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Delivery of cancer therapies by synthetic and bio-inspired nanovectors

Tina Briolay , Tacien Petithomme , Morgane Fouet , Nelly Nguyen-Pham , Christophe Blanquart , et al.
Molecular Cancer, 2021, 20 (1), pp.55. ⟨10.1186/s12943-021-01346-2⟩
Article dans une revue inserm-03187595v1

Nanoparticles Produced by Ring-Opening Metathesis Polymerization Using Norbornenyl-poly(ethylene oxide) as a Ligand-Free Generic Platform for Highly Selective In Vivo Tumor Targeting

Fabien Gueugnon , Iza Denis , Daniel Pouliquen , Floraine Collette , Régis Delatouche , et al.
Biomacromolecules, 2013, 14 (7), pp.2396-2402. ⟨10.1021/bm400516b⟩
Article dans une revue hal-00916100v1
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Brain-derived neurotrophic factor, a new soluble biomarker for malignant pleural mesothelioma involved in angiogenesis

Patrick Smeele , Sènan D’almeida , Clément Meiller , Anne-Laure Chéné , Charly Liddell , et al.
Molecular Cancer, 2018, 17 (1), pp.148. ⟨10.1186/s12943-018-0891-0⟩
Article dans une revue inserm-01904612v1
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Endogenous Retrovirus expression activates type-I interferon signaling in an experimental mouse model of mesothelioma development

Suna Sun , Francesca Frontini , Weihong Qi , Ananya Hariharan , Manuel Ronner , et al.
Cancer Letters, 2021, 507, pp.26 - 38. ⟨10.1016/j.canlet.2021.03.004⟩
Article dans une revue inserm-03171655v1
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Specialized Pro-Resolving Mediators Mitigate Cancer-Related Inflammation: Role of Tumor-Associated Macrophages and Therapeutic Opportunities

Margot Lavy , Vanessa Gauttier , Nicolas Poirier , Sophie C Barillé-Nion , Christophe Blanquart
Frontiers in Immunology, 2021, 12, pp.702785. ⟨10.3389/fimmu.2021.702785⟩
Article dans une revue inserm-03319344v1
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Critical Roles of Tumor Extracellular Vesicles in the Microenvironment of Thoracic Cancers

Lyna Kara-Terki , Lucas Treps , Christophe Blanquart , Delphine Fradin
International Journal of Molecular Sciences, 2020, 21 (17), pp.6024. ⟨10.3390/ijms21176024⟩
Article dans une revue inserm-02946311v1
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A partially demineralized allogeneic bone graft: in vitro osteogenic potential and preclinical evaluation in two different intramembranous bone healing models

Pierre Tournier , Jérôme Guicheux , Arnaud Paré , Aymeric Maltezeanu , Thibaut Blondy , et al.
Scientific Reports, 2021, 11 (1), pp.4907. ⟨10.1038/s41598-021-84039-6⟩
Article dans une revue inserm-03157874v1
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ChemR23 activation reprograms macrophages toward a less inflammatory phenotype and dampens carcinoma progression

Margot Lavy , Vanessa Gauttier , Alison Dumont , Florian Chocteau , Sophie Deshayes , et al.
Frontiers in Immunology, 2023, 14, pp.3606 - 3619. ⟨10.3389/fimmu.2023.1196731⟩
Article dans une revue inserm-04198031v1
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Characterization of increasing stages of invasiveness identifies stromal/cancer cell crosstalk in rat models of mesothelioma

Joëlle Nader , Jérôme Abadie , Sophie Deshayes , Alice Boissard , Stéphanie Blandin , et al.
Oncotarget, 2018, Epub ahead of print
Article dans une revue inserm-01726393v1
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Preclinical evaluation of CDK4 phosphorylation predicts high sensitivity of pleural mesotheliomas to CDK4/6 inhibition

Sabine Paternot , Eric Raspé , C Meiller , Maxime Tarabichi , Jean-Baptiste Assié , et al.
Molecular Oncology, In press, ⟨10.1002/1878-0261.13351⟩
Article dans une revue hal-03898858v1
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PEGylated Anionic Magneto-Fluorescent Nanoassemblies: Impact of their Interface Structure on MRI Contrast and Cellular Uptake

