CV Accueil - Archive ouverte HAL

	Blockade of the pro‐fibrotic reaction mediated by the miR‐143/‐145 cluster enhances the responses to targeted therapy in melanoma Serena Diazzi , Alberto Baeri , Julien Fassy , Margaux Lecacheur , Oskar Marin‐bejar EMBO Molecular Medicine, 2022, 14 (3), ⟨10.15252/emmm.202115295⟩ Article dans une revue inserm-03574667v1
	Secretion of IL1 by Dedifferentiated Melanoma Cells Inhibits JAK1-STAT3-Driven Actomyosin Contractility of Lymph Node Fibroblastic Reticular Cells Christopher Rovera , Ilona Berestjuk , Margaux Lecacheur , Cassandre Tavernier , Serena Diazzi Cancer Research, 2022, 82 (9), pp.1774-1788. ⟨10.1158/0008-5472.CAN-21-0501⟩ Article dans une revue inserm-03674501v1
	Targeting Discoidin Domain Receptors DDR1 and DDR2 overcomes matrix‐mediated tumor cell adaptation and tolerance to BRAF‐targeted therapy in melanoma Ilona Berestjuk , Margaux Lecacheur , Alexandrine Carminati , Serena Diazzi , Christopher Rovera EMBO Molecular Medicine, 2021, ⟨10.15252/emmm.201911814⟩ Article dans une revue hal-03533365v1
	Inhibition of patched drug efflux increases vemurafenib effectiveness against resistant braf(V600E) melanoma Laurie Signetti , Nelli Elizarov , Méliné Simsir , Agnès Paquet , Dominique Douguet Cancers, 2020, 12 (6), pp.1500. ⟨10.3390/cancers12061500⟩ Article dans une revue hal-02884136v1
	A Feed-Forward Mechanosignaling Loop Confers Resistance to Therapies Targeting the MAPK Pathway in BRAF-Mutant Melanoma Christophe Girard , Margaux Lecacheur , Rania Ben Jouira , Ilona Berestjuk , Serena Diazzi Cancer Research, 2020, 80 (10), pp.1927-1941. ⟨10.1158/0008-5472.CAN-19-2914⟩ Article dans une revue inserm-02889519v1
	Échappement thérapeutique du mélanome : la piste biomécanique Margaux Lecacheur , Christophe A. Girard , Marcel Deckert , Sophie Tartare-Deckert Médecine/Sciences, 2020, 36 (11), pp.961-965. ⟨10.1051/medsci/2020201⟩ Article dans une revue hal-02991398v1
	Cancer cell-derived long pentraxin 3 (PTX3) promotes melanoma migration through a toll-like receptor 4 (TLR4)/NF-κB signaling pathway M. Rathore , Christophe Girard , M. Ohanna , M. Tichet , R. Ben Jouira Oncogene, 2019, 38 (30), pp.5873-5889. ⟨10.1038/s41388-019-0848-9⟩ Article dans une revue hal-02323965v1
	Epitope Spreading of Autoantibody Response to PLA2R Associates with Poor Prognosis in Membranous Nephropathy Barbara Seitz-Polski , Guillaume Dolla , Christine Payré , Christophe Girard , Joel Polidori Journal of the American Society of Nephrology, 2016, 27, pp.1517-33 Article dans une revue hal-01455661v1
	Nouveaux rôles physiopathologiques pour le récepteur PLA2R1 dans le cancer et la glomérulonéphrite extramembraneuse Christophe Girard , Barbara Seitz Seitz-Polski , Guillaume Dolla , Arnaud Augert , David Vindrieux Médecine/Sciences, 2014, 30 (5), pp.519-525. ⟨10.1051/medsci/20143005014⟩ Article dans une revue hal-03016069v1
	Group X Secreted Phospholipase A2 Limits the Development of Atherosclerosis in LDL Receptor–Null Mice Hafid Ait Oufella , Alain Tedgui , Makoto Murakami , Olivier Herbin , Charlotte Lahoute Arteriosclerosis, Thrombosis, and Vascular Biology, 2013, 33 (3), pp.466-473. ⟨10.1161/ATVBAHA.112.300309⟩ Article dans une revue hal-03016106v1
	PLA2R1 kills cancer cells by inducing mitochondrial stress Arnaud Augert , David Vindrieux , Christophe Girard , Benjamin Le Calvé , Baptiste Gras Free Radical Biology and Medicine, 2013, 65, pp.969-977. ⟨10.1016/j.freeradbiomed.2013.08.177⟩ Article dans une revue hal-02395811v1
