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Christoph Grunau

The goal of our group is to elucidate the multiple relations between environment, organisms and their fitness in the lab and in the field, in order to understand and control host-symbiont/parasite interactions. We see inheritance in a broad sense including genetic, epigenetic, cytoplasmic, and holobiont elements.
My specialty is evolutionary epigenetics.

Sep 2011 – Sep 2011

Université de Perpignan

HDR, Epigenetics

Perpignan, France

Jan 1995 – Dec 1999

IMB Jena

PhD, Epigenetics

Jena, Thuringia, Germany

Sep 1994 – Dec 1995


PreDoc, Microbiology

Wako, Japan

Sep 1988 – Aug 1994

Friedrich-Schiller-University Jena

Diploma, Biology

Jena, Germany

Research Experience

Sep 2013 – present

Professor (Full)

Université de Perpignan, Laboratory of Host-Pathogen-Environnement Interactions (IHPE)

Perpignan, France

Sep 2007 – Aug 2013

Professor (Assistant)

Université de Perpignan, Laboratory of Ecology and Evolution of Interactions 2EI

Perpignan, France

Sep 2006 – Aug 2007

PostDoc Position

Université de Perpignan, 

Perpignan, France

Jan 2000 – Mar 2005

PostDoc Position

French National Centre for Scientific Research, Institut de Génétique Humaine

Montpellier, Languedoc-Roussillon, France

Jan 2000 – Feb 2005

PostDoc Position

Institut de Génétique Humaine, 

Montpellier, France

Jan 1996 – Dec 1999

PhD Student

Institute of Molecular Biotechnology, Jena, 

Jena, Thuringia, Germany

Oct 1994 – Dec 1995


RIKEN, Intestinal Microbe Symbiosis Research Laboratory

Wako, Saitama, Japan

Sep 1993 – Aug 1994


Max-Delbrück-Centrum für Molekulare Medizin, 

Berlin, Germany

Journal articles60 documents

  • Marion Picard, Beatriz Vicoso, David Roquis, Ingo Bulla, Ronaldo de Carvalho Augusto, et al.. Dosage compensation throughout the Schistosoma mansoni lifecycle: specific chromatin landscape of the Z chromosome. Genome Biology and Evolution, Society for Molecular Biology and Evolution, 2019, 11 (7), pp.1909-1922. ⟨10.1093/gbe/evz133/5527757⟩. ⟨hal-02177468⟩
  • Ronaldo de Carvalho Augusto, David Duval, Christoph Grunau. Effects of the environment on developmental plasticity and infection success of Schistosoma parasites – an epigenetic perspective. Frontiers in Microbiology, Frontiers Media, 2019, 10, pp.1475. ⟨10.3389/fmicb.2019.01475⟩. ⟨hal-02178309⟩
  • Benoît Aliaga, Ingo Bulla, Gabriel Mouahid, David Duval, Christoph Grunau. Universality of the DNA methylation codes in Eucaryotes. Scientific Reports, Nature Publishing Group, 2019, 9, pp.173. ⟨hal-01905101⟩
  • Christoph Grunau, Jérémy Le Luyer, Martin Laporte, Dominique Joly. The Epigenetics Dilemma. Genes, MDPI, 2019, 11 (1), pp.23. ⟨10.3390/genes11010023⟩. ⟨hal-02428660⟩
  • Gabriel Mouahid, Anne Rognon, Ronaldo de Carvalho Augusto, Patrick Driguez, Kathy Geyer, et al.. Transplantation of schistosome sporocysts between host snails: A video guide. Wellcome Open Research, F1000Research, 2018, 3, pp.3. ⟨10.12688/wellcomeopenres.13488.1⟩. ⟨hal-01729358⟩
