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Cynthia Marie-Claire

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Publications

Decreased telomere length in a subgroup of young individuals with bipolar disorders: replication in the FACE-BD cohort and association with the shelterin component POT1

Luana Spano , Cynthia Marie-Claire , Ophélia Godin , Apolline Lebras , Cindie Courtin
Translational Psychiatry, 2024, 14 (1), pp.131. ⟨10.1038/s41398-024-02824-z⟩
Article dans une revue hal-04492634v1
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Risperidone response in patients with schizophrenia drives DNA methylation changes in immune and neuronal systems

Ana Lokmer , Charanraj Goud Alladi , Réjane Troudet , Delphine Bacq-Daian , Anne Boland-Auge
Epigenomics, 2023, ⟨10.2217/epi-2023-0017⟩
Article dans une revue inserm-04044562v1
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Accelerated aging in bipolar disorders: An exploratory study of six epigenetic clocks

Céline Bourdon , Bruno Etain , Luana Spano , Raoul Belzeaux , Marion Leboyer
Psychiatry Research, 2023, 327, pp.115373. ⟨10.1016/j.psychres.2023.115373⟩
Article dans une revue hal-04181925v2
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Telomere length and mitochondrial DNA copy number in bipolar disorder: identification of a subgroup of young individuals with accelerated cellular aging

L. Spano , B. Etain , M. Meyrel , V. Hennion , G. Gross
Translational Psychiatry, 2022, 12 (1), pp.135. ⟨10.1038/s41398-022-01891-4⟩
Article dans une revue hal-03767733v1
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The molecular pathophysiology of mood disorders: From the analysis of single molecular layers to multi-omic integration

Amazigh Mokhtari , Baptiste Porte , Raoul Belzeaux , Bruno Etain , El Cherif Ibrahim
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2022, 116, pp.110520. ⟨10.1016/j.pnpbp.2022.110520⟩
Article dans une revue hal-03568945v1

Plasma tau, NfL, GFAP and UCHL1 as candidate biomarkers of alcohol withdrawal-associated brain damage: A pilot study

Virgile Clergue-Duval , Agathe Vrillon , Jerome Jeanblanc , Frank Questel , Julien Azuar
Addiction Biology, 2022, 27 (6), ⟨10.1111/adb.13232⟩
Article dans une revue hal-03783445v1
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Individual differences in cocaine-induced conditioned place preference in male rats: Behavioral and transcriptomic evidence

Luisa Alessandra Atehortua Martinez , Emmanuel Curis , Nawel Mekdad , Claire Larrieu , Cindie Courtin
Journal of Psychopharmacology, 2022, 36 (10), pp.1161-1175. ⟨10.1177/02698811221123047⟩
Article dans une revue hal-03784427v1
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Biomarkers of Relapse in Cocaine Use Disorder: A Narrative Review

Margaux Poireau , Thomas Milpied , Angéline Maillard , Christine Delmaire , Emmanuelle Volle
Brain Sciences, 2022, 12 (8), pp.1013. ⟨10.3390/brainsci12081013⟩
Article dans une revue hal-03784434v1
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Associations between circadian misalignment and telomere length in BD: an actigraphy study

Luana Spano , Vincent Hennion , Cynthia Marie-Claire , Frank Bellivier , Jan Scott
International Journal of Bipolar Disorders, 2022, 10 (1), pp.14. ⟨10.1186/s40345-022-00260-w⟩
Article dans une revue hal-03767739v1

Telomere length and mitochondrial DNA copy number in bipolar disorder: a sibling study.