	PLA2R1 Mediates Tumor Suppression by Activating JAK2 David Vindrieux , Arnaud Augert , Christophe Girard , Delphine Gitenay , Helene Lallet-Daher Cancer Research, 2013, 73 (20), pp.6334-6345. ⟨10.1158/0008-5472.CAN-13-0318⟩ Article dans une revue hal-02395807v1
	Control of Pancreatic β Cell Regeneration by Glucose Metabolism Christophe Girard Cell Metabolism, 2011, 13 (4), pp.440-449. ⟨10.1016/j.cmet.2011.02.012⟩ Article dans une revue hal-03016133v1
	Emerging roles of secreted phospholipase A2 enzymes: Lessons from transgenic and knockout mice. Makoto Murakami , Yoshitaka Taketomi , Christophe Girard , Kei Yamamoto , Gérard Lambeau Biochimie, 2010, 92 (6), pp.561-82. ⟨10.1016/j.biochi.2010.03.015⟩ Article dans une revue hal-00497527v1
	Overexpression of Fto leads to increased food intake and results in obesity Chris Church , Christophe Girard , Lydia Teboul , Jens Brüning , P.M. Nolan Nature Genetics, 2010, 42 (12), pp.1086-1092. ⟨10.1038/ng.713⟩ Article dans une revue hal-03016713v1
	Adjacent mutations in the gating loop of Kir6.2 produce neonatal diabetes and hyperinsulinism Christophe Girard EMBO Molecular Medicine, 2009, 1 (3), pp.166-177. ⟨10.1002/emmm.200900018⟩ Article dans une revue hal-03016139v1
	Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic β cells recapitulates neonatal diabetes Christophe Girard Journal of Clinical Investigation, 2009, ⟨10.1172/JCI35772⟩ Article dans une revue hal-03016127v1
	Mechanism of action of a sulphonylurea receptor SUR1 mutation (F132L) that causes DEND syndrome Christophe Girard Human Molecular Genetics, 2007, 16 (16), pp.2011-2019. ⟨10.1093/hmg/ddm149⟩ Article dans une revue hal-03016446v1
	Permanent Neonatal Diabetes Caused by Dominant, Recessive, or Compound Heterozygous SUR1 Mutations with Opposite Functional Effects Christophe Girard American Journal of Human Genetics, 2007, 81 (2), pp.375-382. ⟨10.1086/519174⟩ Article dans une revue hal-03016441v1
	The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase Thomas Gerken , Christophe Girard , Frances M. Ashcroft Science, 2007, 318 (5855), pp.1469-1472. ⟨10.1126/science.1151710⟩ Article dans une revue hal-03016428v1
	Sulfonylurea improves CNS function in a case of intermediate DEND syndrome caused by a mutation in KCNJ11 Christophe Girard Nature Clinical Practice Neurology, 2007, 3 (11), pp.640-645. ⟨10.1038/ncpneuro0640⟩ Article dans une revue hal-03016431v1
	Functional analysis of six Kir6.2 (KCNJ11) mutations causing neonatal diabetes Christophe Girard , Frances M. Ashcroft Pflügers Archiv European Journal of Physiology, 2006, 453 (3), pp.323-332. ⟨10.1007/s00424-006-0112-3⟩ Article dans une revue hal-03016452v1
	Mutations at the Same Residue (R50) of Kir6.2 (KCNJ11) That Cause Neonatal Diabetes Produce Different Functional Effects Kenju Shimomura , Christophe Girard , Frances M. Ashcroft Diabetes, 2006, 55 (6), pp.1705-1712. ⟨10.2337/db05-1640⟩ Article dans une revue hal-03016473v1
	ATP Sensitivity of the ATP-Sensitive K + Channel in Intact and Permeabilized Pancreatic β-Cells Andrei I. Tarasov , Christophe Girard , Frances M. Ashcroft Diabetes, 2006, 55 (9), pp.2446-2454. ⟨10.2337/db06-0360⟩ Article dans une revue hal-03016460v1
	Functional Effects of Mutations at F35 in the NH2-terminus of Kir6.2 (KCNJ11), Causing Neonatal Diabetes, and Response to Sulfonylurea Therapy Peter Proks , Christophe Girard , Frances M. Ashcroft Diabetes, 2006, 55 (6), pp.1731-1737. ⟨10.2337/db05-1420⟩ Article dans une revue hal-03016732v1

