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Mambalgins, snake peptides against inflammatory and neuropathic pain through inhibition of ASIC channels

Anne Baron , Sylvie Diochot , Miguel Salinas , Abdelkrim Alloui , Dominique Douguet , et al.
SFET Société Française d'Etude des Toxines, Dec 2016, Paris, France. pp.93, ⟨10.1016/j.toxicon.2017.12.026⟩
Communication dans un congrès hal-02355724v1

The marine phycotoxin gymnodimine targets muscular and neuronal nicotinic acetylcholine receptor subtypes with high affinity.

Riadh Kharrat , Denis Servent , Emmanuelle Girard , Gilles Ouanounou , Muriel Amar , et al.
Journal of Neurochemistry, 2008, 107 (4), pp.952-63. ⟨10.1111/j.1471-4159.2008.05677.x⟩
Article dans une revue hal-00316051v1

Cyclic imine toxins: From shellfish poisoning to neuroscience: The case of acyl derivatives

Rómulo Aráoz , Philipp Hess , Franck Pélissier , Evelyne Benoit , Denis Servent , et al.
5th nAChR satellite symposium on « Nicotinic Acetylcholine Receptors as Therapeutic Targets: Emerging Frontiers in Basic Research & Clinical Science », Oct 2015, Chicago, United States. pp.622, ⟨10.1016/j.bcp.2015.08.007⟩
Communication dans un congrès hal-02334385v1
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A multiscale functional approach to appraise the pharmacological interactions between spider venom peptides and Nav1.7, a genetically validated analgesic target

Tânia C. Gonçalves , Michel Partiseti , Denis Servent , Evelyne Benoit
YRLS 2018 - 9th Young Researchers in Life Science, May 2018, Paris, France.
Poster de conférence hal-04466900v1
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Evidence of rattlesnake crotalphin effects on tetrodotoxin-sensitive Na channels of mouse dorsal root ganglion neurons

Aurélie Antunes , Philippe Robin , Gilles Mourier , Michel de Waard , Rémy Béroud , et al.
RT28 – 28th Meeting of the French Society of Toxinology – Toxins: What’s up, Doc?, Nov 2022, Paris, France
Poster de conférence hal-04472728v1
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Gambierol Potently Increases Evoked Quantal Transmitter Release and Reverses Pre- and Post-Synaptic Blockade at Vertebrate Neuromuscular Junctions

Jordi Molgó , Sébastien Schlumberger , Makoto Sasaki , Haruhiko Fuwa , Carmen M. Louzao , et al.
Neuroscience, 2020, 439, pp.106-116. ⟨10.1016/j.neuroscience.2019.06.024⟩
Article dans une revue hal-02324830v1

Pinnatoxins, an emergent class of marine toxins interacting with nAChRs. Pharmacological characterization, biodistribution and musculo-skeletal effect of these neurotoxic agents

Denis Servent , Sophie Creuzet , Carole Malgorn , Vincent Dive , Armen Zakarian , et al.
Toxicon, 2020, 177 (Suppl 1), pp.S3. ⟨10.1016/j.toxicon.2019.10.015⟩
Article dans une revue hal-02912939v1
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Antinociceptive targets for spider toxins in adult dorsal root ganglia neurons

Tânia C. Gonçalves , Evelyne Benoit , Michel Partiseti , Denis Servent
RT25 - 25th Meeting of the French Society of Toxinology – Toxins and Health: From Molecules to Organisms, Nov 2018, Paris, France.
Poster de conférence hal-04467180v1
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Toxins and Ion transfers

Julien Barbier , Evelyne Benoit , Nicolas Gilles , Daniel Ladant , Marie-France Martin-Eauclaire , et al.
SFET Publications, Gif-sur-Yvette, France, pp.123, 2011
Ouvrages hal-00738632v1
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Toxins and Signalling

Evelyne Benoit , Françoise Goudey-Perriere , Pascale Marchot , Denis Servent
SFET Publications, Châtenay-Malabry, France, pp.204, 2009
Ouvrages hal-00738643v1
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Mambalgin-1 pain-relieving peptide locks the hinge between α4 and α5 helices to inhibit rat Acid-Sensing Ion Channel 1a

Miguel Salinas , Pascal Kessler , Dominique Douguet , Daad Sarraf , Nicolo Tonali , et al.
Neuropharmacology, 2021, 185, pp.108453. ⟨10.1016/j.neuropharm.2021.108453⟩
Article dans une revue hal-03115234v1
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The Dinoflagellate Toxin 20-Methyl Spirolide-G Potently Blocks Skeletal Muscle and Neuronal Nicotinic Acetylcholine Receptors.

