Recherche - Archive ouverte HAL Accéder directement au contenu

Filtrer vos résultats

50 résultats
Page :
triés par
Image document

Nanoparticles with high payloads of pipemidic acid, a poorly soluble crystalline drug: drug-initiated polymerization and self-assembly approach

 Elisabetta Pancani , Mario Menendez-Miranda , Alexandra Pastor , Francois Brisset , Marie-Francoise Bernet-Camard , et al.
Acta Pharmaceutica Sinica B, 2018, 8 (3), pp.420-431. ⟨10.1016/j.apsb.2018.03.008⟩
Article dans une revue hal-04353113v1
Image document

Squalenoyl siRNA PMP22 nanoparticles are effective in treating mouse models of Charcot-Marie-Tooth disease type 1 A

 Suzan Boutary , Marie Caillaud , Mévidette El Madani , Jean-Michel Vallat , Julien Loisel-Duwattez , et al.
Communications Biology, 2021, 4 (1), pp.317. ⟨10.1038/s42003-021-01839-2⟩
Article dans une revue hal-03189470v1
Image document

Design of Rhenium Compounds in Targeted Anticancer Therapeutics

 Philippe Collery , Didier Desmaele , Vijaykumar Veena
Current Pharmaceutical Design, 2019, 25, pp.3306 - 3322. ⟨10.2174/1381612825666190902161400⟩
Article dans une revue hal-03009702v1
Image document

Antitumor activity of a rhenium (I)-diselenoether complex in experimental models of human breast cancer

 Philippe Collery , Ahmed Mohsen , Anthony Kermagoret , Samantha Corre , Gérard Bastian , et al.
Investigational New Drugs, 2015, Investigational New Drugs, 33 (4), pp.848-860. ⟨10.1007/s10637-015-0265-z⟩
Article dans une revue hal-01346417v1

Preactivated Oxazaphosphorines Designed for Isophosphoramide Mustard Delivery as Bulk Form or Nanoassemblies: Synthesis and Proof of Concept

 Charles Skarbek , Lea Lesueur , Hubert Chapuis , Alain Deroussent , Catherine Pioche−durieu , et al.
Journal of Medicinal Chemistry, 2014, 58 (2), pp.705-717. ⟨10.1021/jm501224x⟩
Article dans une revue hal-03065160v1
Image document

Highly Porous Hybrid Metal–Organic Nanoparticles Loaded with Gemcitabine Monophosphate: a Multimodal Approach to Improve Chemo‐ and Radiotherapy

 Xue Li , Erika Porcel , Mario Menendez‐miranda , Jingwen Qiu , Xiaomin Yang , et al.
ChemMedChem, 2019, 15 (3), pp.274 - 283. ⟨10.1002/cmdc.201900596⟩
Article dans une revue hal-03007090v1

Combined strategy based on pre-activated analogs of oxazaphosphorines for increased therapeutic index and immune modulation

 Julia Delahousse , Charles Skarbek , Valentine Gauthier , Mélanie Desbois , Emilie Roger , et al.
AACR Annual Meeting 2017, 2017, Washington, United States. ⟨10.1158/1538-7445.AM2017-2195⟩
Communication dans un congrès hal-02615988v1

Dual controlled delivery of squalenoyl-gemcitabine and paclitaxel using thermo-responsive polymeric micelles for pancreatic cancer

 Mandana Emamzadeh , Didier Desmaele , Patrick Couvreur , George Pasparakis
Journal of materials chemistry‎ B, 2018, 6 (15), pp.2230-2239. ⟨10.1039/C7TB02899G⟩
Article dans une revue hal-02349752v1
Image document

Albumin-driven disassembly of lipidic nanoparticles: the specific case of the squalene-adenosine nanodrug

 Frédéric Gobeaux , Joëlle Bizeau , Firmin Samson , Laurent Marichal , Isabelle Grillo , et al.
Nanoscale, 2020, 12, pp.2793-2809. ⟨10.1039/C9NR06485K⟩
Article dans une revue cea-02434394v1

Synthesis, structural characterization and biological activity against several human tumor cell lines of four rhenium(I) diseleno-ethers complexes: Re(CO)3Cl(PhSe(CH2)2SePh), Re(CO)3Cl(PhSe(CH2)3SePh), Re(CO)3Cl(HO2C–CH2Se(CH2)2SeCH2–CO2H) and Re(CO)3Cl(HO2C–CH2Se(CH2)3SeCH2–CO2H)

 Anthony Kermagoret , Georges Morgant , Jean D’angelo , Alain Tomas , Pascal Roussel , et al.
Polyhedron, 2011, 30 (2), pp.347-353. ⟨10.1016/j.poly.2010.10.026⟩
Article dans une revue istex hal-02269377v1
Image document

In Vivo FRET Imaging to Predict the Risk Associated with Hepatic Accumulation of Squalene-Based Prodrug Nanoparticles.

