Cynthia Marie-Claire

Cynthia Marie-Claire, Amazigh Mokhtari, Baptiste Porte, Raoul Belzeaux, Bruno Etain, et al.. The molecular pathophysiology of mood disorders: From the analysis of single molecular layers to multi-omic integration. Progress in Neuro-Psychopharmacology and Biological Psychiatry, Elsevier, 2022, 116, pp.110520. ⟨10.1016/j.pnpbp.2022.110520⟩. ⟨hal-03568945⟩

Cynthia Marie-Claire, B. Etain, F. Bellivier. Mini review: Recent advances on epigenetic effects of lithium. Neuroscience Letters, 2021, 761, pp.136116. ⟨10.1016/j.neulet.2021.136116⟩. ⟨hal-03357149⟩

Florence Vorspan, Cynthia Marie-Claire, Frank Bellivier, Vanessa Bloch, Cynthia Marie‐claire. Biomarkers to predict staging and treatment response in opioid dependence: A narrative review. Drug Development Research, Wiley, 2021, ⟨10.1002/ddr.21789⟩. ⟨hal-03123197⟩

D. Grillault Laroche, E. Curis, F. Bellivier, C. Nepost, G. Gross, et al.. Network of co-expressed circadian genes, childhood maltreatment and sleep quality in bipolar disorders. Chronobiology International, Taylor & Francis, 2021, pp.1-8. ⟨10.1080/07420528.2021.1903028⟩. ⟨hal-03239600⟩

Cynthia Marie-Claire, Jan Scott, Mohamed Lajnef, Romain Icick, Frank Bellivier, et al.. A Comparison of Different Approaches to Clinical Phenotyping of Lithium Response: A Proof of Principle Study Employing Genetic Variants of Three Candidate Circadian Genes. Pharmaceuticals, MDPI, 2021, 14 (11), pp.1072. ⟨10.3390/ph14111072⟩. ⟨hal-03568955⟩

Cynthia Marie-Claire, Klaus Oliver Schubert, Anbupalam Thalamuthu, Azmeraw Amare, Joseph Frank, et al.. Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients. Translational Psychiatry, Nature Pub. Group, 2021, 11 (1), pp.606. ⟨10.1038/s41398-021-01702-2⟩. ⟨hal-03568953⟩

Cynthia Marie-Claire, Diane Grillault Laroche, Ophélia Godin, Raoul Belzeaux, Katia M'Bailara, et al.. Neurobiological and behavioral mechanisms of circadian rhythm disruption in bipolar disorder: A critical multi‐disciplinary literature review and agenda for future research from the ISBD task force on chronobiology. Bipolar Disorders, Wiley, 2021, pp.1-32. ⟨10.1111/bdi.13165⟩. ⟨hal-03568951⟩

Romain Icick, Vanessa Bloch, Nathalie Prince, Emily Karsinti, Jean-Pierre Lépine, et al.. Clustering suicidal phenotypes and genetic associations with brain-derived neurotrophic factor in patients with substance use disorders. Translational Psychiatry, Nature Pub. Group, 2021, 11 (1), pp.72. ⟨10.1038/s41398-021-01200-5⟩. ⟨hal-03123199⟩

Alix Morel, Pierre Lebard, Alexandra Dereux, Julien Azuar, Frank Questel, et al.. Clinical Trials of Cannabidiol for Substance Use Disorders: Outcome Measures, Surrogate Endpoints, and Biomarkers. Frontiers in Psychiatry, Frontiers, 2021, 12, pp.565617. ⟨10.3389/fpsyt.2021.565617⟩. ⟨hal-03239604⟩

Florence Vorspan, Romain Icick, Nawel Mekdad, Cindie Courtin, Vanessa Bloch, et al.. Translational study of the whole transcriptome in rats and genetic polymorphisms in humans identifies LRP1B and VPS13A as key genes involved in tolerance to cocaine-induced motor disturbances.. Translational Psychiatry, Nature Pub. Group, 2020, 10 (1), pp.381. ⟨10.1038/s41398-020-01050-7⟩. ⟨hal-03024249⟩