L. Spano , B. Etain , J-L Laplanche , M. Leboyer , S. Gard
World Journal of Biological Psychiatry, 2022, pp.1-25. ⟨10.1080/15622975.2022.2131907⟩
Article dans une revue hal-03798566v1
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Methylomic Biomarkers of Lithium Response in Bipolar Disorder: A Proof of Transferability Study

Cynthia Marie-Claire , Cindie Courtin , Frank Bellivier , Jan Scott , Bruno Etain
Pharmaceuticals, 2022, 15 (2), pp.133. ⟨10.3390/ph15020133⟩
Article dans une revue hal-03806366v1
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Transcriptomics and miRNomics data integration in lymphoblastoid cells highlights the key role of immune-related functions in lithium treatment response in Bipolar disorder

Nadia Cattane , Cindie Courtin , Elisa Mombelli , Carlo Maj , Cristina Mora
BMC Psychiatry, 2022, 22 (1), pp.665. ⟨10.1186/s12888-022-04286-3⟩
Article dans une revue hal-03834253v1
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Biomarkers to predict staging and treatment response in opioid dependence: A narrative review

Florence Vorspan , Cynthia Marie-Claire , Frank Bellivier , Vanessa Bloch
Drug Development Research, 2021, ⟨10.1002/ddr.21789⟩
Article dans une revue hal-03123197v1

Network of co-expressed circadian genes, childhood maltreatment and sleep quality in bipolar disorders

D. Grillault Laroche , E. Curis , F. Bellivier , C. Nepost , G. Gross
Chronobiology International, 2021, pp.1-8. ⟨10.1080/07420528.2021.1903028⟩
Article dans une revue hal-03239600v1

Neurobiological and behavioral mechanisms of circadian rhythm disruption in bipolar disorder: A critical multi‐disciplinary literature review and agenda for future research from the ISBD task force on chronobiology

Cynthia Marie-Claire , Diane Grillault Laroche , Ophélia Godin , Raoul Belzeaux , Katia M'Bailara
Bipolar Disorders, 2021, pp.1-32. ⟨10.1111/bdi.13165⟩
Article dans une revue hal-03568951v1
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A Comparison of Different Approaches to Clinical Phenotyping of Lithium Response: A Proof of Principle Study Employing Genetic Variants of Three Candidate Circadian Genes

Jan Scott , Mohamed Lajnef , Romain Icick , Frank Bellivier , Cynthia Marie-Claire
Pharmaceuticals, 2021, 14 (11), pp.1072. ⟨10.3390/ph14111072⟩
Article dans une revue hal-03568955v1
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Clinical Trials of Cannabidiol for Substance Use Disorders: Outcome Measures, Surrogate Endpoints, and Biomarkers

Alix Morel , Pierre Lebard , Alexandra Dereux , Julien Azuar , Frank Questel
Frontiers in Psychiatry, 2021, 12, pp.565617. ⟨10.3389/fpsyt.2021.565617⟩
Article dans une revue hal-03239604v1
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Clustering suicidal phenotypes and genetic associations with brain-derived neurotrophic factor in patients with substance use disorders

Romain Icick , Vanessa Bloch , Nathalie Prince , Emily Karsinti , Jean-Pierre Lépine
Translational Psychiatry, 2021, 11 (1), pp.72. ⟨10.1038/s41398-021-01200-5⟩
Article dans une revue hal-03123199v1
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Neurobiological and behavioral mechanisms of circadian rhythm disruption in bipolar disorder: A critical multi‐disciplinary literature review and agenda for future research from the ISBD task force on chronobiology

Michael Mccarthy , John Gottlieb , Robert Gonzalez , Colleen Mcclung , Lauren Alloy
Bipolar Disorders, 2021, 24 (3), pp.232-263. ⟨10.1111/bdi.13165⟩
Article dans une revue hal-03806382v1
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Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients

Cynthia Marie-Claire , Klaus Oliver Schubert , Anbupalam Thalamuthu , Azmeraw Amare , Joseph Frank
Translational Psychiatry, 2021, 11 (1), pp.606. ⟨10.1038/s41398-021-01702-2⟩
Article dans une revue hal-03568953v1
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Mini review: Recent advances on epigenetic effects of lithium

