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In vivo imaging of MmpL transporters reveals distinct subcellular locations for export of mycolic acids and non-essential trehalose polyphleates in the mycobacterial outer membrane

 Laurie Thouvenel , Jérôme Rech , Christophe Guilhot , Jean-Yves Bouet , Christian Chalut
Scientific Reports, 2023, 13 (1), pp.7045. ⟨10.1038/s41598-023-34315-4⟩
Article dans une revue hal-04119944v1

Biosynthesis and Roles of Phenolic Glycolipids and Related Molecules in Mycobacterium tuberculosis

 Christophe Guilhot , Christian Chalut , Mamadou Daffé
The Mycobacterial Cell Envelope, ASM Press, pp.271-289, 2014, ⟨10.1128/9781555815783.ch17⟩
Chapitre d'ouvrage hal-03199103v1

Expression in Escherichia coli: Production and Purification of Both Subunits of the Human General Transcription Factor TFIIE

 C. Chalut , Cathy Lang , Jean-Marc Egly
Protein Expression and Purification, 1994, 5 (5), pp.458-467. ⟨10.1006/prep.1994.1065⟩
Article dans une revue istex hal-03184520v1

Molecular dissection of the biosynthetic relationship between phthiocerol and phthiodiolone dimycocerosates and their critical role in the virulence and permeability of Mycobacterium tuberculosis

 Roxane Simeone , Patricia Constant , Wladimir Malaga , Christophe Guilhot , Mamadou Daffé , et al.
FEBS Journal, 2007, 274 (8), pp.1957-1969. ⟨10.1111/j.1742-4658.2007.05740.x⟩
Article dans une revue pasteur-02862986v1
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Phthiocerol Dimycocerosates From Mycobacterium tuberculosis Increase the Membrane Activity of Bacterial Effectors and Host Receptors

 Jacques Augenstreich , Evert Haanappel , Fadel Sayes , Roxane Simeone , Valerie Guillet , et al.
Frontiers in Cellular and Infection Microbiology, 2020, 10, pp.420. ⟨10.3389/fcimb.2020.00420⟩
Article dans une revue pasteur-02873531v1
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The Polyketide Synthase Pks13 Catalyzes a Novel Mechanism of Lipid Transfer in Mycobacteria

 Sabine Gavalda , Fabienne Bardou , Françoise Laval , Cécile Bon , Wladimir Malaga , et al.
Chemistry and Biology, 2014, 21 (12), pp.1660 - 1669. ⟨10.1016/j.chembiol.2014.10.011⟩
Article dans une revue hal-03002982v1
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The final assembly of trehalose polyphleates takes place within the outer layer of the mycobacterial cell envelope

 Laurie Thouvenel , Gautier Prevot , Laura Chiaradia , Julien Parra , Emmanuelle Mouton-Barbosa , et al.
Journal of Biological Chemistry, 2020, 295 (32), pp.11184-11194. ⟨10.1074/jbc.RA120.013299⟩
Article dans une revue hal-02994941v1

Identification of the Missing trans-Acting Enoyl Reductase Required for Phthiocerol Dimycocerosate and Phenolglycolipid Biosynthesis in Mycobacterium tuberculosis

 Roxane Simeone , Patricia Constant , Christophe Guilhot , Mamadou Daffé , Christian Chalut
Journal of Bacteriology, 2007, 189 (13), pp.4597-4602. ⟨10.1128/JB.00169-07⟩
Article dans une revue pasteur-02862990v1
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4′-Phosphopantetheinyl Transferase PptT, a New Drug Target Required for Mycobacterium tuberculosis Growth and Persistence In Vivo

 Cécile Leblanc , Thomas Prudhomme , Guillaume Tabouret , Aurélie Ray , Sophie Burbaud , et al.
PLoS Pathogens, 2012, 8 (12), pp.e1003097. ⟨10.1371/journal.ppat.1003097⟩
Article dans une revue hal-02391857v1