Cynthia Marie-Claire, F Lejeune, E Mundwiller, D Ulveling, I Moszer, et al.. A DNA methylation signature discriminates between excellent and non-response to lithium in patients with bipolar disorder type 1.. Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.12239. ⟨10.1038/s41598-020-69073-0⟩. ⟨hal-03024260⟩

Cynthia Marie-Claire, François-Xavier Lejeune, Emeline Mundwiller, Damien Ulveling, Ivan Moszer, et al.. A DNA methylation signature discriminates between excellent and non-response to lithium in patients with bipolar disorder type 1. Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.12239. ⟨10.1038/s41598-020-69073-0⟩. ⟨inserm-02937821⟩

Emmanuel Curis, Calypso Nepost, Diane Grillault Laroche, Cindie Courtin, Jean-Louis Laplanche, et al.. Selecting reference genes in RT-qPCR based on equivalence tests: a network based approach. Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-52217-2⟩. ⟨hal-02355149⟩

Emmanuel Curis, Calypso Nepost, Diane Grillault Laroche, Cindie Courtin, Jean-Louis Laplanche, et al.. Selecting reference genes in RT-qPCR based on equivalence tests: a network based approach. Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.16231. ⟨10.1038/s41598-019-52217-2⟩. ⟨hal-03032928⟩

Cynthia Marie-Claire, Cindie Courtin, Emmanuel Curis, Elodie Bouaziz-Amar, Jean-Louis Laplanche, et al.. Increased plasma levels of high mobility group box 1 protein in patients with bipolar disorder: A pilot study. Journal of Neuroimmunology, Elsevier, 2019, 334, pp.576993. ⟨10.1016/j.jneuroim.2019.576993⟩. ⟨hal-02335130⟩

El-Hadi Zerdazi, Florence Vorspan, Andries Marees, François Naccache, Jean-Pierre Lepine, et al.. QT length during methadone maintenance treatment: gene × dose interaction. Fundamental and Clinical Pharmacology, Wiley, 2019, 33 (1), pp.96 - 106. ⟨10.1111/fcp.12405⟩. ⟨hal-03032957⟩

Jeverson Moreira, Gaëlle Noé, Savithri Rangarajan, Cindie Courtin, Bruno Etain, et al.. Lithium effects on serine-threonine kinases activity: High throughput kinomic profiling of lymphoblastoid cell lines from excellent-responders and non-responders bipolar patients. World Journal of Biological Psychiatry, Taylor & Francis, 2018, pp.1 - 8. ⟨10.1080/15622975.2018.1487078⟩. ⟨hal-01904750⟩

Emmanuel Curis, Cindie Courtin, Pierre Alexis Geoffroy, Jean-Louis Laplanche, Bruno Saubamea, et al.. Determination of sets of covariating gene expression using graph analysis on pairwise expression ratios. Bioinformatics, Oxford University Press (OUP), 2018, ⟨10.1093/bioinformatics/bty629⟩. ⟨hal-01904746⟩

Charanraj Goud Alladi, Bruno Etain, Frank Bellivier, Cynthia Marie-Claire. DNA Methylation as a Biomarker of Treatment Response Variability in Serious Mental Illnesses: A Systematic Review Focused on Bipolar Disorder, Schizophrenia, and Major Depressive Disorder. International Journal of Molecular Sciences, MDPI, 2018, 19 (10), ⟨10.3390/ijms19103026⟩. ⟨hal-01904730⟩

Andries Marees, Hilde de Kluiver, Sven Stringer, Florence Vorspan, Emmanuel Curis, et al.. A tutorial on conducting genome-wide association studies: Quality control and statistical analysis. International Journal of Methods in Psychiatric Research, Wiley, 2018, 27 (2), ⟨10.1002/mpr.1608⟩. ⟨hal-01904753⟩

