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Chantal Pichon

197
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Publications

Reversible stabilization of DNA/PEI complexes by reducible click-linkage between DNA and polymer. A new polyplex concept for lowering polymer quantity

Delphine Maze , Chantal Pichon , Patrick Midoux
Gene Therapy, inPress, ⟨10.1038/s41434-023-00386-1⟩
Article dans une revue hal-04215541v1

Selective attachment of a microtubule interacting peptide to plasmid DNA via a triplex forming oligonucleotide for transfection improvement

Caroline Girardin , Delphine Maze , Cristine Gonçalves , Yann Thierry Le Guen , Kevin Pluchon
Gene Therapy, 2023, 30 (3-4), pp.271-277. ⟨10.1038/s41434-022-00354-1⟩
Article dans une revue hal-04169701v1
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Targeting TGF-β1/miR-21 Pathway in Keratinocytes Reveals Protective Effects of Silymarin on Imiquimod-Induced Psoriasis Mouse Model

Elodie Henriet , Florence Abdallah , Yoan Laurent , Cyril Guimpied , Emily Clement
JID Innovations, 2023, 3 (3), pp.100175. ⟨10.1016/j.xjidi.2022.100175⟩
Article dans une revue hal-04220607v1

Murine Breast Cancer Radiosensitization Using Oxygen Microbubbles and Metformin: Vessels Are the Key

Agnieszka Drzał , Gabriela Dziurman , Paweł Hoła , Jakub Lechowski , Anthony Delalande
International Journal of Molecular Sciences, 2023, 24 (15), pp.12156. ⟨10.3390/ijms241512156⟩
Article dans une revue hal-04185608v1

Intrahippocampal Inoculation of Aβ1–42 Peptide in Rat as a Model of Alzheimer’s Disease Identified MicroRNA-146a-5p as Blood Marker with Anti-Inflammatory Function in Astrocyte Cells

Ruth Aquino , Vidian de Concini , Marc Dhenain , Suzanne Lam , David Gosset
Cells, 2023, 12 (5), pp.694. ⟨10.3390/cells12050694⟩
Article dans une revue hal-04215705v1
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Maternal-Fetal Implications of SARS CoV-2 Infection during Pregnancy, Viral, Serological Analyses of Placenta and Cord Blood

Souhail Alouini , Jerôme Guinard , Olivier Belin , Louis Mesnard , Evelyne Werner
International Journal of Environmental Research and Public Health, 2022, 19 (4), pp.2105. ⟨10.3390/ijerph19042105⟩
Article dans une revue hal-03927230v1
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mRNA Lipoplexes with Cationic and Ionizable α-Amino-lipophosphonates: Membrane Fusion, Transfection, mRNA Translation and Conformation

Sohail Akhter , Mathieu Berchel , Paul-Alain Jaffrès , Chantal Pichon , Patrick Midoux
Pharmaceutics, 2022, 14 (3), pp.581. ⟨10.3390/pharmaceutics14030581⟩
Article dans une revue hal-03927316v1
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Impact of Treadmill Interval Running on the Appearance of Zinc Finger Protein FHL2 in Bone Marrow Cells in a Rat Model: A Pilot Study

Alexandre Germain , Celine Bourzac , Chantal Pichon , Hugues Portier , Stéphane Pallu
Life, 2022, 12 (4), pp.528. ⟨10.3390/life12040528⟩
Article dans une revue hal-03881072v1
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Doxorubicin‐sensitized Luminescence of NIR‐emitting Ytterbium Liposomes: Towards Direct Monitoring of Drug Release

S. Lacerda , Anthony Delalande , Svetlana V. Eliseeva , Agnes A. Pallier , Celia ́ Bonnet
Angewandte Chemie International Edition, 2021, 60 (44), pp.23574-23577. ⟨10.1002/anie.202109408⟩
Article dans une revue hal-03349106v1
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The role of mergers and interactions in driving the evolution of dwarf galaxies over cosmic time

G Martin , R Jackson , S Kaviraj , H Choi , J Devriendt
Monthly Notices of the Royal Astronomical Society, 2021, 500 (4), pp.4937-4957. ⟨10.1093/mnras/staa3443⟩
Article dans une revue hal-03102202v1
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In Vivo Bone Tissue Induction by Freeze-dried Collagen-nanohydroxyapatite Matrix Loaded with BMP2/NS1 mRNAs Lipopolyplexes

Pinpin Wang , Federico Perche , Patrick Midoux , Catia S.D. Cabral , Virginie Malard
Journal of Controlled Release, 2021, 334, pp.188-200. ⟨10.1016/j.jconrel.2021.04.021⟩
Article dans une revue hal-03209056v1
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miRNA Delivery by Nanosystems: State of the Art and Perspectives

Fernanda Moraes , Chantal Pichon , Didier Letourneur , Frédéric Chaubet
Pharmaceutics, 2021, 13 (11), pp.1901. ⟨10.3390/pharmaceutics13111901⟩
Article dans une revue hal-03470645v1

Flow cytometry assay to evaluate lipid production by the marine microalga Tetraselmis sp. using a two stage process

Mouna Dammak , Hajer Ben Hlima , Fatma Elleuch , Chantal Pichon , Philippe Michaud
Renewable Energy, 2021, 177, pp.280-289. ⟨10.1016/j.renene.2021.05.126⟩
Article dans une revue hal-03335692v1
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LentiRILES, a miRNA-ON Sensor System for Monitoring the Functionality of miRNA in Cancer Biology and Therapy

Viorel Simion , Claire Loussouarn , Yoan Laurent , Loris Roncali , David Gosset
RNA Biology/RNA Biol., 2021, Online ahead of print. ⟨10.1080/15476286.2021.1978202⟩
Article dans une revue inserm-03374619v1
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miR-21-3p/IL-22 axes are major drivers of psoriasis pathogenesis by modulating keratinocytes proliferationsurvival balance and inflammatory response

Florence Abdallah , Elodie Henriet , Amandine Suet , Ali Arar , Rudy Clemençon
Cells, 2021, 10 (10), pp.2547. ⟨10.3390/cells10102547⟩
Article dans une revue hal-03434971v1
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Intracellular Routing and Recognition of Lipid-Based mRNA Nanoparticles

Christophe Delehedde , Luc Even , Patrick Midoux , Chantal Pichon , Federico Perche
Pharmaceutics, 2021, 13 (7), pp.945. ⟨10.3390/pharmaceutics13070945⟩
Article dans une revue hal-03335664v1
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Design and delivery of messenger RNA-based vaccines

Chantal Pichon , Federico Perche
The Biochemist, 2021, 43 (4), ⟨10.1042/bio_2021_151⟩
Article dans une revue hal-03364925v1

mRNA, a Revolution in Biomedicine

Bruno Baptista , Rita Carapito , Nabila Laroui , Chantal Pichon , Fani Sousa
Pharmaceutics, 2021, 13 (12), pp.2090. ⟨10.3390/pharmaceutics13122090⟩
Article dans une revue hal-03927095v1
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Periodic Mesoporous Organosilica Nanoparticles with BOC Group, towards HIFU Responsive Agents

Hao Li , Carolina Gascó , Anthony Delalande , Clarence Charnay , Laurence Raehm
Molecules, 2020, 25 (4), pp.974. ⟨10.3390/molecules25040974⟩
Article dans une revue hal-02544155v1
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PhotoWeb redshift: boosting photometric redshift accuracy with large spectroscopic surveys

M. Shuntov , J. Pasquet , S. Arnouts , O. Ilbert , M. Treyer
Astronomy and Astrophysics - A&A, 2020, 636, pp.A90. ⟨10.1051/0004-6361/201937382⟩
Article dans une revue hal-03049082v1
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Comparative binding and uptake of liposomes decorated with mannose oligosaccharides by cells expressing the mannose receptor or DC-SIGN

Haifei Gao , Cristine Goncalves , Téo Gallego , Marc Francois-Heude , Virginie Malard
Carbohydrate Research, 2020, 487, pp.107877. ⟨10.1016/j.carres.2019.107877⟩
Article dans une revue hal-02522179v1
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Deciphering the Biological Activities of Dunaliella sp. Aqueous Extract from Stressed Conditions on Breast Cancer: from in Vitro to in Vivo Investigations

Fatma Elleuch , Patrick Baril , Mohamed Barkallah , Federico Perche , Slim Abdelkafi
International Journal of Molecular Sciences, 2020, 21 (5), pp.1719. ⟨10.3390/ijms21051719⟩
Article dans une revue hal-02553031v1

Draft Genome Sequence of Lactobacillus crispatus CIP 104459, Isolated from a Vaginal Swab

Maximilien Clabaut , Amine Boukerb , Pierre-Jean Racine , Chantal Pichon , Coralie Kremser
Microbiology Resource Announcements, 2020, 9 (2), ⟨10.1128/MRA.01373-19⟩
Article dans une revue hal-02535839v1
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New insights on molecular internalization and drug delivery following plasma jet exposures

