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Delphine Fradin 2020

Journal articles32 documents

  • L. Ollivier, V. Guimas, E. Rio, L. Vaugier, I. Masson, et al.. Combinaison radiothérapie-immunothérapie en cancérologie génito-urinaire. Cancer Radiothérapie, Elsevier Masson, 2021, 25 (6-7), pp.565-569. ⟨10.1016/j.canrad.2021.06.033⟩. ⟨inserm-03540455⟩
  • Luc Ollivier, Maureen Labbé, Delphine Fradin, Vincent Potiron, Stéphane Supiot. Interaction Between Modern Radiotherapy and Immunotherapy for Metastatic Prostate Cancer. Frontiers in Oncology, Frontiers, 2021, 11, pp.744679. ⟨10.3389/fonc.2021.744679⟩. ⟨inserm-03369787⟩
  • Romain Vallion, Jordane Divoux, Salomé Glauzy, Emilie Ronin, Yannis Lombardi, et al.. Regulatory T Cell Stability and Migration Are Dependent on mTOR. Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2020, 205 (7), pp.1799-1809. ⟨10.4049/jimmunol.1901480⟩. ⟨inserm-02946304⟩
  • Tiphaine Delaunay, Carole Achard, Nicolas Boisgerault, Marion Grard, Tacien Petithomme, et al.. Frequent Homozygous Deletions of Type I Interferon Genes in Pleural Mesothelioma Confer Sensitivity to Oncolytic Measles Virus: Interferon genes loss sensitizes tumor cells to viral lysis. Journal of Thoracic Oncology, Lippincott, Williams & Wilkins, 2020, S1556-0864(20)30019-8, Epub ahead of print. ⟨10.1016/j.jtho.2019.12.128⟩. ⟨inserm-02447160⟩
  • Tiphaine Parrot, Romain Oger, Mathilde Allard, Juliette Desfrançois, Diane Raingeard de La Blétìère, et al.. Transcriptomic features of tumour- infiltrating CD4 low CD8 high double positive αβ T cells in melanoma. Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.5900. ⟨10.1038/s41598-020-62664-x⟩. ⟨inserm-02534481⟩
  • Lyna Kara-Terki, Lucas Treps, Christophe Blanquart, Delphine Fradin. Critical Roles of Tumor Extracellular Vesicles in the Microenvironment of Thoracic Cancers. International Journal of Molecular Sciences, MDPI, 2020, 21 (17), pp.6024. ⟨10.3390/ijms21176024⟩. ⟨inserm-02946311⟩
  • Lucine Marotte, Sylvain Simon, Virginie Vignard, Emilie Dupré, Malika Gantier, et al.. Increased antitumor efficacy of PD-1- deficient melanoma-specific human lymphocytes. Journal for Immunotherapy of Cancer, BMJ Publishing Group 2020, 8, pp.e000311. ⟨10.1136/jitc-2019-000311⟩. ⟨inserm-02481085⟩
  • Maureen Labbé, Christianne Hoey, Jessica Ray, Vincent Potiron, Stephane Supiot, et al.. microRNAs identified in prostate cancer: Correlative studies on response to ionizing radiation. Molecular Cancer, BioMed Central, 2020, 19, pp.63. ⟨10.1186/s12943-020-01186-6⟩. ⟨inserm-02515300⟩
  • Pierre Autin, Christophe Blanquart, Delphine Fradin. Epigenetic Drugs for Cancer and microRNAs: A Focus on Histone Deacetylase Inhibitors. Cancers, MDPI, 2019, 11 (10), pp.1530. ⟨10.3390/cancers11101530⟩. ⟨inserm-02315396⟩
  • Mahtab Samimi, Houssem Benlalam, Pascal Aumond, Pauline Gaboriaud, Delphine Fradin, et al.. Viral and tumor antigen-specific CD8 T-cell responses in Merkel cell carcinoma. Cellular Immunology, Elsevier, 2019, 344, 8 p. ⟨10.1016/j.cellimm.2019.103961⟩. ⟨inserm-02284748⟩
  • Virginie Vignard, Maureen Labbé, Nadège Marec, Gwennan André-Grégoire, Nicolas Jouand, et al.. MicroRNAs in Tumor Exosomes Drive Immune Escape in Melanoma. Cancer Immunology Research, American Association for Cancer Research, 2019, canimm.0522.2019, Epub ahead of print. ⟨10.1158/2326-6066.CIR-19-0522⟩. ⟨inserm-02426329⟩
  • Virginie Vignard, Delphine Fradin. Non-Coding RNAs in Cutaneous Melanoma Development, Progression and Dissemination. OBM Genetics, LIDSEN Publishing Inc., 2018, 2 (2), pp.1 - 1. ⟨10.21926/obm.genet.1802020⟩. ⟨inserm-01804848⟩
  • Catherine Le Stunff, Anne-Laure Castell, Nicolas Todd, Clémence Mille, Marie-Pierre Belot, et al.. Fetal growth is associated with the CpG methylation of the P2 promoter of the IGF1 gene. Clinical Epigenetics, BioMed Central, 2018, 10, pp.57. ⟨10.1186/s13148-018-0489-9⟩. ⟨inserm-01782203⟩
  • Delphine Fradin, Pierre-Yves Boëlle, Marie-Pierre Belot, Fanny Lachaux, Jörg Tost, et al.. Genome-Wide Methylation Analysis Identifies Specific Epigenetic Marks In Severely Obese Children. Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.46311. ⟨10.1038/srep46311⟩. ⟨inserm-02320512⟩
  • Danny Ben-Avraham, Diddahally Govindaraju, Temuri Budagov, Delphine Fradin, Peter Durda, et al.. The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature. Science Advances , American Association for the Advancement of Science (AAAS), 2017, 3 (6), pp.e1602025. ⟨10.1126/sciadv.1602025⟩. ⟨inserm-02320509⟩