  • Julien Kincaid-Smith, Marion A.-L. Picard, Celine Cosseau, Jerome Boissier, Dany Severac, et al.. Parent-of-Origin Dependent Gene Expression in Male and Female Schistosome Parasites. Genome Biology and Evolution, Society for Molecular Biology and Evolution, In press, 10 (3), pp.840-856. ⟨10.1093/gbe/evy037⟩. ⟨hal-01729365⟩
  • Ingo Bulla, Benoît Aliaga, Virginia Lacal, Jan Bulla, Christoph Grunau, et al.. Notos -a galaxy tool to analyze CpN observed expected ratios for inferring DNA methylation types. BMC Bioinformatics, BioMed Central, 2018, 19, pp.105. ⟨10.1186/s12859-018-2115-4⟩. ⟨hal-01746203⟩
  • David Roquis, Aaron Taudt, Kathrin Geyer, Gilda Padalino, Karl Hoffmann, et al.. Histone methylation changes are required for life cycle progression in the human parasite Schistosoma mansoni. PLoS Pathogens, Public Library of Science, 2018, 14 (5), pp.e1007066. ⟨10.1371/journal.ppat.1007066⟩. ⟨hal-01808531⟩
  • Christoph Grunau, Susanne Voigt, Ralph Dobler, Damian Dowling, Klaus Reinhardt. The Cytoplasm Affects the Epigenome in Drosophila melanogaster. Epigenomes, MDPI, 2018, 2 (3), pp.17. ⟨10.3390/epigenomes2030017⟩. ⟨hal-01887456⟩
  • Arnaud Sentis, Raphaël Bertram, Nathalie Dardenne, Felipe Ramon-Portugal, Gilles Espinasse, et al.. Evolution without standing genetic variation: change in transgenerational plastic response under persistent predation pressure. Heredity, Nature Publishing Group, 2018, 121 (3), pp.266-281. ⟨10.1038/s41437-018-0108-8⟩. ⟨hal-01887396⟩
  • Richard Galinier, Emmanuel Roger, Yves Moné, David Duval, Anaïs Portet, et al.. A multistrain approach to studying the mechanisms underlying compatibility in the interaction between Biomphalaria glabrata and Schistosoma mansoni. PLoS Neglected Tropical Diseases, Public Library of Science, 2017, 11 (3), pp.e0005398. ⟨10.1371/journal.pntd.0005398.s005⟩. ⟨hal-01511153⟩
  • Kathrin Geyer, Umar Niazi, David Duval, Céline Cosseau, Chad Tomlinson, et al.. The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions with Schistosoma mansoni. PLoS Neglected Tropical Diseases, Public Library of Science, 2017, 11 (5), pp.e0005246. ⟨10.1371/journal.pntd.0005246⟩. ⟨hal-01523805⟩
  • Ronaldo de Carvalho Augusto, Guillaume Tetreau, Philippe Chan, Marie-Laure Walet-Balieu, Clélia Christina Mello-Silva, et al.. Double impact: natural molluscicide for schistosomiasis vector control also impedes development of Schistosoma mansoni cercariae into adult parasites. PLoS Neglected Tropical Diseases, Public Library of Science, 2017, 11 (7), pp.e0005789. ⟨10.1371/journal.pntd.0005789⟩. ⟨hal-01598383⟩
  • Rodolfo Rondon, Christoph Grunau, Manon Fallet, Nicolas Charlemagne, Rossana Sussarellu, et al.. Effects of a parental exposure to diuron on Pacific oyster spat methylome. Environmental Epigenetics, Oxford University Press, 2017, 3 (1), pp.dvx004. ⟨10.1093/eep/dvx004⟩. ⟨hal-01511486⟩
