Delphyne Descamps

Quentin Marquant, Daphné Laubreton, Carole Drajac, Elliot Mathieu, Edwige Bouguyon, et al.. The microbiota plays a critical role in the reactivity of lung immune components to innate ligands. FASEB Journal, Federation of American Society of Experimental Biology, 2021, 35 (4), 15 p. ⟨10.1096/fj.202002338R⟩. ⟨hal-03169721⟩

Delphyne Descamps, Irini Evnouchidou, Vivien Caillens, Carole Drajac, Sabine Riffault, et al.. The Role of Insulin Regulated Aminopeptidase in Endocytic Trafficking and Receptor Signaling in Immune Cells. Frontiers in Molecular Biosciences, Frontiers Media, 2020, 7, ⟨10.3389/fmolb.2020.583556⟩. ⟨hal-02972353⟩

Daphné Laubreton, Carole Drajac, Jean François Eléou T, Marie Anne Rameix-Welti, Richard Lo-Man, et al.. Regulatory B lymphocytes colonize the respiratory tract of neonatal mice and modulate immune responses of alveolar macrophages to RSV infection in IL-10-dependant manner. Viruses, MDPI, 2020, 12 (8), ⟨10.3390/v12080822⟩. ⟨hal-02938422⟩

Bertrand Bryche, Maxence Fretaud, Audrey Saint‐albin Deliot, Marie Galloux, Laura Sedano, et al.. Respiratory syncytial virus tropism for olfactory sensory neurons in mice. Journal of Neurochemistry, Wiley, 2020, ⟨10.1111/jnc.14936⟩. ⟨hal-02899462⟩

Fabian Sesterhenn, Che Yang, Jaume Bonet, Johannes T. Cramer, Xiaolin Wen, et al.. De novo protein design enables the precise induction of RSV-neutralizing antibodies. Science, American Association for the Advancement of Science (AAAS), 2020, 368 (6492), ⟨10.1126/science.aay5051⟩. ⟨hal-02677103⟩

Fabian Sesterhenn, Marie Galloux, Sabrina Vollers, Lucia Csepregi, Che Yang, et al.. Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen. PLoS Biology, Public Library of Science, 2019, 17 (2), pp.e3000164. ⟨10.1371/journal.pbio.3000164⟩. ⟨inserm-02138858⟩

Cynthia Calzas, Delphyne Descamps, Michel Chignard, Christophe Chevalier. Editorial: Innovative Therapeutic and Vaccine Approaches Against Respiratory Pathogens. Frontiers in Immunology, Frontiers, 2019, 10, ⟨10.3389/fimmu.2019.02960⟩. ⟨hal-02943195⟩

Elliot Mathieu, Unai Escribano-Vazquez, Delphyne Descamps, Claire Cherbuy, Philippe Langella, et al.. Paradigms of Lung Microbiota Functions in Health and Disease, Particularly, in Asthma. Frontiers in Physiology, Frontiers, 2018, 9, pp.1-11. ⟨10.3389/fphys.2018.01168⟩. ⟨hal-02627730⟩

Elise Bordet, Pauline Maisonnasse, Patricia Renson, Edwige Bouguyon, Elisa Crisci, et al.. Porcine Alveolar Macrophage-like cells are pro-inflammatory Pulmonary Intravascular Macrophages that produce large titers of Porcine Reproductive and Respiratory Syndrome Virus. Scientific Reports, Nature Publishing Group, 2018, 8, ⟨10.1038/s41598-018-28234-y⟩. ⟨hal-02623426⟩

Pierre Louis Hervé, Charlotte Deloizy, Delphyne Descamps, Marie-Anne Rameix Welti, Jenna Fix, et al.. RSV N-nanorings fused to palivizumab-targeted neutralizing epitope as a nanoparticle RSV vaccine. Nanomedicine: Nanotechnology, Biology and Medicine, Elsevier, 2017, 13 (2), pp.411-420. ⟨10.1016/j.nano.2016.08.006⟩. ⟨hal-02628338⟩