Cynthia Marie-Claire , B. Etain , F. Bellivier
Neuroscience Letters, 2021, 761, pp.136116. ⟨10.1016/j.neulet.2021.136116⟩
Article dans une revue hal-03357149v1
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A DNA methylation signature discriminates between excellent and non-response to lithium in patients with bipolar disorder type 1

Cynthia Marie-Claire , François-Xavier Lejeune , Emeline Mundwiller , Damien Ulveling , Ivan Moszer
Scientific Reports, 2020, 10 (1), pp.12239. ⟨10.1038/s41598-020-69073-0⟩
Article dans une revue inserm-02937821v1
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Translational study of the whole transcriptome in rats and genetic polymorphisms in humans identifies LRP1B and VPS13A as key genes involved in tolerance to cocaine-induced motor disturbances.

Florence Vorspan , Romain Icick , Nawel Mekdad , Cindie Courtin , Vanessa Bloch
Translational Psychiatry, 2020, 10 (1), pp.381. ⟨10.1038/s41398-020-01050-7⟩
Article dans une revue hal-03024249v1
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Childhood maltreatment and HPA axis gene expression in bipolar disorders: A gene network analysis.

D Grillault Laroche , E Curis , F Bellivier , C Nepost , Cindie Courtin
Psychoneuroendocrinology, 2020, 120, pp.104753. ⟨10.1016/j.psyneuen.2020.104753⟩
Article dans une revue hal-03024265v1
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Translational study of the whole transcriptome in rats and genetic polymorphisms in humans identifies LRP1B and VPS13A as key genes involved in tolerance to cocaine-induced motor disturbances

Florence Vorspan , Romain Icick , Nawel Mekdad , Cindie Courtin , Vanessa Bloch
Translational Psychiatry, 2020, 10 (1), pp.381. ⟨10.1038/s41398-020-01050-7⟩
Article dans une revue hal-03893616v1
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Selecting reference genes in RT-qPCR based on equivalence tests: a network based approach

Emmanuel Curis , Calypso Nepost , Diane Grillault Laroche , Cindie Courtin , Jean-Louis Laplanche
Scientific Reports, 2019, 9 (1), pp.16231. ⟨10.1038/s41598-019-52217-2⟩
Article dans une revue hal-03032928v1
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QT length during methadone maintenance treatment: gene × dose interaction

El-Hadi Zerdazi , Florence Vorspan , Andries Marees , François Naccache , Jean-Pierre Lepine
Fundamental & Clinical Pharmacology, 2019, 33 (1), pp.96 - 106. ⟨10.1111/fcp.12405⟩
Article dans une revue hal-03032957v1
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Increased plasma levels of high mobility group box 1 protein in patients with bipolar disorder: A pilot study

Cynthia Marie-Claire , Cindie Courtin , Emmanuel Curis , Elodie Bouaziz-Amar , Jean-Louis Laplanche
Journal of Neuroimmunology, 2019, 334, pp.576993. ⟨10.1016/j.jneuroim.2019.576993⟩
Article dans une revue hal-02335130v1
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Selecting reference genes in RT-qPCR based on equivalence tests: a network based approach

Emmanuel Curis , Calypso Nepost , Diane Grillault Laroche , Cindie Courtin , Jean-Louis Laplanche
Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-52217-2⟩
Article dans une revue hal-02355149v1
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Determination of sets of covariating gene expression using graph analysis on pairwise expression ratios

Emmanuel Curis , Cindie Courtin , Pierre Alexis Geoffroy , Jean-Louis Laplanche , Bruno Saubamea
Article dans une revue hal-01904746v1

Dopamine ( DRD2 ) and Serotonin ( HTR2A, 2C) Receptor Gene Polymorphisms do not influence early response to Risperidone in South Indian Patients with Schizophrenia

Charanraj Goud Alladi , Ravi Philip Rajkumar , Surendiran Adithan , Cynthia Marie-Claire , Frank Bellivier
Fundamental & Clinical Pharmacology, inPress, ⟨10.1111/fcp.12424⟩
Article dans une revue hal-01904725v1
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Determination of sets of covariating gene expression using graph analysis on pairwise expression ratios