  • Guillaume Mitta, Benjamin Gourbal, Christoph Grunau, M. Knight, J.M. Bridger, et al.. The compatibility between Biomphalaria glabrata snails and Schistosoma mansoni: an increasingly complex puzzle. Advances in Parasitology, Elsevier, 2017, 97, pp.111-145. ⟨10.1016/bs.apar.2016.08.006⟩. ⟨hal-01511043⟩
  • Céline Cosseau, Olaf Wolkenhauer, Gilda Padalino, Kathrin K. Geyer, Karl F. Hoffmann, et al.. (Epi)genetic inheritance in Schistosoma mansoni: a system approach. Trends in Parasitology, Elsevier, 2017, 1590, pp.285-294. ⟨10.1016/⟩. ⟨hal-01511049⟩
  • Anaïs Portet, Silvain Pinaud, Guillaume Tetreau, Richard Galinier, Céline Cosseau, et al.. Integrated multi-omic analyses in Biomphalaria-Schistosoma dialogue reveal the immunobiological significance of FREP- Sm PoMuc interaction. Developmental and Comparative Immunology, Elsevier, 2017, 75, pp.16 - 27. ⟨10.1016/j.dci.2017.02.025⟩. ⟨hal-01598455⟩
  • C. Adema, L. Hillier, C. Jones, E.S. Loker, M. Knight, et al.. Whole genome analysis of a schistosomiasis-transmitting freshwater snail. Nature Communications, Nature Publishing Group, 2017, 8, pp.15451. ⟨10.1038/ncomms15451⟩. ⟨hal-01523953⟩
  • Marion Picard, Jérôme Boissier, David Roquis, Christoph Grunau, Jean-François Allienne, et al.. Sex-biased transcriptome of Schistosoma mansoni: host-parasite interaction, genetic determinants and epigenetic regulators are associated with sexual differentiation. PLoS Neglected Tropical Diseases, Public Library of Science, 2016, 10 (9), pp.e0004930. ⟨10.1371/journal.pntd.0004930.s010⟩. ⟨hal-01387886⟩
  • Sara Fneich, André Théron, Céline Cosseau, Anne Rognon, Benoit Aliaga, et al.. Epigenetic origin of adaptive phenotypic variants in the human blood-fluke Schistosoma mansoni. Epigenetics and Chromatin, BioMed Central, 2016, 9, pp.227. ⟨10.1186/s13072-016-0076-2⟩. ⟨hal-01364014⟩
  • David Roquis, Anne Rognon, Cristian Chapparo, Jérôme Boissier, Nathalie Arancibia, et al.. Frequency and mitotic heritability of epimutations in Schistosoma mansoni. Molecular Ecology, Wiley, 2016, EPIGENETIC STUDIES IN ECOLOGY AND EVOLUTION, 25 (8), pp.1741-1758. ⟨10.1111/mec.13555⟩. ⟨hal-01311089⟩
  • Rodolfo Rondon, F. Akcha, P. Alonso, D. Menard, J. Rouxel, et al.. Transcriptional changes in Crassostrea gigas oyster spat following a parental exposure to the herbicide diuron. Aquatic Toxicology, Elsevier, 2016, 175, pp.47-55. ⟨10.1016/j.aquatox.2016.03.007⟩. ⟨hal-01311107⟩
  • David Roquis, Julie Mireille Lepesant, Marion A.L. Picard, M. Freitag, Hugues Parrinello, et al.. The Epigenome of Schistosoma mansoni Provides Insight about How Cercariae Poise Transcription until Infection. PLoS Neglected Tropical Diseases, Public Library of Science, 2015, 9 (8), pp.e0003853. ⟨10.1371/journal.pntd.0003853⟩. ⟨hal-01259820⟩