  • Marie-Pierre Belot, Kambiz Nadéri, Clémence Mille, Pierre-Yves Boëlle, Alexandra Benachi, et al.. Role of DNA methylation at the placental RTL1 gene locus in type 1 diabetes. Pediatric Diabetes, Wiley, 2017, 18 (3), pp.178-187. ⟨10.1111/pedi.12387⟩. ⟨inserm-02320514⟩
  • Delphine Fradin, Pierre-Yves Boëlle, Marie-Pierre Belot, Fanny Lachaux, Jorg Tost, et al.. Genome-Wide Methylation Analysis Identifies Specific Epigenetic Marks In Severely Obese Children. Scientific Reports, Nature Publishing Group, 2017, 7, pp.46311. ⟨10.1038/srep46311⟩. ⟨hal-01516806⟩
  • M Ouni, M P Belot, A. L. Castell, Delphine Fradin, P Bougnères. The P2 promoter of the IGF1 gene is a major epigenetic locus for GH responsiveness. Pharmacogenomics Journal, Nature Publishing Group, 2016, 16, pp.102-106. ⟨10.1038/tpj.2015.26⟩. ⟨hal-02329906⟩
  • Meriem Ouni, Marie Pierre Belot, Anne-Laure Castell, Delphine Fradin, Pierre Bougneres. The IGF1 P2 promoter is an epigenetic QTL for circulating IGF1 and human growth. Clinical Epigenetics, BioMed Central, 2015, 7, pp.22. ⟨10.1186/s13148-015-0062-8⟩. ⟨hal-02459502⟩
  • Benjamin Chalopin, Laetitia Florenceau, Delphine Fradin, Nathalie Labarrière, Agnès Moreau-Aubry. A lineage-specific methylation pattern controls the transcription of the polycistronic mRNA coding MELOE melanoma antigens. Melanoma Research, Lippincott, Williams & Wilkins, 2015, ⟨10.1097/CMR.0000000000000167⟩. ⟨inserm-01280880⟩
  • Fabiola Tros, Aline Meirhaeghe, Samy Hadjadj, Philippe Amouyel, Pierre Bougnères, et al.. Hypomethylation of the promoter of the catalytic subunit of protein phosphatase 2A in response to hyperglycemia. Physiological Reports, Wiley, 2014, 2, ⟨10.14814/phy2.12076⟩. ⟨inserm-02459029⟩
  • Delphine Fradin, Pierre Bougnères. β cells keep bad epigenetic memories of palmitate. BMC Medicine, BioMed Central, 2014, 12 (1), ⟨10.1186/1741-7015-12-104⟩. ⟨hal-02329943⟩
  • Marie-Pierre Belot, Delphine Fradin, Nga Mai, Sophie Le Fur, Diana Zelenika, et al.. CpG Methylation Changes within the IL2RA Promoter in Type 1 Diabetes of Childhood Onset. PLoS ONE, Public Library of Science, 2013, 8 (7), pp.e68093. ⟨10.1371/journal.pone.0068093⟩. ⟨hal-02329956⟩
  • Nicolas Le may, Delphine Fradin, Izarn Iltis, Pierre Bougneres, Jean Marc Egly. XPG and XPF Endonucleases Trigger Chromatin Looping and DNA Demethylation for Accurate Expression of Activated Genes. Molecular Cell, Cell Press, 2012, 47 (4), pp.622-632. ⟨10.1016/j.molcel.2012.05.050⟩. ⟨hal-02329959⟩
  • Delphine Fradin, Sophie Le Fur, Clémence Mille, Nadia Naoui, Chris Groves, et al.. Association of the CpG Methylation Pattern of the Proximal Insulin Gene Promoter with Type 1 Diabetes. PLoS ONE, Public Library of Science, 2012, 7 (5), pp.e36278. ⟨10.1371/journal.pone.0036278⟩. ⟨hal-02329970⟩
  • Delphine Fradin, Pierre Bougneres. T2DM: Why Epigenetics?. Journal of Nutrition and Metabolism, 2011, 2011, pp.1-17. ⟨10.1155/2011/647514⟩. ⟨hal-02329973⟩
  • Delphine Fradin, Keely Cheslack-Postava, Christine Ladd-Acosta, Craig Newschaffer, Aravinda Chakravarti, et al.. Parent-Of-Origin Effects in Autism Identified through Genome-Wide Linkage Analysis of 16,000 SNPs. PLoS ONE, Public Library of Science, 2010, 5 (9), pp.e12513. ⟨10.1371/journal.pone.0012513⟩. ⟨hal-02329988⟩
  • Delphine Fradin, Rafael A Irizarry, Martin J Aryee, Peter Murakami, Thor Aspelund, et al.. Personalized Epigenomic Signatures That Are Stable Over Time and Covary with Body Mass Index. Science Translational Medicine, American Association for the Advancement of Science (AAAS), 2010, 2 (49), pp.49ra67-49ra67. ⟨10.1126/scitranslmed.3001262⟩. ⟨hal-02329984⟩
  • Anya Rothenbuhler, Chantal Lotton, Delphine Fradin. Three Common Variants of LEP, NPY1R and GPR54 Show No Association with Age at Menarche. Hormone Research in Paediatrics, Karger, 2009, 71 (6), pp.331-335. ⟨10.1159/000223417⟩. ⟨hal-02329997⟩
  • Delphine Fradin, M Daniele Fallin. Influence of control selection in genome-wide association studies: the example of diabetes in the Framingham Heart Study. BMC Proceedings, BioMed Central, 2009, 3 (S7), ⟨10.1186/1753-6561-3-S7-S113⟩. ⟨hal-02329993⟩
  • Delphine Fradin, Pierre Bougneres. Three Common Intronic Variants in the Maternal and Fetal Thiamine Pyrophosphokinase Gene (TPK1) are Associated with Birth Weight. Annals of Human Genetics, Wiley, 2007, ⟨10.1111/j.1469-1809.2007.00348.x⟩. ⟨hal-02459482⟩
  • Delphine Fradin, Pascal Boileau, Jacques Lepercq, Pierre Bougneres. 'Non-Mendelian' genetics of fetal growth. Journal of Endocrinological Investigation, Springer, 2006, 29 (Supp 1), pp.11-15. ⟨hal-02459429⟩