Emmanuel Curis , Cindie Courtin , Pierre Alexis Geoffroy , Jean-Louis Laplanche , Bruno Saubaméa
Bioinformatics, 2018, 35, pp.258 - 265. ⟨10.1093/bioinformatics/bty629⟩
Article dans une revue hal-03033388v1

Lithium effects on serine-threonine kinases activity: High throughput kinomic profiling of lymphoblastoid cell lines from excellent-responders and non-responders bipolar patients

Jeverson Moreira , Gaëlle Noé , Savithri Rangarajan , Cindie Courtin , Bruno Etain
World Journal of Biological Psychiatry, 2018, pp.1 - 8. ⟨10.1080/15622975.2018.1487078⟩
Article dans une revue hal-01904750v1
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QT length during methadone maintenance treatment: Gene x dose interaction

El-Hadi Zerdazi , Florence Vorspan , Andries Marees , François Naccache , Jean-Pierre Lépine
Fundamental & Clinical Pharmacology, 2018, 33 (1), pp.96-106. ⟨10.1111/fcp.12405⟩
Article dans une revue hal-01904739v1

A tutorial on conducting genome-wide association studies: Quality control and statistical analysis

Andries Marees , Hilde de Kluiver , Sven Stringer , Florence Vorspan , Emmanuel Curis
International Journal of Methods in Psychiatric Research, 2018, 27 (2), ⟨10.1002/mpr.1608⟩
Article dans une revue hal-01904753v1
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Dopamine ( DRD 2 ) and Serotonin ( HTR 2A, 2C) Receptor Gene Polymorphisms do not influence early response to Risperidone in South Indian Patients with Schizophrenia

Charanraj Goud Alladi , Ravi Philip Rajkumar , Surendiran Adithan , Cynthia Marie-Claire , Frank Bellivier
Fundamental & Clinical Pharmacology, 2018, 33, pp.355 - 364. ⟨10.1111/fcp.12424⟩
Article dans une revue hal-03032951v1

Molecular Signatures of Lithium Treatment: Current Knowledge

Frank Bellivier , Cynthia Marie-Claire
Pharmacopsychiatry, 2018, 51 (05), pp.212 - 219. ⟨10.1055/a-0650-4820⟩
Article dans une revue hal-01904742v1

DNA Methylation as a Biomarker of Treatment Response Variability in Serious Mental Illnesses: A Systematic Review Focused on Bipolar Disorder, Schizophrenia, and Major Depressive Disorder

Charanraj Goud Alladi , Bruno Etain , Frank Bellivier , Cynthia Marie-Claire
International Journal of Molecular Sciences, 2018, 19 (10), ⟨10.3390/ijms19103026⟩
Article dans une revue hal-01904730v1

Pharmacoepigenomics of opiates and methadone maintenance treatment: current data and perspectives

Cynthia Marie-Claire , Clément Jourdaine , Jean-Pierre Lépine , Frank Bellivier , Vanessa Bloch
Pharmacogenomics, 2017, 18 (14), pp.1359 - 1372. ⟨10.2217/pgs-2017-0040⟩
Article dans une revue hal-01904755v1

Lithium response in bipolar disorder: No difference in GADL1 gene expression between cell lines from excellent-responders and non-responders

Cynthia Marie-Claire , Jeverson Moreira , Cindie Courtin , Pierre Alexis Geoffroy , Emmanuel Curis
Psychiatry Research, 2017, 251, pp.217 - 220. ⟨10.1016/j.psychres.2017.02.022⟩
Article dans une revue hal-01904761v1

Lithium response in bipolar disorders and core clock genes expression

Pierre Alexis Geoffroy , Emmanuel Curis , Cindie Courtin , Jeverson Moreira , Thomas Morvillers
World Journal of Biological Psychiatry, 2017, pp.1 - 14. ⟨10.1080/15622975.2017.1282174⟩
Article dans une revue hal-01904765v1

