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TORC1 and TORC2 converge to regulate the SAGA co‐activator in response to nutrient availability

Thomas Laboucarié , Dylane Detilleux , Ricard Rodriguez-Mias , Céline Faux , Yves Romeo , et al.
EMBO Reports, 2017, 18 (12), pp.2197-2218. ⟨10.15252/embr.201744942⟩
Article dans une revue hal-02371827v1
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The Hos2 Histone Deacetylase Controls Ustilago maydis Virulence through Direct Regulation of Mating-Type Genes

Alberto Elías-Villalobos , Alfonso Fernández-Álvarez , Ismael Moreno-Sánchez , Dominique Helmlinger , José I. Ibeas
PLoS Pathogens, 2015, 11 (8), pp.e1005134. ⟨10.1371/journal.ppat.1005134⟩
Article dans une revue hal-01883467v1
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The Hsp90 cochaperone TTT promotes cotranslational maturation of PIKKs prior to complex assembly

Damien Toullec , Alberto Elías-Villalobos , Céline Faux , Ambre Noly , Gwendaline Lledo , et al.
Article dans une revue hal-03387940v1

Both normal and polyglutamine- expanded ataxin-7 are comp- onents of TFTC-type GCN5 histone acetyltransferase- containing complexes

Dominique Helmlinger , Sara Hardy , Adrien Eberlin , Didier Devys , Làszlo Tora
Biochemical Society Symposia, 2006, 73, pp.155 - 163. ⟨10.1042/bss0730155⟩
Article dans une revue hal-02990344v1
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Hsp70 and Hsp40 Chaperones Do Not Modulate Retinal Phenotype in SCA7 Mice

Dominique Helmlinger , Jacques Bonnet , Jean-Louis Mandel , Yvon Trottier , Didier Devys
Journal of Biological Chemistry, 2004, 279 (53), pp.55969-55977. ⟨10.1074/jbc.m409062200⟩
Article dans une revue hal-02371881v1
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The structure of the NuA4–Tip60 complex reveals the mechanism and importance of long-range chromatin modification

Alexander Fréchard , Céline Faux , Rozalie Hexnerova , Corinne Crucifix , Gabor Papai , et al.
Nature Structural and Molecular Biology, 2023, 30 (9), pp.1337 - 1345. ⟨10.1038/s41594-023-01056-x⟩
Article dans une revue hal-04236230v1
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The HSP90/R2TP assembly chaperone promotes cell proliferation in the intestinal epithelium

Chloé Maurizy , Claire Abeza , Bénédicte Lemmers , Monica Gabola , Ciro Longobardi , et al.
Nature Communications, 2021, 12 (1), pp.4810. ⟨10.1038/s41467-021-24792-4⟩
Article dans une revue hal-03322354v1

Role of chromatin alterations in neurodegeneration induced by polyglutamine-expanded ataxin-7

Dominique Helmlinger , László Tora , Didier Devys
Médecine/Sciences, 2006, 22 (8-9), pp.700-702. ⟨10.1051/medsci/20062289700⟩
Article dans une revue hal-02371873v1

Polyglutamine expansion causes neurodegeneration by altering the neuronal differentiation program

Gretta Abou-Sleymane , Frédéric Chalmel , Dominique Helmlinger , Aurélie Lardenois , Christelle Thibault , et al.
Human Molecular Genetics, 2006, 15 (5), pp.691-703. ⟨10.1093/hmg/ddi483⟩
Article dans une revue hal-02371870v1
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Tra1 has specific regulatory roles, rather than global functions, within the SAGA co-activator complex

Dominique Helmlinger , Samuel Marguerat , Judit Villén , Danielle Swaney , Steven Gygi , et al.
EMBO Journal, 2011, 30 (14), pp.2843-2852. ⟨10.1038/emboj.2011.181⟩
Article dans une revue hal-02371837v1
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La SAGA TOR au secours des levures carencées en nutriments

Thomas Laboucarié , Dominique Helmlinger
Médecine/Sciences, 2018, 34 (8-9), pp.645-648. ⟨10.1051/medsci/20183408005⟩
Article dans une revue hal-02371969v1
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SUPT3H-less SAGA coactivator can assemble and function without significantly perturbing RNA polymerase II transcription in mammalian cells

Veronique Fischer , Vincent Hisler , Elisabeth Scheer , Elisabeth Lata , Bastien Morlet , et al.
Nucleic Acids Research, 2022, pp.gkac637. ⟨10.1093/nar/gkac637⟩
Article dans une revue inserm-03741582v1

New insights into the SAGA complex from studies of the Tra1 subunit in budding and fission yeast.