  • Marion A.L. Picard, Céline Cosseau, Gabriel Mouahid, David Duval, Christoph Grunau, et al.. The roles of DMRT (Double sex/Male-abnormal-3 Related Transcription factor) genes in sex determination and differentiation mechanisms: ubiquity and diversity across the animal kingdom. Comptes Rendus Biologies, Elsevier Masson, 2015, 338 (7), pp.451-462. ⟨10.1016/j.crvi.2015.04.010⟩. ⟨hal-01163079⟩
  • Nolwenn M Dheilly, David Duval, Gabriel Mouahid, Rémi Emans, Jean-François Allienne, et al.. A family of variable immunoglobulin and lectin domain containing molecules in the snail Biomphalaria glabrata. Developmental and Comparative Immunology, Elsevier, 2015, 48 (1), pp.234-243. ⟨10.1016/j.dci.2014.10.009⟩. ⟨hal-01082870⟩
  • N.D. Tossavi, A Gbankoto, A Adité, Moudachirou Ibikounlé, Christoph Grunau, et al.. Metazoan parasite communities of catfishes (Teleostei: Siluridae) in Benin (West Africa).. Parasitology Research, Springer Verlag (Germany), 2014, 113 (11), pp.3973-3983. ⟨10.1007/s00436-014-4063-x⟩. ⟨hal-01112591⟩
  • David Roquis, Julie M. J. Lepesant, Emanuel Villafan, Jérôme Boissier, Cristina Vieira, et al.. Exposure to hycanthone alters chromatin structure around specific gene functions and specific repeats in Schistosoma mansoni.. Frontiers in Genetics, Frontiers, 2014, 5, pp.207. ⟨10.3389/fgene.2014.00207⟩. ⟨hal-01112701⟩
  • Jeremie Vidal-Dupiol, Nolwenn M Dheilly, Rodolfo Rondon, Christoph Grunau, Cé Line Cosseau, et al.. Thermal Stress Triggers Broad Pocillopora damicornis Transcriptomic Remodeling, while Vibrio coralliilyticus Infection Induces a More Targeted Immuno-Suppression Response. PLoS ONE, Public Library of Science, 2014, 9 (9), pp.e107672. ⟨10.1371/journal.pone⟩. ⟨hal-01112610⟩
  • Nolwenn M Dheilly, Coen Adema, David A Raftos, Benjamin Gourbal, Christoph Grunau, et al.. No more non-model species: The promise of next generation sequencing for comparative immunology.. Developmental and Comparative Immunology, Elsevier, 2014, 45 (1), pp.56-66. ⟨10.1016/j.dci.2014.01.022⟩. ⟨halsde-00965375⟩
  • Laetitia Perfus-Barbeoch, Philippe Castagnone-Sereno, Michael Reichelt, Sara Fneich, David Roquis, et al.. Elucidating the molecular bases of epigenetic inheritance in non-model invertebrates: the case of the root-knot nematode Meloidogyne incognita. Frontiers in Physiology, Frontiers, 2014, 5, pp.211. ⟨10.3389/fphys.2014.00211⟩. ⟨hal-01112344⟩
  • Sara Fneich, Nolwenn Dheilly, Coen Adema, Anne Rognon, Michael Reichelt, et al.. 5-methyl-cytosine and 5-hydroxy-methyl-cytosine in the genome of Biomphalaria glabrata, a snail intermediate host of Schistosoma mansoni.. Parasites and Vectors, BioMed Central, 2013, 6, pp.167. ⟨10.1186/1756-3305-6-167⟩. ⟨halsde-00839033⟩
  • Frédéric Thomas, Daniel Fisher, Philippe Fort, Jean-Pierre Marie, Simon Daoust, et al.. Applying ecological and evolutionary theory to cancer: a long and winding road. Evolutionary Applications, Blackwell, 2013, 6 (1), pp.1-10. ⟨10.1111/eva.12021⟩. ⟨halsde-00790602⟩
