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AMPK activation protects from neuronal dysfunction and vulnerability across nematode, cellular and mouse models of Huntington's disease
Rafael P. Vazquez-Manrique
,
Francesca Farina
,
Karine Cambon
,
Maria Dolores Sequedo
,
Alex J. Parker
,
et al.
Article dans une revue
hal-01545502v1
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The stress response factor daf-16 /FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease
Francesca Farina
,
Emmanuel Lambert
,
Lucie Commeau
,
François-Xavier Lejeune
,
Nathalie Roudier
,
et al.
Article dans une revue
hal-01545500v1
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Cell-Type-Specific Gene Expression Profiling in Adult Mouse Brain Reveals Normal and Disease-State Signatures
Nicolas Merienne
,
Cécile Meunier
,
Anne Schneider
,
Jonathan Seguin
,
Satish Nair
,
et al.
Article dans une revue
hal-02087719v1
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Precision machine learning to understand micro-RNA regulation in neurodegenerative diseases
Lucile Mégret
,
Cloé Mendoza
,
Maialen Arrieta Lobo
,
Emmanuel Brouillet
,
Thi-Thanh-Yen Nguyen
,
et al.
Article dans une revue
hal-03869363v1
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Identification of Modulators of the C. elegans Aryl Hydrocarbon Receptor and Characterization of Transcriptomic and Metabolic AhR-1 Profiles
Lucie Larigot
,
Linh-Chi Bui
,
Marine de Bouvier
,
Ophélie Pierre
,
Grégory Pinon
,
et al.
Article dans une revue
hal-03745310v1
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Cdc42-interacting protein 4 binds to huntingtin: Neuropathologic and biological evidence for a role in Huntington's disease
Sébastien Holbert
,
Alpaslan Dedeoglu
,
Sandrine Humbert
,
Frédéric Saudlou
,
Robert J. Ferrante
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2003, 100 (5), pp.2712 - 2717. ⟨10.1073/pnas.0437967100⟩
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Pathways to decoding the clinical potential of stress response FOXO-interaction networks for Huntington's disease: of gene prioritization and context dependence
Frederic Parmentier
,
Francois-Xavier Lejeune
,
Christian Neri
Article dans une revue
hal-01545516v1
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CA150 expression delays striatal cell death in overexpression and knock-in conditions for mutant huntingtin neurotoxicity
Margarita Arango
,
Sébastien Holbert
,
Dania Zala
,
Emmanuel Brouillet
,
James Pearson
,
et al.
Article dans une revue
hal-02666883v1
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The Oxygen Paradox, the French Paradox, and age-related diseases
Joanna M. S. Davies
,
Josiane Cillard
,
Bertrand Friguet
,
Enrique Cadenas
,
Jean Cadet
,
et al.
Article dans une revue
hal-01718093v1
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Optimal transport-based machine learning to match specific patterns: application to the detection of molecular regulation patterns in omics data
Thi Thanh Yen Nguyen
,
Warith Harchaoui
,
Lucile Mégret
,
Cloe Mendoza
,
Olivier Bouaziz
,
et al.
2023
Pré-publication, Document de travail
hal-03293786v3
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Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease
Patrizia A Chiesa
,
Enrica Cavedo
,
Andrea Vergallo
,
Simone Lista
,
Marie-Claude Potier
,
et al.
Article dans une revue
hal-02368904v1
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CAG/CTG and CGG/GCC repeats in human brain reference cDNAs: Outcome in searching for new dynamic mutations
Véronique Albanèse
,
Sébastien Holbert
,
Claudine Saada
,
Sebastian Meier-Ewert
,
Anne Sophie Lebre
,
et al.
Article dans une revue
istex
hal-02696172v1
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Integration of beta-Catenin, Sirtuin, and FOXO Signaling Protects from Mutant Huntingtin Toxicity
J. Alex Parker
,
Rafael P. Vazquez-Manrique
,
Cendrine Tourette
,
Francesca Farina
,
Nicolas Offner
,
et al.
Article dans une revue
hal-01545520v1
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Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice
M. Achour
,
S. Le Gras
,
C. Keime
,
F. Parmentier
,
F. Lejeune
,
et al.
Article dans une revue
hal-02106606v1
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Biosensing Extracellular Vesicle Subpopulations in Neurodegenerative Disease Conditions
Yacine Mazouzi
,
Fadoua Sallem
,
Francesca Farina
,
Alexis Loiseau
,
Natayme Rocha Tartaglia
,
et al.