 Fanny Cayre , Simona Mura , Bohdan Andreiuk , Dunja Sobot , Sandrine Gouazou , et al.
Advanced healthcare materials, 2017, 7 (3), pp.1700830. ⟨10.1002/adhm.201700830⟩
Article dans une revue hal-02347607v1

New Formulation for the Delivery of Oligonucleotides Using “Clickable” siRNA-Polyisoprenoid-Conjugated Nanoparticles: Application to Cancers Harboring Fusion Oncogenes

 Liliane Massaad-Massade , Suzan Boutary , Marie Caillaud , Céline Gracia , Beatrice Parola , et al.
Bioconjugate Chemistry, 2018, 29 (6), pp.1961-1972. ⟨10.1021/acs.bioconjchem.8b00205⟩
Article dans une revue hal-02349758v1
Image document

New Nanoparticle Formulation for Cyclosporin A: In Vitro Assessment

 Amandine Gendron , Natalie Lan Linh Tran , Julie Laloy , Romain Brusini , Aurélie Rachet , et al.
Pharmaceutics, 2021, 13 (1), pp.91. ⟨10.3390/pharmaceutics13010091⟩
Article dans une revue cea-03119866v1

Photo-physics study of a styrylquinoline as inhibitor of Pim-1 kinase: Solvent and concentration effects

 Taibi Lamhasni , Sara Barbache , Saadia Ait Lyazidi , Mustapha Haddad , Mohamed Hnach , et al.
Chemical Physics Letters, 2018, 695, pp.59-62. ⟨10.1016/j.cplett.2018.02.004⟩
Article dans une revue hal-02347663v1

Styrylquinolines, integrase inhibitors acting prior to integration: a new mechanism of action for anti-integrase agents.

 Sabine Bonnenfant , Claire Marie Thomas , Claudio Vita , Frédéric Subra , Eric Deprez , et al.
Journal of Virology, 2004, 78 (11), pp.5728-36. ⟨10.1128/JVI.78.11.5728-5736.2004⟩
Article dans une revue hal-00282619v1
Image document

Inhibition of in vitro Ebola infection by anti-parasitic quinoline derivatives

 Shawn Goyal , Beth Binnington , Stephen D S Mccarthy , Didier Desmaele , Laurent Ferrié , et al.
F1000Research, 2020, 9, pp.268. ⟨10.12688/f1000research.22352.1⟩
Article dans une revue hal-03009691v1
Image document

Comb-like dextran copolymers: A versatile strategy to coat highly porous MOF nanoparticles with a PEG shell

 Giovanna Cutrone , Jingwen Qiu , Mario Menendez-Miranda , Juan M Casas-Solvas , Ahmet Aykaç , et al.
Carbohydrate Polymers, 2019, 223, pp.115085. ⟨10.1016/j.carbpol.2019.115085⟩
Article dans une revue hal-03009705v1

A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of Human Respiratory Syncytial Virus

 Mohamed Ouizougun-Oubari , Nelson Pereira , Bogdan Tarus , Marie Galloux , Safa Lassoued , et al.
Journal of Virology, 2015, 89 (21), pp.11129-11143. ⟨10.1128/JVI.01612-15⟩
Article dans une revue pasteur-02546455v1
Image document

Conjugation of squalene to gemcitabine as unique approach exploiting endogenous lipoproteins for drug delivery

 Dunja Sobot , Simona Mura , Semen O. Yesylevskyy , Laura Dalbin , Fanny Cayre , et al.
Nature Communications, 2017, 8, ⟨10.1038/ncomms15678⟩
Article dans une revue hal-01666114v1
Image document

A Self-Assembling NHC-Pd-Loaded Calixarene as a Potent Catalyst for the Suzuki-Miyaura Cross-Coupling Reaction in Water