Camille Linot , Julien Poly , Joanna Boucard , Daniel Pouliquen , Steven Nedellec , et al.
ACS Applied Materials & Interfaces, 2017, 9 (16), pp.14242-14257. ⟨10.1021/acsami.7b01737⟩
Article dans une revue inserm-01522631v1
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Histone Deacetylase Inhibitors Delivery using Nanoparticles with Intrinsic Passive Tumor Targeting Properties for Tumor Therapy

Fatima El Bahhaj , Iza Denis , Pichavant Loic , Régis Delatouche , Floraine Collette , et al.
Theranostics, 2016, 6 (6), pp.795-807. ⟨10.7150/thno.13725⟩
Article dans une revue inserm-01299450v1
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Triggering the resolution of inflammation with agonistic anti-ChemR23 antibody dampens inflammation-driven carcinogenesis and metastasis

Vanessa Gauttier , Margot Lavy , Charlène Trilleaud , Kévin Biteau , Stéphanie Neyton , et al.
American Association for Cancer Researc 2021, 2021, Virtual Meeting, United States
Poster de conférence inserm-03349406v1

Impact of chemotherapy on lung cancer cells and their microenvironment, evaluated in tridimensional multicellular tumor spheroids

Pauline Hulo , Sophie Deshayes , Virginie Dehame , Marc Grégoire , Jaafar Bennouna , et al.
AACR Annual Meeting 2020, Apr 2020, Philadelphia, United States. pp.319-319, ⟨10.1158/1538-7445.AM2020-319⟩
Communication dans un congrès inserm-03498348v1
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Human MuStem cells repress T-cell proliferation and cytotoxicity through both paracrine and contact-dependent pathways

Marine Charrier , Judith Lorant , Rafael Contreras-Lopez , Gautier Téjédor , Christophe Blanquart , et al.
Current Stem Cell Research & Therapy, 2022, 13 (1), pp.7. ⟨10.1186/s13287-021-02681-3⟩
Article dans une revue inserm-03561720v1
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Frequent Homozygous Deletions of Type I Interferon Genes in Pleural Mesothelioma Confer Sensitivity to Oncolytic Measles Virus

Tiphaine Delaunay , Carole Achard , Nicolas Boisgerault , Marion Grard , Tacien Petithomme , et al.
Journal of Thoracic Oncology, 2020, S1556-0864(20)30019-8, Epub ahead of print. ⟨10.1016/j.jtho.2019.12.128⟩
Article dans une revue inserm-02447160v1
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Peroxisome Proliferator-activated Receptor α (PPARα) Turnover by the Ubiquitin-Proteasome System Controls the Ligand-induced Expression Level of Its Target Genes

Christophe Blanquart , Olivier Barbier , Jean-Charles Fruchart , Bart Staels , Corine Glineur
Journal of Biological Chemistry, 2002, 277 (40), pp.37254. ⟨10.1074/jbc.M110598200⟩
Article dans une revue inserm-02474752v1
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Characterization of preneoplastic and neoplastic rat mesothelial cell lines: the involvement of TETs, DNMTs, and 5-hydroxymethylcytosine

David Roulois , Sophie Deshayes , Marie-Noëlle Guilly , Joëlle Nader , Charly Liddell , et al.
Oncotarget, 2016
Article dans une revue inserm-01306838v1
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Pleiotropic Actions of Peroxisome Proliferator-Activated Receptors in Lipid Metabolism and Atherosclerosis

O. Barbier , I Pineda Torra , Y Duguay , Christophe Blanquart , J.-C Fruchart , et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2002, 22 (5), pp.717-26. ⟨10.1161/01.atv.0000015598.86369.04⟩
Article dans une revue inserm-02912615v1
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Cross metathesis with hydroxamate and benzamide BOC-protected alkenes to access HDAC inhibitors and their biological evaluation highlighted intrinsic activity of BOC-protected dihydroxamates