Aurélie Couesnon , Rómulo Aráoz , Bogdan I Iorga , Evelyne Benoit , Morgane Reynaud , et al.
Toxins, 2016, 8 (9), pp.249. ⟨10.3390/toxins8090249⟩
Article dans une revue hal-01443823v1

Toxins: New Targets and New Functions

Jordi Molgó , Evelyne Benoit , Julien Barbier , Michel Popoff , Grazyna Faure , et al.
J. MOLGO, E. BENOIT, J. BARBIER, M.R. POPPOF, G. FAURE & D. SERVENT (Eds). Rencontres en Toxinologie « Toxins: New Targets and New Functions » organisées par la Société Française pour l'Etude des Toxines, Dec 2014, Paris, France. Toxicon, 116, 2016, Special issue of Toxicon, 0041-0101
N°spécial de revue/special issue hal-02334653v1

Functional determinants by which snake and cone snail toxins block the alpha 7 neuronal nicotinic acetylcholine receptors.

Denis Servent , Hung Lam Thanh , Stéphanie Antil , Daniel Bertrand , Pierre-Jean Corringer , et al.
Journal of Physiology - Paris, 1998, 92 (2), pp.107-11. ⟨10.1016/S0928-4257(98)80146-0⟩
Article dans une revue istex pasteur-01718432v1
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Gambierol blocks a K(+) current component affecting action potential duration in fetal adrenomedullary chromaffin cells. Is this action sufficient to modulate catecholamine release?

Jordi Molgó , Roland Bournaud , Sébastien Schlumberger , Makoto Sasaki , Haruhiko Fuwa , et al.
ICHA 2021 - 19th International conference on Harmful algae, Oct 2021, La Paz (Virtual), Mexico
Poster de conférence hal-04471073v2

First evidence that emerging pinnatoxin-G, a contaminant of shellfish, reaches the brain and crosses the placental barrier

Denis Servent , Carole Malgorn , Mylène Bernes , Sophie Gil , Christelle Simasotchi , et al.
Science of the Total Environment, 2021, 790, pp.148125. ⟨10.1016/j.scitotenv.2021.148125⟩
Article dans une revue hal-04456600v1
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A multiscale functional approach to assess pharmacologocal interactions between huwentoxin-IV spider peptide and sodium channel subtypes

Tânia C. Gonçalves , Rachid Boukaiba , Jordi Molgó , Muriel Amar , Michel Partiseti , et al.
23th Meeting on Toxinology « Toxins: Immunity, Inflammation and Pain » organized by the French Society of Toxinology (SFET), Toxicon, 149, pp.105-106, 2018, ⟨10.1016/j.toxicon.2018.02.035⟩
Proceedings/Recueil des communications hal-02334358v1
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Direct evidence for high affinity blockade of Nav1.6 channel subtype by huwentoxin-IV spider peptide, using multiscale functional approaches

Tânia C. Gonçalves , Rachid Boukaiba , Jordi Molgó , Muriel Amar , Michel Partiseti , et al.
Neuropharmacology, 2018, 133, pp.404-414. ⟨10.1016/j.neuropharm.2018.02.016⟩
Article dans une revue hal-01828943v1
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3,4-Diaminopyridine antagonizes the block of muscle nicotinic acetylcholine receptor caused by cyclic imine toxins at isolated mouse diaphragm preparations

Nicolas Lamassiaude , Évelyne Benoit , Rómulo Aráoz , Armen Zakarian , Denis Servent , et al.
RT29 – 29th Meeting of the French Society of Toxinology – Toxins: From the Wild to the Lab, Nov 2023, Paris, France
Poster de conférence hal-04474247v1
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Therapeutic potential of venom peptides interacting with GPCRs and ion channels