Charanraj Goud Alladi, Ravi Philip Rajkumar, Surendiran Adithan, Cynthia Marie-Claire, Frank Bellivier, et al.. Dopamine ( DRD2 ) and Serotonin ( HTR2A, 2C) Receptor Gene Polymorphisms do not influence early response to Risperidone in South Indian Patients with Schizophrenia. Fundamental and Clinical Pharmacology, Wiley, In press, ⟨10.1111/fcp.12424⟩. ⟨hal-01904725⟩

El-Hadi Zerdazi, Florence Vorspan, Andries Marees, François Naccache, Jean-Pierre Lépine, et al.. QT length during methadone maintenance treatment: Gene x dose interaction. Fundamental and Clinical Pharmacology, Wiley, 2018, ⟨10.1111/fcp.12405⟩. ⟨hal-01904739⟩

Charanraj Goud Alladi, Ravi Philip Rajkumar, Surendiran Adithan, Cynthia Marie-Claire, Frank Bellivier, et al.. Dopamine ( DRD 2 ) and Serotonin ( HTR 2A, 2C) Receptor Gene Polymorphisms do not influence early response to Risperidone in South Indian Patients with Schizophrenia. Fundamental and Clinical Pharmacology, Wiley, 2018, 33, pp.355 - 364. ⟨10.1111/fcp.12424⟩. ⟨hal-03032951⟩

Frank Bellivier, Cynthia Marie-Claire. Molecular Signatures of Lithium Treatment: Current Knowledge. Pharmacopsychiatry, Georg Thieme Verlag, 2018, 51 (05), pp.212 - 219. ⟨10.1055/a-0650-4820⟩. ⟨hal-01904742⟩

Emmanuel Curis, Cindie Courtin, Pierre Alexis Geoffroy, Jean-Louis Laplanche, Bruno Saubaméa, et al.. Determination of sets of covariating gene expression using graph analysis on pairwise expression ratios. Bioinformatics, Oxford University Press (OUP), 2018, 35, pp.258 - 265. ⟨10.1093/bioinformatics/bty629⟩. ⟨hal-03033388⟩

Pierre Geoffroy, Emmanuel Curis, Cindie Courtin, Jeverson Moreira, Thomas Morvillers, et al.. Lithium response in bipolar disorders and core clock genes expression. World Journal of Biological Psychiatry, Taylor & Francis, 2017, pp.1 - 14. ⟨10.1080/15622975.2017.1282174⟩. ⟨hal-01904765⟩

Cynthia Marie-Claire, Jeverson Moreira, Cindie Courtin, Pierre Geoffroy, Emmanuel Curis, et al.. Lithium response in bipolar disorder: No difference in GADL1 gene expression between cell lines from excellent-responders and non-responders. Psychiatry Research, Elsevier, 2017, 251, pp.217 - 220. ⟨10.1016/j.psychres.2017.02.022⟩. ⟨hal-01904761⟩

Cynthia Marie-Claire, Clément Jourdaine, Jean-Pierre Lépine, Frank Bellivier, Vanessa Bloch, et al.. Pharmacoepigenomics of opiates and methadone maintenance treatment: current data and perspectives. Pharmacogenomics, Future Medicine, 2017, 18 (14), pp.1359 - 1372. ⟨10.2217/pgs-2017-0040⟩. ⟨hal-01904755⟩

Cynthia Marie-Claire, Severine Crettol, Nicolas Cagnard, Vanessa Bloch, Stéphane Mouly, et al.. Variability of response to methadone: genome-wide DNA methylation analysis in two independent cohorts. Epigenomics, Future Medicine, 2016, 8 (2), pp.181 - 195. ⟨10.2217/epi.15.110⟩. ⟨hal-01904769⟩