Vinodini Vijayarangan , Antony Delalande , Sébastien Dozias , Jean-Michel Pouvesle , Eric Robert
International Journal of Pharmaceutics, 2020, 589, pp.119874. ⟨10.1016/j.ijpharm.2020.119874⟩
Article dans une revue hal-03043274v1
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Protective Role of Spirulina platensis against Bifenthrin-Induced Reprotoxicity in Adult Male Mice by Reversing Expression of Altered Histological, Biochemical, and Molecular Markers Including MicroRNAs

Mohamed Barkallah , Ahlem Ben Slima , Fatma Elleuch , Imen Fendri , Chantal Pichon
Biomolecules, 2020, 10 (5), pp.753. ⟨10.3390/biom10050753⟩
Article dans une revue hal-02901693v1
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Intracellular trafficking and functional monitoring of miRNA delivery in glioblastoma using lipopolyplexes and the miRNA-ON RILES reporter system

Viorel Simion , Elodie Henriet , Viktorija Juric , Ruth Aquino , Claire Loussouarn
Journal of Controlled Release, 2020, 327, pp.429-443. ⟨10.1016/j.jconrel.2020.08.028⟩
Article dans une revue hal-02959393v1
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Potential of Exopolysaccharide from Porphyridium marinum to Contend with Bacterial Proliferation, Biofilm Formation, and Breast Cancer

Nesrine Gargouch , Fatma Elleuch , Ines Karkouch , Olfa Tabbene , Chantal Pichon
Marine drugs, 2020, 19 (2), pp.66. ⟨10.3390/md19020066⟩
Article dans une revue hal-03462962v1
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mRNA with Mammalian Codon Bias Accumulates in Yeast Mutants with Constitutive Stress Granules

Natalia Kozlova , Chantal Pichon , A. Rachid Rahmouni
International Journal of Molecular Sciences, 2020, 21 (4), pp.1234. ⟨10.3390/ijms21041234⟩
Article dans une revue hal-02524994v1
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Nanomedicine-Based Approaches for mRNA Delivery

Satoshi Uchida , Federico Perche , Chantal Pichon , Horacio Cabral
Molecular Pharmaceutics, 2020, 17 (10), pp.3654 - 3684. ⟨10.1021/acs.molpharmaceut.0c00618⟩
Article dans une revue hal-02995814v1
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Co-delivery of NS1 and BMP2 mRNAs to murine pluripotent stem cells leads to enhanced BMP-2 expression and osteogenic differentiation

Pinpin Wang , Delphine Logeart-Avramoglou , Hervé Petite , Cristine Gonçalves , Patrick Midoux
Acta Biomaterialia, 2020, 108, pp.337-346. ⟨10.1016/j.actbio.2020.03.045⟩
Article dans une revue hal-02553030v1
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Neutral Lipopolyplexes for In Vivo Delivery of Conventional and Replicative RNA Vaccine

Federico Perche , Rudy Clemençon , Kai Schulze , Thomas Ebensen , Carlos Guzman
Molecular Therapy - Nucleic Acids, 2019, 17, pp.767-775. ⟨10.1016/j.omtn.2019.07.014⟩
Article dans une revue hal-02321815v1
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Quantitative determination of Andrographolide and related compounds in Andrographis paniculata extracts and biological evaluation of their anti-inflammatory activity

Emmanuelle Villedieu Villedieu-Percheron , Véronique Ferreira , Joana Filomena Campos , Emilie Destandau , Chantal Pichon
Foods, 2019, 8 (12), pp.683. ⟨10.3390/foods8120683⟩
Article dans une revue hal-02521988v1
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Amino-acid functionalized porous silicon nanoparticles for the delivery of pDNA

Arnaud Chaix , Eduardo Cueto-Diaz , Anthony Delalande , Nikola Knezevic , Patrick Midoux
RSC Advances, 2019, 9 (55), pp.31895-31899. ⟨10.1039/c9ra05461h⟩
Article dans une revue hal-02338857v1

Draft Genome Sequence of Lactobacillus crispatus Strain V4, Isolated from a Vaginal Swab from a Young Healthy Nonmenopausal Woman

Maximilien Clabaut , Amine Boukerb , Pierre-Jean Racine , Chantal Pichon , Coralie Kremser
Microbiology Resource Announcements, 2019, 8 (38), pp.e00856-19. ⟨10.1128/MRA.00856-19⟩
Article dans une revue hal-02309567v1
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Cardiolipin-Based Lipopolyplex Platform for the Delivery of Diverse Nucleic Acids into Gram-Negative Bacteria

Federico Perche , Tony Le Gall , Tristan Montier , Chantal Pichon , Jean-Marc Malinge
Pharmaceuticals, 2019, 12 (2), pp.81. ⟨10.3390/ph12020081⟩
Article dans une revue hal-02172973v1
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Evidence on the direct correlation between miR‐31 and IL‐22 axis in IMQ‐induced psoriasis

Florence Abdallah , Chantal Pichon
Experimental Dermatology, 2019, 28 (11), pp.1336-1340. ⟨10.1111/exd.14001⟩
Article dans une revue hal-02521769v1
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RNA-based therapy for osteogenesis

Pinpin Wang , Federico Perche , Delphine Logeart-Avramoglou , Chantal Pichon
International Journal of Pharmaceutics, 2019, 569, pp.118594. ⟨10.1016/j.ijpharm.2019.118594⟩
Article dans une revue hal-02995602v1
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Improved histidinylated lPEI polyplexes for skeletal muscle cells transfection

Jean-Pierre Gomez , Guillaume Tresset , Chantal Pichon , Patrick Midoux
International Journal of Pharmaceutics, 2019, 559, pp.58-67. ⟨10.1016/j.ijpharm.2019.01.003⟩
Article dans une revue hal-02067297v1
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R. nukuhivensis acts by reinforcing skin barrier function, boosting skin immunity and by inhibiting IL-22 induced keratinocyte hyperproliferation

Florence Abdallah , Gaêl Lecellier , Phila Raharivelomanana , Chantal Pichon
Scientific Reports, 2019, 9 (4132), ⟨10.1038/s41598-019-39831-w⟩
Article dans une revue hal-02521734v1
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Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety

Kevin van Der Jeught , Stefaan de Koker , Lukasz Bialkowski , Carlo Heirman , Patrick Tjok Joe
ACS Nano, 2018, 12 (10), pp.9815-9829. ⟨10.1021/acsnano.8b00966⟩
Article dans une revue hal-01889829v1
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Modelling Tetraselmis sp. growth-kinetics and optimizing bioactive-compound production through environmental conditions

Mouna Dammak , Bilel Hadrich , Mohamed Barkallah , Faiez Hentati , Hajer Ben Hlima
Bioresource Technology, 2018, 249, pp.510-518. ⟨10.1016/j.biortech.2017.10.028⟩
Article dans une revue hal-02520703v1
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Tamanu oil and skin active properties: from traditional to modern cosmetic uses

Phila Raharivelomanana , Jean-Luc Ansel , Elise Lupo , Lily Mijouin , Samuel Guillot
Oléagineux, Corps Gras, Lipides, 2018, 5 (5), pp.D504
Article dans une revue hal-01966367v1
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Novel Perfluorinated Triblock Amphiphilic Copolymers for Lipid-Shelled Microbubble Stabilization

Yohann Corvis , Simona Manta , Caroline Thébault , Olivier Couture , Hélène Dhotel
Langmuir, 2018, 34 (33), pp.9744-9753. ⟨10.1021/acs.langmuir.8b01668⟩
Article dans une revue hal-02123140v1

Preclinical evaluation of mRNA trimannosylated lipopolyplexes as therapeutic cancer vaccines targeting dendritic cells

A. Le Moignic , V. Malard , T. Benvegnu , L. Lemiègre , Mathieu Berchel
Journal of Controlled Release, 2018, 278, pp.110 - 121. ⟨10.1016/j.jconrel.2018.03.035⟩
Article dans une revue hal-01774851v1
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Cold Atmospheric Plasma Parameters Investigation for Efficient Drug Delivery in HeLa Cells

Vinodini Vijayarangan , Anthony Delalande , Sébastien Dozias , Jean-Michel Pouvesle , Chantal Pichon
IEEE Transactions on Radiation and Plasma Medical Sciences, 2018, 2 (2), pp.109-115. ⟨10.1109/TRPMS.2017.2759322⟩
Article dans une revue hal-01940672v1

Nanostructured monolinolein miniemulsions as delivery systems: Role of the internal mesophase on cytotoxicity and cell internalization

Samuel Guillot , Fabienne Meducin , Kristina Poljak , Virginie Malard , Alexandra Foucault-Collet
International Journal of Pharmaceutics, 2017, 523 (1), pp.142 - 150. ⟨10.1016/j.ijpharm.2017.03.012⟩
Article dans une revue hal-01656547v1

Proteomic Analysis of the Chlorophyta Dunaliella New Strain AL-1 Revealed Global Changes of Metabolism during High Carotenoid Production

Faten Ben Amor , Fatma Elleuch , Hajer Ben Hlima , Matthieu Garnier , Bruno Saint-Jean
Marine drugs, 2017, 15 (9), pp.293. ⟨10.3390/md15090293⟩
Article dans une revue hal-02135151v1
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Microalgae amino acid extraction and analysis at nanomolar level using electroporation and capillary electrophoresis with laser-induced fluorescence detection

Reine Nehmé , Carla Atieh , Syntia Fayad , Bérengère Claude , Agnès Chartier
Journal of Separation Science, 2017, 40 (2), pp.558-566. ⟨10.1002/jssc.201601005⟩
Article dans une revue hal-01618682v1

MicroRNAs in Neurocognitive Dysfunctions: New Molecular Targets for Pharmacological Treatments?

