos Horvath
,
Alexandre Varnek
Article dans une revue
hal-02325960v1
|
|
Synthesis of plasmodione metabolites and 13C-enriched plasmodione as chemical tools for drug metabolism investigation
Liwen Feng
,
Don Antoine Lanfranchi
,
Leandro Cotos Munoz
,
Elena Cesar Rodo
,
Katharina Ehrhardt
Article dans une revue
hal-02161631v1
|
|
Iron(iii) coordination properties of ladanein, a flavone lead with a broad-spectrum antiviral activity
Xavier Martin Benlloch
,
D Jacquemin
,
Elisabeth Davioud-Charvet
,
Mourad Elhabiri
,
A Novodomska
Article dans une revue
hal-02161640v1
|
|
Pharmacomodulation of the antimalarial plasmodione: synthesis of biaryl- and N-arylalkylamine analogues, antimalarial activities and physicochemical properties
Karène Urgin
,
Mouhamad Jida
,
Katharina Ehrhardt
,
T Müller
,
M Lanzer
Article dans une revue
hal-02177398v1
|
|
A Redox-Active Fluorescent pH Indicator for Detecting Plasmodium falciparum Strains with Reduced Responsiveness to Quinoline Antimalarial Drugs
Mouhamad Jida
,
Cecilia Sanchez
,
Karène Urgin
,
Katharina Ehrhardt
,
S Mounien
Article dans une revue
hal-02177403v1
|
|
Arylmethylamino steroids as novel antiparasitic agents
R Krieg
,
E Jortzik
,
Alice-Anne Goetz
,
Stephanie Blandin
,
S Wittlin
Article dans une revue
hal-02158243v1
|
|
A high susceptibility to redox imbalance of the transmissible stages of Plasmodium falciparum revealed with a luciferase-based mature gametocyte assay
G Siciliano
,
T Kumar
,
R Bona
,
G Camarda
,
M Calabretta
Article dans une revue
hal-02161655v1
|
|
QSAR modeling1. and chemical space analysis of antimalarial compounds
Pavel Sidorov
,
B Viira
,
Elisabeth Davioud-Charvet
,
U Maran
,
Gilles Marcou
Article dans une revue
hal-02177404v1
|
|
The Redox Cycler Plasmodione Is a Fast-Acting Antimalarial Lead Compound with Pronounced Activity against Sexual and Early Asexual Blood-Stage Parasites
Katharina Ehrhardt
,
Christiane Deregnaucourt
,
Alice-Anne Goetz
,
Tzvetomira Tzanova
,
Valentina Gallo
Article dans une revue
hal-01455775v1
|
|
Redox Polypharmacology as an Emerging Strategy to Combat Malarial Parasites
Pavel Sidorov
,
Israel Desta
,
Matthieu Chessé
,
Dragos Horvath
,
Gilles Marcou
Article dans une revue
hal-03151671v1
|
|
In Silico Mining for Antimalarial Structure-Activity Knowledge and Discovery of Novel Antimalarial Curcuminoids
Birgit Viira
,
Thibault Gendron
,
Don Antoine Lanfranchi
,
Sandrine Cojean
,
Dragos Horvath
Article dans une revue
hal-03150675v1
|
|
A Platform of Regioselective Methodologies to Access to Polysubstituted 2-Methyl-1,4-Naphthoquinones Derivatives: Scope and Limitations
Elena Cesar Rodo
,
Liwen Feng
,
Mouhamad Jida
,
Katharina Ehrhardt
,
Max Bielitza
Article dans une revue
hal-03537379v1
|
|
Double-drug development against antioxidant enzymes from Plasmodium falciparum
Christophe Biot
,
Jean Dessolin
,
Philippe Grellier
,
Elisabeth Davioud-Charvet
Article dans une revue
mnhn-02867482v1
|
|
Exploring the trifluoromenadione core as a template to design antimalarial redox-active agents interacting with glutathione reductase
