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Christine Leroux
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Documents
Identifiants chercheurs
- christine-leroux
- 0000-0001-6835-3978
- Google Scholar : https://scholar.google.com/citations?user=FdeOzCAAAAAJ&hl=fr
- IdRef : 193885018
Présentation
Christine Leroux (women, PhD, HDR) is a research director from INRAE, the French national institute for research in agriculture, nutrition and environment. After obtaining her PhD in Molecular Genetics (University of Orsay-Paris XI, France) in 1992, Christine started to work at INRA on milk components biosynthesis and secretion in dairy ruminants. She studies the effects of different factors (mainly genetics and nutritional) influencing mammary gland functioning during lactation. Christine’s research aims to improve nutritional quality of milk for consumers and to identify indicators of animal metabolism and health using strategies of nutrigenomics. She firstly studied the effects of genetics polymorphism on protein synthesis, and then she worked on effects of ruminant nutrition on mammary and in a lesser extent on adipose tissues gene expression associated with milk fat composition. More recently, she initiated studies on microRNA and their nutritional regulation in mammary gland. She was visiting researcher scientist at University of California Davis (2017-2019) where she investigated the potential role of milk microRNA as a food source bioactive and contributor to human health. End of 2020, she had 5383 citations and an h-index of 41 referenced by Google Scholar. She participated to 15 national and international research projects. She has 8 years of experience of management of research groups (more than 15 persons) and of a transcriptomic platform, and she has supervised over 26 students (both undergraduates and graduates).
Publications
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MiRNome variations in milk fractions during feed restrictions of different intensities in dairy cowsBMC Genomics, 2023, 24 (1), pp.680. ⟨10.1186/s12864-023-09769-5⟩
Article dans une revue
hal-04284310v1
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Milk proteins as a feed restriction signature indicating the metabolic adaptation of dairy cowsScientific Reports, 2022, 12 (1), pp.18886. ⟨10.1038/s41598-022-21804-1⟩
Article dans une revue
hal-03860146v1
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L’épigénétique et la construction du phénotype chez le bovinINRAE Productions Animales, 2020, 33 (2), pp.109-124. ⟨10.20870/productions-animales.2020.33.2.4477⟩
Article dans une revue
hal-02947903v1
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Effects of polyunsaturated fatty acids from plant oils and algae on milk fat yield and composition are associated with mammary lipogenic and SREBF1 gene expressionAnimal, 2012, 6 (12), pp.1961-1972. ⟨10.1017/S1751731112000845⟩
Article dans une revue
hal-02652522v1
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Validation of HappyMoo MIR energy balance models on external datasets with feeding restriction74. Annual meeting of the european federation of animal science (EAAP), EAAP, Aug 2023, Lyon, France. pp.1029
Communication dans un congrès
hal-04195776v1
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Feed restriction affects protein and microRNA levels in dairy cows' milk72. Annual meeting of the european federation of animal science (EAAP), Aug 2021, Davos, Switzerland. pp.620
Communication dans un congrès
hal-03318595v1
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Impact d’une restriction alimentaire sur les miRNome et protéome du lait chez la vache laitièreGlande mammaire lait / Galactinnov, Nov 2021, En ligne, France
Communication dans un congrès
hal-03747713v1
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Signatures épigénétiques associées à l’état physiologique, nutritionnel et pathologique chez la vache laitière en postpartum3. Journée de Séminaires du Département Phase sur l'Epigénétique EpiPhase, May 2017, Jouy-en-Josas, France. 1 p
Communication dans un congrès
hal-01605492v1
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Vers une représentation conceptuelle minimale du fonctionnement intégratif verticale de la glande mammaireJournées d’Animation des Crédits Incitatifs du Département de Physiologie Animale et Systèmes d’Elevage (JACI Phase), Oct 2010, Tours, France
Communication dans un congrès
hal-01173652v1
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Integrative biology of the mammary function and plasticity of milk fatdu séminaire AgenaeGenanimal, 15-16 octobre 2007, Oct 2007, Dourdan, France
Communication dans un congrès
hal-02751021v1
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