Wissem Deraredj Nadim , Simion Viorel , Hélène Bénédetti , Chantal Pichon , Patrick Baril
Current Neuropharmacology, 2017, 15 (2), pp.260 - 275. ⟨10.2174/1570159X14666160709001441⟩
Article dans une revue hal-01618199v1

Self-Replicating RNA Vaccine Delivery to Dendritic Cells.

Thomas Démoulins , Pavlos C Englezou , Panagiota Milona , Nicola Ruggli , Nicola Tirelli
Methods in Molecular Biology, 2017, pp.37-75. ⟨10.1007/978-1-4939-6481-9_3⟩
Article dans une revue hal-01656568v1

Pharmacomodulation of microRNA Expression in Neurocognitive Diseases: Obstacles and Future Opportunities

Viorel Simion , Wissem Deraredj Nadim , Hélène Bénédetti , Chantal Pichon , Séverine Morisset-Lopez
Current Neuropharmacology, 2017, 15 (2), pp.276 - 290. ⟨10.2174/1570159X14666160630210422⟩
Article dans une revue hal-01618771v1

Peptides mediating DNA transport on microtubules and their impact on non-viral gene transfer efficiency

Patrick Midoux , Lucie Pigeon , Cristine Goncalves , Chantal Pichon
Bioscience Reports, 2017, 37 (5), pp.BSR20170995. ⟨10.1042/BSR20170995⟩
Article dans une revue hal-02068759v1
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Curcumin/poly(2-methyl-2-oxazoline-b-tetrahydrofuran-b-2-methyl-2-oxazoline) formulation: An improved penetration and biological effect of curcumin in F508del-CFTR cell lines

Cristine Gonçalves , Pierre Gomez , William Même , Bazoly Rasolonjatovo , David Gosset
European Journal of Pharmaceutics and Biopharmaceutics, 2017, 117, pp.168-181. ⟨10.1016/j.ejpb.2017.04.015⟩
Article dans une revue hal-01618274v1
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Cationic microbubbles and antibiotic-free miniplasmid for sustained ultrasound–mediated transgene expression in liver

Simona Manta , Gilles Renault , Anthony Delalande , Olivier Couture , Isabelle Lagoutte
Journal of Controlled Release, 2017, 262, pp.170 - 181. ⟨10.1016/j.jconrel.2017.07.015⟩
Article dans une revue hal-01656574v1

Production of DNA minicircles less than 250 base pairs through a novel concentrated DNA circularization assay enabling minicircle design with NF-κB inhibition activity

Thomas Thibault , Jéril Degrouard , Patrick Baril , Chantal Pichon , Patrick Midoux
Nucleic Acids Research, 2017, 45 (5), pp.e26 - e26. ⟨10.1093/nar/gkw1034⟩
Article dans une revue hal-01618796v1

Synthesis of α-amino-lipophosphonates as cationic lipids or co-lipids for DNA transfection in dendritic cells

Mathieu Berchel , Sohail Akhter , Wilfried Berthe , Cristine Gonçalvez , Marine Dubuisson
Journal of materials chemistry‎ B, 2017, J. Mater. Chem. B, 5, pp.6869-6881. ⟨10.1039/C7TB01080J⟩
Article dans une revue hal-01551638v1
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Macroalga Padina pavonica water extracts obtained by pressurized liquid extraction and microwave-assisted extraction inhibit hyaluronidase activity as shown by capillary electrophoresis

Syntia Fayad , Reine Nehmé , Mona Tannoury , Eric Lesellier , Chantal Pichon
Journal of Chromatography A, 2017, 1497, pp.19-27. ⟨10.1016/j.chroma.2017.03.033⟩
Article dans une revue hal-01618229v1

Positive radionuclide imaging of miRNA expression using RILES and the human sodium iodide symporter as reporter gene is feasible and supports a protective role of miRNA-23a in response to muscular atrophy

Viorel Simion , Julien Sobilo , Rudy Clemoncon , Sharuja Natkunarajah , Safia Ezzine
PLoS ONE, 2017, 12 (5), pp.e0177492. ⟨10.1371/journal.pone.0177492⟩
Article dans une revue hal-01618769v1

Nanoporous metal organic frameworks as hybrid polymer–metal composites for drug delivery and biomedical applications

Sarwar Beg , Mahfoozur Rahman , Atul Jain , Sumant Saini , Patrick Midoux
Drug Discovery Today Biosilico, 2017, 22 (4), pp.625-637. ⟨10.1016/j.drudis.2016.10.001⟩
Article dans une revue hal-02068701v1

Effect of IL-1β, TNF-α and IGF-1 on trans-endothelial passage of synthetic vectors through an in vitro vascular endothelial barrier of striated muscle

Jean-Pierre Gomez , Cristine Gonçalves , Chantal Pichon , Patrick Midoux
Gene Therapy, 2017, 24 (7), pp.416 - 424. ⟨10.1038/gt.2017.40⟩
Article dans une revue hal-01618260v1

Bile Salt Stabilized Vesicles (Bilosomes): A Novel Nano-Pharmaceutical Design for Oral Delivery of Proteins and Peptides

Javed Ahmad , Madhur Singhal , Saima Amin , Md. Rizwanullah , Sohail Akhter
Current Pharmaceutical Design, 2017, 23 (11), pp.1575 - 1588. ⟨10.2174/1381612823666170124111142⟩
Article dans une revue hal-01656515v1

Skin Immune Landscape: Inside and Outside the Organism

Florence Abdallah , Lily Mijouin , Chantal Pichon
Mediators of Inflammation, 2017, 2017, pp.1 - 17. ⟨10.1155/2017/5095293⟩
Article dans une revue hal-01622500v1
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Cationic gas-filled microbubbles for ultrasound-based nucleic acids delivery

Anthony Delalande , Colette Bastié , Lucie Pigeon , Simona Manta , Matthias Lebertre
Bioscience Reports, 2017, 37 (6), pp.BSR20160619. ⟨10.1042/BSR20160619⟩
Article dans une revue hal-02123147v1

Highly selective capture of minicircle DNA biopharmaceuticals by a novel zinc-histidine peptide conjugate

Vítor Gaspar , Carla Cruz , João A. Queiroz , Chantal Pichon , Ilídio J. Correia
Separation and Purification Technology, 2017, 174 (26), pp.417 - 424. ⟨10.1016/j.seppur.2016.10.054⟩
Article dans une revue hal-01618255v1

Nanotechnology Based Theranostic Approaches in Alzheimer's Disease Management: Current Status and Future Perspective

Javed Ahmad , Sohail Akhter , Md. Rizwanullah , Mohammad Ahmed Khan , Lucie Pigeon
Current Alzheimer Research, 2017, 14 (11), pp.1164-1181. ⟨10.2174/1567205014666170508121031⟩
Article dans une revue hal-02068674v1

Positive Bioluminescence Imaging of MicroRNA Expression in Small Animal Models Using an Engineered Genetic-Switch Expression System, RILES.

