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CMV and Immunosenescence: from basics to clinics

Rafael Solana , Raquel Tarazona , Allison Aiello , Arne Akbar , Victor Appay , et al.
Immunity & Ageing, 2012, 9 (1), ⟨10.1186/1742-4933-9-23⟩
Article dans une revue hal-02455353v1

Coordinated expansion of both memory T cells and NK cells in response to CMV infection in humans

Charles Bayard , Hélène Lepetitcorps , Antoine Roux , Martin Larsen , Solène Fastenackels , et al.
European Journal of Immunology, 2016, 46 (5), pp.1168-1179. ⟨10.1002/eji.201546179⟩
Article dans une revue hal-02452542v1
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HIV-mediated immune aging in young adults infected perinatally or during childhood

Solène Fastenackels , Delphine Sauce , Corinne Vigouroux , Véronique Avettand-Fenoel , Jean-Philippe Bastard , et al.
AIDS. Official journal of the international AIDS Society, 2019, 33 (11), pp.1705-1710. ⟨10.1097/QAD.0000000000002275⟩
Article dans une revue hal-02446214v1
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Reduced naïve CD8+T-cell priming efficacy in elderly adults

Olivia Briceño , Anna Lissina , Kerstin Wanke , Georgia Afonso , Amrei von Braun , et al.
Aging Cell, 2015, 15 (1), pp.14-21 ⟨10.1111/acel.12384⟩
Article dans une revue hal-01218054v1

Thymectomie et infection virale chez l’homme

Delphine Sauce , Victor Appay
Médecine/Sciences, 2010, 26 (4), pp.347-349. ⟨10.1051/medsci/2010264347⟩
Article dans une revue hal-02455361v1
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Evidence of premature immune aging in patients thymectomized during early childhood.

Delphine Sauce , Martin Larsen , Solène Fastenackels , Anne Duperrier , Michael Keller , et al.
Journal of Clinical Investigation, 2009, 119 (10), pp.3070-8. ⟨10.1172/JCI39269⟩
Article dans une revue inserm-00484608v1
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HIV-specific Th2 and Th17 responses predict HIV vaccine protection efficacy

Delphine Sauce , Guy Gorochov , Martin Larsen
Scientific Reports, 2016, 6 (1), pp.28129. ⟨10.1038/srep28129⟩
Article dans une revue hal-01340575v1

Reduced Oxidative Burst by Primed Neutrophils in the Elderly Individuals Is Associated With Increased Levels of the CD16(bright)/CD62L(dim) Immunosuppressive Subset

Delphine Sauce , Yuan Dong , Laure Campillo-Gimenez , Sarah Casulli , Charles Bayard , et al.
Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2017, 72 (2), pp.163-172. ⟨10.1093/gerona/glw062⟩
Article dans une revue hal-01545496v1

Correction: Pathogen-Specific T Cell Polyfunctionality Is a Correlate of T Cell Efficacy and Immune Protection

Anders Boyd , Jorge Almeida , Patricia Darrah , Delphine Sauce , Robert Seder , et al.
PLoS ONE, 2015, 10 (9), pp.e0138395. ⟨10.1371/journal.pone.0138395⟩
Article dans une revue hal-02452548v1

Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity

Jorge Almeida , Delphine Sauce , David L. Price , Laura Papagno , So Youn Shin , et al.
Blood, 2009, 113 (25), pp.6351-6360. ⟨10.1182/blood-2009-02-206557⟩
Article dans une revue hal-02455368v1

Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover

Jorge Almeida , David L. Price , Laura Papagno , Zaïna Aït Arkoub , Delphine Sauce , et al.
Journal of Experimental Medicine, 2007, 204 (10), pp.2473-2485. ⟨10.1084/jem.20070784⟩
Article dans une revue hal-02455369v1

Exhausted Cytotoxic Control of Epstein-Barr Virus in Human Lupus

Martin Larsen , Delphine Sauce , Claire Deback , Laurent Arnaud , Alexis Mathian , et al.
PLoS Pathogens, 2011, 7 (10), pp.e1002328. ⟨10.1371/journal.ppat.1002328⟩
Article dans une revue hal-02455358v1

Influence de PD-1 sur la synapse immunologique

Martin Larsen , Victor Appay , Delphine Sauce
Médecine/Sciences, 2013, 29 (12), pp.1080-1082. ⟨10.1051/medsci/20132912006⟩
Article dans une revue hal-02455350v1
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CMV and Immunosenescence: from basics to clinics.

Rafael Solana , Raquel Tarazona , Allison Aiello , Arne Akbar , Victor Appay , et al.
Immunity & Ageing, 2012, 9 (1), pp.23. ⟨10.1186/1742-4933-9-23⟩
Article dans une revue inserm-00796144v1

Elderly human hematopoietic progenitor cells express cellular senescence markers and are more susceptible to pyroptosis

Tinhinane Fali , Véronique Fabre-Mersseman , Takuya Yamamoto , Charles Bayard , Laura Papagno , et al.
JCI Insight, 2018, 3 (13), ⟨10.1172/jci.insight.95319⟩
Article dans une revue hal-02452400v1
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The link between CD8⁺ T-cell antigen-sensitivity and HIV-suppressive capacity depends on HLA restriction, target epitope and viral isolate

Anna Lissina , Solène Fastenackels , Maria C. Inglesias , Kristin Ladell , James E. Mclaren , et al.
AIDS. Official journal of the international AIDS Society, 2014, 28 (4), pp.477--486. ⟨10.1097/QAD.0000000000000175⟩
Article dans une revue pasteur-01420522v1
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Pathogen-Specific T Cell Polyfunctionality Is a Correlate of T Cell Efficacy and Immune Protection

Anders Boyd , Jorge R. Almeida , Patricia A. Darrah , Delphine Sauce , Robert A. Seder , et al.
PLoS ONE, 2015, 10 (6), pp.e0128714. ⟨10.1371/journal.pone.0128714⟩
Article dans une revue hal-01230981v1

Alloreactivity of ex vivo-expanded T cells is correlated with expansion and CD4/CD8 ratio.

