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	Pour les 47 documents Envoyer sur ORCID RSS ATOM Exporter BibTeX XML-TEI CSV RTF EndNote PDF HTML Export avancé	Page : Page précédente 1 2 Page suivante	triés par Pertinence Auteur A→Z Auteur Z→A Titre A→Z Titre Z→A Date de publication croissante Date de publication décroissante Date de dépôt croissante Date de dépôt décroissante

		Macrocyclisation in situ by confinement: proof of concept and application to the design of new macrocyclic inhibitors of the InhA enzyme Melina Chebaiki , Christian Lherbet , Laurent Maveyraud , Lionel Mourey SECO 59, 16-20 mai 2022, May 2022, La Londe-Les-Maures, France Communication dans un congrès hal-03690361v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthesis of Methylerythritol Phosphate Analogues and Their Evaluation as Alternate Substrates for IspDF and IspE from Agrobacterium tumefaciens Sergiy Krasutsky , Marek Urbansky , Chad Davis , Christian Lherbet , Robert Coates , et al. Journal of Organic Chemistry, 2014, 79 (19), pp.9170-9178. ⟨10.1021/jo501529k⟩ Article dans une revue hal-02064012v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		A revisited structure for nitrosoprodenafil from NMR, mass spectrometry, X-ray and hydrolysis data Robert Martino , Christophe Menendez , Stéphane Balayssac , Nathalie Martins-Froment , Christian Lherbet , et al. Journal of Pharmaceutical and Biomedical Analysis, 2017, 135, pp.31-49. ⟨10.1016/j.jpba.2016.12.011⟩ Article dans une revue hal-02060162v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach Aurélien Chollet , Lionel Mourey , Christian Lherbet , Alexandra Delbot , Sylviane Julien , et al. Journal of Structural Biology, 2015, 190, pp.328 - 337. ⟨10.1016/j.jsb.2015.04.008⟩ Article dans une revue hal-03002973v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Evaluation of heteroatom-rich derivatives as antitubercular agents with InhA inhibition properties Bachar Rébat Moulkrere , Beatrice Orena , Giorgia Mori , Nathalie Saffon-Merceron , Frédéric Rodriguez , et al. Medicinal Chemistry Research, 2018, 27 (1), pp.308-320. ⟨10.1007/s00044-017-2064-x⟩ Article dans une revue hal-02058656v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Design and synthesis of 9 H -fluorenone based 1,2,3-triazole analogues as Mycobacterium tuberculosis InhA inhibitors Amaroju Suresh , Singireddi Srinivasarao , Napiórkowska Agnieszka , Augustynowicz-Kopeć Ewa , Mallika Alvala , et al. Chemical Biology & Drug Design, 2018, 91 (6), pp.1078-1086. ⟨10.1111/cbdd.13127⟩ Article dans une revue hal-02018145v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases Alexandre Faille , Sabine Gavalda , Nawel Slama , Christian Lherbet , Laurent Maveyraud , et al. Journal of Molecular Biology, 2017, 429 (47), pp.1554 - 1569. ⟨10.1016/j.jmb.2017.03.026⟩ Article dans une revue hal-03002100v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Discovery of hydrazone containing thiadiazoles as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors Hilal Doğan , Şengül Dilem Doğan , Miyase Gözde Gündüz , Vagolu Siva Krishna , Christian Lherbet , et al. European Journal of Medicinal Chemistry, 2020, pp.112035. ⟨10.1016/j.ejmech.2020.112035⟩ Article dans une revue hal-02438076v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Discovery of new diaryl ether inhibitors against Mycobacterium tuberculosis targeting the minor portal of InhA Mélina Chebaiki , Evelyne Delfourne , Rasoul Tamhaev , Saïda Danoun , Frédéric Rodriguez , et al. European Journal of Medicinal Chemistry, 2023, 259, pp.115646. ⟨10.1016/j.ejmech.2023.115646⟩ Article dans une revue hal-04244940v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Chemical synthesis, molecular modeling and pharmacophore mapping of new pyrrole derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth Shrinivas Joshi , S. Kumar , Sonali Patil , M. Vijayakumar , Venkatarao Kulkarni , et al. Medicinal Chemistry Research, 2019, 28 (11), pp.1838-1863. ⟨10.1007/s00044-019-02418-1⟩ Article dans une revue hal-03035954v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthesis of 3-heteryl substituted pyrrolidine-2,5-diones via catalytic Michael reaction and evaluation of their inhibitory activity against InhA and Mycobacterium tuberculosis Tetiana Matviiuk , Giorgia Mori , Christian Lherbet , Frédéric Rodriguez , Maria Rosalia Pasca , et al. European Journal of Medicinal Chemistry, 2014, 71, pp.46-52. ⟨10.1016/j.ejmech.2013.10.069⟩ Article dans une revue hal-02063615v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Discovery of novel N-methyl carbazole tethered rhodanine derivatives as direct inhibitors of Mycobacterium tuberculosis InhA Mahamadhanif S. Shaikh , Ashish M. Kanheda , Chandrasekaran Balakumar , Mahesh B. Palkar , Nikhil Agrawal , et al. Bioorganic and Medicinal Chemistry Letters, 2019, 29, pp.2338-2344. ⟨10.1016/j.bmcl.2019.06.015⟩ Article dans une revue hal-03038682v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		LiAlH 4 -Promoted Tandem Reduction/Oxidation of Fluorenyl Derivatives under Air Tetiana Matviiuk , Christophe Menendez , Chantal Carayon , Nathalie Saffon , Zoia Voitenko , et al. European Journal of Organic Chemistry, 2014, 2014 (29), pp.6538-6546. ⟨10.1002/ejoc.201402642⟩ Article dans une revue istex hal-02063832v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Design, synthesis, and evaluation of potential dual-target inhibitors of Mycobacterium tuberculosis InhA and HadA and their antitubercular activities Lorena Valentin , Rasoul Tamhaev , Joelle Azema , Lionel Mourey , Christian Lherbet ACS Spring Meeting 2023, Mar 2023, Indianapolis (IN), United States Poster de conférence hal-04192586v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		In situ click chemistry for the formation of novel InhA inhibitors of Mycobacterium tuberculosis Melina Chebaiki , Evelyne Delfourne , Saïda Danoun , Isabelle Fabing , Laurent Maveyraud , et al. Journée de Chimie du Grand Sud-Ouest, Jul 2022, Toulouse, France Poster de conférence hal-03812172v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		A mesoporous metal–organic framework used to sustainably release copper( ii ) into reducing aqueous media to promote the CuAAC click reaction Pascal Hoffmann , Christian Lherbet , Isabelle Fabing , Marie-Claire Barthélémy , Yann Borjon-Piron , et al. RSC Advances, 2022, 12 (41), pp.26825-26833. ⟨10.1039/d2ra04298c⟩ Article dans une revue hal-03785805v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		An overview on crystal structures of InhA protein: Apo-form, in complex with its natural ligands and inhibitors Aurélien Chollet , Laurent Maveyraud , Christian Lherbet , Vania Bernardes-Génisson European Journal of Medicinal Chemistry, 2018, 146, pp.318-343. ⟨10.1016/j.ejmech.2018.01.047⟩ Article dans une revue hal-01952876v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthesis, characterization and antitubercular activities of novel pyrrolyl hydrazones and their Cu-complexes Shrinivas Joshi , Devendra Kumar , Sheshagiri Dixit , Nageshwar Tigadi , Uttam More , et al. European Journal of Medicinal Chemistry, 2016, 121, pp.21-39. ⟨10.1016/j.ejmech.2016.05.025⟩ Article dans une revue hal-02060618v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: toward in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis Aurélien Chollet , Jean-Luc Stigliani , Maria Rosalia Pasca , Giorgia Mori , Christian Lherbet , et al. Chemical Biology and Drug Design, 2016, 88 (5), pp.740-755. ⟨10.1111/cbdd.12804⟩ Article dans une revue istex hal-01929908v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity Paulo F. M. Oliveira , Brigitte Guidetti , Alain Chamayou , Christiane André-Barrès , Jan Madacki , et al. Molecules, 2017, 22 (9), art.1457 - 27p. ⟨10.3390/molecules22091457⟩ Article dans une revue