P. A. Geoffroy, B. Etain, M. Lajnef, E. H. Zerdazi, C. Brichant-Petitjean, et al.. Circadian genes and lithium response in bipolar disorders: associations with PPARGC1A (PGC-1 α ) and RORA. Genes, Brain and Behavior, Wiley, 2016, 15 (7), pp.660 - 668. ⟨10.1111/gbb.12306⟩. ⟨hal-01904767⟩

Maria Seleman, Hélène Chapy, Salvatore Cisternino, Cindie Courtin, Maria Smirnova, et al.. Impact of P-glycoprotein at the blood-brain barrier on the uptake of heroin and its main metabolites: behavioral effects and consequences on the transcriptional responses and reinforcing properties. Psychopharmacology, Springer Verlag, 2014, 231 (16), pp.3139 - 3149. ⟨10.1007/s00213-014-3490-9⟩. ⟨hal-01904771⟩

Emilie Belkai, Dominique Crete, Cindie Courtin, Florence Noble, Cynthia Marie-Claire. Comparison of the transcriptional responses induced by acute morphine, methadone and buprenorphine. European Journal of Pharmacology, Elsevier, 2013, 711 (1-3), pp.10 - 18. ⟨10.1016/j.ejphar.2013.04.015⟩. ⟨hal-01904772⟩

Pascal André, Bruno Saubamea, Véronique Cochois-Guégan, Cynthia Marie-Claire, Julie Cattelotte, et al.. Transport of Biogenic Amine Neurotransmitters at the Mouse Blood–Retina and Blood–Brain Barriers by Uptake1 and Uptake2. Journal of Cerebral Blood Flow and Metabolism, Nature Publishing Group, 2012, 32 (11), pp.1989 - 2001. ⟨10.1038/jcbfm.2012.109⟩. ⟨hal-01904808⟩

Cynthia Marie-Claire, Thierry Le Marec, Cynthia Marie, Florence Noble, Nicolas Marie. Chronic and intermittent morphine treatment differently regulates opioid and dopamine systems: a role in locomotor sensitization. Psychopharmacology, Springer Verlag, 2011, 216 (2), pp.297 - 303. ⟨10.1007/s00213-011-2223-6⟩. ⟨hal-01905192⟩

Emilie Belkaï, Jean-Michel Scherrmann, Florence Noble, Cynthia Marie-Claire. Modulation of MDMA-induced behavioral and transcriptional effects by the delta opioid antagonist naltrindole in mice.. Addiction Biology, Wiley, 2009, 14 (3), pp.245-52. ⟨10.1111/j.1369-1600.2009.00156.x⟩. ⟨inserm-00416565⟩

Stephane Desjardins, Emilie Belkai, Dominique Crete, Laurie Cordonnier, Jean-Michel Scherrmann, et al.. Effects of chronic morphine and morphine withdrawal on gene expression in rat peripheral blood mononuclear cells.. Neuropharmacology, Elsevier, 2008, 55 (8), pp.1347-54. ⟨10.1016/j.neuropharm.2008.08.027⟩. ⟨inserm-00343477⟩

Cynthia Marie-Claire, Stefano Palminteri, Patrizia Romualdi, Florence Noble. Effects of the selective neurotensin antagonist SR 142948A on 3,4-methylenedioxymethamphetamine-induced behaviours in mice.. Neuropharmacology, Elsevier, 2008, 54 (7), pp.1107-11. ⟨10.1016/j.neuropharm.2008.03.001⟩. ⟨inserm-00278426⟩

Stephane Desjardins, Emilie Belkai, Dominique Crete, Laurie Cordonnier, Jean-Michel Scherrmann, et al.. Effects of chronic morphine and morphine withdrawal on gene expression in rat peripheral blood mononuclear cells. Neuropharmacology, Elsevier, 2008, 55 (8), pp.1347 - 1354. ⟨10.1016/j.neuropharm.2008.08.027⟩. ⟨hal-01905201⟩