Carole Drajac, Daphnée Laubreton, Sabine Riffault, Delphyne Descamps. Pulmonary susceptibility of neonates to respiratory syncytial virus infection: a problem of innate immunity?. Journal of Immunology Research, Hindawi Publishing Corporation, 2017, ⟨10.1155/2017/8734504⟩. ⟨hal-02628884⟩

Joël Babdor, Delphyne Descamps, Adiko Assi Aimé Cézaire, Mira Tohmé, Sophia Maschalidi, et al.. IRAP+ endosomes restrict TLR9 activation and signaling. Nature Immunology, Nature Publishing Group, 2017, 18 (5), pp.509-518. ⟨10.1038/ni.3711⟩. ⟨inserm-01674784⟩

Dania Zhivaki, Sebastien Lemoine, Annick Lim, Ahsen Morva, Pierre-Olivier Vidalain, et al.. Respiratory Syncytial Virus Infects Regulatory B Cells in Human Neonates via Chemokine Receptor CX3CR1 and Promotes Lung Disease Severity. Immunity, Elsevier, 2017, 46 (2), pp.301-314. ⟨10.1016/j.immuni.2017.01.010⟩. ⟨hal-01604975⟩

Aude Remot-Brizion, Delphyne Descamps, Marie-Louise Noordine, Abdelhak Boukadiri, Elliot Mathieu, et al.. Bacteria isolated from lung modulate asthma susceptibility in mice. ISME Journal, Nature Publishing Group, 2017, pp.1-14. ⟨10.1038/ismej.2016.181⟩. ⟨hal-01595509⟩

Aude Remot-Brizion, Delphyne Descamps, Luc Jouneau, Daphnée Laubreton, Catherine Dubuquoy, et al.. Flt3 ligand improves the innate response to respiratory syncytial virus and limits lung disease upon RSV reexposure in neonate mice. European Journal of Immunology, Wiley-VCH Verlag, 2016, 46 (4), pp.874-884. ⟨10.1002/eji.201545929⟩. ⟨hal-01533877⟩

Pierre-Louis Hervé, Delphyne Descamps, Charlotte Deloizy, Véronique Dhelft, Daphné Laubreton, et al.. Non-invasive epicutaneous vaccine against Respiratory Syncytial Virus: Preclinical proof of concept. Journal of Controlled Release, Elsevier, 2016, 243, pp.146-159. ⟨10.1016/j.jconrel.2016.10.003⟩. ⟨hal-01425790⟩

Mathieu Le Gars, Delphyne Descamps, Delphine Roussel, Emilie Saussereau, Loïc Guillot, et al.. Neutrophil Elastase Degrades Cystic Fibrosis Transmembrane Conductance Regulator via Calpains and Disables Channel Function In Vitro and In Vivo. American Journal of Respiratory and Critical Care Medicine, American Thoracic Society, 2013, 187 (2), pp.170-179. ⟨10.1164/rccm.201205-0875OC⟩. ⟨inserm-02448131⟩

Delphyne Descamps, Bénédicte Manoury. Detection of influenza viruses by Toll-like receptors: major interactions in the control of responses to flu shots. Virologie, John Libbey Eurotext 2013, 17 (5), pp.369 - 378. ⟨hal-02645786⟩

Diane Barbier, Ignacio Garcia-Verdugo, Julien Pothlichet, Roxana Khazen, Delphyne Descamps, et al.. Influenza A induces the major secreted airway mucin MUC5AC in a protease–EGFR–extracellular regulated kinase–Sp1–dependent pathway. American Journal of Respiratory Cell and Molecular Biology, American Thoracic Society, 2012, 47 (2), pp.149-157. ⟨10.1165/rcmb.2011-0405OC⟩. ⟨hal-02647480⟩

Delphyne Descamps, Le Gars Mathieu, Viviane Balloy, Barbier Diane, Maschalidi Sophia, et al.. Toll-like receptor 5 (TLR5), IL-1β secretion, and asparagine endopeptidase are critical factors for alveolar macrophage phagocytosis and bacterial killing.. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2012, 109 (5), pp.1619-24. ⟨10.1073/pnas.1108464109⟩. ⟨pasteur-00667246⟩