Circadian genes and lithium response in bipolar disorders: associations with PPARGC1A (PGC-1 α ) and RORA

P. A. Geoffroy , B. Etain , M. Lajnef , E. H. Zerdazi , C. Brichant-Petitjean
Genes, Brain and Behavior, 2016, 15 (7), pp.660 - 668. ⟨10.1111/gbb.12306⟩
Article dans une revue hal-01904767v1
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Variability of response to methadone: genome-wide DNA methylation analysis in two independent cohorts

Cynthia Marie-Claire , Severine Crettol , Nicolas Cagnard , Vanessa Bloch , Stéphane Mouly
Epigenomics, 2016, 8 (2), pp.181 - 195. ⟨10.2217/epi.15.110⟩
Article dans une revue hal-01904769v1
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Impact of P-glycoprotein at the blood-brain barrier on the uptake of heroin and its main metabolites: behavioral effects and consequences on the transcriptional responses and reinforcing properties

Maria Seleman , Hélène Chapy , Salvatore Cisternino , Cindie Courtin , Maria Smirnova
Psychopharmacology, 2014, 231 (16), pp.3139 - 3149. ⟨10.1007/s00213-014-3490-9⟩
Article dans une revue hal-01904771v1
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Comparison of the transcriptional responses induced by acute morphine, methadone and buprenorphine

Emilie Belkaï , Dominique Crété , Cindie Courtin , Florence Noble , Cynthia Marie-Claire
European Journal of Pharmacology, 2013, 711 (1-3), pp.10-18. ⟨10.1016/j.ejphar.2013.04.015⟩
Article dans une revue hal-01904772v1

Transport of Biogenic Amine Neurotransmitters at the Mouse Blood–Retina and Blood–Brain Barriers by Uptake1 and Uptake2

Pascal André , Bruno Saubamea , Véronique Cochois-Guégan , Cynthia Marie-Claire , Julie Cattelotte
Journal of Cerebral Blood Flow and Metabolism, 2012, 32 (11), pp.1989 - 2001. ⟨10.1038/jcbfm.2012.109⟩
Article dans une revue hal-01904808v1

Chronic and intermittent morphine treatment differently regulates opioid and dopamine systems: a role in locomotor sensitization

Cynthia Marie-Claire , Thierry Le Marec , Cynthia Marie , Florence Noble , Nicolas Marie
Psychopharmacology, 2011, 216 (2), pp.297 - 303. ⟨10.1007/s00213-011-2223-6⟩
Article dans une revue hal-01905192v1
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Modulation of MDMA-induced behavioral and transcriptional effects by the delta opioid antagonist naltrindole in mice.

Emilie Belkaï , Jean-Michel Scherrmann , Florence Noble , Cynthia Marie-Claire
Addiction Biology, 2009, 14 (3), pp.245-52. ⟨10.1111/j.1369-1600.2009.00156.x⟩
Article dans une revue inserm-00416565v1
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Involvement of D1 dopamine receptor in MDMA-induced locomotor activity and striatal gene expression in mice.

Nadia Benturquia , Cindie Courtin , Florence Noble , Cynthia Marie-Claire
Brain Research, 2008, 1211, pp.1-5. ⟨10.1016/j.brainres.2008.03.016⟩
Article dans une revue inserm-00279098v1
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Effects of the selective neurotensin antagonist SR 142948A on 3,4-methylenedioxymethamphetamine-induced behaviours in mice.

