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Discovery of a Novel Broad-Spectrum Antifungal Agent Derived from Albaconazole

 Rémi Guillon , Fabrice Pagniez , Carine Picot , Damien Hédou , Alain Tonnerre , et al.
ACS Medicinal Chemistry Letters, 2013, 4 (2), pp.288-292. ⟨10.1021/ml300429p⟩
Article dans une revue hal-01015468v1
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Novel Multitarget-Directed Ligands (MTDLs) with Acetylcholinesterase (AChE) Inhibitory and Serotonergic Subtype 4 Receptor (5-HT 4 R) Agonist Activities As Potential Agents against Alzheimer’s Disease: The Design of Donecopride

 Cédric Lecoutey , Cédric Lecoutey , Florence Gaven , Patrizia Giannoni , Katia Hamidouche , et al.
Journal of Medicinal Chemistry, 2015, 58 (7), pp.3172-3187. ⟨10.1021/acs.jmedchem.5b00115⟩
Article dans une revue hal-02043873v1
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Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment

 Cédric Lecoutey , Damien Hedou , Thomas Freret , Patrizia Giannoni , Florence Gaven , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (36), pp.E3825--30. ⟨10.1073/pnas.1410315111⟩
Article dans une revue hal-01800439v2

Novel synthesis of angular thiazolo[5,4-f] and [4,5-h]quinazolines, preparation of their linear thiazolo[4,5-g] and [5,4-g]quinazoline analogs

 Damien Hédou , Rémi Guillon , Charlotte Lecointe , Cédric Logé , Elizabeth Chosson , et al.
Tetrahedron, 2013, 69 (15), pp.3182-3191. ⟨10.1016/j.tet.2013.02.066⟩
Article dans une revue istex hal-01015586v1
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Design and Synthesis of Thiazolo[5,4-f]quinazolines as DYRK1A Inhibitors, Part I

 Alicia Foucourt , Damien Hédou , Carole Dubouilh-Benard , Laurent Désiré , Anne-Sophie Casagrande , et al.
Molecules, 2014, 19 (10), pp.15546-15571. ⟨10.3390/molecules191015546⟩
Article dans une revue hal-01141172v1
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Design and Synthesis of Thiazolo[5,4-f]quinazolines as DYRK1A Inhibitors, Part II

 Alicia Foucourt , Damien Hédou , Carole Dubouilh-Benard , Angelique Girard , Thierry Taverne , et al.
Molecules, 2014, 19 (10), pp.15411-15439. ⟨10.3390/molecules191015411⟩
Article dans une revue hal-01135223v1

Rational multistep synthesis of a novel polyfunctionalized benzo[d]thiazole and its thiazolo[5,4-b]pyridine analogue

 Damien Hédou , Emmanuel Deau , Marine Harari , Morgane Sanselme , Corinne Fruit , et al.
Tetrahedron, 2014, 70 (5541-5549), pp.5541-5549. ⟨10.1016/j.tet.2014.06.103⟩
Article dans une revue hal-01141181v1

Synthesis and biological evaluation of new thiazolo [5,4-f]quinazolines as serine/threonine kinases inhibitors

 Damien Hédou , Corinne Fruit , Casagrande Anne-Sophie , Laurent Désiré , Bertrand Leblond , et al.
International Electronic Conference on Medicinal Chemistry (ECMC, 1, 2015), Jean-Jacques Vanden Eynde (coord.), Nov 2015, [online], Belgium. ⟨10.3390/ecmc-1-A047⟩
Communication dans un congrès hal-02383857v1

Synthesis of Bioactive 2-(arylamino)thiazolo[5,4-f]-quinazolin-9-ones via the Hügershoff Reaction or Cu- Catalyzed Intramolecular C-S Bond Formation

 Damien Hédou , Carole Dubouilh-Benard , Nadège Loaëc , Meijer Laurent , Corinne Fruit , et al.
International Electronic Conference on Medicinal Chemistry (ECMC, 2, 2016), Jean-Jacques Vanden Eynde (coord.), Nov 2016, [online], Belgium. ⟨10.3390/ecmc-2-A010⟩
Communication dans un congrès hal-02383867v1

Microwave-Assisted [3+2] Cycloaddition and Suzuki-Miyaura Cross-Coupling for a Concise Access to Polyaromatic Scaffolds

 Damien Hédou , Emmanuel Deau , Carole Dubouilh-Benard , Morgane Sanselme , Anthony Martinet , et al.
European Journal of Organic Chemistry, 2013, 2013 (33), pp.7533-7545. ⟨10.1002/ejoc.201301014⟩
Article dans une revue istex hal-01015445v1

Synthesis of polyfunctionalized benzo[d]thiazoles as novel anthranilic acid derivatives

 Damien Hédou , Marine Harari , Julien Godeau , Carole Dubouilh-Benard , Corinne Fruit , et al.
Tetrahedron Letters, 2015, 56 (27), pp.4088-4092. ⟨10.1016/j.tetlet.2015.05.018⟩
Article dans une revue hal-01160622v1

Convenient one-pot synthesis of N3-substituted pyrido[2,3-d]-, pyrido[3,4-d]-, pyrido[4,3-d]-pyrimidin-4(3H)-ones, and quinazolin-4(3H)-ones analogs

 Emmanuel Deau , Damien Hédou , Elizabeth Chosson , Vincent Levacher , Thierry Besson
Tetrahedron Letters, 2013, 54 (27), pp.3518-3521. ⟨10.1016/j.tetlet.2013.04.096⟩
Article dans une revue istex hal-01015451v1
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Pharmacological Inhibition of Oncogenic STAT3 and STAT5 Signaling in Hematopoietic Cancers

 Marie Brachet-Botineau , Marion Polomski , Heidi Neubauer , Ludovic Juen , Damien Hédou , et al.
Cancers, 2020, 12 (1), pp.240. ⟨10.3390/cancers12010240⟩
Article dans une revue hal-02459040v1
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Synthesis of Thiazolo[5,4-f]quinazolin-9(8H)-ones as Multi-Target Directed Ligands of Ser/Thr Kinases

 Damien Hédou , Julien Godeau , N. Loaëc , L. Meijer , Corinne Fruit , et al.
Molecules, 2016, 21 (5), pp.578. ⟨10.3390/molecules21050578⟩
Article dans une revue hal-02046213v1
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Synthesis of bioactive 2-(arylamino)thiazolo[5,4-f]-quinazolin-9-ones via the Hügershoff reaction or Cu- catalyzed intramolecular C-S bond formation

 Damien Hédou , Carole Dubouilh-Benard , N. Loaëc , L. Meijer , Corinne Fruit , et al.
Molecules, 2016, 21 (6), pp.794. ⟨10.3390/molecules21060794⟩
Article dans une revue hal-02046212v1
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