  • Jérémie Vidal-Dupiol, Didier Zoccola, Eric Tambutté, Christoph Grunau, Céline Cosseau, et al.. Genes related to ion-transport and energy production are upregulated in response to CO2-Driven pH decrease in corals: new insights from transcriptome analysis. PLoS ONE, Public Library of Science, 2013, 8 (3), pp.e58652. ⟨halsde-00805879⟩
  • Cecile Perrin, Julie Mireille Lepesant, Emmanuel Roger, David Duval, Sara Fneich, et al.. Schistosoma mansoni mucin genes expression (SmPoMuc): an epigenetic control to shape the adaptation to new host. PLoS Pathogens, Public Library of Science, 2013, 9 (8), pp.e1003571. ⟨10.1371/journal.ppat.1003571⟩. ⟨halsde-00856613⟩
  • Julie M J Lepesant, Jérôme Boissier, Déborah Climent, Céline Cosseau, Christoph Grunau. Female biased sex-ratio in Schistosoma mansoni after exposure to an allopatric intermediate host strain of Biomphalaria glabrata.. Experimental Parasitology, Elsevier, 2013, 135, pp.350-356. ⟨10.1016/j.exppara.2013.07.023⟩. ⟨halsde-00856611⟩
  • Julie a J Clément, Eve Toulza, Mathieu Gautier, Hugues Parrinello, David Roquis, et al.. Private Selective Sweeps Identified from Next-Generation Pool-Sequencing Reveal Convergent Pathways under Selection in Two Inbred Schistosoma mansoni Strains.. PLoS Neglected Tropical Diseases, Public Library of Science, 2013, 7 (12), pp.e2591. ⟨10.1371/journal.pntd.0002591⟩. ⟨hal-00938922⟩
  • Julie Mj Lepesant, Celine Cosseau, Jerome Boissier, Michael Freitag, Julien Portela, et al.. Chromatin structure changes around satellite repeats on the Schistosoma mansoni female sex chromosome suggest a possible mechanism for sex chromosome emergence.. Genome Biology, BioMed Central, 2012, 13 (2), pp.R14. ⟨10.1186/gb-2012-13-2-r14⟩. ⟨halsde-00677346⟩
  • Julie Mireille Lepesant, David Roquis, Rémi Emans, Céline Cosseau, Nathalie Arancibia, et al.. Combination of de-novo assembly of massive sequencing reads with classical repeat prediction improves identification of repetitive sequences in Schistosoma mansoni. Experimental Parasitology, Elsevier, 2012, 130 (4), pp.470-474. ⟨10.1016/j.exppara.2012.02.010⟩. ⟨halsde-00674586⟩
  • J. M. J. Lepesant, C. Grunau, C. Cosseau. Towards an understanding of the epigenetics of schistosomes: a comparative epigenomic study. Memorias do Instituto Oswaldo Cruz, 2011, 106 (7), pp.823-830. ⟨halsde-00643863⟩
  • Céline Cosseau, Christoph Grunau. Native chromatin immunoprecipitation.. Methods in Molecular Biology, Humana Press/Springer Imprint, 2011, 791, pp.195-212. ⟨10.1007/978-1-61779-316-5_15⟩. ⟨halsde-00629480⟩
  • S. Beltran, B. Gourbal, J. Boissier, D. Duval, S. Kieffer-Jaquinod, et al.. Vertebrate host protective immunity drives genetic diversity and antigenic polymorphism in Schistosoma mansoni.. Journal of Evolutionary Biology, Wiley, 2011, 24 (3), pp.554-72. ⟨10.1111/j.1420-9101.2010.02190.x⟩. ⟨halsde-00580773⟩