Cynthia Marie-Claire , Stefano Palminteri , Patrizia Romualdi , Florence Noble
Neuropharmacology, 2008, 54 (7), pp.1107-11. ⟨10.1016/j.neuropharm.2008.03.001⟩
Article dans une revue inserm-00278426v1

Effects of chronic morphine and morphine withdrawal on gene expression in rat peripheral blood mononuclear cells

Stephane Desjardins , Emilie Belkai , Dominique Crete , Laurie Cordonnier , Jean-Michel Scherrmann
Neuropharmacology, 2008, 55 (8), pp.1347 - 1354. ⟨10.1016/j.neuropharm.2008.08.027⟩
Article dans une revue hal-01905201v1
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Effects of chronic morphine and morphine withdrawal on gene expression in rat peripheral blood mononuclear cells.

Stephane Desjardins , Emilie Belkai , Dominique Crete , Laurie Cordonnier , Jean-Michel Scherrmann
Neuropharmacology, 2008, 55 (8), pp.1347-54. ⟨10.1016/j.neuropharm.2008.08.027⟩
Article dans une revue inserm-00343477v1
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Expression of drug transporters at the blood-brain barrier using an optimized isolated rat brain microvessel strategy.

Salah Yousif , Cynthia Marie-Claire , Françoise Roux , Jean-Michel Scherrmann , Xavier Declèves
Brain Research, 2007, 1134 (1), pp.1-11. ⟨10.1016/j.brainres.2006.11.089⟩
Article dans une revue inserm-00176175v1
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Rnd family genes are differentially regulated by 3,4-methylenedioxymethamphetamine and cocaine acute treatment in mice brain.

Cynthia Marie-Claire , Julie Salzmann , Alexandre David , Cindie Courtin , Corinne Canestrelli
Brain Research, 2007, 1134 (1), pp.12-7. ⟨10.1016/j.brainres.2006.11.065⟩
Article dans une revue inserm-00193078v1
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Sensitization to the conditioned rewarding effects of morphine modulates gene expression in rat hippocampus.

Cynthia Marie-Claire , Cindie Courtin , Amelie Robert , Xavier Gidrol , Bernard P. Roques
Neuropharmacology, 2007, 52 (2), pp.430-5. ⟨10.1016/j.neuropharm.2006.08.012⟩
Article dans une revue inserm-00162324v1
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Regulation of genes involved in dopamine transporter modulation by acute cocaine in rat striatum.

Cindie Courtin , Dominique Crete , Corinne Canestrelli , Florence Noble , Cynthia Marie-Claire
Neuroscience Letters, 2006, 398 (3), pp.235-40. ⟨10.1016/j.neulet.2006.01.001⟩
Article dans une revue inserm-00162388v1
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Analysis of transcriptional responses in the mouse dorsal striatum following acute 3,4-methylenedioxymethamphetamine (ecstasy): identification of extracellular signal-regulated kinase-controlled genes.

Julie Salzmann , Corinne Canestrelli , Florence Noble , Cynthia Marie-Claire
Neuroscience, 2006, 137 (2), pp.473-82. ⟨10.1016/j.neuroscience.2005.09.019⟩
Article dans une revue inserm-00171007v1
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Cytoskeletal genes regulation by chronic morphine treatment in rat striatum.

Cynthia Marie-Claire , Cindie Courtin , Bernard P. Roques , Florence Noble
Neuropsychopharmacology, 2004, 29 (12), pp.2208-15. ⟨10.1038/sj.npp.1300513⟩
Article dans une revue inserm-00144800v1
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[Acute and long-term effects of ecstasy]

Julie Salzmann , Cynthia Marie-Claire , Florence Noble
La Presse Médicale, 2004, 33 (18 Suppl), pp.24-32
Article dans une revue inserm-00176174v1
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Importance of ERK activation in behavioral and biochemical effects induced by MDMA in mice.

Julie Salzmann , Cynthia Marie-Claire , Stephanie Le Guen , Bernard P Roques , Florence Noble
British Journal of Pharmacology, 2003, 140 (5), pp.831-8. ⟨10.1038/sj.bjp.0705506⟩
Article dans une revue inserm-00171261v1
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Further evidence that the CCK2 receptor is coupled to two transduction pathways using site-directed mutagenesis.