Cloning of the 62-kilodalton component of basic transcription factor BTF2

 L Fischer , M Gerard , C Chalut , Y Lutz , S Humbert , et al.
Science, 1992, 257 (5075), pp.1392-1395. ⟨10.1126/science.1529339⟩
Article dans une revue hal-03184523v1

Genomic structure of the putative BTF3 transcription factor

 Masamoto Kanno , Christian Chalut , Jean-Marc Egly
Gene, 1992, 117 (2), pp.219-228. ⟨10.1016/0378-1119(92)90732-5⟩
Article dans une revue istex hal-03184531v1
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Druggable redox pathways against Mycobacterium abscessus in cystic fibrosis patient-derived airway organoids

 Stephen Adonai Leon-Icaza , Salimata Bagayoko , Romain Vergé , Nino Iakobachvili , Chloé Ferrand , et al.
PLoS Pathogens, 2023, 19 (8), pp.e1011559. ⟨10.1371/journal.ppat.1011559⟩
Article dans une revue hal-04197558v1
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Mycobacteria–host interactions in human bronchiolar airway organoids

 Nino Iakobachvili , Stephen Adonai Leon‐icaza , Kèvin Knoops , Norman Sachs , Serge Mazères , et al.
Molecular Microbiology, 2022, 117 (3), pp.682-692. ⟨10.1111/mmi.14824⟩
Article dans une revue hal-03856942v1
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Phthiocerol Dimycocerosates of M. tuberculosis Participate in Macrophage Invasion by Inducing Changes in the Organization of Plasma Membrane Lipids

 Catherine Astarie-Dequeker , Laurent Le Guyader , Wladimir Malaga , Fam-Ky Seaphanh , Christian Chalut , et al.
PLoS Pathogens, 2009, 5 (2), pp.e1000289. ⟨10.1371/journal.ppat.1000289⟩
Article dans une revue hal-02333313v1

The nonredundant roles of two 4'-phosphopantetheinyl transferases in vital processes of Mycobacteria

 C. Chalut , L. Botella , C. de Sousa-d'Auria , C. Houssin , C. Guilhot
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (22), pp.8511-8516. ⟨10.1073/pnas.0511129103⟩
Article dans une revue hal-03003055v1

MmpL transporter-mediated export of cell-wall associated lipids and siderophores in mycobacteria

 Christian Chalut
Tuberculosis, 2016, 100, pp.32-45. ⟨10.1016/j.tube.2016.06.004⟩
Article dans une revue hal-02391838v1

Expression inEscherichia coli: Purification and properties of the recombinant human general transcription factor rTFII B

 Vincent Moncollin , Laurent Schaeffer , Christian Chalut , Jean-Marc Egly
Protein Expression and Purification, 1992, 3 (5), pp.374-379. ⟨10.1016/s1046-5928(05)80038-5⟩
Article dans une revue istex hal-03184528v1

AUC is used as a start codon in Escherichia coli

 Christian Chalut , Jean-Marc Egly
Gene, 1995, 156 (1), pp.43-45. ⟨10.1016/0378-1119(95)00034-4⟩
Article dans une revue istex hal-03184516v1
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Interplay between Siderophores and Colibactin Genotoxin Biosynthetic Pathways in Escherichia coli

 Patricia Martin , Ingrid Marcq , Giuseppe Magistro , Marie Penary , Christophe Garcie , et al.
PLoS Pathogens, 2013, 9 (7), pp.e1003437. ⟨10.1371/journal.ppat.1003437⟩
Article dans une revue hal-02391854v1

Genomic structure of the human TATA-box-binding protein (TBP)

 Christian Chalut , Yves Gallois , Arnaud Poterszman , Vincent Moncollin , Jean-Marc Egly
Gene, 1995, 161 (2), pp.277-282. ⟨10.1016/0378-1119(95)00209-o⟩
Article dans une revue istex hal-03184513v1