  • M. M. Mourão, C. Grunau, P. T. Loverde, M. K. Jones, G. Oliveira. Recent advances in Schistosoma genomics.. Parasite Immunology, Wiley, 2011, 34 (2-3), pp.151-162. ⟨10.1111/j.1365-3024.2011.01349.x⟩. ⟨halsde-00665474⟩
  • Julien Portela, Christoph Grunau, Celine Cosseau, Sophie Beltran, Christelle Dantec, et al.. Whole-genome in-silico subtractive hybridization (WISH) - using massive sequencing for the identification of unique and repetitive sex-specific sequences: the example of Schistosoma mansoni.. BMC Genomics, BioMed Central, 2010, 11 (1), pp.387. ⟨10.1186/1471-2164-11-387⟩. ⟨halsde-00495369⟩
  • Christoph Grunau, Jérôme Boissier. No evidence for lateral gene transfer between salmonids and schistosomes.. Nature Genetics, Nature Publishing Group, 2010, 42 (11), pp.918-9. ⟨10.1038/ng1110-918⟩. ⟨halsde-00608638⟩
  • Sylvain Chantepie, Dominique Vaur, Christoph Grunau, Véronique Salaün, Mélanie Briand, et al.. ZAP-70 intron1 DNA methylation status: Determination by pyrosequencing in B chronic lymphocytic leukemia. Leukemia Research, Elsevier, 2010, 34 (6), pp.800-808. ⟨10.1016/j.leukres.2009.10.018⟩. ⟨hal-02358614⟩
  • S.P. Chantepie, S. Vaur, Christoph Grunau, V. Salaün, M. Briand, et al.. ZAP-70 intron 1 DNA methylation status: Determination by pyrosequencing in B chronic lymphocytic leukemia. Leukemia Research, Elsevier, 2010, 34 (6), pp.800-808. ⟨10.1016/j.leukres.2009.10.018⟩. ⟨halsde-00495188⟩
  • M.S. Blouin, V. Thuillier, B. Cooper, V. Amarasinghe, L. Cluzel, et al.. No evidence for large difference in genomic methylation between wild and hatchery steelhead (Oncorhynchus mykiss). Canadian Journal of Fisheries and Aquatic Sciences, NRC Research Press, 2010, 67 (2), pp.217-224. ⟨10.1139/F09-174⟩. ⟨halsde-00495179⟩
  • Céline Cosseau, A. Azzi, A. Rognon, J. Boissier, S. Gourbière, et al.. Epigenetic and phenotypic variability in populaitons of Schistosoma mansoni - a possible kick-off for adaptative host/parasite evolution. Oikos, Nordic Ecological Society, 2010, 119 (4), pp.669-678. ⟨10.1111/j.1600-0706.2009.18040.x⟩. ⟨halsde-00495189⟩
  • A. Azzi, C. Cosseau, C. Grunau. Schistosoma mansoni: Developmental arrest of miracidia treated with histone deacetylase inhibitors. Experimental Parasitology, Elsevier, 2009, 121, pp.288-291. ⟨10.1016/j.exppara.2008.11.010⟩. ⟨halsde-00371695⟩
  • Céline Cosseau, Abdelhalim Azzi, Kristina Smith, Michael Freitag, Guillaume Mitta, et al.. Native chromatin immunoprecipitation (N-ChIP) and ChIP-Seq of Schistosoma mansoni: Critical experimental parameters.. Molecular and Biochemical Parasitology, Elsevier, 2009, 166 (1), pp.70-6. ⟨10.1016/j.molbiopara.2009.02.015⟩. ⟨halsde-00459175⟩
  • Florence Dubois, Stéphanie Caby, Frédérik Oger, Céline Cosseau, Monique Capron, et al.. Histone deacetylase inhibitors induce apoptosis, histone hyperacetylation and up-regulation of gene transcription in Schistosoma mansoni.. Molecular and Biochemical Parasitology, Elsevier, 2009, 168 (1), pp.7-15. ⟨10.1016/j.molbiopara.2009.06.001⟩. ⟨halsde-00459184⟩