Patrick Baril , Chantal Pichon
Methods in Molecular Biology, 2016, 1372, pp.193-208
Article dans une revue hal-01405832v1

Nettle (Urtica dioica L.) as a source of antioxidant and anti-aging phytochemicals for cosmetic applications

Capucine Bourgeois , Cyrielle Corbin , Joël Doussot , Valérie Serrano , Jean-Raymond Vanier
Comptes Rendus. Chimie, 2016, 19 (9), pp.1090-1100. ⟨10.1016/j.crci.2016.03.019⟩
Article dans une revue hal-01607310v1

Intracellular Availability of pDNA and mRNA after Transfection: A Comparative Study among Polyplexes, Lipoplexes, and Lipopolyplexes

Cristine Goncalves , Sohail Akhter , Chantal Pichon , Patrick Midoux
Molecular Pharmaceutics, 2016, 13 (9), pp.3153-3163. ⟨10.1021/acs.molpharmaceut.6b00376⟩
Article dans une revue hal-02069071v1

Engineered Nanoparticles Against MDR in Cancer: The State of the Art and its Prospective

Javed Ahmad , Sohail Akhter , Mohammad Ahmed Khan , Muhammad Wahajuddin , Nigel H. Greig
Current Pharmaceutical Design, 2016, 22 (28), pp.4360-4373. ⟨10.2174/1381612822666160617112111⟩
Article dans une revue hal-02068807v1
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Enhanced lipid and biomass production by a newly isolated and identified marine microalga

Mouna Dammak , Sandra Mareike Haase , Ramzi Miladi , Faten Ben Amor , Mohamed Barkallah
Lipids in Health and Disease, 2016, 15, ⟨10.1186/s12944-016-0375-4⟩
Article dans une revue hal-01443238v1
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Study of the Effects of Betaine and/or C-Phycocyanin on the Growth of Lung Cancer A549 Cells In Vitro and In Vivo

Rea Bingula , Carmen Dupuis , Chantal Pichon , Jean-Yves Berthon , Marc Filaire
Journal of Oncology, 2016, 2016, pp.1-11. ⟨10.1155/2016/8162952⟩
Article dans une revue hal-02068827v1

TGF-beta-induced early gene-1 overexpression promotes oxidative stress protection and actin cytoskeleton rearrangement in human skin fibroblasts

Chloe Leduc , Lauren Sobilo , Hechmi Toumi , Philippe Mondon , Eric Lespessailles
Biochimica et Biophysica Acta:Biomembranes, 2016, 1860 (6), pp.1071 - 1078. ⟨10.1016/j.bbagen.2016.02.009⟩
Article dans une revue hal-01407918v1

Identification of a new oat β-amylase by functional proteomics

Nihed Ben Halima , Bassem Khemakhem , Imen Fendri , Hiroyuki Ogata , Patrick Baril
Biochimica et Biophysica Acta Proteins and Proteomics, 2016, 1864 (1), pp.52 - 61. ⟨10.1016/j.bbapap.2015.10.001⟩
Article dans une revue hal-01405835v1

Toxicity of Inorganic Nanoparticles Used in Targeted Drug Delivery and Other Biomedical Application: An Updated Account on Concern of Biomedical Nanotoxicology

Mohammad Zaki Ahmad , Basel Abdel-Wahab , Afroze Alam , Sobiya Zafar , Javed Ahmad
Journal of Nanoscience and Nanotechnology, 2016, 16 (8), pp.7873-7897. ⟨10.1166/jnn.2016.13032⟩
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Characterization of Positively Charged Lipid Shell Microbubbles with Tunable Resistive Pulse Sensing (TRPS) Method: A Technical Note

Simona Manta , Anthony Delalande , Michel Bessodes , Michel Francis Bureau , Daniel Scherman
Ultrasound in Medicine & Biology, 2016, 42 (2), pp.624 - 630. ⟨10.1016/j.ultrasmedbio.2015.10.010⟩
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Polyethylenimine-based polyplex delivery of self-replicating RNA vaccines

Thomas Démoulins , Panagiota Milona , Pavlos C. Englezou , Thomas Ebensen , Kai Schulze
Nanomedicine: Nanotechnology, Biology and Medicine, 2016, 12 (3), pp.711 - 722. ⟨10.1016/j.nano.2015.11.001⟩
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Synthesis of a trimannosylated-equipped archaeal diether lipid for the development of novel glycoliposomes

J. Barbeau , L. Lemiègre , A. Quelen , V. Malard , H. Gao
Carbohydrate Research, 2016, 435, pp.142--148. ⟨10.1016/j.carres.2016.10.003⟩
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Evidence for plasmid DNA exchange after polyplex mixing

L. Pigeon , C. Gonçalves , C. Pichon , P. Midoux
Soft Matter, 2016, 12 (33), pp.7012-7019. ⟨10.1039/c6sm00575f⟩
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EGR1 Regulates Transcription Downstream of Mechanical Signals during Tendon Formation and Healing

Ludovic Gaut , Nicolas Robert , Antony Delalande , Marie-Ange Bonnin , Chantal Pichon
PLoS ONE, 2016, 11 (11), pp.e0166237. ⟨10.1371/journal.pone.0166237.t001⟩
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Biological activity of Polynesian Calophyllum inophyllum oil extract on human skin cells

Phila Raharivelomanana , Jean-Luc J.-L. Ansel , E. Lupo , L. Mijouin , Samuel Guillot
Planta Medica, 2016, 82 (11-12), p. 961-966. ⟨10.1055/s-0042-108205⟩
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Gene delivery efficiency and intracellular trafficking of novel poly(allylamine) derivatives

Magdalena Wytrwal , Chloe Leduc , Michal Sarna , Cristine Goncalves , Mariusz Kepczynski
International Journal of Pharmaceutics, 2015, 478 (1), pp.372-382. ⟨10.1016/j.ijpharm.2014.11.053⟩
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HIF-regulated HO-1 gene transfer improves the post-ischemic limb recovery and diminishes TLR-triggered immune responses — Effects modified by concomitant VEGF overexpression

Agnieszka Jazwa , Mateusz Stoszko , Mateusz Tomczyk , Karolina Bukowska-Strakova , Chantal Pichon
Vascular Pharmacology, 2015, 71, pp.127-138. ⟨10.1016/j.vph.2015.02.011⟩
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Efficient gene delivery by sonoporation is associated with microbubble entry into cells and the clathrin-dependent endocytosis pathway

Anthony Delalande , Chloe Leduc , Patrick Midoux , Michiel Postema , Chantal Pichon
Ultrasound in Medicine & Biology, 2015, 41 (7), pp.1913-1926. ⟨10.1016/j.ultrasmedbio.2015.03.010⟩
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Le "Tamanu" et ses propriétés en dermocosmétique

Jean-Luc Ansel , Jean-Francois Butaud , M. Nicolas , G. Lecellier , Chantal Pichon
La Phytothérapie Européenne, 2015
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Monitoring the Spatiotemporal Activities of miRNAs in Small Animal Models Using Molecular Imaging Modalities

Patrick Baril , Safia Ezzine , Chantal Pichon
International Journal of Molecular Sciences, 2015, 16 (3), pp.4947-4972. ⟨10.3390/ijms16034947⟩
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Synthetic vectors for gene delivery: An overview of their evolution depending on routes of administration

Nawal Belmadi , Patrick Midoux , Pascal Loyer , Catherine Passirani , Chantal Pichon
Biotechnology Journal, 2015, 10 (9), pp.1370-1389. ⟨10.1002/biot.201400841⟩
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Nrf2-heme oxygenase-1 axis in mucoepidermoid carcinoma of the lung: Antitumoral effects associated with down-regulation of matrix metalloproteinases

Magdalena Tertil , Slawomir Golda , Klaudia Skrzypek , Urszula Florczyk , Kazimierz Weglarczyk
Free Radical Biology and Medicine, 2015, 89, pp.147-157. ⟨10.1016/j.freeradbiomed.2015.08.004⟩
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Lipid-based mRNA vaccine delivery systems

Patrick Midoux , Chantal Pichon
Expert Review of Vaccines, 2015, 14 (2), pp.221-234. ⟨10.1586/14760584.2015.986104⟩
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Gas-generating TPGS-PLGA microspheres loaded with nanoparticles (NIMPS) for co-delivery of minicircle DNA and anti-tumoral drugs

Vítor Gaspar , André F. Moreira , Elisabete C. Costa , João A. Queiroz , Fani Sousa
Colloids and Surfaces B: Biointerfaces, 2015, 134, pp.287 - 294. ⟨10.1016/j.colsurfb.2015.07.004⟩
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Enhanced Achilles tendon healing by fibromodulin gene transfer

Anthony Delalande , Marie-Pierre Gosselin , Arnaud Suwalski , William Guilmain , Chloé Leduc
Nanomedicine: Nanotechnology, Biology and Medicine, 2015, 11 (7), pp.1735 - 1744. ⟨10.1016/j.nano.2015.05.004⟩
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Minicircle DNA vectors for gene therapy: advances and applications

Vítor Gaspar , Duarte De Melo-Diogo , Elisabete Costa , André Moreira , João Queiroz
Expert Opinion on Biological Therapy, 2015, 15 (3), pp.353-379. ⟨10.1517/14712598.2015.996544⟩
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Folate-Targeted Multifunctional Amino Acid-Chitosan Nanoparticles for Improved Cancer Therapy

Vítor M. Gaspar , Elisabete C. Costa , João A. Queiroz , Chantal Pichon , Fani Sousa
Pharmaceutical Research, 2015, 32 (2), pp.562-577. ⟨10.1007/s11095-014-1486-0⟩
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Bioreducible poly(2-ethyl-2-oxazoline)–PLA–PEI-SS triblock copolymer micelles for co-delivery of DNA minicircles and Doxorubicin

Vítor Gaspar , Elisabete C. Costa , Duarte de Melo-Diogo , Frédéric Foucher , João A. Queiroz
Journal of Controlled Release, 2015, 213 (7), pp.175 - 191. ⟨10.1016/j.jconrel.2015.07.011⟩
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Emerging advances in cancer nanotheranostics with graphene nanocomposites: opportunities and challenges

Mahfoozur Rahman , Sohail Akhter , Mohammad Zaki Ahmad , Javed Ahmad , Richard Addo
Nanomedicine, 2015, 10 (15), pp.2405-2422. ⟨10.2217/nnm.15.68⟩
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Optimised amylases extraction from oat seeds and its impact on bread properties.