Blandine Pommier , Cynthia Marie-Claire , Sophie da Nascimento , Hung-Li Wang , Bernard P. Roques
Journal of Neurochemistry, 2003, 85 (2), pp.454-61
Article dans une revue inserm-00171259v1
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Fos but not Cart (cocaine and amphetamine regulated transcript) is overexpressed by several drugs of abuse: a comparative study using real-time quantitative polymerase chain reaction in rat brain.

Cynthia Marie-Claire , Ingrid Laurendeau , Corine Canestrelli , Cindie Courtin , Michel Vidaud
Neuroscience Letters, 2003, 345 (2), pp.77-80
Article dans une revue inserm-00171266v1
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General function of N-terminal propeptide on assisting protein folding and inhibiting catalytic activity based on observations with a chimeric thermolysin-like protease.

Bing Tang , Satoru Nirasawa , Motomitsu Kitaoka , Cynthia Marie-Claire , Kiyoshi Hayashi
Biochemical and Biophysical Research Communications, 2003, 301 (4), pp.1093-8
Article dans une revue inserm-00144798v1
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Folding pathway mediated by an intramolecular chaperone: the structural and functional characterization of the aqualysin I propeptide.

Cynthia Marie-Claire , Yukihiro Yabuta , Kyoko Suefuji , Hiroshi Matsuzawa , Ujwal Shinde
Journal of Molecular Biology, 2001, 305 (1), pp.151-65. ⟨10.1006/jmbi.2000.4233⟩
Article dans une revue inserm-00171014v1
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Exploration of the S'1 subsite of neprilysin: a joined molecular modeling and site-directed mutagenesis study.

Cynthia Marie-Claire , Gilles Tiraboschi , Emmanuel Ruffet , Nicolas Inguimbert , Marie-Claude Fournie-Zaluski
Proteins - Structure, Function and Bioinformatics, 2000, 39 (4), pp.365-71
Article dans une revue inserm-00171018v1
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The prosequence of thermolysin acts as an intramolecular chaperone when expressed in trans with the mature sequence in Escherichia coli.

Cynthia Marie-Claire , Emmanuel Ruffet , Ann Beaumont , Bernard P. Roques
Journal of Molecular Biology, 1999, 285 (5), pp.1911-5. ⟨10.1006/jmbi.1998.2449⟩
Article dans une revue inserm-00171255v1
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Characterization of Glu350 as a critical residue involved in the N-terminal amine binding site of aminopeptidase N (EC 3.4.11.2): insights into its mechanism of action.

Nathalie Luciani , Cynthia Marie-Claire , Emmanuel Ruffet , Ann Beaumont , Bernard P. Roques
Biochemistry, 1998, 37 (2), pp.686-92. ⟨10.1021/bi971705p⟩
Article dans une revue inserm-00145193v1
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Differences in transition state stabilization between thermolysin (EC 3.4.24.27) and neprilysin (EC 3.4.24.11).

Cynthia Marie-Claire , Emmanuel Ruffet , Gilles Tiraboschi , Marie-Claude Fournie-Zaluski
FEBS Letters, 1998, 438 (3), pp.215-9
Article dans une revue inserm-00145191v1
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Intramolecular processing of prothermolysin.

Cynthia Marie-Claire , Bernard P. Roques , Ann Beaumont
Journal of Biological Chemistry, 1998, 273 (10), pp.5697-701
Article dans une revue inserm-00145189v1
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Evidence by site-directed mutagenesis that arginine 203 of thermolysin and arginine 717 of neprilysin (neutral endopeptidase) play equivalent critical roles in substrate hydrolysis and inhibitor binding.

Cynthia Marie-Claire , Emmanuel Ruffet , Serge Antonczak , Ann Beaumont , Michael O'Donohue
Biochemistry, 1997, 36 (45), pp.13938-45. ⟨10.1021/bi9712495⟩
Article dans une revue inserm-00171023v1