Sophia Maschalidi, Signe Hässler, Fany Blanc, Fernando E. Sepulveda, Mira Tohmé, et al.. Asparagine endopeptidase controls anti-influenza virus immune responses through TLR7 activation. PLoS Pathogens, Public Library of Science, 2012, 8 (8), ⟨10.1371/journal.ppat.1002841⟩. ⟨hal-02645446⟩

Delphyne Descamps, Benedicte Manoury, Jean-Michel Sallenave. le TLR5: un partenaire crucial pour la phagocytose et l'élimination de Pseudomonas aeruginosa par les macrophages alvéolaires impliquant l'IL-1b et l'aspragine endopeptidase. SFI Actualités, 2012, pp.10-12. ⟨hal-01606733⟩

Ronan Le Goffic, Olivier Leymarie, Christophe Chevalier, Emmanuelle Rebours, Bruno da Costa, et al.. Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein.. PLoS Pathogens, Public Library of Science, 2011, 7 (8), pp.e1002202. ⟨10.1371/journal.ppat.1002202⟩. ⟨hal-00684735⟩

Jean-Paul Motta*, Laurent Magne*, Delphyne Descamps, Corinne Rolland, Camila Squarzoni-Dale, et al.. Modifying the Protease, Antiprotease Pattern by Elafin Overexpression Protects Mice From Colitis. Gastroenterology, WB Saunders, 2010, 140 (4), pp.1272-82. ⟨10.1053/j.gastro.2010.12.050⟩. ⟨pasteur-00552947⟩

Anne Denys, Allan Thiolat, Delphyne Descamps, Delphine Lemeiter, Karim Benihoud, et al.. Intra-articular electrotransfer of mouse soluble tumour necrosis factor receptor in a murine model of rheumatoid arthritis. The Journal of Gene Medicine, Wiley, 2010, 12, pp.659-68. ⟨10.1002/jgm.1482⟩. ⟨hal-01601876⟩

Ignacio Garcia-Verdugo, Delphyne Descamps, Michel Chignard, Lhousseine Touqui, Jean-Michel Sallenave. Lung protease/anti-protease network and modulation of mucus production and surfactant activity. Biochimie, Elsevier, 2010, 92 (11), pp.1608-1617. ⟨10.1016/j.biochi.2010.05.010⟩. ⟨hal-01601355⟩

Delphyne Descamps, Karim Benihoud. Two key challenges for effective adenovirus-mediated liver gene therapy: innate immune responses and hepatocyte-specific transduction.. Current Gene Therapy, Bentham Science Publishers, 2009, 9 (2), pp.115-127. ⟨10.2174/156652309787909544⟩. ⟨hal-01601628⟩

Frédéric Vigant, Delphyne Descamps, Betsy Jullienne, Stéphanie Esselin, Elisabeth Connault, et al.. Substitution of hexon hypervariable region 5 of adenovirus serotype 5 abrogates blood factor binding and limits gene transfer to liver.. Molecular Therapy, Nature Publishing Group, 2008, 16 (8), pp.1474-80. ⟨10.1038/mt.2008.132⟩. ⟨hal-00315859⟩

K Benihoud, S. Esselin, Delphyne Descamps, B Jullienne, B. Salone, et al.. Respective roles of TNF-alpha and IL-6 in the immune response-elicited by adenovirus-mediated gene transfer in mice. Gene Therapy, Nature Publishing Group, 2007, 14 (6), pp.533-544. ⟨10.1038/sj.gt.3302885⟩. ⟨hal-01605088⟩

Aude Remot, Jennifer Palomo, Alexandre David-Hachette, Elliot Mathieu, Delphyne Descamps, et al.. Bacteria isolated from lung as biotherapeutics in asthma. ERS International Congress 2019 abstracts, Nov 2019, Madrid, Spain. pp.OA3593, ⟨10.1183/13993003.congress-2019.OA3593⟩. ⟨hal-02987807⟩