Conference papers9 documents

  • Delphine Fradin. ExomiR : Etude des microARNs des exosomes tumoraux. 13ème journées du Cancéropole Grand Ouest, Jul 2019, Tours, France. ⟨hal-02459683⟩
  • Delphine Fradin, Nicolas Jouand. INTERNALISATION DES EXOSOMES DE MELANOME PAR LES LYMPHOCYTES T CD8+ ET IMPACT SUR LEURS FONCTIONS : APPORT DU CYTOMETRE IMAGEUR. Journée Imagerie fonctionnelle pré-clinique, Jun 2019, Rennes, France. ⟨hal-02459677⟩
  • Delphine Fradin. L'EPIGENETIQUE, C'EST QUOI ?. 22ème journées de Médecine Foetale, Mar 2017, Nice, France. ⟨hal-02459664⟩
  • Delphine Fradin. Influence de l'hyperglycémie sur la méthylation de l'ADN. Automnales du GRRC, Nov 2015, Pornichet, France. ⟨hal-02459651⟩
  • Delphine Fradin. EVOLUTION DES MARQUES ÉPIGÉNÉTIQUES AU COURS DE LA VIE. ADELF-EPITER, Sep 2014, Nice, France. ⟨hal-02459594⟩
  • Delphine Fradin. EPIGÉNÉTIQUE ET HYPERGLYCÉMIE : RÔLE DE LA MÉTHYLATION DANS LA RÉTINOPATHIE DIABÉTIQUE. 4e congrès annuel du CORDDIM, Sep 2012, Paris, France. ⟨hal-02459620⟩
  • Delphine Fradin. GÉNÉTIQUE ET ÉPIGÉNÉTIQUE DU COMPORTEMENT SOCIAL. Journées de l'Ecole Doctorale Pierre Louis de Santé Publique, Oct 2012, Saint Malo, France. ⟨hal-02459610⟩
  • Delphine Fradin. Aging and DNA methylation. Seventh Annual Grantee Meeting of Centers of Excellence in Genomic Science, Oct 2009, Huntsville, United States. ⟨hal-02459631⟩

Poster communications2 documents

  • Virginie Vignard, Nathalie Labarrière, Delphine Fradin. ROLE OF miRNA FROM MELANOMA CELL-DERIVED EXOSOMES IN TUMOR IMMUNE ESCAPE. Extracellular Vesicles in Therapeutics & Healthy Diet, Jun 2017, Nantes, France. ⟨hal-02459718⟩
  • Delphine Fradin, Clémence Mille, Nadia Naoui, Chris Groves, Mark Mccarthy, et al.. Allele Dependent DNA Methylation of the Human Insulin Gene Promoter in T2D patients and Controls. Epigenomics of Common Diseases, Oct 2012, Baltimore, United States. ⟨hal-02459574⟩