 Arnaud Peramo , Ibrahim Abdellah , Shannon Pecnard , Julie Mougin , Cyril Martini , et al.
Molecules, 2020, 25 (6), pp.1459. ⟨10.3390/molecules25061459⟩
Article dans une revue hal-03009690v1
Image document

Gemcitabine Lipid Prodrugs: The Key Role of the Lipid Moiety on the Self-Assembly into Nanoparticles

 Eleonore Coppens , Didier Desmaele , Julie Mougin , Sandrine Tusseau-Nenez , Patrick Couvreur , et al.
Bioconjugate Chemistry, In press, 32 (4), pp.782-793. ⟨10.1021/acs.bioconjchem.1c00051⟩
Article dans une revue hal-03189242v1
Image document

Synthesis and Biopharmaceutical Characterization of Amphiphilic Squalenyl Derivative Based Versatile Drug Delivery Platform

 Duy-Khiet Ho , Rebekka Christmann , Xabier Murgia , Chiara de Rossi , Sarah Frisch , et al.
Frontiers in Chemistry, 2020, 8, ⟨10.3389/fchem.2020.584242⟩
Article dans une revue hal-03009739v1

A new gallium complex inhibits tumor cell invasion and matrix metalloproteinase MMP-14 expression and activity

 Ahmed Mohsen , Philippe Collery , Roselyne Garnotel , Bertrand Brassart , Nicolas Etique , et al.
Metallomics, 2017, 9 (8), pp.1176-1184. ⟨10.1039/c7mt00049a⟩
Article dans une revue hal-02929237v1
Image document

The fate of squalene-based nanoparticles in biological medium: interactions with serum albumin

 Joëlle Bizeau , Frédéric Gobeaux , Jean-Philippe Renault , Laurent Marichal , Patrick P. Guenoun , et al.
International Conference On Nanomedicine And Nanobiotechnology (ICONAN 2018), Sep 2018, Rome, Italy
Communication dans un congrès cea-02327951v1

Squalene based nanocomposites: a new platform for the design of multifunctional pharmaceutical theragnostics.

 José L Arias , L Harivardhan Reddy , Mohammad Othman , Brigitte Gillet , Didier Desmaële , et al.
ACS Nano, 2011, 5 (2), pp.1513-21. ⟨10.1021/nn1034197⟩
Article dans une revue hal-00589109v1
Image document

Quantification of drug loading in polymeric nanoparticles using AFM-IR technique: a novel method to map and evaluate drug distribution in drug nanocarriers

 M. Seray Ural , Emmanuel Dartois , Jérémie Mathurin , Didier Desmaële , Philippe Collery , et al.
Analyst, 2022, 147 (23), pp.5564-5578. ⟨10.1039/D2AN01079H⟩
Article dans une revue hal-03850497v1
Image document

Effects of siRNA on RET/PTC3 Junction Oncogene in Papillary Thyroid Carcinoma: From Molecular and Cellular Studies to Preclinical Investigations

 Hafiz Muhammad Ali , Giorgia Urbinati , Hubert Chapuis , Didier Desmaële , Jean-Rémi Bertrand , et al.
PLoS ONE, 2014, 9 (4), pp.e95964. ⟨10.1371/journal.pone.0095964⟩
Article dans une revue hal-02329832v1

Electrostatic properties of two precursors of potent HIV-1 integrase inhibitors

 Delphine Firley , Blandine Courcot , Jean-Michel Gillet , Anne Spasojevic - de Biré , Bernard Fraisse , et al.
XX IUCR, Aug 2005, Florence, Italy. pp.c277 c277, ⟨10.1107/S0108767305088203⟩
Communication dans un congrès hal-02304690v1
Image document

Selective modification of a native protein in a patient tissue homogenate using palladium nanoparticles

 Arnaud Peramo , Anaëlle Dumas , Hynd Remita , Mireille Benoît , Stephanie Yen-Nicolay , et al.
Chemical Communications, 2019, 55, pp.15121 - 15124. ⟨10.1039/c9cc07803g⟩
Article dans une revue hal-03009700v1

Lipid Conjugated Oligonucleotides: A Useful Strategy for Delivery

 Mouna Raouane , Didier Desmaële , Giorgia Urbinati , Liliane Massaad-Massade , Patrick Couvreur
Bioconjugate Chemistry, 2012, 23 (6), pp.1091-1104. ⟨10.1021/bc200422w⟩
Article dans une revue hal-02330037v1
Page :