Pierre-Louis Hervé, Delphyne Descamps, Charlotte Deloizy, Veronique Dhelft, Daphne Laubreton, et al.. Preclinicalevaluation of anovel non-Invasive epicutaneous vaccine against respiratory syncytial virus. Annual Meeting of the American-Academy-of-Allergy-Asthma-and-Immunology, Mar 2017, Atlanta, Georgia. pp.1. ⟨hal-01605167⟩

D. Zhivaki, S. Lemoine, M. -A Rameix-Welti, A. Lim, Delphyne Descamps, et al.. Respiratory syncytial virus targets a fetally developed B cell population with regulatory functions which predicts disease severity. International Congress of Immunology (ICI), Aug 2016, Melbourne, Australia. pp.1. ⟨hal-02742028⟩

Aude Remot, Marie-Louise Noordine, Chantal Bridonneau, Delphyne Descamps, Sabine Riffault, et al.. Impact of the development of the lung microbiota on neonatal immunity. 20. Colloque du Club des Bactéries Lactiques, Jun 2015, Lille, France. ⟨hal-02742693⟩

Pierre Louis Hervé, Charlotte Deloizy, Nicolas Bertho, Thierry Chaumeil, Maud Renouard, et al.. Preclinical Evaluation of a Novel Epicutaneous Vaccine against Respiratory Syncytial Virus. 10. World Processing Tomato Congress "Tomato Processing & Emerging Markets" and the 12. International Symposium on the Processing Tomato, Nov 2015, California, United States. ⟨hal-02742873⟩

Aude Remot, Luc Jouneau, Delphyne Descamps, Catherine Dubuquoy, Stephan Bouet, et al.. Lung neonatal responses to respiratory syncytial virus reveal deficiencies in dendritic cells and type I interferon in a mouse model of airway enhanced disease. 8. Word Immune Regulation Meeting, Mar 2014, Davos, Switzerland. ⟨hal-02740120⟩

Christophe Richard, Thierry Meylheuc, Pierre Adenot, Stephane Biacchesi, Delphyne Descamps, et al.. MIMA 2 Imaging Plateform. Aviesan, Symposium “Translational research on diabetic cardiomyopathy”, Jun 2019, Paris, France. 2019, ITMO " Translational research on diabetic cardiomyopathy". ⟨hal-02736096⟩

Carole Drajac, Daphnée Laubreton, Loredana Saveanu, Sabine Riffault, Delphyne Descamps. Control of nonatal type I interferon responses by IRAP upon RSV infection. IRAP 2017, 3rd international symposium, 2017, Paris, France. 2017. ⟨hal-01605602⟩

Aude Remot, Alix Penel, Mathilde Bauducel, Chantal Bridonneau, Delphyne Descamps, et al.. Impact of the development of the pulmonary microbiota on neonatal immunity. 8. Word Immune Regulation Meeting, Mar 2014, Davos, Switzerland. 2014. ⟨hal-02742629⟩

Aude Remot, Delphyne Descamps, Luc Jouneau, Catherine Dubuquoy, Stephan Bouet, et al.. Lung neonatal responses to respiratory syncytial virus reveal deficiencies in dendritic cells and type I interferon in a mouse model of airway enhanced disease. 13. International Symposium on Dendritic Cells, Sep 2014, Tours, France. 2014. ⟨hal-02739158⟩

Aude Remot, Alix Penel, Mathilde Bauducel, Chantal Bridonneau, Delphyne Descamps, et al.. Impact of the development of the pulmonary microbiota on neonatal immunity. AgreenSkills Annual Meeting 2013, Nov 2013, Louvain, Belgium. 87 p., 2013. ⟨hal-02748060⟩

Delphyne Descamps, Bénédicte Manoury, Jean-Michel Sallenave. Pseudomonas aeruginosas: a model of pathogen with multiple virulence factors for the study of innate immune defense in lung. Bacterial Pathogens: Virulence mechanims, dignosis and management., Nova Science Publishers, 187 p., 2012, 978-1-62081-887-9. ⟨hal-01605349⟩