	Blockade of pro-fibrotic response mediated by the miR-143/-145 cluster prevents targeted therapy-induced phenotypic plasticity and resistance in melanoma S. Diazzi , A. Baeri , J. Fassy , M. Lecacheur , O. Marin-Bejar 2021 Pré-publication, Document de travail hal-03417405v1
	Targeting DDR1 and DDR2 overcomes matrix-mediated melanoma cell adaptation to BRAF-targeted therapy Ilona Berestjuk , Margaux Lecacheur , Serena Diazzi , Christopher Rovera , Virginie Prod'Homme 2020 Pré-publication, Document de travail hal-03016761v1

christophe Girard

Présentation

Publications

Blockade of the pro‐fibrotic reaction mediated by the miR‐143/‐145 cluster enhances the responses to targeted therapy in melanoma

Secretion of IL1 by Dedifferentiated Melanoma Cells Inhibits JAK1-STAT3-Driven Actomyosin Contractility of Lymph Node Fibroblastic Reticular Cells

Targeting Discoidin Domain Receptors DDR1 and DDR2 overcomes matrix‐mediated tumor cell adaptation and tolerance to BRAF‐targeted therapy in melanoma

Inhibition of patched drug efflux increases vemurafenib effectiveness against resistant braf(V600E) melanoma

A Feed-Forward Mechanosignaling Loop Confers Resistance to Therapies Targeting the MAPK Pathway in BRAF-Mutant Melanoma

Échappement thérapeutique du mélanome : la piste biomécanique

Cancer cell-derived long pentraxin 3 (PTX3) promotes melanoma migration through a toll-like receptor 4 (TLR4)/NF-κB signaling pathway

Epitope Spreading of Autoantibody Response to PLA2R Associates with Poor Prognosis in Membranous Nephropathy

Nouveaux rôles physiopathologiques pour le récepteur PLA2R1 dans le cancer et la glomérulonéphrite extramembraneuse

Group X Secreted Phospholipase A2 Limits the Development of Atherosclerosis in LDL Receptor–Null Mice

PLA2R1 kills cancer cells by inducing mitochondrial stress

PLA2R1 Mediates Tumor Suppression by Activating JAK2

Control of Pancreatic β Cell Regeneration by Glucose Metabolism

Emerging roles of secreted phospholipase A2 enzymes: Lessons from transgenic and knockout mice.

Overexpression of Fto leads to increased food intake and results in obesity

Adjacent mutations in the gating loop of Kir6.2 produce neonatal diabetes and hyperinsulinism

Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic β cells recapitulates neonatal diabetes

Mechanism of action of a sulphonylurea receptor SUR1 mutation (F132L) that causes DEND syndrome

Permanent Neonatal Diabetes Caused by Dominant, Recessive, or Compound Heterozygous SUR1 Mutations with Opposite Functional Effects

The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase

Sulfonylurea improves CNS function in a case of intermediate DEND syndrome caused by a mutation in KCNJ11

Functional analysis of six Kir6.2 (KCNJ11) mutations causing neonatal diabetes

Mutations at the Same Residue (R50) of Kir6.2 (KCNJ11) That Cause Neonatal Diabetes Produce Different Functional Effects

ATP Sensitivity of the ATP-Sensitive K + Channel in Intact and Permeabilized Pancreatic β-Cells

Functional Effects of Mutations at F35 in the NH2-terminus of Kir6.2 (KCNJ11), Causing Neonatal Diabetes, and Response to Sulfonylurea Therapy

Blockade of pro-fibrotic response mediated by the miR-143/-145 cluster prevents targeted therapy-induced phenotypic plasticity and resistance in melanoma

Targeting DDR1 and DDR2 overcomes matrix-mediated melanoma cell adaptation to BRAF-targeted therapy