Nihed Ben Halima , Maha Borchani , Imen Fendri , Bassem Khemakhem , David Gosset
International Journal of Biological Macromolecules, 2015, 72, pp.1213-1221. ⟨10.1016/j.ijbiomac.2014.10.018⟩
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Lipopolyplexes comprising imidazole/imidazolium lipophosphoramidate, histidinylated polyethyleneimine and siRNA as efficient formulation for siRNA transfection

Cristine Gonçalves , Mathieu Berchel , Marie-Pierre Gosselin , Virginie Malard , Hervé Cheradame
International Journal of Pharmaceutics, 2014, 460 (1-2), pp.264-272. ⟨10.1016/j.ijpharm.2013.11.005⟩
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Increased adenovirus Type 5 mediated transgene expression due to RhoB down-regulation

Dragomira Majhen , Nikolina Stojanović , Dunja Vukić , Chantal Pichon , Chloé Leduc
PLoS ONE, 2014, 9 (1), pp.e86698
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Improved Minicircle DNA Biosynthesis for Gene Therapy Applications

Vítor M. Gaspar , Cláudio J. Maia , João A. Queiroz , Chantal Pichon , Ilídio J. Correia
Human gene therapy methods, 2014, 25 (2), pp.93-105. ⟨10.1089/hgtb.2013.020⟩
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Editorial: Current status and prospects on nucleic acid transfer

Tristan Montier , Chantal Pichon , Marc Blondel , Patrick Midoux
Biotechnology Journal, 2014, 9 (11), pp.1363-1364. ⟨10.1002/biot.201300510⟩
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NF-kB related transgene expression in mouse tibial cranial muscle after pDNA injection followed or not by electrotransfer.

S Mahindhoratep , H Ait Bouda , Nelly El Shafey , D Scherman , A Kichler
BBA - Biochimica et Biophysica Acta, 2014, 1840 (11), pp.3257-3263
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Regulation and novel action of thymidine phosphorylase in non-small cell lung cancer: crosstalk with Nrf2 and HO-1.

Magdalena Tertil , Klaudia Skrzypek , Urszula Florczyk , Kazimierz Weglarczyk , Halina Was
PLoS ONE, 2014, 9 (5), pp.e97070
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Effect of the alcohol consumption on osteocyte cell processes: a molecular imaging study.

Delphine B Maurel , Delphine Benaitreau , Christelle Jaffré , Hechmi Toumi , Hugues Portier
Journal of Cellular and Molecular Medicine, 2014, 18 (8), pp.1680-1693
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Improved gene transfer with histidine-​functionalized mesoporous silica nanoparticles

David Brevet , Ouahiba Hocine , Anthony Delalande , Laurence Raehm , Clarence Charnay
International Journal of Pharmaceutics, 2014, pp.197-205. ⟨10.1016/j.ijpharm.2014.05.020⟩
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Improved nuclear delivery of antisense 2′-Ome RNA by conjugation with the histidine-rich peptide H5WYG

Ulysse Asseline , Cristine Gonçalves , Chantal Pichon , Patrick Midoux
The Journal of Gene Medicine, 2014, 16 (7-8), pp.157-165. ⟨10.1002/jgm.2773⟩
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Protective effects of oat oil on deltamethrin-induced reprotoxicity in male mice

Nihed Ben Halima , Ahlem Ben Slima , Imen Moalla , Hamadi Fetoui , Chantal Pichon
Food and Function, 2014, 5 (9), pp.2070-2077. ⟨10.1039/c4fo00190g⟩
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Poly(2-ethyl-2-oxazoline)–PLA-g–PEI amphiphilic triblock micelles for co-delivery of minicircle DNA and chemotherapeutics

Vítor M. Gaspar , Cristine Gonçalves , Duarte de Melo-Diogo , Elisabete C. Costa , João A. Queiroz
Journal of Controlled Release, 2014, 189, pp.90-104. ⟨10.1016/j.jconrel.2014.06.040⟩
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Influence of pDNA availability on transfection efficiency of polyplexes in non-proliferative cells.

Benoit Maury , Cristine Gonçalves , Guillaume Tresset , Mehdi Zeghal , Hervé Cheradame
Biomaterials, 2014, 35 (22), pp.5977-5985. ⟨10.1016/j.biomaterials.2014.04.007⟩
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Lanthanide-Based, Near-Infrared Luminescent and Magnetic Lipoparticles: Monitoring Particle Integrity.

Sara Lacerda , Célia S Bonnet , Agnès Pallier , Sandrine Villette , Frédéric Foucher
Small, 2013, 9 (16), pp.2662-2666. ⟨10.1002/smll.201201923⟩
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An E3-14.7K Peptide that Promotes Microtubules-Mediated Transport of Plasmid DNA Increases Polyplexes Transfection Efficiency.

Lucie Pigeon , Cristine Gonçalves , David Gosset , Chantal Pichon , Patrick Midoux
Small, 2013, 9 (22), pp.3845-3851. ⟨10.1002/smll.201300217⟩
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Sub-cellular temporal and spatial distribution of electrotransferred LNA/DNA oligomer.

Julie Orio , Elisabeth Bellard , Houda Baaziz , Chantal Pichon , Peter Mouritzen
Journal of RNAi and Gene Silencing, 2013, 9, pp.479-85
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Ability of plasmid DNA complexed with histidinylated lPEI and lPEI to cross in vitro lung and muscle vascular endothelial barriers

Jean-Pierre Gomez , Chantal Pichon , Patrick Midoux
Gene, 2013, 525 (2), pp.182-190. ⟨10.1016/j.gene.2013.03.055⟩
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RILES, a novel method for temporal analysis of the in vivo regulation of miRNA expression.

Safia Ezzine , Georges Vassaux , Bruno Pitard , Benoit Barteau , Jean-Marc Malinge
Nucleic Acids Research, 2013, epub ahead of print. ⟨10.1093/nar/gkt797⟩
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Sensitive Detection of Peptide–Minicircle DNA Interactions by Surface Plasmon Resonance

Vítor Gaspar , Carla Cruz , João Queiroz , Chantal Pichon , Ilídio Correia
Analytical Chemistry, 2013, 85 (4), pp.2304-2311. ⟨10.1021/ac303288x⟩
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Protective effect of a Butea monosperma (Lam.) Taub. flowers extract against skin inflammation: Antioxidant, anti-inflammatory and matrix metalloproteinases inhibitory activities

Isabelle Krolikiewicz-Renimel , Thomas Michel , Emilie Destandau , Madhukar Reddy , Patrice André
Journal of Ethnopharmacology, 2013, 148 (2), pp.537-543. ⟨10.1016/j.jep.2013.05.001⟩
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Exogenous mRNA delivery and bioavailability in gene transfer mediated by piggyBac transposition

Solenne Bire , David Gosset , Gwenhael Jegot , Patrick Midoux , Chantal Pichon
BMC Biotechnology, 2013, 13, pp.1-15. ⟨10.1186/1472-6750-13-75⟩
Article dans une revue hal-01129780v1
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Sonoporation: mechanistic insights and ongoing challenges for gene transfer

Anthony Delalande , Spiros Kotopoulis , Michiel Postema , Patrick Midoux , Chantal Pichon
Gene, 2013, 525 (2), pp.191-199. ⟨10.1016/j.gene.2013.03.095⟩
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Gene transfer by histidylated lipopolyplexes: A dehydration method allowing preservation of their physicochemical parameters and transfection efficiency

Federico Perche , Olivier Lambert , Mathieu Berchel , Paul-Alain Jaffres , Chantal Pichon
International Journal of Pharmaceutics, 2012, 423 (1), pp.144 - 150. ⟨10.1016/j.ijpharm.2011.04.009⟩
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Ultrasound and microbubble-assisted gene delivery: recent advances and ongoing challenges.