D.A. Lanfranchi
,
D. Belorgey
,
T. Müller
,
H. Vezin
,
M. Lanzer
Article dans une revue
hal-00702812v1
|
|
A Glutathione Reductase-Catalyzed Cascade of Redox Reactions to Bioactivate Potent Antimalarial 1,4-Naphthoquinones - A New Strategy to Combat Malarial Parasites
Tobias Müller
,
Laure Johann
,
Beate Jannack
,
Margit Brückner
,
Don Antoine Lanfranchi
Article dans une revue
hal-03406270v1
|
|
Antimalarial activities of ferroquine conjugates with either glutathione reductase inhibitors or glutathione depletors via a hydrolyzable amide linker
Natascha Chavain
,
Elisabeth Davioud-Charvet
,
Xavier Trivelli
,
Linda Mbeki
,
M. Rottmann
Article dans une revue
hal-00642006v1
|
|
The aza-analogues of 1,4-naphthoquinones are potent substrates and inhibitors of plasmodial thioredoxin and glutathione reductases and of human erythrocyte glutathione reductase
Christophe Morin
,
Tatiana Besset
,
Jean-Claude Moutet
,
Martine Fayolle
,
Margit Brückner
Article dans une revue
hal-02541797v1
|
|
A Fluoro Analogue of the Menadione Derivative 6-[2‘-(3‘-Methyl)-1‘,4‘-naphthoquinolyl]hexanoic Acid Is a Suicide Substrate of Glutathione Reductase. Crystal Structure of the Alkylated Human Enzyme†
Holger Bauer
,
Karin Fritz-Wolf
,
Andreas Winzer
,
Sebastian Kühner
,
Susan Little
Journal of the American Chemical Society, 2006, The Journal of physical chemistry, 128 (33), pp.10784-10794. ⟨10.1021/ja061155v⟩
Article dans une revue
hal-03378811v1
|
|
Undressing of Phosphine Gold(I) Complexes as Irreversible Inhibitors of Human Disulfide Reductases
Sabine Urig
,
Karin Fritz-Wolf
,
Régis Réau
,
Christel Herold-Mende
,
Katalin Tóth
Article dans une revue
hal-01090379v1
|
|
Trypanosoma cruzi prolyl oligopeptidase Tc80 is involved in nonphagocytic mammalian cell invasion by trypomastigotes.
P. Grellier
,
S. Vendeville
,
R. Joyeau
,
I. M. D. Bastos
,
H. Drobecq
Journal of Biological Chemistry, 2001, 276, pp.47078-47086
Article dans une revue
hal-00086392v1
|
|
Glutathione-dependent activities of $Trypanosoma\ cruzi$ p52 makes it a new member of the thiol:disulphide oxidoreductase family
Mireille Moutiez
,
Eric Quéméneur
,
Christian Sergheraert
,
Valérie Lucas
,
André Tartar
Article dans une revue
hal-03637701v1
|
|
High sensitivity to auxin is a common feature of hairy root
W.H. Shen
,
E. Davioud
,
C. David
,
H. Barbier-Brygoo
Plant Physiology, 1990, 94, pp.554-560
Article dans une revue
hal-02713794v1
|
|
Production of indole alkaloids by in vitro root cultures from Catharanthus trichophyllus
E. Davioud
,
C. Kan
,
J. Hamon
,
J. Tempe
,
H.P. Husson
Phytochemistry, 1989, 28 (10), pp.2675-2680
Article dans une revue
hal-02722026v1
|
|
Cucumopine. A new T-DNA- encoded opine in hairy root and crown-gall
E. Davioud
,
A. Petit
,
M.E. Tate
,
M.H. Ryder
,
J. Tempe
Phytochemistry, 1988, 27 (8), pp.2429-2433
Article dans une revue
hal-02727299v1
|
|
Structure and synthesis of cucumopine, a new crown gall and hairy-root opine
E. Davioud
,
J.C. Quirion
,
M.E. Tate
,
J. Tempe
,
H.P. Husson
Heterocycles, 1988, 27 (10), n.p
Article dans une revue
hal-02716461v1
|