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Christine Leroux
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Documents
Identifiants chercheurs
- christine-leroux
- 0000-0001-6835-3978
- Google Scholar : https://scholar.google.com/citations?user=FdeOzCAAAAAJ&hl=fr
- IdRef : 193885018
Présentation
Christine Leroux (women, PhD, HDR) is a research director from INRAE, the French national institute for research in agriculture, nutrition and environment. After obtaining her PhD in Molecular Genetics (University of Orsay-Paris XI, France) in 1992, Christine started to work at INRA on milk components biosynthesis and secretion in dairy ruminants. She studies the effects of different factors (mainly genetics and nutritional) influencing mammary gland functioning during lactation. Christine’s research aims to improve nutritional quality of milk for consumers and to identify indicators of animal metabolism and health using strategies of nutrigenomics. She firstly studied the effects of genetics polymorphism on protein synthesis, and then she worked on effects of ruminant nutrition on mammary and in a lesser extent on adipose tissues gene expression associated with milk fat composition. More recently, she initiated studies on microRNA and their nutritional regulation in mammary gland. She was visiting researcher scientist at University of California Davis (2017-2019) where she investigated the potential role of milk microRNA as a food source bioactive and contributor to human health. End of 2020, she had 5383 citations and an h-index of 41 referenced by Google Scholar. She participated to 15 national and international research projects. She has 8 years of experience of management of research groups (more than 15 persons) and of a transcriptomic platform, and she has supervised over 26 students (both undergraduates and graduates).
Publications
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MiRNome variations in milk fractions during feed restrictions of different intensities in dairy cowsBMC Genomics, 2023, 24 (1), pp.680. ⟨10.1186/s12864-023-09769-5⟩
Article dans une revue
hal-04284310v1
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Sunflower oil supplementation affects the expression of miR-20a-5p and miR-142-5p in the lactating bovine mammary glandPLoS ONE, 2017, 12 (12), pp.e0185511. ⟨10.1371/journal.pone.0185511⟩
Article dans une revue
hal-02617650v1
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Food deprivation affects the miRNome in the lactating goat mammary glandPLoS ONE, 2015, 10 (10), 20 p. ⟨10.1371/journal.pone.0140111⟩
Article dans une revue
hal-02630964v1
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Characterisation and comparison of lactating mouse and bovine mammary gland miRNomesPLoS ONE, 2014, 9 (3), pp.e91938. ⟨10.1371/journal.pone.0091938⟩
Article dans une revue
hal-01193833v1
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Impact d’une restriction alimentaire sur les miRNome et protéome du lait chez la vache laitièreGlande mammaire lait / Galactinnov, Nov 2021, En ligne, France
Communication dans un congrès
hal-03747713v1
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Impact des microARNs sur la lactation et la régulation nutritionnelle de leur expression dans la glande mammaire2. Réunion d'Animation épiPHASE, Institut National de Recherche Agronomique (INRA). UAR Département Physiologie Animale et Systèmes d'Elevage (0558)., Mar 2016, Saint-Pée-sur-Nivelle, France
Communication dans un congrès
hal-02795094v1
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Nutritional regulation of microRNAs in the lactating goat mammary glandGordon Research Conference on Mammary Gland Biology, Jun 2014, Lucca, Italy
Communication dans un congrès
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Characterisation and comparison of lactating mouse and bovine mammary gland miRNomesGordon Research Conference on Mammary Gland Biology, Jun 2014, Lucca, Italy. 1 p
Communication dans un congrès
hal-01193894v1
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Species comparison of lactating mammary gland miRNomes: to the identification of conserved lactation-related microRNA12th International Meeting - Cellular aspects of mRNA fate, Université Pierre et Marie Curie - Paris 6 (UPMC). FRA., Jun 2013, Paris, France. pp.1
Communication dans un congrès
hal-01001041v1
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