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Optical Control of Adenosine A 2A Receptor Using Istradefylline Photosensitivity
Anaëlle Dumazer
,
Xavier Gómez-Santacana
,
Fanny Malhaire
,
Chris Jopling
,
Damien Maurel
Article dans une revue
hal-04425630v1
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Photopharmacological manipulation of amygdala metabotropic glutamate receptor mGlu4 alleviates neuropathic pain
Vanessa Pereira
,
Juri Aparicio Arias
,
Amadeu Llebaria
,
Cyril Goudet
Article dans une revue
hal-03914258v1
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Editorial: Molecular mechanisms of nociception
Cyril Goudet
,
Fabien Marchand
Article dans une revue
hal-03805607v1
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Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations
Chady Nasrallah
,
Giuseppe Cannone
,
Julie Briot
,
Karine Rottier
,
Alice Berizzi
Article dans une revue
hal-03340751v1
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THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors
Stephen Alexander
,
Arthur Christopoulos
,
Anthony Davenport
,
Eamonn Kelly
,
Alistair Mathie
Article dans une revue
hal-03875300v1
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International Union of Basic and Clinical Pharmacology. CXI. Pharmacology, Signaling, and Physiology of Metabotropic Glutamate Receptors
Karen J Gregory
,
Cyril Goudet
Article dans une revue
hal-03099669v1
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Les avancées récentes dans le domaine de la biologie structurale des récepteurs couplés aux protéines G de la classe C : Le récepteur métabotropique du glutamate 5
Ludovic Berto
,
Anaëlle Dumazer
,
Fanny Malhaire
,
Giuseppe Cannone
,
Vinothkumar Kutti
Article dans une revue
hal-03744975v2
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Mechanistic insights into light-driven allosteric control of GPCR biological activity
Maria Ricart-Ortega
,
Alice Berizzi
,
Vanessa Pereira
,
Fanny Malhaire
,
Juanlo Catena
Article dans une revue
hal-02924800v1
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Development and validation of a mass spectrometry binding assay for mGlu5 receptor
Maria Ricart-Ortega
,
Alice Berizzi
,
Juanlo Catena
,
Fanny Malhaire
,
Lourdes Muñoz
Article dans une revue
hal-02884945v1
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Emerging Trends in Pain Modulation by Metabotropic Glutamate Receptors
Vanessa Pereira
,
Cyril Goudet
Article dans une revue
hal-02388671v1
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THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein‐coupled receptors
Stephen Alexander
,
Arthur Christopoulos
,
Anthony P Davenport
,
Eamonn Kelly
,
Alistair Mathie
Article dans une revue
hal-02388696v1
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Dynamic modulation of inflammatory pain-related affective and sensory symptoms by optical control of amygdala metabotropic glutamate receptor 4
Charleine Zussy
,
X. Gomez-Santacana
,
Xavier Rovira
,
Dimitri de Bundel
,
S. Ferrazzo
Article dans une revue
hal-02073218v1
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Shedding light on metabotropic glutamate receptors using optogenetics and photopharmacology
Cyril Goudet
,
Xavier Rovira
,
Amadeu Llebaria
Article dans une revue
hal-02388700v1
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Profiling of orthosteric and allosteric group-III metabotropic glutamate receptor ligands on various G protein-coupled receptors with Tag-lite® assays
Abderazak Belhocine
,
Pietro Veglianese
,
Candide Hounsou
,
Elodie Dupuis
,
Francine C. Acher
Article dans une revue
hal-02388698v1
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Increased Potency and Selectivity for Group III Metabotropic Glutamate Receptor Agonists Binding at Dual sites
Chelliah Selvam
,
Isabelle Lemasson
,
Isabelle Brabet
,
Nadia Oueslati
,
Berin Karaman
Article dans une revue
hal-02018007v1
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Chloride ions stabilize the glutamate-induced active state of the metabotropic glutamate receptor 3
Amélie S. Tora
,
Xavier Rovira
,
Anne-Marinette Cao
,
Alexandre Cabaye
,
Linnea Olofsson
Article dans une revue
hal-02346230v1
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Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator
Joan Font
,
Marc López-Cano
,
Serena Notartomaso
,
Pamela Scarselli
,
Paola Di Pietro
Article dans une revue
hal-03549950v1
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Illuminating Phenylazopyridines To Photoswitch Metabotropic Glutamate Receptors: From the Flask to the Animals
Xavier Gómez-Santacana
,
Silvia Pittolo
,
Xavier Rovira
,
Marc Lopez
,
Charleine Zussy
Article dans une revue
hal-02066097v1
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Positional isomers of bispyridine benzene derivatives induce efficacy changes on mGlu 5 negative allosteric modulation
Xavier Gómez-Santacana
,
James Dalton
,
Xavier Rovira
,
Jean-Philippe Pin
,
Cyril Goudet
Article dans une revue
hal-02066019v1
