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Mambalgins, snake peptides against inflammatory and neuropathic pain through inhibition of ASIC channels

Anne Baron , Sylvie Diochot , Miguel Salinas , Abdelkrim Alloui , Dominique Douguet , et al.
SFET Société Française d'Etude des Toxines, Dec 2016, Paris, France. pp.93, ⟨10.1016/j.toxicon.2017.12.026⟩
Communication dans un congrès hal-02355724v1

The marine phycotoxin gymnodimine targets muscular and neuronal nicotinic acetylcholine receptor subtypes with high affinity.

Riadh Kharrat , Denis Servent , Emmanuelle Girard , Gilles Ouanounou , Muriel Amar , et al.
Journal of Neurochemistry, 2008, 107 (4), pp.952-63. ⟨10.1111/j.1471-4159.2008.05677.x⟩
Article dans une revue hal-00316051v1

Cyclic imine toxins: From shellfish poisoning to neuroscience: The case of acyl derivatives

Rómulo Aráoz , Philipp Hess , Franck Pélissier , Evelyne Benoit , Denis Servent , et al.
5th nAChR satellite symposium on « Nicotinic Acetylcholine Receptors as Therapeutic Targets: Emerging Frontiers in Basic Research & Clinical Science », Oct 2015, Chicago, United States. pp.622, ⟨10.1016/j.bcp.2015.08.007⟩
Communication dans un congrès hal-02334385v1
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A multiscale functional approach to appraise the pharmacological interactions between spider venom peptides and Nav1.7, a genetically validated analgesic target

Tânia C. Gonçalves , Michel Partiseti , Denis Servent , Evelyne Benoit
YRLS 2018 - 9th Young Researchers in Life Science, May 2018, Paris, France.
Poster de conférence hal-04466900v1
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Evidence of rattlesnake crotalphin effects on tetrodotoxin-sensitive Na channels of mouse dorsal root ganglion neurons

Aurélie Antunes , Philippe Robin , Gilles Mourier , Michel de Waard , Rémy Béroud , et al.
RT28 – 28th Meeting of the French Society of Toxinology – Toxins: What’s up, Doc?, Nov 2022, Paris, France
Poster de conférence hal-04472728v1
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Gambierol Potently Increases Evoked Quantal Transmitter Release and Reverses Pre- and Post-Synaptic Blockade at Vertebrate Neuromuscular Junctions

Jordi Molgó , Sébastien Schlumberger , Makoto Sasaki , Haruhiko Fuwa , Carmen M. Louzao , et al.
Neuroscience, 2020, 439, pp.106-116. ⟨10.1016/j.neuroscience.2019.06.024⟩
Article dans une revue hal-02324830v1

Pinnatoxins, an emergent class of marine toxins interacting with nAChRs. Pharmacological characterization, biodistribution and musculo-skeletal effect of these neurotoxic agents

Denis Servent , Sophie Creuzet , Carole Malgorn , Vincent Dive , Armen Zakarian , et al.
Toxicon, 2020, 177 (Suppl 1), pp.S3. ⟨10.1016/j.toxicon.2019.10.015⟩
Article dans une revue hal-02912939v1
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Antinociceptive targets for spider toxins in adult dorsal root ganglia neurons

Tânia C. Gonçalves , Evelyne Benoit , Michel Partiseti , Denis Servent
RT25 - 25th Meeting of the French Society of Toxinology – Toxins and Health: From Molecules to Organisms, Nov 2018, Paris, France.
Poster de conférence hal-04467180v1
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Toxins and Ion transfers

Julien Barbier , Evelyne Benoit , Nicolas Gilles , Daniel Ladant , Marie-France Martin-Eauclaire , et al.
SFET Publications, Gif-sur-Yvette, France, pp.123, 2011
Ouvrages hal-00738632v1
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Toxins and Signalling

Evelyne Benoit , Françoise Goudey-Perriere , Pascale Marchot , Denis Servent
SFET Publications, Châtenay-Malabry, France, pp.204, 2009
Ouvrages hal-00738643v1
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A snake toxin as a theranostic agent for the type 2 vasopressin receptor

Laura Droctové , Manon Lancien , Vu Long Tran , Michaël Susset , Benoit Jego , et al.
Theranostics, 2020, 10 (25), pp.11580-11594. ⟨10.7150/thno.47485⟩
Article dans une revue hal-02960704v1
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Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal α7 from Muscle α12βγδ nAChRs.