hal-01631582v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Chemical synthesis and in silico molecular modeling of novel pyrrolyl benzohydrazide derivatives: Their biological evaluation against enoyl ACP reductase (InhA) and Mycobacterium tuberculosis Shrinivas Joshi , Uttam More , Sheshagiri Dixit , Sunil Balmi , Basavaraj Kulkarni , et al. Bioorganic Chemistry, 2017, 75, pp.181-200. ⟨10.1016/j.bioorg.2017.09.008⟩ Article dans une revue hal-02060545v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Vers de nouveaux inhibiteurs d'InhA découverts par cristallographie combinatoire dynamique aux rayons X R. Tamhaev , Laurent Maveyraud , Lionel Mourey , Christian Lherbet 2ème Journées Scientifique du GDR ChemBio– 34ieme Journée Chimie - biologie - Santé, Jun 2022, Toulouse, France Poster de conférence hal-03685340v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthesis, antimycobacterial screening and ligand-based molecular docking studies on novel pyrrole derivatives bearing pyrazoline, isoxazole and phenyl thiourea moieties Shrinivas Joshi , Sheshagiri Dixit , M.N. Kirankumar , Tejraj Aminabhavi , K.V.S.N. Raju , et al. European Journal of Medicinal Chemistry, 2016, 107, pp.133-152. ⟨10.1016/j.ejmech.2015.10.047⟩ Article dans une revue hal-02060628v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis Asma Farjallah , Laurent Chiarelli , Martin Forbak , Giulia Degiacomi , Mathieu Danel , et al. ACS Infectious Diseases, 2021, 7 (3), pp.552-565. ⟨10.1021/acsinfecdis.0c00325⟩ Article dans une revue hal-03209886v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthesis of α-Keto-1,2,3-triazoles Through Copper Iodide Catalyzed Oxygenation Swantje Nawratil , Maria Grypioti , Christophe Menendez , Sonia Mallet-Ladeira , Christian Lherbet , et al. European Journal of Organic Chemistry, 2014, 2014 (3), pp.654-659. ⟨10.1002/ejoc.201301035⟩ Article dans une revue istex hal-02063637v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Design and synthesis of thiourea-based derivatives as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors Şengül Dilem Doğan , Miyase Gözde Gündüz , Hilal Doğan , Vagolu Siva Krishna , Christian Lherbet , et al. European Journal of Medicinal Chemistry, 2020, 199, pp.112402. ⟨10.1016/j.ejmech.2020.112402⟩ Article dans une revue hal-02863650v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		In Silico Repositioning of Cannabigerol as a Novel Inhibitor of the Enoyl Acyl Carrier Protein (ACP) Reductase (InhA) Luca Pinzi , Christian Lherbet , Michel Baltas , Federica Pellati , Giulio Rastelli Molecules, 2019, 24 (14), pp.E2567. ⟨10.3390/molecules24142567⟩ Article dans une revue hal-02326666v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Synthesis, characterization, anti-tuberculosis activity and molecular modeling studies of thiourea derivatives bearing aminoguanidine moiety Michael Tapera , Hüseyin Kekeçmuhammed , Kader Sahin , Vagolu Siva Krishna , Christian Lherbet , et al. Journal of Molecular Structure, 2022, 1270, pp.133899. ⟨10.1016/j.molstruc.2022.133899⟩ Article dans une revue hal-03797382v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		Phosphopantetheinyl transferases as drug targets for the treatment of infectious diseases Claire Blanger , Christian Lherbet , Christophe Menendez , Michel Baltas , Stéphanie Ballereau , et al. Congress SFC 2018 Chemistry and Life Symposium, Jun 2018, Montpellier, France Poster de conférence hal-02337483v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More
		La chimie click in situ pour la formation de nouveaux inhibiteurs d’InhA de Mycobacterium tuberculosis Melina Chebaiki , Lionel Mourey , L. Maveyraud , Christian Lherbet GDR - ChemBiologie, Jun 2022, Toulouse, France Communication dans un congrès hal-03811107v1	Envoyer sur ORCID Exporter BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite Export avancé Partager Gmail Facebook X LinkedIn More