Anthony Delalande , Michiel Postema , Nathalie Mignet , Patrick Midoux , Chantal Pichon
Ther Deliv, 2012, 3 (10), pp.1199-1215
Article dans une revue hal-00817350v1
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Real-time sonoporation through HeLa cells

Spiros Kotopoulis , Anthony Delalande , Chantal Pichon , Michiel Postema
AIP Conference Proceedings, 2012, NONLINEAR ACOUSTICS STATE-OF-THE-ART AND PERSPECTIVES: 19th International Symposium on Nonlinear Acoustics, 1474 (1), pp.271-274. ⟨10.1063/1.4749348⟩
Article dans une revue hal-03186072v2

Ultrasound and microbubbles assisted-gene transfer: what is next?

Lynne Rudd , Chantal Pichon , Anthony Delalande
Ultraschall in der Medizin, 2012, 33 (4), pp.391-3
Article dans une revue hal-02071821v1

Pyridine-based lanthanide complexes combining MRI and NIR luminescence activities.

Célia S Bonnet , Frédéric Buron , Fabien Caillé , Chad M Shade , Bohuslav Drahoš
Chemistry - A European Journal, 2012, 18 (5), pp.1419-31. ⟨10.1002/chem.201102310⟩
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Ultrasound and microbubble-assisted gene delivery: recent advances and ongoing challenges

Anthony Delalande , Michiel Postema , Nathalie Mignet , Patrick Midoux , Chantal Pichon
Therapeutic Delivery, 2012, 3 (10), pp.1199-1215. ⟨10.4155/TDE.12.100⟩
Article dans une revue hal-03193228v1

Gene transfer by chemical vectors, and endocytosis routes of polyplexes, lipoplexes and lipopolyplexes in a myoblast cell line.

Ludivine Billiet , Jean-Pierre Gomez , Mathieu Berchel , Paul-Alain Jaffres , Tony Le Gall
Biomaterials, 2012, 33 (10), pp.2980-2990. ⟨10.1016/j.biomaterials.2011.12.027⟩
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A fraction of neurofibromin interacts with PML bodies in the nucleus of the CCF astrocytoma cell line.

Fabienne Godin , Sandrine Villette , Béatrice Vallée , Michel Doudeau , Séverine Morisset-Lopez
Biochemical and Biophysical Research Communications, 2012, 418 (4), pp.689-94. ⟨10.1016/j.bbrc.2012.01.079⟩
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Supramolecular assemblies of histidinylated α-cyclodextrin in the presence of DNA scaffold during CDplexes formation.

Véronique Bennevault-Celton , Allan Urbach , Olivier Martin , Chantal Pichon , Philippe Guégan
Bioconjugate Chemistry, 2011, 22 (12), pp.2404-14. ⟨10.1021/bc200167p⟩
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Sonoporation at a low mechanical index

Anthony Delalande , Spiros Kotopoulis , Tijs Rovers , Chantal Pichon , Michiel Postema
Bubble Science, Engineering & Technology, 2011, 3 (1), pp.3-12
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Histidinylated linear PEI: a new efficient non-toxic polymer for gene transfer.

Emilie Bertrand , Cristine Gonçalves , Ludivine Billiet , Jean Pierre Gomez , Chantal Pichon
Chemical Communications, 2011, 47 (46), pp.12547-12549. ⟨10.1039/c1cc15716g⟩
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Low bone accrual is associated with osteocyte apoptosis in alcohol-induced osteopenia

D.B. Maurel , Christelle Jaffré , Gael Y. Rochefort , P.C. Aveline , N. Boisseau
BONE, 2011, 49 (3), pp.543-552. ⟨10.1016/j.bone.2011.06.001⟩
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Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA.

Federico Perche , Thierry Benvegnu , Mathieu Berchel , Loic Lebegue , Chantal Pichon
Nanomedicine: Nanotechnology, Biology and Medicine, 2011, 7 (4), pp.445-53. ⟨10.1016/j.nano.2010.12.010⟩
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Sonoporation at low mechanical index

A. Delalande , S. Kotopoulis , T. Rovers , C. Pichon , M. Postema
Bubble Science, Engineering & Technology, 2011, 3 (1), pp.3-12. ⟨10.1179/1758897911Y.0000000001⟩
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Protonation of lipids impacts the supramolecular and biological properties of their self-assembly.

Marie Breton , Jean-François Berret , Claudie Bourgaux , Teresa Kral , Martin Hof
Langmuir, 2011, 27 (20), pp.12336-45. ⟨10.1021/la202439s⟩
Article dans une revue hal-00720543v1

Low bone accrual is associated with osteocyte apoptosis in alcohol-induced osteopenia.

D. B. Maurel , Christelle Jaffré , G. Y. Rochefort , P. C. Aveline , Nathalie Boisseau
BONE, 2011, 49 (3), pp.543-52. ⟨10.1016/j.bone.2011.06.001⟩
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Selective gene delivery in dendritic cells with mannosylated and histidylated lipopolyplexes.

Federico Perche , David Gosset , Mathieu Mével , Marie-Laure Miramon , Jean-Jacques Yaouanc
Journal of Drug Targeting, 2011, 19 (5), pp.315-25. ⟨10.3109/1061186X.2010.504262⟩
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Ultrasound and microbubble-assisted gene delivery in Achilles tendons: long lasting gene expression and restoration of fibromodulin KO phenotype

Anthony Delalande , Ayache Bouakaz , Gilles Renault , Flore Tabareau , Spiros Kotopoulis
Journal of Controlled Release, 2011, 156 (2), pp.223-230. ⟨10.1016/j.jconrel.2011.08.020⟩
Article dans une revue hal-03195121v1

Transient transmembrane release of green fluorescent proteins with sonoporation

K. Kaddur , L. Lebegue , F. Tranquart , P. Midoux , C. Pichon
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2010, 57 (7), pp.1558-1567. ⟨10.1109/TUFFC.2010.1586⟩
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Ultrasound-assisted microbubbles gene transfer in tendons for gene therapy

Anthony Delalande , Michel-Francis Bureau , Patrick Midoux , Ayache Bouakaz , Chantal Pichon
Ultrasonics Sonochemistry, 2010, 50 (2), pp.269-272. ⟨10.1016/j.ultras.2009.09.035⟩
Article dans une revue hal-00529321v1
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Accelerated Achilles tendon healing by PDGF gene delivery with mesoporous silica nanoparticles

Arnaud Suwalski , Hinda Dabboue , Anthony Delalande , Sabine F. Bensamoun , Francis Canon
Biomaterials, 2010, 31 (19), pp.5237-5245. ⟨10.1016/j.biomaterials.2010.02.077⟩
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Modeling the lateral organization of collagen molecules in fibrils using the paracrystal concept

Jean Doucet , Fatma Briki , Aurélien Gourrier , Chantal Pichon , Laurie Gumez
Journal of Structural Biology, 2010, 173 (2), pp.197 - 201. ⟨10.1016/j.jsb.2010.11.018⟩
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Chemical vectors for gene delivery: uptake and intracellular trafficking

Chantal Pichon , Ludivine Billiet , Patrick Midoux
Current Opinion in Biotechnology, 2010, 21 (5), pp.640-645. ⟨10.1016/j.copbio.2010.07.003⟩
Article dans une revue hal-00602488v1

Molecular structure of tail tendon fibers in TIEG1 knockout mice using synchrotron diffraction technology

L. Gumez , S.F. Bensamoun , J. Doucet , O. Haddad , J.R. Hawse
Journal of Applied Physiology, 2010, 108 (6), pp.1706-1710. ⟨10.1152/japplphysiol.00356.2010⟩
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Uptake of Functionalized Mesoporous Silica Nanoparticles by Human Cancer Cells

Matthieu Fisichella , Hinda Dabboue , Sanjib Bhattacharyya , Gerald Lelong , Marie-Louise Saboungi
Journal of Nanoscience and Nanotechnology, 2010, 10 (4), pp.314-2324. ⟨10.1166/jnn.2010.1917⟩
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Chemical vectors for gene delivery: a current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers

Patrick Midoux , Chantal Pichon , Jean-Jacques Yaouanc , Paul-Alain Jaffres
British Journal of Pharmacology, 2009, 157 (2), pp.166-178. ⟨10.1111/j.1476-5381.2009.00288.x⟩
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An optimized extended DNA kappa B site that enhances plasmid DNA nuclear import and gene expression

Cristine Gonçalves , Maryvonne Ardourel , Martine Decoville , Gilles Breuzard , Patrick Midoux
The Journal of Gene Medicine, 2009, 11 (5), pp.401-411. ⟨10.1002/jgm.1312⟩
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Histidine-rich peptide: evidence for a single zinc-binding site on H5WYG peptide that promotes membrane fusion at neutral pH

Corinne Bure , Régine Maget , Agnès F. Delmas , Chantal Pichon , Patrick Midoux
Journal of Mass Spectrometry, 2009, 44 (1), pp.81-89. ⟨10.1002/jms.1473⟩
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Comparative gene transfer between cationic and thiourea lipoplexes