Dominique Helmlinger
Transcription, 2012, 3 (1), pp.13-8. ⟨10.4161/trns.3.1.19271⟩
Article dans une revue hal-00714804v1
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Retinal cell type expression specificity of HIV-1-derived gene transfer vectors upon subretinal injection in the adult rat: influence of pseudotyping and promoter.

Alexis-Pierre Bemelmans , Sébastien Bonnel , Leila Houhou , Noëlle Dufour , Emeline Nandrot , et al.
The Journal of Gene Medicine, 2005, 7 (10), pp.1367-1374. ⟨10.1002/jgm.788⟩
Article dans une revue hal-00187439v1

Transcriptional alterations and chromatin remodeling in polyglutamine diseases.

Dominique Helmlinger , Làszlò Tora , Didier Devys
Trends in Genetics, 2006, 22 (10), pp.562-70. ⟨10.1016/j.tig.2006.07.010⟩
Article dans une revue istex hal-00187954v1
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The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8

Dominique Helmlinger , S. Marguerat , J. Villén , S. Gygi , J. Bahler , et al.
Genes and Development, 2008, 22 (22), pp.3184-3195. ⟨10.1101/gad.1719908⟩
Article dans une revue hal-02371840v1
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New insights into the evolutionary conservation of the sole PIKK pseudokinase Tra1/TRRAP

Alberto Elías-Villalobos , Philippe Fort , Dominique Helmlinger
Biochemical Society Transactions, 2019, 47 (6), pp.1597 - 1608. ⟨10.1042/BST20180496⟩
Article dans une revue hal-02394910v1
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What do the structures of GCN5-containing complexes teach us about their function?

Dominique Helmlinger , Gábor Papai , Didier Devys , Làszlo Tora
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms , 2020, pp.194614. ⟨10.1016/j.bbagrm.2020.194614⟩
Article dans une revue hal-02990243v2
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Polyglutamine Expansion Induces a Protein-damaging Stress Connecting Heat Shock Protein 70 to the JNK Pathway

Karine Mérienne , Dominique Helmlinger , Gordon Perkin , Didier Devys , Yvon Trottier
Journal of Biological Chemistry, 2003, 278 (19), pp.16957-16967. ⟨10.1074/jbc.m212049200⟩
Article dans une revue hal-02371890v1

Role of chromatin alterations in neurodegeneration induced by polyglutamine-expanded ataxin-7

Dominique Helmlinger , Làszlò Tora , Didier Devys
Médecine/Sciences, 2006, 22 (8-9), pp.700-2
Article dans une revue hal-00187952v1
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Histone deacetylases: revealing the molecular base of dimorphism in pathogenic fungi

Alberto Elias-Villalobos , Dominique Helmlinger , Jose Ibeas
Microbial Cell , 2015, 2 (12), pp.491-493. ⟨10.15698/mic2015.11.240⟩
Article dans une revue hal-02371830v1
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Quantitative analysis of protein-RNA interactions in fission yeast

Alberto Elías-Villalobos , Caia Duncan , Juan Mata , Dominique Helmlinger
STAR Protocols, 2022, 3 (2), pp.101373. ⟨10.1016/j.xpro.2022.101373⟩
Article dans une revue hal-03806582v1
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The TRRAP transcription cofactor represses interferon-stimulated genes in colorectal cancer cells

Dylane Detilleux , Peggy Raynaud , Bérengère Pradet-Balade , Dominique Helmlinger
Article dans une revue hal-03387959v1
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The SAGA histone acetyltransferase module targets SMC5/6 to specific genes

L. Mahrik , B. Stefanovie , A. Maresova , J. Princova , P. Kolesar , et al.
Epigenetics & Chromatin, 2023, 16 (1), pp.6. ⟨10.1186/s13072-023-00480-z⟩
Article dans une revue hal-04236229v1
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Sharing the SAGA

Dominique Helmlinger , László Tora
Trends in Biochemical Sciences, 2017, 42 (11), pp.850--861. ⟨10.1016/j.tibs.2017.09.001⟩
Article dans une revue hal-01875259v1
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Chaperone-mediated ordered assembly of the SAGA and NuA4 transcription co-activator complexes in yeast

Alberto Elías-Villalobos , Damien Toullec , Céline Faux , Martial Séveno , Dominique Helmlinger
Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-13243-w⟩
Article dans une revue hal-02394906v1
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Glutamine-Expanded Ataxin-7 Alters TFTC/STAGA Recruitment and Chromatin Structure Leading to Photoreceptor Dysfunction

Dominique Helmlinger , Sara Hardy , Gretta Abou-Sleymane , Adrien Eberlin , Aaron Bowman , et al.
PLoS Biology, 2006, 4 (3), pp.e67. ⟨10.1371/journal.pbio.0040067⟩
Article dans une revue hal-02371867v1