Filtrer vos résultats

Macrocyclisation in situ by confinement: proof of concept and application to the design of new macrocyclic inhibitors of the InhA enzyme

Synthesis of Methylerythritol Phosphate Analogues and Their Evaluation as Alternate Substrates for IspDF and IspE from Agrobacterium tumefaciens

A revisited structure for nitrosoprodenafil from NMR, mass spectrometry, X-ray and hydrolysis data

Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach

Evaluation of heteroatom-rich derivatives as antitubercular agents with InhA inhibition properties

Design and synthesis of 9 H -fluorenone based 1,2,3-triazole analogues as Mycobacterium tuberculosis InhA inhibitors

Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases

Discovery of hydrazone containing thiadiazoles as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors

Discovery of new diaryl ether inhibitors against Mycobacterium tuberculosis targeting the minor portal of InhA

Chemical synthesis, molecular modeling and pharmacophore mapping of new pyrrole derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth

Synthesis of 3-heteryl substituted pyrrolidine-2,5-diones via catalytic Michael reaction and evaluation of their inhibitory activity against InhA and Mycobacterium tuberculosis

Discovery of novel N-methyl carbazole tethered rhodanine derivatives as direct inhibitors of Mycobacterium tuberculosis InhA

LiAlH 4 -Promoted Tandem Reduction/Oxidation of Fluorenyl Derivatives under Air

Design, synthesis, and evaluation of potential dual-target inhibitors of Mycobacterium tuberculosis InhA and HadA and their antitubercular activities

In situ click chemistry for the formation of novel InhA inhibitors of Mycobacterium tuberculosis

A mesoporous metal–organic framework used to sustainably release copper( ii ) into reducing aqueous media to promote the CuAAC click reaction

An overview on crystal structures of InhA protein: Apo-form, in complex with its natural ligands and inhibitors

Synthesis, characterization and antitubercular activities of novel pyrrolyl hydrazones and their Cu-complexes

Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: toward in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis

Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity

Chemical synthesis and in silico molecular modeling of novel pyrrolyl benzohydrazide derivatives: Their biological evaluation against enoyl ACP reductase (InhA) and Mycobacterium tuberculosis

Vers de nouveaux inhibiteurs d'InhA découverts par cristallographie combinatoire dynamique aux rayons X

Synthesis, antimycobacterial screening and ligand-based molecular docking studies on novel pyrrole derivatives bearing pyrazoline, isoxazole and phenyl thiourea moieties

A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis

Synthesis of α-Keto-1,2,3-triazoles Through Copper Iodide Catalyzed Oxygenation

Design and synthesis of thiourea-based derivatives as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors

In Silico Repositioning of Cannabigerol as a Novel Inhibitor of the Enoyl Acyl Carrier Protein (ACP) Reductase (InhA)

Synthesis, characterization, anti-tuberculosis activity and molecular modeling studies of thiourea derivatives bearing aminoguanidine moiety

Phosphopantetheinyl transferases as drug targets for the treatment of infectious diseases

La chimie click in situ pour la formation de nouveaux inhibiteurs d’InhA de Mycobacterium tuberculosis