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Analyzing the Folding and Binding Steps of an Intrinsically Disordered Protein by Protein Engineering

Daniela Bonetti , Francesca Troilo , Angelo Toto , Maurizio Brunori , Sonia Longhi , et al.
Biochemistry, 2017, 56 (29), pp.3780 - 3786. ⟨10.1021/acs.biochem.7b00350⟩
Article dans une revue hal-01802841v1
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Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein.

Stefano Gianni , Carlo Camilloni , Rajanish Giri , Angelo Toto , Daniela Bonetti , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (39), pp.14141-6. ⟨10.1073/pnas.1405233111⟩
Article dans une revue pasteur-01180909v1
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Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system.

Rajanish Giri , Angela Morrone , Angelo Toto , Maurizio Brunori , Stefano Gianni
Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (37), pp.14942-7. ⟨10.1073/pnas.1307337110⟩
Article dans une revue pasteur-01025444v1

Binding induced folding: Lessons from the kinetics of interaction between NTAIL and XD

Angelo Toto , Francesca Troilo , Lorenzo Visconti , Francesca Malagrinò , Christophe Bignon , et al.
Archives of Biochemistry and Biophysics, 2019, 671, pp.255-261. ⟨10.1016/j.abb.2019.07.011⟩
Article dans une revue hal-02341649v1
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The mechanism of binding of the second PDZ domain from the Protein Tyrosine Phosphatase-BL to the Adenomatous Polyposis Coli tumor suppressor.

Eva Di Silvio , Daniela Bonetti , Angelo Toto , Angela Morrone , Stefano Gianni
Protein Engineering, Design and Selection, 2014, 27 (8), pp.249-53. ⟨10.1093/protein/gzu022⟩
Article dans une revue pasteur-01181359v1
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Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate

Candice Gautier , Francesca Troilo , Florence Cordier , Francesca Malagrinò , Angelo Toto , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (33), pp.19963 - 19969. ⟨10.1073/pnas.2004138117⟩
Article dans une revue hal-02990193v1
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Regulation of the Human Phosphatase PTPN4 by the inter-domain linker connecting the PDZ and the phosphatase domains

Célia Caillet-Saguy , Angelo Toto , Raphaël Guérois , Pierre Maisonneuve , Eva Di Silvio , et al.
Scientific Reports, 2017, 7, pp.7875. ⟨10.1038/s41598-017-08193-6⟩
Article dans une revue hal-02192076v1
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Folding Mechanism of the SH3 Domain from Grb2

Francesca Troilo , Daniela Bonetti , Carlo Camilloni , Angelo Toto , Sonia Longhi , et al.
Journal of Physical Chemistry B, 2018, 122 (49), pp.11166-11173. ⟨10.1021/acs.jpcb.8b06320⟩
Article dans une revue hal-02094551v1
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The kinetics of folding of frataxin.

Daniela Bonetti , Angelo Toto , Rajanish Giri , Angela Morrone , Domenico Sanfelice , et al.
Physical Chemistry Chemical Physics, 2014, 16 (14), pp.6391-7. ⟨10.1039/c3cp54055c⟩
Article dans une revue pasteur-01181218v1
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The mechanism of binding of the KIX domain to the mixed lineage leukemia protein and its allosteric role in the recognition of c-Myb.

Angelo Toto , Rajanish Giri , Maurizio Brunori , Stefano Gianni
Protein Science, 2014, 23 (7), pp.962-9. ⟨10.1002/pro.2480⟩
Article dans une revue pasteur-01181353v1
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MICADO SCAO: to be or not to be... in MAIT

Yann Clenet , Tristan Buey , Eric Gendron , Sonia Karkar , Fabrice Vidal , et al.
Adaptive Optics for Extremely Large Telescopes 7th Edition, 2023, ⟨10.13009/AO4ELT7-2023-099⟩
Proceedings/Recueil des communications hal-04402874v1
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Lab demonstration of wavefront reconstruction for the fragmented aperture of the ELT

Arielle Bertrou-Cantou , Eric Gendron , Gérard Rousset , Fabrice Vidal , Jordan Raffard , et al.
Adaptive Optics for Extremely Large Telescopes 7th Edition, ONERA, Jun 2023, Avignon, France. ⟨10.13009/AO4ELT7-2023-126⟩
Communication dans un congrès hal-04402863v1