Nadia Benturquia, Cindie Courtin, Florence Noble, Cynthia Marie-Claire. Involvement of D1 dopamine receptor in MDMA-induced locomotor activity and striatal gene expression in mice.. Brain Research, Elsevier, 2008, 1211, pp.1-5. ⟨10.1016/j.brainres.2008.03.016⟩. ⟨inserm-00279098⟩

Salah Yousif, Cynthia Marie-Claire, Françoise Roux, Jean-Michel Scherrmann, Xavier Declèves. Expression of drug transporters at the blood-brain barrier using an optimized isolated rat brain microvessel strategy.. Brain Research, Elsevier, 2007, 1134 (1), pp.1-11. ⟨10.1016/j.brainres.2006.11.089⟩. ⟨inserm-00176175⟩

Cynthia Marie-Claire, Julie Salzmann, Alexandre David, Cindie Courtin, Corinne Canestrelli, et al.. Rnd family genes are differentially regulated by 3,4-methylenedioxymethamphetamine and cocaine acute treatment in mice brain.. Brain Research, Elsevier, 2007, 1134 (1), pp.12-7. ⟨10.1016/j.brainres.2006.11.065⟩. ⟨inserm-00193078⟩

Cynthia Marie-Claire, Cindie Courtin, Amelie Robert, Xavier Gidrol, Bernard Roques, et al.. Sensitization to the conditioned rewarding effects of morphine modulates gene expression in rat hippocampus.. Neuropharmacology, Elsevier, 2007, 52 (2), pp.430-5. ⟨10.1016/j.neuropharm.2006.08.012⟩. ⟨inserm-00162324⟩

Julie Salzmann, Corinne Canestrelli, Florence Noble, Cynthia Marie-Claire. Analysis of transcriptional responses in the mouse dorsal striatum following acute 3,4-methylenedioxymethamphetamine (ecstasy): identification of extracellular signal-regulated kinase-controlled genes.. Neuroscience, Elsevier - International Brain Research Organization, 2006, 137 (2), pp.473-82. ⟨10.1016/j.neuroscience.2005.09.019⟩. ⟨inserm-00171007⟩

Cindie Courtin, Dominique Crete, Corinne Canestrelli, Florence Noble, Cynthia Marie-Claire. Regulation of genes involved in dopamine transporter modulation by acute cocaine in rat striatum.. Neuroscience Letters, Elsevier, 2006, 398 (3), pp.235-40. ⟨10.1016/j.neulet.2006.01.001⟩. ⟨inserm-00162388⟩

Julie Salzmann, Cynthia Marie-Claire, Florence Noble. [Acute and long-term effects of ecstasy]. La Presse Médicale, Elsevier Masson, 2004, 33 (18 Suppl), pp.24-32. ⟨inserm-00176174⟩

Cynthia Marie-Claire, Cindie Courtin, Bernard Roques, Florence Noble. Cytoskeletal genes regulation by chronic morphine treatment in rat striatum.. Neuropsychopharmacology, Nature Publishing Group, 2004, 29 (12), pp.2208-15. ⟨10.1038/sj.npp.1300513⟩. ⟨inserm-00144800⟩

Blandine Pommier, Cynthia Marie-Claire, Sophie da Nascimento, Hung-Li Wang, Bernard Roques, et al.. Further evidence that the CCK2 receptor is coupled to two transduction pathways using site-directed mutagenesis.. Journal of Neurochemistry, Wiley, 2003, 85 (2), pp.454-61. ⟨inserm-00171259⟩

Julie Salzmann, Cynthia Marie-Claire, Stephanie Le Guen, Bernard P Roques, Florence Noble. Importance of ERK activation in behavioral and biochemical effects induced by MDMA in mice.. British Journal of Pharmacology, Wiley, 2003, 140 (5), pp.831-8. ⟨10.1038/sj.bjp.0705506⟩. ⟨inserm-00171261⟩