  • C. Grunau, Me Brun, I. Rivals, J. Selves, W. Hindermann, et al.. BAGE hypomethylation, a new epigenetic biomarker for colon cancer detection. Cancer Epidemiology, Biomarkers and Prevention, American Association for Cancer Research, 2008, 17 (6), pp.1374-1379. ⟨10.1158/1055-9965.EPI-07-2656⟩. ⟨hal-00289933⟩
  • E. Roger, G. Mitta, Y. Moné, A. Bouchut, A. Rognon, et al.. Molecular determinants of compatibility polymorphism in the Biomphalaria glabrata / Schistosoma mansoni model: New candidates identified by a global comparative proteomics approach. Molecular and Biochemical Parasitology, Elsevier, 2008, 157, pp.205-216. ⟨10.1016/j.molbiopara.2007.11.003⟩. ⟨halsde-00286494⟩
  • E. Roger, B. Gourbal, C. Grunau, R.J. Pierce, R. Galinier, et al.. Expression analysis of highly polymorphic mucin proteins (Sm PoMuc) from the parasite Schistosoma mansoni. Molecular and Biochemical Parasitology, Elsevier, 2008, 157, pp.217-227. ⟨10.1016/j.molbiopara.2007.11.015⟩. ⟨halsde-00286479⟩
  • A. Bouchut, Elise Roger, B. Gourbal, Christoph Grunau, Christine Cousteau, et al.. The compatibility polymorphism in invertebrate host/trematode interactions : research of molecular determinants. Parasite, EDP Sciences, 2008, 15, pp.304-309. ⟨10.1051/parasite/2008153304⟩. ⟨hal-02668649⟩
  • A. Bouchut, E. Roger, B. Gourbal, C. Grunau, C. Coustau, et al.. The compatibility polymorphism in invertebrate host/trematodes interactions: research of molecular determinants. Parasite, EDP Sciences, 2008, 15 (3), pp.304-309. ⟨halsde-00344425⟩
  • Emmanuel Roger, Christoph Grunau, Raymond Pierce, Hirohisa Hirai, Benjamin Gourbal, et al.. Controlled chaos of polymorphic mucins in a metazoan parasite (Schistosoma mansoni) interacting with its invertebrate host (Biomphalaria glabrata).. PLoS Neglected Tropical Diseases, Public Library of Science, 2008, 2 (11), pp.e330. ⟨10.1371/journal.pntd.0000330⟩. ⟨halsde-00344615⟩
  • François Guillou, Emmanuel Roger, Yves Moné, Anne Rognon, Christoph Grunau, et al.. Excretory-secretory proteome of larval Schistosoma mansoni and Echinostoma caproni, two parasites of Biomphalaria glabrata.. Molecular and Biochemical Parasitology, Elsevier, 2007, 155 (1), pp.45-56. ⟨10.1016/j.molbiopara.2007.05.009⟩. ⟨hal-00170690⟩
  • C. Grunau, J. Buard, Me Brun, A. de Sario. Mapping of the juxtacentromeric heterochromatin-euchromatin frontier of human chromosome 21.. Genome Research, Cold Spring Harbor Laboratory Press, 2006, 16, pp.1198-1207. ⟨10.1101/gr.5440306⟩. ⟨hal-00113088⟩
  • Krieger S, Grunau C, Sabbah M, Brigitte Sola. Cyclin D1 Gene Activation in Human Myeloma Cells Is Independent of DNA Hypomethylation or Histone Hyperacetylation.. Experimental Hematology, Elsevier, 2005, ⟨10.1016/j.exphem.2005.03.011⟩. ⟨hal-01762030⟩