Nicolas Gilles , Gilles Mourier , Pascal Kessler , Laura Droctové , Tânia C. Gonçalves , et al.
1st International symposium of Paris-Saclay University - Drug Discovery and New Therapeutics, Apr 2018, Orsay, France
Poster de conférence hal-04466366v1
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Gambierol, a marine dinoflagellate toxin, potently increases evoked quantal transmitter release and reverses pre- and post-synaptic neuromuscular block at vertebrate junctions

Jordi Molgó , Sébastien Schlumberger , Haruhiko Fuwa , Evelyne Benoit , Denis Servent
20th World Congress of the International Society on Toxinology - Toxinology in the 21st century: Public health impact from basic, translational and clinical sciences, International Society on Toxinology, Sep 2019, Buenos Aires, Argentina
Communication dans un congrès hal-04465977v1
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The voltage-dependent sodium channel : A well-known molecular target of saxitoxins (cyanotoxins), ciguatoxins and brevetoxins (phycotoxins)

Evelyne Benoit , Denis Servent , Jordi Molgó
PHYCOTOX 2023 - GDR Annual Conference on Toxic Microalgae, May 2023, Nantes, France
Poster de conférence hal-04473937v1

Identification of a novel snake peptide toxin displaying high affinity and antagonist behaviour for the α(2) -adrenoceptors.

Céline Rouget , Loïc Quinton , Arhamatoulaye Maïga , Céline Gales , Geoffrey Masuyer , et al.
British Journal of Pharmacology, 2010, epub ahead of print. ⟨10.1111/j.1476-5381.2010.00966.x⟩
Article dans une revue hal-00528529v1

Characterization of the First Animal Toxin Acting as an Antagonist on AT1 Receptor

Anne-Cécile van Baelen , Xavier Iturrioz , Marion Chaigneau , Pascal Kessler , Catherine Llorens-Cortes , et al.
International Journal of Molecular Sciences, 2023, 24 (3), pp.2330. ⟨10.3390/ijms24032330⟩
Article dans une revue hal-04456586v1

Efficient functional neutralization of lethal peptide toxins in vivo by oligonucleotides

Tarek Mohamed Abd El-Aziz , Corinne Ravelet , Jordi Molgó , Emmanuelle Fiore , Simon Pale , et al.
Scientific Reports, 2017, 7 (1), ⟨10.1038/s41598-017-07554-5⟩
Article dans une revue hal-01639599v1
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Advances and new technologies in Toxinology

Julien Barbier , Evelyne Benoit , Pascale Marchot , César Mattei , Denis Servent
SFET Publications, Gif-sur-Yvette, France, pp.186, 2010
Ouvrages hal-00738636v1

Influence of MT7 toxin on the oligomerization state of the M1 muscarinic receptor.

Catherine Marquer , Carole Fruchart-Gaillard , Gilles Mourier , Olivier Grandjean , Emmanuelle Girard , et al.
Biology of the Cell, 2010, 102 (7), pp.409-20. ⟨10.1042/BC20090171⟩
Article dans une revue hal-00856094v1
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A snake toxin as a theranostic agent for the type 2 vasopressin receptor

Laura Droctové , Manon Lancien , Vu Long Tran , Michaël Susset , Benoit Jego , et al.
Theranostics, 2020, 10 (25), pp.11580-11594. ⟨10.7150/thno.47485⟩
Article dans une revue hal-02960704v1

Green mamba peptide targets type-2 vasopressin receptor against polycystic kidney disease

Justyna Ciolek , Helen Reinfrank , Loïc Quinton , Say Viengchareun , Enrico A. Stura , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (27), pp.7154-7159. ⟨10.1073/pnas.1620454114⟩
Article dans une revue hal-02050051v1
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Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal α7 from Muscle α12βγδ nAChRs.

Yves Bourne , Gerlind Sulzenbacher , Zoran Radić , Rómulo Aráoz , Morgane Reynaud , et al.
Structure (London, England : 1993), 2015, 23 (6), pp.1106-15. ⟨10.1016/j.str.2015.04.009⟩
Article dans une revue hal-01178822v1