Patricia Mercier-Letondal , Nicolas Montcuquet , Delphine Sauce , Jean-Marie Certoux , Sylvie Jeanningros , et al.
Cytotherapy, 2008, 10 (3), pp.275-88. ⟨10.1080/14653240801927032⟩
Article dans une revue inserm-00483384v1
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Primary immune responses are negatively impacted by persistent herpesvirus infections in older people: results from an observational study on healthy subjects and a vaccination trial on subjects aged more than 70 years old

Francesco Nicoli , Emmanuel Clave , Kerstin Wanke , Amrei von Braun , Vincent Bondet , et al.
EBioMedicine, 2022, 76, pp.103852. ⟨10.1016/j.ebiom.2022.103852⟩
Article dans une revue hal-03559977v1

Evaluating Cellular Polyfunctionality with a Novel Polyfunctionality Index

Martin Larsen , Delphine Sauce , Laurent Arnaud , Solène Fastenackels , Victor Appay , et al.
PLoS ONE, 2012, 7 (7), pp.e42403. ⟨10.1371/journal.pone.0042403⟩
Article dans une revue hal-02455355v1
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New Insights into Lymphocyte Differentiation and Aging from Telomere Length and Telomerase Activity Measurements

Tinhinane Fali , Laura Papagno , Charles Bayard , Yanis Mouloud , Jacques Boddaert , et al.
Journal of Immunology, 2019, 202 (7), pp.1962-1969. ⟨10.4049/jimmunol.1801475⟩
Article dans une revue hal-02352254v1
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Impact of stress on aged immune system compartments: Overview from fundamental to clinical data

Tinhinane Fali , Hélène Vallet , Delphine Sauce
Experimental Gerontology, 2018, 105, pp.19-26. ⟨10.1016/j.exger.2018.02.007⟩
Article dans une revue hal-02352184v1

New advances in CMV and immunosenescence

Paolo Sansoni , Rosanna Vescovini , Francesco Fagnoni , Arne Akbar , Ramon Arens , et al.
Experimental Gerontology, 2014, 55, pp.54-62. ⟨10.1016/j.exger.2014.03.020⟩
Article dans une revue hal-02455348v1

The role of the thymus in immunosenescence: lessons from the study of thymectomized individuals

Victor Appay , Delphine Sauce , Martina Prelog
Aging, 2010, 2 (2), pp.78-81. ⟨10.18632/aging.100122⟩
Article dans une revue hal-02455362v1
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Preservation of Lymphopoietic Potential and Virus Suppressive Capacity by CD8+ T Cells in HIV-2-Infected Controllers.

Mathieu Angin , Glenn Wong , Laura Papagno , Pierre Versmisse , Annie David , et al.
Journal of Immunology, 2016, 197 (7), pp.2787-95. ⟨10.4049/jimmunol.1600693⟩
Article dans une revue hal-01406621v1
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Elevated Neopterin Levels Predict Fatal Outcome in SARS-CoV-2-Infected Patients

Manon Chauvin , Martin Larsen , Bibiana Quirant , Paul Quentric , Karim Dorgham , et al.
Frontiers in Cellular and Infection Microbiology, 2021, 11, pp.709893. ⟨10.3389/fcimb.2021.709893⟩
Article dans une revue hal-03354284v1
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Hip Fracture Leads to Transitory Immune Imprint in Older Patients

Héléne Vallet , Charles Bayard , Héléne Lepetitcorps , Jessica O'Hana , Solène Fastenackels , et al.
Frontiers in Immunology, 2020, 11, pp.571759. ⟨10.3389/fimmu.2020.571759⟩
Article dans une revue hal-02978739v1

Reduced naïve CD8 + T-cell priming efficacy in elderly adults

Olivia Briceno , Anna Lissina , Kerstin Wanke , Georgia Afonso , Amrei von Braun , et al.
Aging Cell, 2016, 15 (1), pp.14-21. ⟨10.1111/acel.12384⟩
Article dans une revue hal-02452545v1

Assessing T Lymphocyte Aging Using Telomere Length and Telomerase Activity Measurements in Low Cell Numbers

Tinhinane Fali , Camille K’ros , Victor Appay , Delphine Sauce
In Vitro Differentiation of T-Cells, 2048, Springer New York, pp.231-243, 2019, Methods in Molecular Biology, ⟨10.1007/978-1-4939-9728-2_18⟩
Chapitre d'ouvrage hal-03898571v1
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Mechanisms of immune aging in HIV

Manon Chauvin , Delphine Sauce
Clinical Science, 2022, 136 (1), pp.61-80. ⟨10.1042/CS20210344⟩
Article dans une revue hal-03826161v1