Disulfide Bridges Are Not Involved in Penicillin-Binding Protein 1b Dimerization in Escherichia coli

 Christian Chalut , Marie-Hélène Remy , Jean-Michel Masson
Journal of Bacteriology, 1999, 181 (9), pp.2970-2972. ⟨10.1128/JB.181.9.2970-2972.1999⟩
Article dans une revue hal-03003071v1
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Biochemical and Structural Study of the Atypical Acyltransferase Domain from the Mycobacterial Polyketide Synthase Pks13

 Fabien Bergeret , Sabine Gavalda , Christian Chalut , Wladimir Malaga , Annaïk Quémard , et al.
Journal of Biological Chemistry, 2012, 287, pp.33675 - 33690. ⟨10.1074/jbc.m111.325639⟩
Article dans une revue hal-03003064v1
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Detection of soluble co-factor dependent protein expression in vivo : Application to the 4′-phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis

 Karine Rottier , Alexandre Faille , Thomas Prudhomme , Cécile Leblanc , Christian Chalut , et al.
Journal of Structural Biology, 2013, 183 (3), pp.320 - 328. ⟨10.1016/j.jsb.2013.07.010⟩
Article dans une revue hal-03002994v1

A Role for ATP and TFIIH in Activation of the RNA Polymerase II Preinitiation Complex Prior to Transcription Initiation

 Arik Dvir , Karla Pfeil Garrett , Christian Chalut , Jean-Marc Egly , Joan Weliky Conaway , et al.
Journal of Biological Chemistry, 1996, 271 (13), pp.7245-7248. ⟨10.1074/jbc.271.13.7245⟩
Article dans une revue hal-03184504v1
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Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases

 Anna D Grabowska , Yoann Brison , Laurent Maveyraud , Sabine Gavalda , Alexandre Faille , et al.
ACS Chemical Biology, 2020, 15 (12), pp.3206 - 3216. ⟨10.1021/acschembio.0c00772⟩
Article dans une revue hal-03752170v2
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Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds

 Coralie Carivenc , Laurent Maveyraud , Claire Blanger , Stéphanie Ballereau , Coralie Roy-Camille , et al.
Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-97197-4⟩
Article dans une revue hal-03345048v1

Trehalose Polyphleates Are Produced by a Glycolipid Biosynthetic Pathway Conserved across Phylogenetically Distant Mycobacteria

 Sophie Burbaud , Françoise Laval , Anne Lemassu , Mamadou Daffé , Christophe Guilhot , et al.
Cell Chemical Biology, 2016, 23 (2), pp.278-289. ⟨10.1016/j.chembiol.2015.11.013⟩
Article dans une revue hal-02322348v1

Solution structure of the type I polyketide synthase Pks13 from Mycobacterium tuberculosis

 Bon Cécile , Cabantous Stéphanie , Julien Sylviane , Guillet Valérie , Chalut Christian , et al.
EMBO Workshop on Tuberculosis 2022, Sep 2022, Paris, France
Communication dans un congrès hal-03820163v1

ESX-1 and phthiocerol dimycocerosates of Mycobacterium tuberculosis act in concert to cause phagosomal rupture and host cell apoptosis

 Jacques Augenstreich , Ainhoa Arbues , Roxane Simeone , Evert Haanappel , Alice Wegener , et al.
Cellular Microbiology, 2017, 19 (7), pp.e12726. ⟨10.1111/cmi.12726⟩
Article dans une revue hal-02326055v1

Delineation of the roles of FadD22, FadD26 and FadD29 in the biosynthesis of phthiocerol dimycocerosates and related compounds in Mycobacterium tuberculosis

 Roxane Simeone , Mathieu Léger , Patricia Constant , Wladimir Malaga , Hedia Marrakchi , et al.
FEBS Journal, 2010, 277 (12), pp.2715-2725. ⟨10.1111/j.1742-464X.2010.07688.x⟩
Article dans une revue pasteur-02862996v1
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