Cynthia Marie-Claire, Ingrid Laurendeau, Corine Canestrelli, Cindie Courtin, Michel Vidaud, et al.. Fos but not Cart (cocaine and amphetamine regulated transcript) is overexpressed by several drugs of abuse: a comparative study using real-time quantitative polymerase chain reaction in rat brain.. Neuroscience Letters, Elsevier, 2003, 345 (2), pp.77-80. ⟨inserm-00171266⟩

Bing Tang, Satoru Nirasawa, Motomitsu Kitaoka, Cynthia Marie-Claire, Kiyoshi Hayashi. General function of N-terminal propeptide on assisting protein folding and inhibiting catalytic activity based on observations with a chimeric thermolysin-like protease.. Biochemical and Biophysical Research Communications, Elsevier, 2003, 301 (4), pp.1093-8. ⟨inserm-00144798⟩

Cynthia Marie-Claire, Yukihiro Yabuta, Kyoko Suefuji, Hiroshi Matsuzawa, Ujwal Shinde. Folding pathway mediated by an intramolecular chaperone: the structural and functional characterization of the aqualysin I propeptide.. Journal of Molecular Biology, Elsevier, 2001, 305 (1), pp.151-65. ⟨10.1006/jmbi.2000.4233⟩. ⟨inserm-00171014⟩

Cynthia Marie-Claire, Gilles Tiraboschi, Emmanuel Ruffet, Nicolas Inguimbert, Marie-Claude Fournie-Zaluski, et al.. Exploration of the S'1 subsite of neprilysin: a joined molecular modeling and site-directed mutagenesis study.. Proteins - Structure, Function and Bioinformatics, Wiley, 2000, 39 (4), pp.365-71. ⟨inserm-00171018⟩

Cynthia Marie-Claire, Emmanuel Ruffet, Ann Beaumont, Bernard Roques. The prosequence of thermolysin acts as an intramolecular chaperone when expressed in trans with the mature sequence in Escherichia coli.. Journal of Molecular Biology, Elsevier, 1999, 285 (5), pp.1911-5. ⟨10.1006/jmbi.1998.2449⟩. ⟨inserm-00171255⟩

Nathalie Luciani, Cynthia Marie-Claire, Emmanuel Ruffet, Ann Beaumont, Bernard Roques, et al.. Characterization of Glu350 as a critical residue involved in the N-terminal amine binding site of aminopeptidase N (EC 3.4.11.2): insights into its mechanism of action.. Biochemistry, American Chemical Society, 1998, 37 (2), pp.686-92. ⟨10.1021/bi971705p⟩. ⟨inserm-00145193⟩

Cynthia Marie-Claire, Emmanuel Ruffet, Gilles Tiraboschi, Marie-Claude Fournie-Zaluski. Differences in transition state stabilization between thermolysin (EC 3.4.24.27) and neprilysin (EC 3.4.24.11).. FEBS Letters, Wiley, 1998, 438 (3), pp.215-9. ⟨inserm-00145191⟩

Cynthia Marie-Claire, Bernard Roques, Ann Beaumont. Intramolecular processing of prothermolysin.. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 1998, 273 (10), pp.5697-701. ⟨inserm-00145189⟩

Cynthia Marie-Claire, Emmanuel Ruffet, Serge Antonczak, Ann Beaumont, Michael O'Donohue, et al.. Evidence by site-directed mutagenesis that arginine 203 of thermolysin and arginine 717 of neprilysin (neutral endopeptidase) play equivalent critical roles in substrate hydrolysis and inhibitor binding.. Biochemistry, American Chemical Society, 1997, 36 (45), pp.13938-45. ⟨10.1021/bi9712495⟩. ⟨inserm-00171023⟩

D Grillault Laroche, E Curis, F Bellivier, C Nepost, Cindie Courtin, et al.. Childhood maltreatment and HPA axis gene expression in bipolar disorders: A gene network analysis.. Psychoneuroendocrinology, Elsevier, 1970, 120, pp.104753. ⟨10.1016/j.psyneuen.2020.104753⟩. ⟨hal-03024265⟩