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Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer
Junke Liu
,
Zongyong Zhang
,
David Moreno-Delgado
,
James Ar Dalton
,
Xavier Rovira
Article dans une revue
hal-02073040v1
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New 4-Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group III
Tri H. V. Huynh
,
Mette N. Erichsen
,
Amélie S. Tora
,
Cyril Goudet
,
Emmanuelle Sagot
Article dans une revue
hal-01288609v1
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OptoGluNAM4.1, a Photoswitchable Allosteric Antagonist for Real-Time Control of mGlu4 Receptor Activity
Xavier Rovira
,
Ana Trapero
,
Silvia Pittolo
,
Charleine Zussy
,
Adèle Faucherre
Article dans une revue
hal-01941168v1
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Shining Light on an mGlu5 Photoswitchable NAM: A Theoretical Perspective
James Dalton
,
Isaias Lans
,
Xavier Rovira
,
Fanny Malhaire
,
Xavier Gómez-Santacana
Article dans une revue
hal-02448289v1
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Therapeutic potential of group III metabotropic glutamate receptor ligands in pain
Francine Acher
,
Cyril Goudet
Article dans une revue
hal-01950127v1
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Synthesis and studies on the mGluR agonist activity of FAP4 stereoisomers
Pavel Ivashkin
,
Gérald Lemonnier
,
Amélie S. Tora
,
Jean-Philippe Pin
,
Cyril Goudet
Article dans une revue
hal-01180138v1
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Overlapping binding sites drive allosteric agonism and positive cooperativity in type 4 metabotropic glutamate receptors
Xavier Rovira
,
Fanny Malhaire
,
Pauline Scholler
,
Jordi Rodrigo
,
P. Gonzalez-Bulnes
Article dans une revue
hal-01943324v1
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Determination of the absolute configuration of phosphinic analogues of glutamate
Bruno Commare
,
Delphine Rigault
,
Isabelle Lemasson
,
Patrick Deschamps
,
Alain Tomas
Article dans une revue
hal-02268872v1
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Allosteric modulation of metabotropic glutamate receptors by chloride ions
Amélie S. Tora
,
Xavier Rovira
,
Ibrahima Dione
,
Hugues-Olivier Bertrand
,
Isabelle Brabet
Article dans une revue
hal-02065116v1
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Exploring the active conformation of cyclohexane carboxylate positive allosteric modulators of the type 4 metabotropic glutamate receptor
Xavier Rovira
,
Youssef Harrak
,
Ana Trapero
,
Patricia Gonzalez-Bulnes
,
Fanny Malhaire
Article dans une revue
hal-01943327v1
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An allosteric modulator to control endogenous G protein-coupled receptors with light
S. Pittolo
,
X. Gomez-Santacana
,
K. Eckelt
,
Xavier Rovira
,
J. Dalton
Article dans une revue
hal-01942934v1
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Alleviating Pain Hypersensitivity through Activation of Type 4 Metabotropic Glutamate Receptor
Bruno Vilar
,
Jérôme Busserolles
,
Bing Ling
,
Sophie Laffray
,
Lauriane Ulmann
Article dans une revue
hal-02448295v1
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A novel selective metabotropic glutamate receptor 4 agonist reveals new possibilities for developing subtype selective ligands with therapeutic potential.
Cyril Goudet
,
Bruno Vilar
,
Tiphanie Courtiol
,
Thierry Deltheil
,
Thomas Bessiron
Article dans une revue
hal-01182946v1
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Α-amino-β-fluorocyclopropanecarboxylic acids as a new tool for drug development: synthesis of glutamic acid analogs and agonist activity towards metabotropic glutamate receptor 4.
Gérald Lemonnier
,
Cédric Lion
,
Jean-Charles Quirion
,
Jean-Philippe Pin
,
Cyril Goudet
Article dans une revue
hal-00996602v1
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Cinnabarinic Acid, an Endogenous Metabolite of the Kynurenine Pathway, Activates Type 4 Metabotropic Glutamate Receptors
F. Fazio
,
L. Lionetto
,
G. Molinaro
,
H. Bertrand
,
F. Acher
Article dans une revue
hal-02448364v1
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A new Selective Metabotropic Glutamate Receptor type 4 Agonist Reveals New ways to Develop Subtype Selective Orthosteric Ligands with Potential Therapeutic Effects
Cyril Goudet
,
Bruno Vilar
,
Tiphanie Courtiol
,
Thierry Deltheil
,
Thomas Bessiron
Current Neuropharmacology, 2011, 9 (1), pp.26
Article dans une revue
hal-01384798v1
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Is metabotropic glutamate receptor mGlu4R a good target to treat Parkinson's disease symptoms? Design and evaluation of potent and selective agonists
Isabelle A. Lemasson
,
Chelliah Selvam
,
Nadia Oueslati
,
Isabelle Brabet
,
Tiphanie Courtiol
Abstracts of Papers of the American Chemical Society, 2009, 238
Article dans une revue
hal-01384832v1
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N-{4-Chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-2-hydroxybenzamide (CPPHA) acts through a novel site as a positive allosteric modulator of group 1 metabotropic glutamate receptors.