Conference papers7 documents

  • Sara Fneich, Céline Cosseau, André Théron, Anne Rognon, Guillaume Mitta, et al.. L’héritabilité des mécanismes épigénétiques contrôlant le succès d’infestation du parasite Schistosoma mansoni. 9e Réunion du REID Réseau Ecologie des Interactions Durables, Feb 2014, Montpellier, France. ⟨hal-01134509⟩
  • David Roquis, Céline Cosseau, Christoph Grunau. Evolution adaptative : et si Lamarck avait raison ?. 3e congrès pluridisciplinaire des Doctorants UPVD, Université de Perpignan Via Domitia, May 2014, Perpignan, France. ⟨hal-01164367⟩
  • J. Lepesant, C. Cosseau, C. Perrin, G. Mitta, C. Grunau. A role for epigenetics in adaptative evolution. Young Researchers in Life Sciences, Jun 2010, Paris, France. ⟨halsde-00495195⟩
  • E. Roger, B.E.F. Gourbal, C. Grunau, R. Pierce, G. Mitta. Des mucines polymorphes (SmPoMucs) au coeur de l'interaction entre B. glabrata et S. mansoni. Réunion annuelle du Réseau Ecologie des Interactions Durables, Jan 2008, Tours, France. ⟨halsde-00329976⟩
  • Y. Moné, E. Roger, C. Grunau, B. Gourbal, G. Mitta. Déterminants moléculaires de la compatibilité dans l'interaction Biomphalaria glabrata / Schistosoma mansoni : approche protéomique comparative et caractérisation des mucines polymorphes de S. mansoni (SmPoMuc). Immuninv 2008, Apr 2008, Montpellier, France. ⟨halsde-00330460⟩
  • E. Roger, C. Grunau, H. Hirai, R. Pierce, B. Gourbal, et al.. Le polymorphisme de mucines (SmPoMucs) au coeur de l'interaction entre B. glabrata et S. mansoni : un "chaos contrôlé". Immuninv. 2008, Apr 2008, Montpellier, France. ⟨halsde-00329916⟩
  • E. Roger, C. Grunau, B.E.F. Gourbal, C. Cosseau, G. Mitta. The compatibility polymorphism in trematodes/invertebrate host interactions: research of molecular determinants. Xth EMOP European Multicolloquium Of Parasitology, Aug 2008, Paris, France. ⟨halsde-00329971⟩

Poster communications2 documents

  • Manon Fallet, Bruno Petton, Julien de Lorgeril, Sébastien Comarmond, Cristian Chaparro, et al.. Transgenerational response to early microbial exposure in the oyster Crassostrea gigas and positive impact on survival capacities to juvenile mortality syndrome. 5. Journée d'Animation Scientifique du réseau épiPhase, Jun 2019, Toulouse, France. 35 p., 2019, épiPHASE. ⟨hal-02736036⟩
  • Céline Cosseau, Julie M J Lepesant, David Roquis, Nathalie Arancibia, Christoph Grunau. Environmentally induced epigenetic plasticity in the human parasite Schistosoma mansoni. Conférences Jacques Monod « Les maladies infectieuses comme moteur de l’évolution : les défis à venir », Sep 2014, Roscoff, France. ⟨hal-01134476⟩

Books1 document

  • Dominique Joly, Christoph Grunau. Prospective Épigénétique en Ecologie et Environnement de l’Institut Ecologie et Environnement du CNRS. Les Cahiers Prospectives (CNRS-INEE) n°8 Novembre 80 pages.. 2018. ⟨hal-02366517⟩

Book sections2 documents

  • Francesca Merlin, Antonine Nicoglou, Christoph Grunau, Danchin Etienne. Qu'est-ce que l'épigénétique ?. D Joly & C Grunau (dir.) Prospective épigénétique écologie & évolution, Une prospective de l'Institut écologie et environnement, N. 8 - Novembre 2018., 2018. ⟨hal-02926493⟩
  • Christoph Grunau. Methylation mapping in humans. Epigenetics: linking genotype and phenotype in development and evolution, University of California Press, pp.70-86, 2011, 978-0-520-94882-2. ⟨hal-00941929⟩

Other publications1 document

  • Ronaldo de Carvalho Augusto, Aki Minoda, Christoph Grunau. A simple ATAC-seq protocol for population epigenetics. 2019. ⟨hal-02428832⟩

Preprints, Working Papers, ...1 document

  • Ronaldo de Carvalho Augusto, Aki Minoda, Oliver Rey, Céline Cosseau, Cristian Chaparro, et al.. Chromatin structure changes in Daphnia populations upon exposure to environmental cues – or – The discovery of Wolterecks “Matrix”.. 2019. ⟨hal-02366511⟩