Accéder directement au contenu

Christine Leroux

16
Documents
Identifiants chercheurs

Présentation

Christine Leroux (women, PhD, HDR) is a research director from INRAE, the French national institute for research in agriculture, nutrition and environment. After obtaining her PhD in Molecular Genetics (University of Orsay-Paris XI, France) in 1992, Christine started to work at INRA on milk components biosynthesis and secretion in dairy ruminants. She studies the effects of different factors (mainly genetics and nutritional) influencing mammary gland functioning during lactation. Christine’s research aims to improve nutritional quality of milk for consumers and to identify indicators of animal metabolism and health using strategies of nutrigenomics. She firstly studied the effects of genetics polymorphism on protein synthesis, and then she worked on effects of ruminant nutrition on mammary and in a lesser extent on adipose tissues gene expression associated with milk fat composition. More recently, she initiated studies on microRNA and their nutritional regulation in mammary gland. She was visiting researcher scientist at University of California Davis (2017-2019) where she investigated the potential role of milk microRNA as a food source bioactive and contributor to human health. End of 2020, she had 5383 citations and an h-index of 41 referenced by Google Scholar. She participated to 15 national and international research projects. She has 8 years of experience of management of research groups (more than 15 persons) and of a transcriptomic platform, and she has supervised over 26 students (both undergraduates and graduates).

Publications

jean-francois-hocquette
"mubonnetumrh"

Image analysis and data normalization procedures are crucial for microarray analyses

Ali Kpatcha Kadanga , Christine Leroux , Muriel Bonnet , Stéphanie Chauvet , Bruno Meunier
Gene Regulation and Systems Biology, 2008, 2, pp.107-112
Article dans une revue hal-02654575v1

Glucose-6-phosphate dehydrogenase and leptin are related to marbling differences among Limousin and Angus or Japanese Black x Angus steers

Muriel Bonnet , Yannick Faulconnier , Christine Leroux , Catherine C. Jurie , Isabelle Cassar-Malek
Journal of Animal Science, 2007, 85 (11), pp.2882-2894
Article dans une revue hal-02653399v1

Adipocyte fatty acid-binding protein and mitochondrial enzyme activities in muscles as relevant indicators of marbling in cattle

Catherine C. Jurie , Isabelle Cassar-Malek , Muriel Bonnet , Christine Leroux , Dominique Bauchart
Journal of Animal Science, 2007, 85 (10), pp.2660-2669
Article dans une revue hal-02656889v1

Nutritional status induces divergent variations of GLUT4 protein content, but not lipoprotein lipase activity, between adipose tissues and muscles in adult cattle

Muriel Bonnet , Yannick Faulconnier , Jean-François J.-F. Hocquette , Francois Bocquier , Christine Leroux
British Journal of Nutrition, 2004, 92 (4), pp.617-625. ⟨10.1079/BJN20041240⟩
Article dans une revue hal-02680426v1

Lipoprotein lipase activity and mRNA are up-regulated by refeeding in adipose tissue and cardiac muscle of sheep

Muriel Bonnet , Christine Leroux , Yannick Faulconnier , Jean-François J.-F. Hocquette , Francois Bocquier
Journal of Nutrition, 2000, 130, pp.749-756
Article dans une revue hal-02694885v1
Image document

Régulation du métabolisme lipidique des tissus adipeux et musculaires chez le ruminant. Effets du niveau alimentaire et de la photopériode

Yannick Faulconnier , Muriel Bonnet , Francois Bocquier , Christine Leroux , Jean-François J.-F. Hocquette
Productions Animales, 1999, 12 (4), pp.287-300
Article dans une revue hal-02694594v1
Image document

Messenger RNAs encoding lipoprotein lipase, fatty acid synthase and hormone-sensitive lipase in the adipose tissue of underfed-refed ewes and cows

Muriel Bonnet , Yannick Faulconnier , Jeanne Fléchet , Jean-François J.-F. Hocquette , Christine Leroux
Reproduction Nutrition Development, 1998, 38 (3), pp.297-307
Article dans une revue hal-00900209v1

Messenger RNAs encoding lipoprotein lipase, fatty acid synthase and hormone-sensitive lipase in the adipose tissue of underfed-refed ewes and cows

Muriel Bonnet , Yannick Faulconnier , Jean-François J.-F. Hocquette , Christine Leroux , Dominique Langin
Reproduction Nutrition Development, 1998, 38 (3), pp.297-307
Article dans une revue hal-02698559v1

Study of lipoprotein lipase mRNAs in ovine adipose tissue by quantitative fluorescence polymerase chain reaction

Muriel Bonnet , Christine Leroux , J.P. Furet , Patrice Martin , Fabienne Le Provost
Reproduction Nutrition Development, 1997, 37 (3), pp.371
Article dans une revue hal-02685426v1

Genomic tools to analyse bovine muscle and adipose tissues transcriptomes

Ali Kpatcha Kadanga , Christine Leroux , Muriel Bonnet , Isabelle Cassar-Malek , Jean-François J.-F. Hocquette
2. International Symposium on Energy and Protein Metabolism and Nutrition (ISEP 2007), Sep 2007, Vichy, France
Communication dans un congrès hal-02753466v1

Diet and physiological state influence gene expression in herbivores

Isabelle Cassar-Malek , Christine Leroux , Dominique Gruffat , Muriel Bonnet , Laurence Bernard
7. International Symposium on the Nutrition of Herbivores, Sep 2007, Beijing, China
Communication dans un congrès hal-02750923v1

L'activité de la glucose-6-phosphate deshydrogenase est liée aux différences d'adiposite tissulaires et raciales chez le bovin en croissance

Muriel Bonnet , Yannick Faulconnier , Christine Leroux , Catherine C. Jurie , Isabelle Cassar-Malek
1ères Journées d'Animation Scientifique du Département de Physiologie Animale et Systèmes d'Elevage, Mar 2005, Tours, France
Communication dans un congrès hal-02759104v1

Glucose-6-Phosphate dehydrogenase and leptin are linked to marbling differences between Limousin and angus or japanese black x angus steers

Muriel Bonnet , Yannick Faulconnier , Christine Leroux , Catherine C. Jurie , Isabelle Cassar-Malek
56. Annual Meeting of the European Association for Animal Production (EAAP), Jun 2005, Uppsala, Sweden
Communication dans un congrès hal-02760645v1

ROGER : Un Répertoire Ordonné de Gènes pour l'analyse de l'Expression génique chez les Ruminants. Application à l'identification de marqueurs de la différenciation dans le muscle, le tissu adipeux, l'embryon et la glande mammaire

Patrice Martin , Jean-François J.-F. Hocquette , Isabelle Hue , Christine Leroux , Sophie Pollet
10. Rencontres autour des Recherches sur les Ruminants, Dec 2003, Paris, France
Communication dans un congrès hal-02763483v1

Lipogenesis in subcutaneous adipose tissue and in oxidative or glycolytic muscles from Angus, Black Japanese x Angus and Limousin

Muriel Bonnet , Yannick Faulconnier , Jean-François J.-F. Hocquette , Christine Leroux , P. Boulesteix
Progress in research on energy and protein metabolism, Sep 2003, Rostock-Warnemünde, Germany
Communication dans un congrès hal-02761029v1

Study of lipoprotein lipase mRNAs in ovine adipose tissue by quantitative fluorescence polymerase chain reaction

Muriel Bonnet , Christine Leroux , J.P. Furet , Patrice Martin , Fabienne Le Provost
Annual Symposium on Animal and Human Nutrition, Oct 1996, Nantes, France
Communication dans un congrès hal-02835538v1