Vincent Zwick , Alessandra Nurisso , Claudia Simões-Pires , Samuel Bouchet , Nadine Martinet , et al.
Bioorganic and Medicinal Chemistry Letters, 2016, ⟨10.1016/j.bmcl.2015.11.011⟩
Article dans une revue inserm-01299475v1
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Demonstration of immunomodulatory properties for the human MuStem cell population, a promising candidate for cell therapy of muscular dystrophies

Marine Charrier , Judith Lorant , Rafael Contreras Lopez , Christophe Blanquart , Blandine Lieubeau-Teillet , et al.
2nd annual meeting of French Society for Stem Cell Research, Dec 2018, Nantes, France. 2018
Poster de conférence hal-01959646v1
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KRAS signaling in malignant pleural mesothelioma

Antonia Marazioti , Anthi C Krontira , Sabine J Behrend , Georgia A Giotopoulou , Giannoula Ntaliarda , et al.
EMBO Molecular Medicine, 2021, pp.e13631. ⟨10.15252/emmm.202013631⟩
Article dans une revue inserm-03483560v1

Histone deacetylase inhibitor-polymer conjugate nanoparticles for acid-responsive drug delivery

Iza Denis , Fatima El Bahhaj , Floraine Collette , Régis Delatouche , Fabien Gueugnon , et al.
European Journal of Medicinal Chemistry, 2015, 95, pp.369-376. ⟨10.1016/j.ejmech.2015.03.037⟩
Article dans une revue hal-01368838v1

Easy and effective method to produce functionalized particles for cellular uptake

Floraine Collette , Régis Delatouche , Christophe Blanquart , Fabien Gueugnon , Marc Gregoire , et al.
Journal of Polymer Science Part A: Polymer Chemistry, 2012, 51 (1), pp.176-189. ⟨10.1002/pola.26357⟩
Article dans une revue istex hal-00758913v1
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The DCMU Herbicide Shapes T-cell Functions By Modulating Micro-RNA Expression Profiles

Pierre Autin , Sophie Deshayes , Juliette Lea , Nicolas Boisgerault , Emilie Dupré , et al.
Frontiers in Immunology, 2022, 13, pp.925241. ⟨10.3389/fimmu.2022.925241⟩
Article dans une revue inserm-03752032v1
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Prise en compte de l'adaptation des propriétés mécaniques de la cellule pendant l'endocytose de nanoparticules

Sarah Iaquinta , Shahram Khazaie , Sylvain Fréour , Frédéric Jacquemin , Christophe Blanquart , et al.
15e journées du Cancéropôle Nantes Angers, Jul 2021, Angers, France
Poster de conférence hal-03993849v1
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New Insights into the Epigenetic Activities of Natural Compounds

Melita Vidakovic , Jessica Marinello , Maija Lahtela-Kakkonen , Daumantas Matulis , Vaida Linkuvienė , et al.
OBM Genetics, 2018, 131 (8), pp.3033-41. ⟨10.21926/obm.genet.1803029⟩
Article dans une revue inserm-01981397v1
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Extending Cross Metathesis To Identify Selective HDAC Inhibitors: Synthesis, Biological Activities, and Modeling

Samuel Bouchet , Camille Linot , Dusan Ruzic , Danica Agbaba , Benoit Fouchaq , et al.
ACS Medicinal Chemistry Letters, 2019, 10 (6), pp.863-868. ⟨10.1021/acsmedchemlett.8b00440⟩
Article dans une revue inserm-02265954v1
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Small Molecule-Based Fluorescent Organic Nanoassemblies with Strong Hydrogen Bonding Networks for Fine Tuning and Monitoring Drug Delivery in Cancer Cells

Joanna Boucard , Camille Linot , Thibaut Blondy , Steven Nedellec , Philippe Hulin , et al.
Small, 2018, 14 (38), pp.e1802307. ⟨10.1002/smll.201802307⟩
Article dans une revue inserm-01885511v1
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Involvement of the M-CSF/IL-34/CSF- 1R pathway in malignant pleural mesothelioma

Thibaut Blondy , Sènan Mickael d'Almeida , Tina Briolay , Julie Tabiasco , Clément Meiller , et al.
Journal for Immunotherapy of Cancer, 2020, 8 (1), pp.e000182. ⟨10.1136/jitc-2019-000182⟩
Article dans une revue inserm-02913733v1