Yves Bourne , Gerlind Sulzenbacher , Zoran Radić , Rómulo Aráoz , Morgane Reynaud , et al.
Structure (London, England : 1993), 2015, 23 (6), pp.1106-15. ⟨10.1016/j.str.2015.04.009⟩
Article dans une revue hal-01178822v1

Study on the affinity and selectivity improvement of the spider phlotoxin 1 for the human 1.7 subtype of voltage-gated sodium channels

Evelyne Benoit , Tânia C. Gonçalves , Pierre Lesport , Sarah Kuylle , Enrico Stura , et al.
RT26 – 26th Meeting of the French Society of Toxinology – Bioengineering of Toxins, Dec 2019, Paris, France
Poster de conférence hal-04469856v1
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Multi−scale evaluation of spider toxins as potential anti−nociceptive agents: example of Cyriotoxin−1a

Evelyne Benoit , Michel de Waard , Rémy Béroud , Michel Partiseti , Denis Servent
EUVEN 2021 - 1st International Congress of the European Venom Network, Sep 2021, Saint-Josse-Ten-Noode (Virtual), Belgium.
Poster de conférence hal-04470153v1
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Venoms in drug discovery: a case study on voltage-gated channels

Jean-Marie Chambard , Tânia C. Gonçalves , Evelyne Benoit , Rachid Boukaiba , Michael Kurtz , et al.
RT25 - 25th Meeting of the French Society of Toxinology – Toxins and Health: From Molecules to Organisms, French Society of Toxinology (SFET), Nov 2018, Paris, France
Communication dans un congrès hal-04464835v1
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Venom peptides: promising tools for lung cancer imaging

Romain Baudat , Evelyne Benoit , Mathilde Keck , Pascal Kessler , Charles Truillet , et al.
Journées scientifiques croisées des programmes Focus Organoïdes sur Puce et Focus Biomarqueurs, Oct 2023, Gif-sur-Yvette, France
Poster de conférence hal-04474222v1
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In vivo and in vitro pinnatoxins A and G reversibly block transmission at the skeletal neuromuscular junction

Evelyne Benoit , Aurélie Couesnon , Jiri Lindovsky , Bogdan Iorga , Armen Zakarian , et al.
PHYCOTOX 2019 - GDR Annual Conference on Toxic Microalgae, May 2019, Plouzané, France.
Poster de conférence hal-04467214v1

The three-finger toxin fold: a multifunctional structural scaffold able to modulate cholinergic functions

Pascal Kessler , Pascale Marchot , Marcela Silva , Denis Servent
Journal of Neurochemistry, 2017, 142, pp.7 - 18. ⟨10.1111/jnc.13975⟩
Article dans une revue hal-01802811v1

Diversity in the binding interactions of marine phycotoxins to AChBP, the soluble nAChR surrogate

Pascale Marchot , Gerlind Sulzenbacher , Zoran Radic , Rómulo Aráoz , Emmanuelle Reynaud , et al.
XVth International Symposium on Cholinergic Mechanisms, Oct 2017, Marseille, France. pp.196, ⟨10.1111/jnc.13925⟩
Communication dans un congrès hal-02334376v1

Green mamba peptide targets type-2 vasopressin receptor against polycystic kidney disease

Justyna Ciolek , Helen Reinfrank , Loïc Quinton , Say Viengchareun , Enrico A. Stura , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (27), pp.7154-7159. ⟨10.1073/pnas.1620454114⟩
Article dans une revue hal-02050051v1

Pinnatoxins: an emergent family of marine phycotoxins targeting nicotinic acetylcholine receptors with high affinity

Rómulo Aráoz , Denis Servent , Jordi Molgo , Bogdan Iorga , C. Fruchard-Gaillard , et al.
J. Barbier, E. Benoit, N. Gilles, D. Ladant, M.-F. Martin-Eauclaire, C. Mattéi, J. Molgó, M.R. Poppof & D. Servent. Toxins and Ion transfers, SFET Publications, pp.43-47, 2011, Collection Rencontres en Toxinologie, 1760-6004
Chapitre d'ouvrage hal-02334617v1
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Editorial : Special issue on "toxins: from threats to benefits".