Marie Breton , Jeanne Leblond , Johanne Seguin , Patrick Midoux , Daniel Scherman
The Journal of Gene Medicine, 2009, 12 (1), pp.45-54. ⟨10.1002/jgm.1417⟩
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Involvement of histidines 11, 15 and 19 in the binding of zinc to the fusogenic H5WYG peptide

Corinne Bure , Chantal Pichon , Patrick Midoux
Journal of Mass Spectrometry, 2009, 44 (8), pp.1163-1170. ⟨10.1002/jms.1591⟩
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Polymer-Based Gene Delivery: A Current Review on the Uptake and Intracellular Trafficking of Polyplexes

Patrick Midoux , Gilles Breuzard , Jean-Pierre Gomez , Chantal Pichon
Current Gene Therapy, 2008, 8 (5), pp.335-352
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Novel neutral imidazole-lipophosphoramides for transfection assays

M. Mevel , C. Neveu , Cristine Goncalves , J.-J. Yaouanc , Chantal Pichon
Chemical Communications, 2008, 27, pp.3124-3126. ⟨10.1039/b805226c⟩
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Cationic Lipids Based on Phosphonate and Phosphoramidate Chemistry: Synthesis and Application to Gene Therapy

Mathieu Mével , Jean-Jacques Yaouanc , Pascal Laurent , Claude Clément , Dominique Cartier
Phosphorus, Sulfur, and Silicon and the Related Elements, 2008, 183 (2-3), pp.460-468. ⟨10.1080/10426500701761300⟩
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Extraction of green fluorescent proteins with sonoporation

Kadija Kaddur , Anthony Delalande , François Tranquart , Patrick Midoux , Chantal Pichon
Journal of the Acoustical Society of America, 2008, 123 (5), pp.3218-3218. ⟨10.1121/1.2933412⟩
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Low dose beta-blocker prevents ovariectomy-induced bone loss in rats without affecting heart functions.

N. Bonnet , Claude-Laurent Benhamou , L. Malaval , C. Goncalves , L. Vico
Journal of Cellular Physiology, 2008, 217 (3), pp.819-827. ⟨10.1002/jcp.21564⟩
Article dans une revue hal-00407988v1

Nuclear delivery of NFkappaB-assisted DNA/polymer complexes: plasmid DNA quantitation by confocal laser scanning microscopy and evidence of nuclear polyplexes by FRET imaging.

Gilles Breuzard , Magdalena Tertil , Cristine Gonçalves , Hervé Cheradame , Philippe Géguan
Nucleic Acids Research, 2008, 36 (12), pp.e71. ⟨10.1093/nar/gkn287⟩
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Comparison of tendon fiber structures between wild type and TIEG knockout mice using synchrotron microdiffraction

S. Bensamoun , L. Gumez , J. Hawse , M. Subramaniam , F. Briki
Computer Methods in Biomechanics and Biomedical Engineering, 2008, 11 (sup001), pp.29 - 30. ⟨10.1080/10255840802296889⟩
Article dans une revue hal-01391846v1

Recent advances in gene delivery with ultrasound and microbubbles

Chantal Pichon , Kadija Kaddur , Patrick Midoux , François Tranquart , Ayache Bouakaz
Journal of Experimental Nanoscience, 2008, 3 (1), pp.17-40. ⟨10.1080/17458080801993422⟩
Article dans une revue hal-00518203v1

Synthesis and transfection activity of new cationic phosphoramidate lipids: High efficiency of an imidazolium derivative

M. Mevel , Gilles Breuzard , J.-J. Yaouanc , J.-C. Clement , P. Lehn
ChemBioChem, 2008, 9 (9), pp.1462-1471. ⟨10.1002/cbic.200700727⟩
Article dans une revue hal-00518184v1

Intracellular trafficking and nuclear import of polyplexes by FRET coupled with cellular imaging

Gilles Breuzard , M. Tertil , Chantal Pichon , Patrick Midoux
Human Gene Therapy, 2007, 18, pp.1048
Article dans une revue hal-00275215v1

mRNA-based cancer vaccine: prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes

M. Mockey , E Bourseau , V Chandrashekhar , A. Chaudhuri , S. Lafosse
Cancer Gene Therapy, 2007, 14 (9), pp.802-814. ⟨10.1038/sj.cgt.7701072⟩
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mRNA-based cancer vaccine: prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes.

M. Mockey , E. Bourseau , V. Chandrashekhar , A. Chaudhuri , S. Lafosse
Cancer Gene Therapy, 2007, 14 (9), pp.802-14. ⟨10.1038/sj.cgt.7701072⟩
Article dans une revue hal-00318514v1

Sonopermeabilization: therapeutic alternative with ultrasound and microbubbles

K. Kaddur , P. Palanchon , F. Tranquart , C. Pichon , A. Bouakaz
Journal de Radiologie, 2007, 88 (11 part 2), pp.1777-1786
Article dans une revue hal-00282410v1

DNA/cationic polymer complex attachment on a human vascular endothelial cell monolayer exposed to a steady laminar flow

Eric Mennesson , Patrick Erbacher , Mateusz Kuzak , Claudine Kieda , Patrick Midoux
Journal of Controlled Release, 2006, 114 (3), pp.389-397. ⟨10.1016/j.jconrel.2006.06.006⟩
Article dans une revue hal-00112894v1

mRNA transfection of dendritic cells: synergistic effect of ARCA mRNA capping with Poly(A) chains in cis and in trans for a high protein expression level

M. Mockey , C. Goncalves , F.P. Dupuy , F.M. Lemoine , C. Pichon
Biochemical and Biophysical Research Communications, 2006, 340, pp.1062-1068. ⟨10.1016/j.bbrc.2005.12.105⟩
Article dans une revue hal-00088921v1

Transfection efficiency and uptake process of polyplexes in human lung endothetial cells: a comparative study in non-polarized and polarized cells

E. Mennesson , P. Erbacher , V. Piller , C. Kieda , P. Midoux
The Journal of Gene Medicine, 2005, 7, pp.729-738
Article dans une revue hal-00088642v1

Macropinocytosis of polyplexes and recycling of plasmid via the clathrin-dependant pathway impair the transfection efficiency into human hepatocarcinoma cells

C. Goncalves , E. Mennesson , R. Fuchs , Gorvel J.P. , Patrick Midoux
Molecular Therapy, 2004, 10, pp.373-385
Article dans une revue hal-00113047v1

Optimization of in vitro vascular cell transfection with non-viral vectors for in vivo applications

Ibrahim Elmadbouh , Patrick Rossignol , Olivier Meilhac , Roger Vranckx , Chantal Pichon
The Journal of Gene Medicine, 2004, 6 (10), pp.1112-1124
Article dans une revue hal-00014241v1

On the gene delivery efficacies of pH-sensitive cationic lipids via endosomal protonation: a chemical biology investigation

R.S. Singh , C. Gonçalves , P. Sandrin , C. Pichon , P. Midoux
Chemistry & biology, 2004, 11, pp.713-723
Article dans une revue hal-00088426v1

Non-viral vectors in cystic fibrosis gene therapy: progress and challenges

T. Montier , P. Delépine , C. Pichon , C. Férec , D.J. Porteous
Trends in biotechnology., 2004, 22, pp.586-592
Article dans une revue hal-00088424v1

Single histidine residue in head-group region is sufficient to impart remarkable gene transfection properties to cationic lipids: evidence for histidine-mediated membrane fusion at acidic pH

V Kumar , Chantal Pichon , M. Refregiers , B Guerin , P. Midoux
Gene Therapy, 2002, 10 (15), pp.1206 - 1215. ⟨10.1038/sj.gt.3301979⟩
Article dans une revue hal-01596052v1

Histidine containing peptides and polypeptides as nucleic acid vectors.

Patrick Midoux , Eric Le Cam , Dominique Coulaud , Etienne Delain , Chantal Pichon
Somatic Cell and Molecular Genetics, 2002, 27 (1-6), pp.27-47. ⟨10.1023/a:1022931923153⟩
Article dans une revue hal-03065331v1

Zinc improves gene transfer mediated by DNA/cationic polymer complexes

Chantal Pichon , Brigitte Guérin , Matthieu M. Refregiers , Christine Gonçalves , Paul Vigny
The Journal of Gene Medicine, 2002, 4 (5), pp.548 - 559. ⟨10.1002/jgm.303⟩
Article dans une revue hal-01596013v1

Poly[Lys-(AEDTP)]: A Cationic Polymer That Allows Dissociation of pDNA/Cationic Polymer Complexes in a Reductive Medium and Enhances Polyfection

Chantal Pichon , Eric Le Cam , Brigitte Guérin , Dominique Coulaud , Etienne Delain
Bioconjugate Chemistry, 2002, 13 (1), pp.76-82. ⟨10.1021/bc015503o⟩
Article dans une revue hal-03065338v1

Intracellular processing and stability of DNA complexed with histidylated polylysine conjugates

Christine Gonçalves , Chantal Pichon , Brigitte Guérin , Patrick Midoux
The Journal of Gene Medicine, 2002, 4 (3), pp.271-281. ⟨10.1002/jgm.277⟩
Article dans une revue hal-02135970v1

Histidine-rich peptides and polymers for nucleic acids delivery.