Yelin Chen
,
Cyril Goudet
,
Jean-Philippe Pin
,
P Jeffrey Conn
Article dans une revue
inserm-00318958v1
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LSP1-2111, a new orthosteric group III mGlur agonist with preferential activity on mGluR4, modulates the striatopallidal synapse and alleviates parkinsonian symptoms
C. Beurrier
,
D. Revy
,
S. Lopez
,
M. Lherondel
,
Cyril Goudet
Article dans une revue
hal-01384860v1
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L-(+)-2-Amino-4-thiophosphonobutyric acid (L-thioAP4), a new potent agonist of group III metabotropic glutamate receptors: increased distal acidity affords enhanced potency.
Chelliah Selvam
,
Cyril Goudet
,
Nadia Oueslati
,
Jean-Philippe Pin
,
Francine C. Acher
Article dans une revue
inserm-00318965v1
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Group III metabotropic glutamate receptors inhibit hyperalgesia in animal models of inflammation and neuropathic pain
Cyril Goudet
,
Eric Chapuy
,
Abdelkrim Alloui
,
Francine Acher
,
Jean-Philippe Pin
Article dans une revue
inserm-00318859v1
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Interaction of novel positive allosteric modulators of metabotropic glutamate receptor 5 with the negative allosteric antagonist site is required for potentiation of receptor responses.
Yelin Chen
,
Yi Nong
,
Cyril Goudet
,
Kamondanai Hemstapat
,
Tomas de Paulis
Article dans une revue
inserm-00319012v1
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Synthesis and biological evaluation of 1-amino-2-phosphonomethylcyclopropanecarboxylic acids, new group III metabotropic glutamate receptor agonists.
Pauline Sibille
,
Sébastien Lopez
,
Isabelle Brabet
,
Ornella Valenti
,
Nadia Oueslati
Article dans une revue
inserm-00318976v1
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D-myo-inositol 1-phosphate as a surrogate of D-myo-inositol 1,4,5-tris phosphate to monitor G protein-coupled receptor activation.
Eric Trinquet
,
Michel Fink
,
Hervé Bazin
,
Florence Grillet
,
Fabrice Maurin
Article dans une revue
inserm-00318996v1
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Asymmetric functioning of dimeric metabotropic glutamate receptors disclosed by positive allosteric modulators.
Cyril Goudet
,
Julie Kniazeff
,
Veronika Hlavackova
,
Fanny Malhaire
,
Damien Maurel
Article dans une revue
inserm-00318925v1
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Allosteric functioning of dimeric class C G-protein-coupled receptors.
Jean-Philippe Pin
,
Julie Kniazeff
,
Jianfeng Liu
,
Virginie Binet
,
Cyril Goudet
Article dans une revue
inserm-00094959v1
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Evidence for a single heptahelical domain being turned on upon activation of a dimeric GPCR.
Veronika Hlavackova
,
Cyril Goudet
,
Julie Kniazeff
,
Alice Zikova
,
Damien Maurel
Article dans une revue
inserm-00318934v1
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Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors.
Cyril Goudet
,
Florence Gaven
,
Julie Kniazeff
,
Claire Vol
,
Jianfeng Liu
Proceedings of the National Academy of Sciences of the United States of America, 2004, 101 (1), pp.378-83. ⟨10.1073/pnas.0304699101⟩
Article dans une revue
inserm-00319003v1
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Locking the dimeric GABA(B) G-protein-coupled receptor in its active state.
Julie Kniazeff
,
Pierre-Philippe Saintot
,
Cyril Goudet
,
Jianfeng Liu
,
Annie Charnet
Article dans une revue
hal-00319013v1
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Cluster organization and pore structure of ion channels formed by beticolin 3, a nonpeptidic fungal toxin
Cyril Goudet
,
J.P. Benitah
,
M.L. Milat
,
Herve Sentenac
,
J.B. Thibaud
Article dans une revue
hal-02689303v1
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Magnesium ions promote assembly of channel-like structures from beticolin o, a non-peptide fungal toxin purified from Cercospora beticola
Cyril Goudet
,
Anne-Aliénor Véry
,
M.L. Milat
,
M. Ildefonse
,
Jean-Baptiste Thibaud
Article dans une revue
hal-02690441v1
|