Article dans une revue
hal-03791750v1
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Combining feature selection and shape analysis uncovers precise rules for miRNA regulation in Huntington’s disease mice
Lucile Mégret
,
Satish Sasidharan Nair
,
Julia Dancourt
,
Jeff Aaronson
,
Jim Rosinski
,
et al.
Article dans une revue
inserm-02512089v1
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Association between Cognitive Status before Surgery and Outcomes in Elderly Patients with Hip Fracture in a Dedicated Orthogeriatric Care Pathway
Lorene Zerah
,
Judith Cohen-Bittan
,
Mathieu Raux
,
Anthony Meziere
,
Cendrine Tourette
,
et al.
Article dans une revue
hal-03970430v1
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Plasma tau correlates with basal forebrain atrophy rates in people at risk for Alzheimer disease
Enrica Cavedo
,
Simone Lista
,
Marion Houot
,
Andrea Vergallo
,
Michel Grothe
,
et al.
Article dans une revue
hal-03769491v1
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Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
Clotilde Thery
,
Kenneth Witwer
,
Elena Aikawa
,
Maria Jose Alcaraz
,
Johnathon Anderson
,
et al.
Article dans une revue
hal-02323217v1
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[C. elegans as a model for human inherited degenerative diseases]
Laurent Ségalat
,
Christian Néri
Médecine/Sciences, 2003, 19 (12), pp.1218-25
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hal-00194459v1
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Genetic and pharmacological suppression of polyglutamine-dependent neuronal dysfunction in Caenorhabditis elegans
J. Alex Parker
,
Sébastien Holbert
,
Emmanuel Lambert
,
Salima Abderrahmane
,
Christian Néri
Article dans une revue
istex
hal-02675749v1
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Biomarkers of vascular dysfunction and cognitive decline in patients with Alzheimer’s disease: no evidence for association in elderly subjects
Alice Breining
,
Jean-Sébastien Silvestre
,
Bénédicte Dieudonné
,
José Vilar
,
Véronique Faucounau
,
et al.
Article dans une revue
hal-01383389v1
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Shape deformation analysis reveals the temporal dynamics of cell-type-specific homeostatic and pathogenic responses to mutant huntingtin
Lucile Mégret
,
Barbara Gris
,
Satish Sasidharan Nair
,
Jasmin Cevost
,
Mary Wertz
,
et al.
Article dans une revue
hal-03151218v1
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C-elegans neurons jettison protein aggregates and mitochondria under neurotoxic stress
Ilija Melentijevic
,
Marton L. Toth
,
Meghan L. Arnold
,
Ryan J. Guasp
,
Girish Harinath
,
et al.
Article dans une revue
hal-01545495v1
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NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease
Mahmoud A. Pouladi
,
Elsa Brillaud
,
Yuanyun Xie
,
Paola Conforti
,
Rona K. Graham
,
et al.
Article dans une revue
istex
hal-01545519v1
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Revolution of Alzheimer Precision Neurology. Passageway of Systems Biology and Neurophysiology
Harald Hampel
,
Nicola Toschi
,
Claudio Babiloni
,
Filippo Baldacci
,
Keith L Black
,
et al.
Article dans une revue
hal-01910402v1
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Sirtuin inhibition protects from the polyalanine muscular dystrophy protein PABPN1
Helene Catoire
,
Matthieu Y. Pasco
,
Aida Abu-Baker
,
Sébastien Holbert
,
Cendrine Tourette
,
et al.
Article dans une revue
hal-02655510v1
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Association of plasma YKL-40 with brain amyloid-β levels, memory performance, and sex in subjective memory complainers
Andrea Vergallo
,
Simone Lista
,
Pablo Lemercier
,
Patrizia A. Chiesa
,
Henrik Zetterberg
,
et al.
Article dans une revue
hal-03491473v1
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Role and therapeutic potential of the pro-longevity factor FOXO and its regulators in neurodegenerative disease
Christian Neri
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hal-01545518v1
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Morphological remodeling of C. elegans neurons during aging is modified by compromised protein homeostasis
Elena M. Vayndorf
,
Courtney Scerbak
,
Skyler Hunter
,
Jason R. Neuswanger
,
Marton Toth
,
et al.
Article dans une revue
hal-01545501v1
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