Chantal Pichon , C Gonçalves , P. Midoux
Advanced Drug Delivery Reviews, 2001, 53 (1), pp.75-94
Article dans une revue hal-02135973v1

Marek’s disease virus (MDV) homologues of herpes simplex virus type 1 UL49 (VP22) and UL48 (VP16) genes: high-level expression and characterization of MDV-1 VP22 and VP16

Fabien Dorange , Slimane El Mehdaoui , Chantal Pichon , Pierre Coursaget , Jean-François Vautherot
Journal of General Virology, 2000, 81 (9), pp.2219-2230. ⟨10.1099/0022-1317-81-9-2219⟩
Article dans une revue hal-02135997v1

Histidylated polylysine as a synthetic vector for gene transfer into immortalized cystic fibrosis airway surface and airway gland serous cells

Isabelle Fajac , J.C Allo , Evelyne Souil , Marc Merten , Chantal Pichon
The Journal of Gene Medicine, 2000, 2 (5), pp.368-378. ⟨10.1002/1521-2254(200009/10)2:5<368::AID-JGM118>3.0.CO;2-F⟩
Article dans une revue hal-02135988v1

Histidylated oligolysines increase the transmembrane passage and the biological activity of antisense oligonucleotides

Chantal Pichon , Mahajoub Bello Roufaï , Michel Monsigny , Patrick Midoux
Nucleic Acids Research, 2000, 28 (2), pp.504-512. ⟨10.1093/nar/28.2.504⟩
Article dans une revue hal-02135979v1

Intracellular Localization of Oligonucleotides: Influence of Fixative Protocols

Chantal Pichon , Michel Monsigny , Annie-Claude Roche
Antisense and Nucleic Acid Drug Development, 1999, 9 (1), pp.89-93. ⟨10.1089/oli.1.1999.9.89⟩
Article dans une revue hal-02135999v1

Glycotargeting: the preparation of glyco-amino acids and derivatives from unprotected reducing sugars.

M Monsigny , C. Quétard , S. Bourgerie , D. Delay , Chantal Pichon
Biochimie, 1998, 80 (2), pp.99-108
Article dans une revue hal-02136005v1

Fluorescent labelling of unmodified phosphorothioate oligodeoxynucleotides: Synthesis and characterization

A.J. Stewart , Chantal Pichon , Patrick Midoux , R. Mayer , Michel Monsigny
New Journal of Chemistry, 1997, 21 (1), pp.87-98
Article dans une revue hal-02161369v1

Cytosolic and Nuclear Delivery of Oligonucleotides Mediated by an Amphiphilic Anionic Peptide

Chantal Pichon , Isabelle Freulon , Patrick Midoux , Roger Mayer , Michel Monsigny
Antisense and Nucleic Acid Drug Development, 1997, 7 (4), pp.335-343. ⟨10.1089/oli.1.1997.7.335⟩
Article dans une revue hal-02136009v1

Intracellular routing and inhibitory activity of oligonucleopeptides containing a KDEL motif.

C Pichon , K Arar , A. Stewart , M Dodon , L Gazzolo
Molecular Pharmacology, 1997, 51 (3), pp.431-8
Article dans une revue hal-02124430v1

Enhanced biological activity of antisense oligonucleotides complexed with glycosylated poly-L-lysine.

A. Stewart , Chantal Pichon , L Meunier , P Midoux , M. Monsigny
Molecular Pharmacology, 1996, 50 (6), pp.1487-94
Article dans une revue hal-02136015v1

A monoclonal antibody inhibits adhesion to fibronectin and vitronectin of a colon carcinoma cell line and recognizes the integrins alpha v beta 3, alpha v beta 5, and alpha v beta 6.

R. Lehmann , C Rabenandrasana , R. Tamura , J Lissitzky , V. Quaranta
Cancer Research, 1994, 54 (8), pp.2102-7
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Surface distribution of the EGF receptor during differentiation of the human colon carcinoma cell line HT29-D4.

M Lehmann , M Remacle-Bonnet , F Garrouste , J. Luis , C Rabenandrasana
Journal of receptor research, 1994, 14 (5), pp.319-33
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Expression of type I, but not type II insulin-like growth factor receptor on both undifferentiated and differentiated HT29 human colon carcinoma cell line.

M Remacle-Bonnet , J Culouscou , Fl Garrouste , C Rabenandrasana , J. Marvaldi
Journal of Clinical Endocrinology and Metabolism, 1992, 75 (2), pp.609-616. ⟨10.1210/jcem.75.2.1322432⟩
Article dans une revue hal-02136045v1

Combination of culture on collagen gels and glucose starvation for cloning human colon cancer cells

Maxime Lehmann , Chantal Rabenandrasana , Jean-Baptiste Rognoni , Bernard Verrier , Jacques Marvaldi
Cytotechnology, 1991, 5 (2), pp.117-127. ⟨10.1007/bf00365428⟩
Article dans une revue hal-02136051v1

The concentration of glucose in the culture medium determines the effect of suramin on the growth and differentiation of the human colonic adenocarcinoma cell clone HT29-D4.

C Rabenandrasana , S. Baghdiguian , M Roccabianca , M. Brunet , J. Marvaldi
Cancer Letters, 1990, 53 (2-3), pp.109-15
Article dans une revue hal-02136055v1

CD4 molecules are restricted to the basolateral membrane domain of in vitro differentiated human colon cancer cells (HT29-D4).

C Rabenandrasana , S. Baghdiguian , J. Marvaldi , J. Fantini
FEBS Letters, 1990, 265 (1-2), pp.75-9
Article dans une revue hal-02136057v1

Quantitative determination of Andrographolide and related compounds in Andrographis paniculata extracts and biological evaluation of their anti-inflammatory activity

Emmanuelle Villedieu Villedieu-Percheron , Véronique Ferreira , Joana Filomena Campos , Emilie Destandau , Chantal Pichon
Proetos, Charlampos. The Benefits of Plant Extracts for Human Health, MDPI Books, pp.129-140, 2021, 978-3-03943-851-8. ⟨10.3390/books978-3-03943-852-5⟩
Chapitre d'ouvrage hal-03652226v1

Microbubbles for Nucleic Acid Delivery in Liver Using Mild Sonoporation

Nathalie Mignet , Corinne Marie , Anthony Delalande , Simona Manta , Johanne Seguin
Nanotechnology for Nucleic Acid Delivery, pp.377-387, 2019, Methods in Molecular Biology, ⟨10.1007/978-1-4939-9092-4_25⟩
Chapitre d'ouvrage hal-02123117v1

Polyallylamine Derivatives: Novel NonToxic Transfection Agents

Magdalena Wytrwal , Chantal Pichon
Methods in molecular biology, pp.159-174, 2016, ⟨10.1007/978-1-4939-3718-9_10⟩
Chapitre d'ouvrage hal-02071774v1

Mannosylated and Histidylated LPR Technology for Vaccination with Tumor Antigen mRNA

Chantal Pichon , Patrick Midoux
Synthetic Messenger RNA and Cell Metabolism Modulation, pp.247-274, 2013, ⟨10.1007/978-1-62703-260-5_16⟩
Chapitre d'ouvrage hal-02070913v1

Histidine containing peptides and polypeptides as nucleic acid vectors

P. Midoux , E. Lecam , D. Coulaud , E. Delain , C. Pichon
Luo D., Saltzman W.M. Synthetic DNA Delivery Systems, Kluwer Academic/Plenum Publishers, New-York, pp.23-44, 2003
Chapitre d'ouvrage hal-00115810v1

Peptide-based gene delivery systems

P. Midoux , C. Pichon
Mahato R.I., Kim S.W. Pharmaceutical perspectives of nucleic acid-based, Taylor & Francis, London and New York, pp.334-366, 2002
Chapitre d'ouvrage hal-00115804v1

Glycoconjugates as vectors for gene and oligonucleotide delivery

M. Monsigny , C. Quétard , E. Duverger , C. Pichon , V. Altemayer
Aubery M. Glycans in cellular interaction and recognition: therapeutic, Harwood Academic Publishers, Amsterdam, pp.193-215, 2002
Chapitre d'ouvrage hal-00115807v1

Histidylated polycationic molecules for nucleic acids transfer

P. Midoux , C. Pichon
Pandalai S.G. Recent research developments in bioconjugate chemistry, Transworld Research Network, Trivandrum, pp.95-111, 2002
Chapitre d'ouvrage hal-00115805v1