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Could a Feeding Jejunostomy be Integrated into a Standardized Preoperative Management of Oeso-gastric Junction Adenocarcinoma?

 Simone Manfredelli , Jean-Baptiste Delhorme , Aina Venkatasamy , Christian Gaiddon , Cécile Brigand , et al.
Annals of Surgical Oncology, 2017, 24 (11), pp.3324-3330. ⟨10.1245/s10434-017-5945-9⟩
Article dans une revue inserm-02364176v1

Light activation of cyclometalated ruthenium complexes drives towards caspase 3 dependent apoptosis in gastric cancer cells

 Jorge Andrés Solís-Ruiz , Anaïs Barthe , Gilles Riegel , Rafael Omar Saavedra-Díaz , Christian Gaiddon , et al.
Journal of Inorganic Biochemistry, 2020, 208, pp.111080. ⟨10.1016/j.jinorgbio.2020.111080⟩
Article dans une revue hal-03044543v1
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Rollover Cyclometalated Bipyridine Platinum Complexes as Potent Anticancer Agents: Impact of the Ancillary Ligands on the Mode of Action

 Maria Babak , Martin Pfaffeneder-Kmen , Samuel Meier-Menches , Maria Legina , Sarah Theiner , et al.
Inorganic Chemistry, 2018, 57 (5), pp.2851-2864. ⟨10.1021/acs.inorgchem.7b03210⟩
Article dans une revue inserm-02364163v1

Monomeric Ti( iv )-based complexes incorporating luminescent nitrogen ligands: synthesis, structural characterization, emission spectroscopy and cytotoxic activities

 Georges Khalil , Christophe Orvain , Lu Fang , Laurent Barloy , Alain Chaumont , et al.
Dalton Transactions, 2016, 45 (47), pp.19072-19085. ⟨10.1039/c6dt03477b⟩
Article dans une revue hal-02353930v1
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A Subset of Tumor-Derived Mutant Forms of p53 Down-Regulate p63 and p73 through a Direct Interaction with the p53 Core Domain

 C. Gaiddon , M. Lokshin , J. Ahn , Tiantian Zhang , C. Prives
Molecular and Cellular Biology, 2001, 21 (5), pp.1874-1887. ⟨10.1128/MCB.21.5.1874-1887.2001⟩
Article dans une revue inserm-02360323v1
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HDAC4 Levels Control Sensibility toward Cisplatin in Gastric Cancer via the p53-p73/BIK Pathway

 Marie-Elodie Spaety , Alexandre Gries , Amandine Badie , Aina Venkatasamy , Benoît Romain , et al.
Cancers, 2019, 11 (11), pp.1747. ⟨10.3390/cancers11111747⟩
Article dans une revue inserm-02363213v1
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Morpho-functional analysis of patient-derived xenografts reveals differential impact of gastric cancer and chemotherapy on the tumor ecosystem, affecting immune check point, metabolism, and sarcopenia

 A. Venkatasamy , E. Guerin , W. Reichardt , V. Devignot , M P Chenard , et al.
Gastric Cancer, 2022, 26 (2), pp.220-233. ⟨10.1007/s10120-022-01359-w⟩
Article dans une revue hal-04295287v1

How to Prevent Sarcopenia Occurrence during Neoadjuvant Chemotherapy for Oesogastric Adenocarcinoma?

 Marlène Voisinet , Aïna Venkatasamy , Hefzi Alratrout , Jean-Baptiste Delhorme , Cécile Brigand , et al.
Nutrition and Cancer, 2020, pp.1-7. ⟨10.1080/01635581.2020.1770813⟩
Article dans une revue hal-03044558v1
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Discovery and Investigation of Anticancer Ruthenium–Arene Schiff-Base Complexes via Water-Promoted Combinatorial Three-Component Assembly

 Mun Juinn Chow , Cynthia Licona , Daniel Yuan Qiang Wong , Giorgia Pastorin , Christian Gaiddon , et al.
Journal of Medicinal Chemistry, 2014, 57 (14), pp.6043-6059. ⟨10.1021/jm500455p⟩
Article dans une revue inserm-02360394v1
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A novel ΔNp63-dependent immune mechanism improves prognosis of HPV-related head and neck cancer