Marie-France Martin-Eauclaire , Evelyne Benoit , Pascale Marchot , Julien Barbier , Jordi Molgó , et al.
Toxicon, 2013, 75, pp.1-2. ⟨10.1016/j.toxicon.2013.08.001⟩
Article dans une revue hal-00919888v1
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Mambalgin-1 pain-relieving peptide locks the hinge between α4 and α5 helices to inhibit rat Acid-Sensing Ion Channel 1a

Miguel Salinas , Pascal Kessler , Dominique Douguet , Daad Sarraf , Nicolo Tonali , et al.
Neuropharmacology, 2021, 185, pp.108453. ⟨10.1016/j.neuropharm.2021.108453⟩
Article dans une revue hal-03115234v1
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The Dinoflagellate Toxin 20-Methyl Spirolide-G Potently Blocks Skeletal Muscle and Neuronal Nicotinic Acetylcholine Receptors.

Aurélie Couesnon , Rómulo Aráoz , Bogdan I Iorga , Evelyne Benoit , Morgane Reynaud , et al.
Toxins, 2016, 8 (9), pp.249. ⟨10.3390/toxins8090249⟩
Article dans une revue hal-01443823v1

Toxins: New Targets and New Functions

Jordi Molgó , Evelyne Benoit , Julien Barbier , Michel Popoff , Grazyna Faure , et al.
J. MOLGO, E. BENOIT, J. BARBIER, M.R. POPPOF, G. FAURE & D. SERVENT (Eds). Rencontres en Toxinologie « Toxins: New Targets and New Functions » organisées par la Société Française pour l'Etude des Toxines, Dec 2014, Paris, France. Toxicon, 116, 2016, Special issue of Toxicon, 0041-0101
N°spécial de revue/special issue hal-02334653v1

Functional determinants by which snake and cone snail toxins block the alpha 7 neuronal nicotinic acetylcholine receptors.

Denis Servent , Hung Lam Thanh , Stéphanie Antil , Daniel Bertrand , Pierre-Jean Corringer , et al.
Journal of Physiology - Paris, 1998, 92 (2), pp.107-11. ⟨10.1016/S0928-4257(98)80146-0⟩
Article dans une revue istex pasteur-01718432v1
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Gambierol blocks a K(+) current component affecting action potential duration in fetal adrenomedullary chromaffin cells. Is this action sufficient to modulate catecholamine release?

Jordi Molgó , Roland Bournaud , Sébastien Schlumberger , Makoto Sasaki , Haruhiko Fuwa , et al.
ICHA 2021 - 19th International conference on Harmful algae, Oct 2021, La Paz (Virtual), Mexico
Poster de conférence hal-04471073v2

First evidence that emerging pinnatoxin-G, a contaminant of shellfish, reaches the brain and crosses the placental barrier

Denis Servent , Carole Malgorn , Mylène Bernes , Sophie Gil , Christelle Simasotchi , et al.
Science of the Total Environment, 2021, 790, pp.148125. ⟨10.1016/j.scitotenv.2021.148125⟩
Article dans une revue hal-04456600v1
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A multiscale functional approach to assess pharmacologocal interactions between huwentoxin-IV spider peptide and sodium channel subtypes

Tânia C. Gonçalves , Rachid Boukaiba , Jordi Molgó , Muriel Amar , Michel Partiseti , et al.
23th Meeting on Toxinology « Toxins: Immunity, Inflammation and Pain » organized by the French Society of Toxinology (SFET), Toxicon, 149, pp.105-106, 2018, ⟨10.1016/j.toxicon.2018.02.035⟩
Proceedings/Recueil des communications hal-02334358v1
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Direct evidence for high affinity blockade of Nav1.6 channel subtype by huwentoxin-IV spider peptide, using multiscale functional approaches

Tânia C. Gonçalves , Rachid Boukaiba , Jordi Molgó , Muriel Amar , Michel Partiseti , et al.
Neuropharmacology, 2018, 133, pp.404-414. ⟨10.1016/j.neuropharm.2018.02.016⟩
Article dans une revue hal-01828943v1