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2-Aminothiazole-Flavonoid Hybrid Derivatives Binding to Tau Protein and Responsible for Antitumor Activity in Glioblastoma

Rayane Hedna , Attilio Dimaio , Maxime Robin , Diane Allegro , Mario Tatoni , et al.
International Journal of Molecular Sciences, 2023, 24 (20), pp.15050. ⟨10.3390/ijms242015050⟩
Article dans une revue hal-04281487v1

Synthesis and biological evaluation of novel anticancer bivalent colchicine–tubulizine hybrids

Yulia Malysheva , Sébastien Combes , Diane Allegro , Vincent Peyrot , Paul Knochel , et al.
Bioorganic and Medicinal Chemistry, 2012, 20 (14), pp.4271 - 4278. ⟨10.1016/j.bmc.2012.05.072⟩
Article dans une revue istex hal-01749009v1

Synthesis and biological evaluation of 4 arylcoumarin analogues as tubulin-targeting antitumor agents

Peggoty Mutai , Gilles Breuzard , Alessandra Pagano , Diane Allegro , Vincent Peyrot , et al.
Bioorganic and Medicinal Chemistry, 2017, 25 (5), pp.1652 - 1665. ⟨10.1016/j.bmc.2017.01.035⟩
Article dans une revue hal-01744155v1

Caulerpenyne binding to tubulin: structural modifications by a non conventional pharmacological agent.

Julien Bourdron , Pascale Barbier , Diane Allegro , Claude Villard , Daniel Lafitte , et al.
Medicinal Chemistry, 2009, 5 (2), pp.182-90
Article dans une revue hal-00678950v1

Synthesis and Biological Evaluation of Furanoallocolchicinoids

Yuliya Voitovich , Ekaterina Shegravina , Nikolay Sitnikov , Vladimir Faerman , Valery Fokin , et al.
Journal of Medicinal Chemistry, 2014, 58 (2), pp.692 - 704. ⟨10.1021/jm501678w⟩
Article dans une revue hal-01744566v1
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Quantitative Analysis of Tau-Microtubule Interaction Using FRET

Isabelle L. Di Maio , Pascale Barbier , Diane Allegro , Cédric Brault , Vincent Peyrot
International Journal of Molecular Sciences, 2014, 15 (8), pp.14697-14714. ⟨10.3390/ijms150814697⟩
Article dans une revue hal-01314628v1
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Two Tau binding sites on tubulin revealed by thiol-disulfide exchanges

Marlène Martinho , Diane Allegro , Isabelle Huvent , Charlotte Chabaud , Emilien Etienne , et al.
Scientific Reports, 2018, 8 (1), pp.13846. ⟨10.1038/s41598-018-32096-9⟩
Article dans une revue hal-01883844v1
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Tau Interaction with Tubulin and Microtubules: From Purified Proteins to Cells

Tiphany de Bessa , Gilles Breuzard , Diane Allegro , François Devred , Vincent Peyrot , et al.
Tau Protein, 1523, pp.61-85, 2017, ⟨10.1007/978-1-4939-6598-4_4⟩
Chapitre d'ouvrage hal-01744157v2

Hsp90 Oligomerization Process: How Can p23 Drive the Chaperone Machineries?

Eléonore Lepvrier , Michaël Nigen , Laura Moullintraffort , Sophie Chat , Diane Allegro , et al.
Biochimica et Biophysica Acta Proteins and Proteomics, 2015, 1854 (10), pp.1412-1424. ⟨10.1016/j.bbapap.2015.07.003⟩
Article dans une revue hal-01174219v1
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Modulation of microtubule assembly by the HIV-1 Tat protein is strongly dependent on zinc binding to Tat.

Caroline Egelé , Pascale Barbier , Pascal Didier , Etienne Piémont , Diane Allegro , et al.
Retrovirology, 2008, 5, pp.62. ⟨10.1186/1742-4690-5-62⟩
Article dans une revue hal-00321631v1

Allocolchicinoids bearing a Michael acceptor fragment for possible irreversible binding of tubulin

Ekaterina Sazanova , Iuliia Gracheva , Diane Allegro , Pascale Barbier , Sébastien Combes , et al.
RSC Medicinal Chemistry, 2020, 11 (6), pp.696-706. ⟨10.1039/D0MD00060D⟩
Article dans une revue hal-02997624v1

Hsp90 Oligomers Interacting with the Aha1 Cochaperone: An Outlook for the Hsp90 Chaperone Machineries

Eléonore Lepvrier , Laura Moullintraffort , Michaël Nigen , Renan Goude , Diane Allegro , et al.
Analytical Chemistry, 2015, 87 (14), pp.7043-7051. ⟨10.1021/acs.analchem.5b00051⟩
Article dans une revue hal-01175535v1

Discovery of a new family of bis-8-hydroxyquinoline substituted benzylamines with pro-apoptotic activity in cancer cells: Synthesis, structure-activity relationship, and action mechanism studies.

Vincent Moret , Younes Laras , Thierry Cresteil , Geneviève Aubert , Dou Q Ping , et al.
European Journal of Medicinal Chemistry, 2008, 44 (2), pp.558-557. ⟨10.1016/j.ejmech.2008.03.042⟩
Article dans une revue istex hal-00294478v1
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Identification of the three zinc-binding sites on tau protein

Romain Rocca , Philipp O Tsvetkov , Andrey Golovin , Diane Allegro , Pascale Barbier , et al.
International Journal of Biological Macromolecules, 2022, 209, pp.779-784. ⟨10.1016/j.ijbiomac.2022.04.058⟩
Article dans une revue hal-03647684v1

Interactions of long-chain homologues of colchicine with tubulin

Ana Marzo-Mas , Pascale Barbier , Gilles Breuzard , Diane Allegro , Eva Falomir , et al.
European Journal of Medicinal Chemistry, 2017, 126, pp.526 - 535. ⟨10.1016/j.ejmech.2016.11.049⟩
Article dans une revue hal-01744468v1
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Stathmin/Op18 is a novel mediator of vinblastine activity

François Devred , Philipp O Tsvetkov , Pascale Barbier , Diane Allegro , Susan Band Horwitz , et al.
FEBS Letters, 2008, 582 (17), pp.2484 - 2488. ⟨10.1016/j.febslet.2008.06.035⟩
Article dans une revue hal-01756897v1
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Modulation of microtubule assembly by the HIV-1 Tat protein is strongly dependent on zinc binding to Tat

Caroline Egelé , Pascal Barbier , Pascal Didier , Etienne Piémont , Diane Allegro , et al.
Retrovirology, 2008, 5, pp.62. ⟨10.1186/1742-4690-5-62⟩
Article dans une revue hal-01480684v1

Biochemical and biophysical characterization of the Mg2+-induced 90-kDa heat shock protein oligomers.

Laura Moullintraffort , Matthieu Bruneaux , Alexis Nazabal , Diane Allegro , Emmanuel Giudice , et al.
Journal of Biological Chemistry, 2010, 285 (20), pp.15100-10. ⟨10.1074/jbc.M109.094698⟩
Article dans une revue hal-00485599v1

Discovery of dihydrofuranoallocolchicinoids - Highly potent antimitotic agents with low acute toxicity

Ekaterina S. Shchegravina , Elena V. Svirshchevskaya , Sebastien Combes , Diane Allegro , Pascale Barbier , et al.
European Journal of Medicinal Chemistry, 2020, 207, pp.112724. ⟨10.1016/j.ejmech.2020.112724⟩
Article dans une revue hal-02928157v1