 Jana Mourtada , Christelle Lony , Anaïs Nicol , Justine de Azevedo , Cyril Bour , et al.
Frontiers in Immunology, 2023, 14, pp.1264093. ⟨10.3389/fimmu.2023.1264093⟩
Article dans une revue hal-04440322v1
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Bifunctional ligand design for modulating mutant p53 aggregation in cancer

 Jessica Miller , Anaïs Blanchet , Christophe Orvain , Lucienne Nouchikian , Yasmin Reviriot , et al.
Chemical Science, 2019, Epub ahead of print. ⟨10.1039/c9sc04151f⟩
Article dans une revue inserm-02364138v1
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A role for bioinorganic chemistry in the reactivation of mutant p53 in cancer

 Jessica J. Miller , Kalvin Kwan , Christian Gaiddon , Tim Storr
Journal of Biological Inorganic Chemistry, 2022, 27 (4-5), pp.393-403. ⟨10.1007/s00775-022-01939-2⟩
Article dans une revue hal-03803849v1
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Multifunctional metallochaperone modifications for targeting subsite cavities in mutant p53-Y220C

 Jessica J Miller , Kalvin Kwan , Anaïs Blanchet , Christophe Orvain , Georg Mellitzer , et al.
Journal of Inorganic Biochemistry, 2023, 242, pp.112164. ⟨10.1016/j.jinorgbio.2023.112164⟩
Article dans une revue hal-04295261v1
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Holographic Traction Force Microscopy

 Stanislaw Makarchuk , Nicolas Beyer , Christian Gaiddon , Wilfried Grange , Pascal Hebraud
Scientific Reports, 2018, 8 (1), pp.3038. ⟨10.1038/s41598-018-21206-2⟩
Article dans une revue inserm-02364168v1

Novel Flavaglines Displaying Improved Cytotoxicity.

 Frédéric Thuaud , Nigel Ribeiro , Christian Gaiddon , Thierry Cresteil , Laurent Désaubry
Journal of Medicinal Chemistry, 2010, 54 (1), pp.411-415. ⟨10.1021/jm101318b⟩
Article dans une revue hal-00572526v1

Reactivity of Cu( ii )–, Zn( ii )– and Fe( ii )–thiosemicarbazone complexes with glutathione and metallothionein: from stability to dissociation to transmetallation

 Alice Santoro , Bertrand Vileno , Oscar Palacios , Manuel David Peris-Díaz , Gilles Riegel , et al.
Metallomics, 2019, 11 (5), pp.994-1004. ⟨10.1039/C9MT00061E⟩
Article dans une revue hal-02339840v1
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A Ruthenium-Containing Organometallic Compound Reduces Tumor Growth through Induction of the Endoplasmic Reticulum Stress Gene CHOP

 Xiangjun Meng , Mili Leyva , Marjorie Jenny , Isabelle Gross , Samir Benosman , et al.
Cancer Research, 2009, 69 (13), pp.5458-5466. ⟨10.1158/0008-5472.CAN-08-4408⟩
Article dans une revue inserm-02360367v1
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Structural Determinants of p53-Independence in Anticancer Ruthenium-Arene Schiff-Base Complexes

 Mun Juinn Chow , Maria Babak , Daniel Yuan Qiang Wong , Giorgia Pastorin , Christian Gaiddon , et al.
Molecular Pharmaceutics, 2016, 13 (7), pp.2543-2554. ⟨10.1021/acs.molpharmaceut.6b00348⟩
Article dans une revue inserm-02365323v1
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Alteration of the Bcl-x/Bax Ratio in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis: Evidence for the Implication of the p53 Signaling Pathway

 Jose-Luis Gonzalez de Aguilar , Jon Gordon , Frédérique Rene , Marc de Tapia , Bernadette Lutz-Bucher , et al.
Neurobiology of Disease, 2000, 7 (4), pp.406-415. ⟨10.1006/nbdi.2000.0295⟩
Article dans une revue istex inserm-02360380v1
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Brain-Derived Neurotrophic Factor Stimulates AP-1 and Cyclic AMP-Responsive Element Dependent Transcriptional Activity in Central Nervous System Neurons

 C. Gaiddon , J. Loeffler , Y. Larmet
Journal of Neurochemistry, 1996, 66 (6), pp.2279-2286. ⟨10.1046/j.1471-4159.1996.66062279.x⟩
Article dans une revue inserm-02360385v1
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Transcriptional activator TAp63 is upregulated in muscular atrophy during ALS and induces the pro-atrophic ubiquitin ligase Trim63

 Yannick von Grabowiecki , Paula Abreu , Orphee Blanchard , Lavinia Palamiuc , Samir Benosman , et al.
eLife, 2016, 5, pp.e10528. ⟨10.7554/eLife.10528⟩
Article dans une revue inserm-02365332v1
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Current Clinical and Pre-Clinical Imaging Approaches to Study the Cancer-Associated Immune System

 Christopher Mueller , Christian Gaiddon , Aïna Venkatasamy
Frontiers in Immunology, 2021, 12, pp.716860. ⟨10.3389/fimmu.2021.716860⟩
Article dans une revue hal-03450756v1

Flavaglines as potent anticancer and cytoprotective agents.

 Nigel Ribeiro , Frédéric Thuaud , Yohann Bernard , Christian Gaiddon , Thierry Cresteil , et al.
Journal of Medicinal Chemistry, 2012, 55 (22), pp.10064-73. ⟨10.1021/jm301201z⟩
Article dans une revue hal-00765387v1
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Dichloroacetate restores colorectal cancer chemosensitivity through the p53/miR-149-3p/PDK2-mediated glucose metabolic pathway

 Yu Liang , Lidan Hou , Linjing Li , Lei Li , Liming Zhu , et al.
Oncogene, 2019, Epub ahead of print]. ⟨10.1038/s41388-019-1035-8⟩
Article dans une revue inserm-02364194v1
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The Fate of Cycloruthenated Compounds: From C-H Activation to Innovative Anticancer Therapy

 Christian Gaiddon , Michel Pfeffer
European Journal of Inorganic Chemistry, 2017, 2017 (12), pp.1639-1654. ⟨10.1002/ejic.201601216⟩
Article dans une revue inserm-02365284v1
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Constitutive or Induced HIF-2 Addiction is Involved in Resistance to Anti-EGFR Treatment and Radiation Therapy in HNSCC

 Pierre Coliat , Ludivine Ramolu , Jérémie Jégu , Christian Gaiddon , Alain Jung , et al.
Cancers, 2019, 11 (10), pp.1607. ⟨10.3390/cancers11101607⟩
Article dans une revue inserm-02364190v1
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Immune cell-derived beta-endorphin. Production, release, and control of inflammatory pain in rats.

 P Cabot , L Carter , C Gaiddon , Q. Zhang , M. Schafer , et al.
Journal of Clinical Investigation, 1997, 100 (1), pp.142-148. ⟨10.1172/JCI119506⟩
Article dans une revue inserm-02360337v1
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Ref-1 regulates the transactivation and pro-apoptotic functions of p53 in vivo

 Christian Gaiddon , N.C. Moorthy , Carol Prives
EMBO Journal, 1999, 18 (20), pp.5609-5621. ⟨10.1093/emboj/18.20.5609⟩
Article dans une revue inserm-02360357v1

Bypassing the Resistance Mechanisms of the Tumor Ecosystem by Targeting the Endoplasmic Reticulum Stress Pathway Using Ruthenium- and Osmium-Based Organometallic Compounds: An Exciting Long-Term Collaboration with Dr. Michel Pfeffer

 Christian Gaiddon , Isabelle Gross , Xiangjun Meng , Marjorie Sidhoum , Georg Mellitzer , et al.
Molecules, 2021, 26 (17), pp.5386. ⟨10.3390/molecules26175386⟩
Article dans une revue hal-03450715v1
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Apoptosis-independent organoruthenium anticancer complexes that overcome multidrug resistance: self-assembly and phenotypic screening strategies

 Mun Juinn Chow , Mohammad Alfiean , Giorgia Pastorin , Christian Gaiddon , Wee Han Ang
Chemical Science, 2017, 8 (5), pp.3641-3649. ⟨10.1039/c7sc00497d⟩
Article dans une revue inserm-02365265v1
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